Expression of defensin genes in A431 and M-HeLa cell lines and in tumors of human vulval and cervical carcinoma

Experimental Oncology

Volumn 23, Issue 2, 2001, Pages 119-122

  Lisovskiy, I L ^a   Soldatkina, M A ^a   Lytvyn, D I ^a   Markeeva, N V ^a   Turchak, O V ^b   Nespryad'ko, S V ^b   Vinnitskaya, A B ^b   Pogrebnoy, P V ^a  

^a R E KAVETSKY INSTITUTE OF EXPERIMENTAL PATHOLOGY   (Ukraine)

^b STATE INSTITUTION NATIONAL RESEARCH CENTER FOR RADIATION MEDICINE OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE   (Ukraine)

Author keywords

Cervix; Defensins; Epidermal growth factor; Expression; Tumor; Vulvae

Indexed keywords

EID: 0007885089     PISSN: 02043564     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Diamond G, Bevins CL. β-defensins: endogenous antibiotics of the innate host defense response. Clin Immunol Immunopathol 1998; 88: 221-5.
2. Ganz T. Defensins and host defense. Science 1999; 286: 420-1.
3. Boman HG. Gene-encoded peptide antibiotics and the concept of innate immunity: an update review. Scand J Immunol 1998; 48: 15-25.
4. Valore EV, Park CH, Quayle AJ, Wiles KR, McCray PB, Ganz T. Human β-defensin-1: an antimicrobial peptide of urogenital tissues. J Clin Invest 1998; 101: 1633-42.
5. Solomon D, Schiffman M, Tarone R. Comparison of three management strategies for patients with atypical squamous cells of undetermined significance: baseline results from a randomized trial. J Natl Cancer Inst 2001; 93: 293-9.
6. Hausen H. Cervical carcinoma and human papillomavirus: on the road to preventing a major human cancer. J Natl Cancer Inst 2001; 93: 252-3.
7. Hildelsheim A, Schiffman M, Bromley C, Wacholder S, Herrero R, Rodriquez A, Bratti M, Sherman M, Scarpiodis U, Lin Q-Q, Nerai M, Bromley R, Buetow K, Apple R, Burk R. Human papillomavirus type 16 variants and risk of cervical cancer. J Natl Cancer Inst 2001; 93: 315-8.
8. Pogrebnoy PV, Serov SM, Klenchin VA, Lukyanov AV, Garmanchuk LV, Tarnavsky DV, Markeeva NV, Bykorez AI. Expression of transforming growth factor type alpha gene transferred into A431 cells. Molec Biol 1993; 27: 833-8 (in Russian).
9. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-9.
10. Lisovskiy IL, Hobta AI, Soldatkina MA, Lytvyn DI, Markeeva NV, Sidorik LL, Pogrebnoy PV. The expression of defensin-6 (HD-6) in transformed human cell lines. Biopolymers Cell 2000; 6: 525-9 (in Russian).
11. Harder J, Bartels J, Christophers E, Schroder JM. A peptide antibiotic from human skin. Nature 1997; 387: 861.
12. Mizukawa N, Sawaki K, Yamashika E, Fukunaga J, Ueno T, Takagi S, Sugahara T. Presence of human beta-defensin-2 in oral squamous cell carcinoma. Anticancer Res 2000; 20: 2005-7.
13. Abiko Y, Mitamura J, Nishimura M, Muramutsu T, Inoue T, Shimono M, Kaku T. Pattern of expression of beta-defensins in oral squamous cell carcinoma. Cancer Lett 1999; 143: 37-43.
14. Tahara E. Molecular mechanism of human stomach carcinogenesis implicated in Helicobacter pilori infection. Exp Toxicol Pathol 1998; 50: 375-8.
15. McKaig RG, Baric RS, Olshan AF. Human papillomavirus and head and neck cancer: epidemiology and molecular biology. Head Neck 1998; 20: 250-65.
16. Sasaki H, Ishizuka T, Muto M, Nezu M, Nakanishi Y, Inagaki H, Watanabe H, Terada M. Presence of Streptococcus anginosus DNA in esophageal cancer, dysplasia of esophagus and gastric cancer. Cancer Res 1998; 58: 2991-5.