GDNF: A cytokine at the interface of TGF-βs and neurotrophins

Cell and Tissue Research

Volumn 286, Issue 2, 1996, Pages 175-178

  Unsicker, K ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NEURITE PROMOTING FACTOR; NEUROTROPHIN; TRANSFORMING GROWTH FACTOR BETA;

PRIORITY JOURNAL; SHORT SURVEY; TISSUE DISTRIBUTION;

ANIMALS; CYTOKINES; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029804715     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410050686     Document Type: Short Survey

References (44)

1. Arenas E, Trupp M, Åkerud P, Ibáñez CF (1995) GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron 15:1465-1473
2. Beck KD, Valverde J, Alexi T, Poulsen K, Moffat B, Vandlen RA, Rosenthal A, Hefti F (1995) Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature 373:339-341
3. Buj-Bello A, Buchman VL, Horton A, Rosenthal A, Davies AM (1995) GDNF is an age-specific survival factor for sensory and autonomic neurons. Neuron 15:821-828
4. Choi-Lundberg DL, Bohn MC (1995) Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat. Dev Brain Res 85:80-88
5. Durbec P, Marcos-Gutierrez CV, Kilkenny C, Grigoriou M, Suvanto P, Wartiovaara K, Smith D, Ponder B, Constantini F, Saarma M, Sariola H, Pachnis V (1996) Glial cell line-derived neurotrophic factor signalling through the Ret receptor tyrosine kinase. Nature 381:789-793
6. Ebendal T, Tomac A, Hoffer BJ, Olson L (1995) Glial cell line-derived neurotrophic factor stimulates fiber formation and survival in cultured neurons from peripheral autonomic ganglia. J Neurosci Res 40:276-284
7. Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, Simmerman L, Russell D, Martin D, Lapchak PA, Collins F, Hoffer BJ, Gerhardt GA (1996) Functional recovery in parkinsonian monkeys treated with GDNF. Nature 380:252-255
8. Henderson CE, Phillips HS, Pollock RA, Davies AM, Lemeulle C, Armanini M, Simpson LC, Moffet B, Vandlen RA, Koliatsos VE, Rosenthal A (1994) GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science 266:1062-1068
9. Hoffer BJ, Huffman A, Bowenkamp K, Huettl P, Hudson J, Martin D, Lin L-FH, Gerhardt GA (1994) Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaininergic neurons in vivo. Neurosci Lett 182:107-111
10. Hofstra RMW, Landsvater RM, Ceccherini I, Stulp RM, Stelwagen T, Luo Y, Pasini B, Höppener JWM, Ploos van Amstel HK, Romeo G, Lips CJM, Buys CHM (1994) A mutation in the RET protooncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature 367:375-376
11. Hudson J, Granholm A-C, Gerhardt GA, Henry MA, Hoffman A, Biddle P, Leela NS, Mackerlova L, Lile JD, Collins F, Hoffer BJ (1995) Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain Res Bull 36:425-432
12. Humpel C, Hotter B, Strömberg I, Bektesh S, Collins F, Olson L (1994) Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger RNA in response to kainate-induced excitation. Neuroscience 59:791-795
13. Kearns CM, Gash DM (1995) GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo. Brain Res 672:104-111
14. Kingsley DM (1994) The TGF-beta superfamily - new members, new receptors, and new genetic tests of function in different organisms. Gene Dev 8:133-146
15. Kotzbauer PT, Lampe PA, Johnson EM, Milbrandt J (1996) In: Signaling in neuronal development, differentiation and degeneration. Keystone Symposia on molecular and cellular biology. Taos, NM, March 27-April 2, 1996, p. 136
16. + toxicity. FMBO J 14:736-742
17. Li LX, Wu WT, Lin LFH, Lei M, Oppenheim RW, Houenou LJ (1995) Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc Natl Acad Sci USA 92:9771-9775
18. Lin L-FH, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132
19. Lin L-FH, Zhang TJ, Collins F, Armes LG (1994) Purification and initial characterization of rat B49 glial cell line-derived neurotrophic factor. J Neurochem 63:758-768
20. Martin D, Miller G, Rosendahl M, Russell DA (1995) Potent inhibitory effects of glial derived neurotrophic factor against kainic acid mediated seizures in the rat. Brain Res 683:172-178
21. Moore MW, Klein RD, Farinas I, Sauer H, Armanini M, Phillips H, Reichardt LF, Ryan AM, Carver-Moore K, Rosenthal A (1996) Renal and neuronal abnormalities in mice lacking GDNF. Nature 382:76-79
22. Mount HTJ, Dean DO, Alberch J, Dreyfus CF, Black IB (1995) Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proc Natl Acad Sci USA 92:9092-9096
23. Oppenheim RW, Houenou LJ, Johnson JE, Lin L-FH, Li L, Lo AC, Newsome AL, Prevette DM, Wang S (1995) Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature 373:344-346
24. Pasini B, Ceccherin I, Romeo G (1996) RET mutations in human disease. TIG 12:138-144
25. Pichel J, Shen L, Drago J, Hoffer B, Saarma M, Sariola H, Westphal II (1996) Defects in cnteric innervation and ureteric branching of the metanephric kidney in mice lacking GDNF. Nature 382:73-76
26. Romeo G, Ronchetto P, Luo Y, Barone V, Seri M, Ceccherini I, Pasini B, Bocciardi R, Lerone M, Kääriäinen H, Martucciello G (1994) Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease. Nature 367:377-378
27. Sanchez MR, Silos-Santiago I, Frisen J, He B, Lira SA, Barbacid M (1996) Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382:70-73
28. Sauer H, Rosenblad C, Björklund A (1995) Glial cell line-derived neurotrophic factor but not transforming growth factor β3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc Natl Acad Sci USA 92:8935-8939
29. Schaar DG, Sieber BA, Dreyfus CF, Black IB (1993) Regional and cell-specific expression of GDNF in rat brain. Exp Neurol 124:368-371
30. Schindelhauer D, Schuffenhauer S, Gasser T, Steinkasserer A, Meitinger T (1995) The gene coding for glial cell line derived neurotrophic factor (GDNF) maps to chromosome 5p12-p 13.1. Genomics 28:605-607
31. Schmidt-Kastner R, Tomac A, Hoffer B, Bektesh S, Rosenzweig B, Olson L (1994) Glial cell-line derived neurotrophic factor (GDNF) mRNA upregulation in striatum and cortical areas after pilocarpine-induced status epilepticus in rats. Mol Brain Res 26:325-330
32. Schuchardt A, D'Agati V, Larsson-Blomberg L, Constanti F, Pachnis V (1994) Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367:380-383
33. Springer JE, Mu X, Bergmann LW, Trojanowski JQ (1994) Expression of GDNF mRNA in rat and human nervous tissue. Exp Neurol 127:167-170
34. Strömberg I, Bjorklund L, Johansson M, Tomac A, Collins F, Olson L, Hotter B, Humpel C (1993) Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Exp Neurol 124:401-412
35. Suter-Crazzolara C, Unsicker K (1994) CDNF is expressed in two forms in many tissues outside the CNS. Neuroreport 5:2486-2488
36. Suter-Crazzolara C, Unsicker K (1996) GDNF mRNA levels are induced by FGF-2 in rat C6 glioblastoma cells. Mol Brain Res (in press)
37. Suter-Crazzolara C, Farkas L, Unsicker K (1995) Regulation of expression and functions of GDNF on neural cells. Soc Neurosci Abstr 21:225.22
38. Tomac A, Lindqvist E, Lin L-FH, Ögren SO, Young D, Hoffer BJ, Olson L (1995a) Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373:335-339
39. Tomac A, Widenfalk J, Lin LFH, Kohno T, Ebendal T, Hoffer BJ, Olson L (1995b) Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proc Natl Acad Sci LISA 92:8274-8278
40. Trok K, Hoffer B, Olson L (1996) Glial cell line-derived neurotrophic factor enhances survival and growth of prenatal and postnatal spinal cord transplants. Neuroscience 71:231-241
41. Trupp M, Rydén M, Jörnvall H, Funakoshi H, Timmusk T, Arenas E, Ibáñez. CF (1995) Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol 130:137-148
42. Trupp M, Arenas E, Fainzilber M, Nilsson AS, Sieber BA, Grigoriou M, Kilkenny C, Salazar-Grueso E, Pachnis V, Arume U, Sariola H, Saarma M, Ibanez CF (1996) Functional receptor for glial cell line-derived neurotrophic factor encoded by the c-ret proto-oncogene product Nature 381:785-789
43. Yan Q, Matheson C, Lopez OT (1995) In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373:341-344
44. Zurn AD, Baetge EE, Hammang JP, Tan SA, Aebischer P (1994) Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. Neuroreport 6:113-118