N-arylation of sulfonamides on solid supports

Journal of Combinatorial Chemistry

Volumn 2, Issue 1, 2000, Pages 29-32

  Combs, Andrew P ^a   Rafalski, Maria ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001997073     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc9900394     Document Type: Article

References (19)

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15. Copper salts could not be completely washed from the resin after the reaction, but they could be easily resin-quenched from the cleaved material using Chelex resin and the product filtered off. Although polystyrene resin was used for all the syntheses described, we later found that the copper salts were more easily washed away from PEG resins. The N-arylation yields were similar for PEG and PS resins.
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19. Vojkovsky, T. Detection of Secondary Amines on Solid Phase. Pept. Res. 1995, 8, 236-237.