Identification of a naturally occurring recombinant Epstein-Barr virus isolate from New Guinea that encodes both type 1 and type 2 nuclear antigen sequences

Journal of Virology

Volumn 70, Issue 7, 1996, Pages 4829-4833

  Burrows, Jacqueline M ^a   Khanna, Rajiv ^a   Sculley, Tom B ^a   Alpers, Michael P ^b   Moss, Denis J ^a   Burrows, Scott R ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS ANTIGEN;

ARTICLE; DNA SEQUENCE; EPSTEIN BARR VIRUS; GENE SEQUENCE; HUMAN; HUMAN CELL; LYMPHOCYTE; MALE; PAPUA NEW GUINEA; PRIORITY JOURNAL; SEQUENCE ANALYSIS; VIRUS CHARACTERIZATION; VIRUS ISOLATION; VIRUS RECOMBINANT;

EID: 0029888376     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.7.4829-4833.1996     Document Type: Article

References (33)

1. Adldinger, H. K., H. Delius, U. K. Freest, J. Clarke, and G. W. Bornkamm. 1985. A putative transforming gene of the Jijoye virus differs from that of Epstein-Barr virus prototypes. Virology 141:221-234.
2. Aitken, C., S. K. Sengupta, C. Aedes, D. J. Moss, and T. B. Sculley. 1994. Heterogeneity within the Epstein-Barr virus nuclear antigen 2 gene in different strains of Epstein-Barr virus. J. Gen. Virol. 75:95-100.
3. Baer, R., A. T. Bankier, M. D. Biggin, P. L. Deininger, P. J. Farrell, T. J. Gibson, G. Hatfull, G. S. Hudson, S. C. Satchwell, C. Sequin, P. S. Tuffnell, and B. G. Barrell. 1984. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature (London) 310:207-211.
4. Bellwood, P. S. 1989. The colonization of the Pacific: some current hypotheses, p. 1-59. In A. V. S. Hill and S. W. Serjeantson (ed.), The colonization of the Pacific: a genetic trail. Clarendon Press, Oxford.
5. Buisson, M., P. Morand, O. Genoulaz, M.-J. Bourgeat, M. Micoud, and J.-M. Seigneurin. 1994. Changes in the dominant Epstein-Barr virus type during human immunodeficiency virus infection. J. Gen. Virol. 75:431-437.
6. Burrows, J. M., S. R. Burrows, L. M. Poulsen, T. B. Sculley, D. J. Moss, and R. Khanna. 1996. Unusually high frequency of Epstein-Barr virus genetic variants in Papua New Guinea that can escape cytotoxic T-cell recognition: implications for virus evolution. J. Virol. 70:2490-2496.
7. Burrows, S. R., J. Gardner, R. Khanna, T. Steward, D. J. Moss, S. Rodda, and A. Suhrbier. 1994. Five new cytotoxic T cell epitopes identified within Epstein-Barr virus nuclear antigen 3. J. Gen. Virol. 75:2489-2493.
8. Burrows, S. R., T. B. Sculley, I. S. Misko, C. Schmidt, and D. J. Moss. 1990. An Epstein-Barr virus-specific cytotoxic T cell epitope in EBV nuclear antigen 3 (EBNA 3). J. Exp. Med. 171:345-349.
9. Cohen, J. I., F. Wang, and E. Kieff. 1991. Epstein-Barr virus nuclear protein 2 mutations define essential domains for transformation and transactivation. J. Virol. 65:2545-2554.
10. Dambaugh, T., K. Hennessy, L. Chamnaukit, and E. Kieff. 1984. U2 region of Epstein-Barr virus DNA may encode Epstein-Barr virus nuclear antigen 2. Proc. Natl. Acad. Sci. USA 81:7632-7636.
11. Fresen, K.-O., M.-S. Cho, and H. zur Hausen. 1978. Recovery of transforming EBV from non-producer cells after superinfection with non-transforming P3HR-1 EBV. Int. J. Cancer 22:378-383.
12. Gan, Y.-J., P. Shirley, Y. Zeng, and J. W. Sixbey. 1993. Human oropharyngeal lesions with a defective Epstein-Barr virus that disrupts viral latency. J. Infect. Dis. 168:1349-1355.
13. Gratama, J. W., M. A. P. Oosterveer, W. Weimar, K. Sintnicolaas, W. Sizoo, R. L. H. Bolhuis, and I. Ernberg. 1994. Detection of multiple "Ebnotypes" in individual Epstein-Barr virus carriers following lymphocyte transformation by virus derived from peripheral blood and oropharynx, J. Gen. Virol. 75: 85-94.
14. Greenspan, J. S., D. Greenspan, E. T. Lennette, D. I. Abrams, M. A. Conant, V. Petersen, and U. K. Freese. 1985. Replication of Epstein-Barr virus within the epithelial cells of oral "hairy'' leukoplakia, an AIDS-associated lesion. N. Engl. J. Med. 313:1564-1571.
15. International Agency for Research on Cancer Working Group. 1985. Betelquid and areca-nut chewing. IARC (Int. Agency Res. Cancer) Monogr. Eval. Carcinog. Risk Chem. Hum. 37:137-202.
16. Khanna, R., S. R. Burrows, and D. J. Moss. 1995. Immune regulation in Epstein-Barr virus-associated diseases. Microbiol. Rev. 59:387-405.
17. Moss, D. J., I. S. Misko, S. R. Burrows, K. Burman, R. McCarthy, and T. B. Sculley. 1988. Cytotoxic T-cell clones discriminate between A- and B-type Epstein-Barr virus transformants. Nature (London) 331:719-721.
18. Rickinson, A. B., M. Rowe, I. J. Hart, Q. Y. Yao, L. E. Henderson, H. Rabin, and M. A. Epstein. 1984. T-cell-mediated regression of "spontaneous" and of Epstein-Barr virus-induced B-cell transformation in vitro: studies with cyclosporin A. Cell. Immunol. 87:646-658.
19. Rowe, D., L. Heston, J. Metlay, and G. Miller. 1985. Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1. Proc. Natl. Acad. Sci. USA 82:7429-7433.
20. Sample, J., L. Young, B. Martin, T. Chatman, E. Kieff, and A. B. Rickinson. 1990. Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes. J. Virol. 64:4084-4092.
21. Sculley, T. B., A. Apolloni, L. Hurren, D. J. Moss, D. A. Cooper. 1990. Co-infection with A- and B-type Epstein-Barr virus in human immunodeficiency virus-positive subjects. J. Infect. Dis. 162:643-648.
22. Serjeantson, S. W., and A. V. S. Hill. 1989. The colonization of the Pacific: the genetic evidence, p. 286-294. In A. V. S. Hill and S. W. Serjeantson (ed.), The colonization of the Pacific: a genetic trail. Clarendon Press, Oxford.
23. Sixbey, J. W., P. Shirley, P. J. Chesney, D. M. Buntin, and L. Resnick. 1989. Detection of a second widespread strain of Epstein-Barr virus. Lancet ii: 761-765.
24. Sixbey, J. W., P. Shirley, M. Sloas, N. Raab-Traub, and V. Israele. 1991. A transformation-incompetent, nuclear antigen 2-deleted Epstein-Barr virus associated with replicative infection. J. Infect. Dis. 163:1008-1015.
25. Skare, J., J. Farley, J. L. Strominger, K. O. Fresen, M. S. Cho, and H. zur Hausen. 1985. Transformation by Epstein-Barr virus requires DNA sequences in the region of BamHI fragments Y and H. J. Virol. 55:286-297.
26. Walling, D. M., S. N. Edmistan, J. W. Sixbey, M. Abdel-Hamid, L. Resnick, and N. Raab-Traub. 1992. Co-infection of multiple strains of the Epstein-Barr virus in human immunodeficiency virus-associated hairy leukoplakia. Proc. Natl. Acad. Sci. USA 89:6560-6564.
27. Walling, D. M., A. G. Perkins, J. Webster-Cyriaque, L. Resnick, and N. Raab-Traub. 1994. The Epstein-Barr virus EBNA-2 gene in oral hairy leukoplakia: strain variation, genetic recombination, and transcriptional expression. J. Virol. 68:7918-7926.
28. Walling, D. M., and N. Raab-Traub. 1994. Epstein-Barr virus intrastrain recombination in oral hairy leukoplakia. J. Virol. 68:7909-7917.
29. Yajima, V., B. Marczynska, and M. Nonoyama. 1978. Transforming activity of Epstein-Barr virus obtained by superinfection of Raji cells. Proc. Natl. Acad. Sci. USA 75:2008-2010.
30. Yao, Q. Y., M. Rowe, B. Martin, L. S. Young, and A. B. Rickinson. 1991. The Epstein-Barr virus carrier state: dominance of a single growth-transforming isolate in the blood and in the oropharynx of healthy virus carriers. J. Gen. Virol. 72:1579-1590.
31. Yao, Q. Y., R. J. Tierney, D. Croom-Carter, G. M. Cooper, C. J. Ellis, M. Rowe, and A. B. Rickinson. Isolation of intertypic recombinants of Epstein-Barr virus from T cell-immunocompromised individuals. J. Virol., in press.
32. Young, L. S., Q. Y. Yao, C. M. Rooney, T. B. Sculley, D. J. Moss, H. Rupani, G. Laux, G. W. Bornkamm, and A. B. Rickinson. 1987. New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and from normal individuals in endemic areas. J. Gen. Virol. 68:2853-2862.
33. Zimber, U., H. K. Adldinger, G. M. Lenoir, M. Vuillaume, M. V. Knebel-Doeberitz, G. Laux, C. Desgranges, P. Wittmann, U.-K. Freese, U. Schneider, and G. W. Bornkamm. 1986. Geographical prevalence of two types of Epstein-Barr virus. Virology 154:56-66.