TGF-β rescues target-deprived preganglionic sympathetic neurons in the spinal cord

European Journal of Neuroscience

Volumn 8, Issue 1, 1996, Pages 202-210

  Blottner, Dieter ^b   Wolf, Nicole ^a   Lachmund, Astrid ^a   Flanders, Kathleen C ^c   Unsicker, Klaus ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Adrenal medullary chromaffin cells; Growth factors; Neuroprotection; Preganglionic sympathetic spinal cord neurons; TGF

Indexed keywords

CYTOCHROME C; FIBROBLAST GROWTH FACTOR 2; GELFOAM; IODINE 125; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2;

ADRENAL MEDULLA; ADRENALECTOMY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHROMAFFIN CELL; CONTROLLED STUDY; FEMALE; INNERVATION; NEUROPROTECTION; NONHUMAN; PREGANGLIONIC NERVE CELL; PRIORITY JOURNAL; RAT; SPINAL CORD; SPINAL CORD NERVE CELL; SYMPATHETIC NERVE CELL; THORACIC SPINAL CORD;

ADRENAL CORTEX; ADRENAL MEDULLA; ANIMALS; AXONAL TRANSPORT; CELLS, CULTURED; CHROMAFFIN GRANULES; CYTOCHROME C GROUP; FEMALE; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION; IODINE RADIOISOTOPES; NADPH DEHYDROGENASE; NEURONS; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; RNA, MESSENGER; SPINAL CORD; SYMPATHETIC NERVOUS SYSTEM; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029671150     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1996.tb01181.x     Document Type: Article

References (6)

1. Anderson, C. R. (1992) NADPH-diaphorase-positive neurons in the rat spinal cord include a subpopulation of autonomic preganglionic neurons. Neurosci. Lett., 139, 280-284.
2. Appel, N. M. and Elde, R. P. (1988) The intermediolateral column of the spinal cord is comprised of target-specific subnuclei: evidence from retrograde transport studies and immunohistochemistry. J. Neurosci., 8, 1767-1775.
3. Barde, Y. A. (1989) Trophic factors and neuronal survival. Neuron, 2, 1525-1534.
4. Bieger, S., Lachmund, A., Meyer, V., Hüll, M., Krieglstein, K. and Unsicker, K. (1993) Synthesis and release of FGF, TGF-β and other growth factors by cultured chromaffin cells. Soc. Neurosci. Abstr., 19 (1), p.246.
5. Blottner, D. and Baumgarten, H. G. (1992a) Nitric oxide synthase (NOS)-containing sympathoadrenal cholinergic neurons of the rat IML-cell column. Evidence from histochemistry, immunohistochemistry and retrograde labelling. J. Comp. Neurol., 316, 45-55.
6. Blottner, D. and Baumgarten, H. G. (1992b) Basic fibroblast growth factor prevents neuronal death and atrophy of retrogradely labelled preganglionic neurons in vivo. Exp. Neurol., 118, 35-46.