-
1
-
-
0001921207
-
Neuropsycho-logical features of memory disorders
-
Terry RD, Katzman R, Bick KL (Eds.), Raven Press, New York, USA
-
BONDI MW, SALMON DP, BUTTERS NM: Neuropsycho-logical features of memory disorders. In: Alzheimer's Disease. Terry RD, Katzman R, Bick KL (Eds.), Raven Press, New York, USA (1993): 41 – 64.
-
(1993)
In: Alzheimer's Disease.
, pp. 41-64
-
-
BONDI, M.W.1
SALMON, D.P.2
BUTTERS, N.M.3
-
2
-
-
0028267440
-
Normal and abnormal biology of the I3-am-yloid precursor protein
-
Cowan WM (Ed.)
-
SELKOE DJ: Normal and abnormal biology of the I3-am-yloid precursor protein. Ann. Rev. Neurosci. Cowan WM (Ed.) (1994): 489 – 518.
-
(1994)
Ann. Rev. Neurosci.
, pp. 489-518
-
-
SELKOE, D.J.1
-
3
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimer's disease
-
YANKNER BA: Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron (1996) 16 (5): 921 – 932.
-
(1996)
Neuron
, vol.16
, Issue.5
, pp. 921-932
-
-
YANKNER, B.A.1
-
4
-
-
0027420369
-
Tau protein and the neuroflbrillary pa-thology of Alzheimer's disease
-
GOEDERT M: Tau protein and the neuroflbrillary pa-thology of Alzheimer's disease. Trends Neurosci. (1993) 16 (10460 – 465.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 10460-10465
-
-
GOEDERT, M.1
-
5
-
-
0029875437
-
Immune mechanisms in neu-rodegenerative disorders
-
MCGEER PL, MCGEER EG: Immune mechanisms in neu-rodegenerative disorders. Drugs Today (1996) 32: 149 – 158.
-
(1996)
Drugs Today
, vol.32
, pp. 149-158
-
-
MCGEER, P.L.1
MCGEER, E.G.2
-
6
-
-
0029879704
-
Neuroinflammatory mecha-nisms in Alzheimer's disease: opportunities of drug discoveries
-
COCHRAN FR, VITEK MP: Neuroinflammatory mecha-nisms in Alzheimer's disease: opportunities of drug discoveries. Exp. Opin. Invest. Drugs (1996) 5: 449 – 455.
-
(1996)
Exp. Opin. Invest. Drugs
, vol.5
, pp. 449-455
-
-
COCHRAN, F.R.1
VITEK, M.P.2
-
7
-
-
0026447529
-
Complement activation by I3-amyloid in Alzheimer's disease
-
ROGERS J, COOPER NR, WEBSTER S et al.: Complement activation by I3-amyloid in Alzheimer's disease. Proc. Natl Acad. ScL USA (1992) 89: 10016 – 10020.
-
(1992)
Proc. Natl Acad. ScL USA
, vol.89
, pp. 10016-10020
-
-
ROGERS, J.1
COOPER, N.R.2
WEBSTER, S.3
-
8
-
-
0030483709
-
Neurochemical studies of Alzheimer's dis- ease
-
PALMER AM: Neurochemical studies of Alzheimer's dis- ease. Neurodegeneration (1996) 5: 381 – 391.
-
(1996)
Neurodegeneration
, vol.5
, pp. 381-391
-
-
PALMER, A.M.1
-
9
-
-
0019972810
-
The cho-linergic hypothesis of geriatric memory dysfunction
-
BARTUS RT, DEAN RL, III., BEER B, LIPPA AS: The cho-linergic hypothesis of geriatric memory dysfunction. Science (1982) 217: 408 – 417.
-
(1982)
Science
, vol.217
, pp. 408-417
-
-
BARTUS, R.T.1
DEAN, R.L.2
BEER, B.3
LIPPA, A.S.4
-
10
-
-
0021962590
-
Loss of M2 muscar-inic receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation
-
MASH DC, FLYNN DD, POTTER LT: Loss of M2 muscar-inic receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation. Science (1985) 228: 1115 – 1157.
-
(1985)
Science
, vol.228
, pp. 1115-1157
-
-
MASH, D.C.1
FLYNN, D.D.2
POTTER, L.T.3
-
11
-
-
0025607117
-
Nicotinicacetylcholine receptor subtytpes in human frontal cortex: changes in Alzheimer's disease
-
SUGAYA K, GIACOBINI E, CHIAPPINELLI VA: Nicotinicacetylcholine receptor subtytpes in human frontal cortex: changes in Alzheimer's disease. J. Neurosci. Res. (1990) 27: 349 – 359.
-
(1990)
J. Neurosci. Res.
, vol.27
, pp. 349-359
-
-
SUGAYA, K.1
GIACOBINI, E.2
CHIAPPINELLI, V.A.3
-
12
-
-
0023516670
-
Nicotinic and muscariniccholinergic receptors in Alzheimer's disease and re-lated disorders
-
WHITEHOUSE PJ, KELLAR KJ: Nicotinic and muscariniccholinergic receptors in Alzheimer's disease and re-lated disorders. J. Neural Transm. Suppl. (1987) 24: 175 – 182.
-
(1987)
J. Neural Transm. Suppl.
, vol.24
, pp. 175-182
-
-
WHITEHOUSE, P.J.1
KELLAR, K.J.2
-
13
-
-
0025989976
-
Coupling of M1 muscarinic re-ceptors to G-proteins in Alzheimer's disease
-
PEARCE B, POTTER LT: Coupling of M1 muscarinic re-ceptors to G-proteins in Alzheimer's disease. Alz. Dis. Assoc. Disord. (1991) 5: 163 – 172.
-
(1991)
Alz. Dis. Assoc. Disord.
, vol.5
, pp. 163-172
-
-
PEARCE, B.1
POTTER, L.T.2
-
14
-
-
0038272048
-
Central cholinergic systems, cholinergic drugs and Alzheimer's disease - an overview
-
DEFEUDIS FV: Central cholinergic systems, cholinergic drugs and Alzheimer's disease - an overview. Drugs To-day (1988) 24 (7): 473 – 490.
-
(1988)
Drugs To-day
, vol.24
, Issue.7
, pp. 473-490
-
-
DEFEUDIS, F.V.1
-
15
-
-
13544273898
-
The cholinergic hypothesis of dementia
-
IVERSON LL: The cholinergic hypothesis of dementia. Trends Pharm. Sci. (1986) (Suppl.): 44 – 45.
-
(1986)
Trends Pharm. Sci.
, pp. 44-45
-
-
IVERSON, L.L.1
-
16
-
-
0018078940
-
Correlationof cholinergic abnormalities with senile plaques and mental test scores in senile dementia
-
PERRY EK, TOMLINSON BE, BLESSED G et al: Correlationof cholinergic abnormalities with senile plaques and mental test scores in senile dementia. Br. Med. J. (1978) 2: 1457 – 1459.
-
(1978)
Br. Med. J.
, vol.2
, pp. 1457-1459
-
-
PERRY, E.K.1
TOMLINSON, B.E.2
BLESSED, G.3
-
17
-
-
0022645755
-
The cholinergic hypothesis - ten years on
-
PERRY EK: The cholinergic hypothesis - ten years on. Br. Med. Bull. (1986) 42 (1): 63 – 69.
-
(1986)
Br. Med. Bull.
, vol.42
, Issue.1
, pp. 63-69
-
-
PERRY, E.K.1
-
18
-
-
0020686674
-
Alzheimer's disease: a disorder of cortical cholinergic innervation
-
COYLE JT, PRICE DL, DELONG MR: Alzheimer's disease: a disorder of cortical cholinergic innervation. Science (1983) 219: 1184 – 1190.
-
(1983)
Science
, vol.219
, pp. 1184-1190
-
-
COYLE, J.T.1
PRICE, D.L.2
DELONG, M.R.3
-
19
-
-
0020072221
-
Alz-heimer's disease and senile dementia: loss of neurons in the basal forebrain
-
WHITEHOUSE PJ, PRICE DL, STRUBLE RG et al.: Alz-heimer's disease and senile dementia: loss of neurons in the basal forebrain. Science (1982) 215: 1237 – 1239.
-
(1982)
Science
, vol.215
, pp. 1237-1239
-
-
WHITEHOUSE, P.J.1
PRICE, D.L.2
STRUBLE, R.G.3
-
20
-
-
0030910311
-
Measurement of ace-tycholinesterase by positron emission tomography in the brains of healthy controls and patients with Alz-heimer's disease
-
IYO M, NAMBA H, FUKUSHI H et al: Measurement of ace-tycholinesterase by positron emission tomography in the brains of healthy controls and patients with Alz-heimer's disease. Lancet (1997) 349: 1805 – 1809.
-
(1997)
Lancet
, vol.349
, pp. 1805-1809
-
-
IYO, M.1
NAMBA, H.2
FUKUSHI, H.3
-
21
-
-
0027753043
-
Clinical studies in Alzheimer patients with positron emission tomography
-
NORDBERG A: Clinical studies in Alzheimer patients with positron emission tomography. Behav. Brain Res. (1993) 57: 215 – 224.
-
(1993)
Behav. Brain Res.
, vol.57
, pp. 215-224
-
-
NORDBERG, A.1
-
22
-
-
0029808280
-
In vivo map-ping of cholinergic terminals in normal aging, Alz-heimer's disease, and Parkinson's disease
-
KUHL DE, MINOSHIMA S, FESSLER JA et al: In vivo map-ping of cholinergic terminals in normal aging, Alz-heimer's disease, and Parkinson's disease. Ann. Neurol (1996) 40 (3): 399 – 410.
-
(1996)
Ann. Neurol
, vol.40
, Issue.3
, pp. 399-410
-
-
KUHL, D.E.1
MINOSHIMA, S.2
FESSLER, J.A.3
-
23
-
-
0022386340
-
Func- tional and neurochemical cortical cholinergic impair-ment following neurotoxic lesions of the nucleus basalis magnocellularis in the rat
-
EL-DEFRAWY SR, COLOMA F, JHAMANDAS K et al Func- tional and neurochemical cortical cholinergic impair-ment following neurotoxic lesions of the nucleus basalis magnocellularis in the rat. Neurobiol. Aging (1985) 6: 325 – 330.
-
(1985)
Neurobiol. Aging
, vol.6
, pp. 325-330
-
-
EL-DEFRAWY, S.R.1
COLOMA, F.2
JHAMANDAS, K.3
-
24
-
-
0021971588
-
Memory impairments following basal forebrain le-sions
-
HEPLER DJ, WENK GL, CRIBBS BL, OLTON DS, COYLE JT: Memory impairments following basal forebrain le-sions. Brain Res. (1985) 346: 8 – 14.
-
(1985)
Brain Res.
, vol.346
, pp. 8-14
-
-
HEPLER, D.J.1
WENK, G.L.2
CRIBBS, B.L.3
OLTON, D.S.4
COYLE, J.T.5
-
25
-
-
0022373859
-
YA-MAMURA HI: Effects of bilateral ibotenate-induced le-sions of the nucleus basalis magnocellularis upon selective cholinergic biochemical markers in the rat anterior cerebral cortex
-
WATSON M, VICKROY TW, FIBIGER HC, ROESKE WR, YA-MAMURA HI: Effects of bilateral ibotenate-induced le-sions of the nucleus basalis magnocellularis upon selective cholinergic biochemical markers in the rat anterior cerebral cortex. Brain Res. (1985) 346: 387 – 391.
-
(1985)
Brain Res.
, vol.346
, pp. 387-391
-
-
WATSON, M.1
VICKROY, T.W.2
FIBIGER, H.C.3
ROESKE, W.R.4
-
26
-
-
0018256391
-
Evidence for a direct cholinergic involve-ment in the scopolamine induced amnesia in mon-keys: effects of concurrent administration of physostigmine and methylphenidate with scopola-mine
-
BARTUS RT: Evidence for a direct cholinergic involve-ment in the scopolamine induced amnesia in mon-keys: effects of concurrent administration of physostigmine and methylphenidate with scopola-mine. Pharmacol. Biochem. Behav. (1978) 9(6) 833 – 836.
-
(1978)
Pharmacol. Biochem. Behav.
, vol.9
, Issue.6
, pp. 833-836
-
-
BARTUS, R.T.1
-
27
-
-
17344392330
-
Intracerebroventricular hemicholinium-3 (HC-3) impairs learning of a passive avoidance task in mice
-
CAULFIELD MP, FORTUNE DH, ROBERTS PM, STUBLEY JK: Intracerebroventricular hemicholinium-3 (HC-3) impairs learning of a passive avoidance task in mice. Br. J. Pharmacol (1981) 74: 865.
-
(1981)
Br. J. Pharmacol
, vol.74
, pp. 865
-
-
CAULFIELD, M.P.1
FORTUNE, D.H.2
ROBERTS, P.M.3
STUBLEY, J.K.4
-
28
-
-
0028270519
-
A 30-weekrandomized controlled trial of high dose tacrine in pa-tients with Alzheimer's disease
-
KNAPP MJ, KNOPMAN DS, SOLOMON PR etal: A 30-weekrandomized controlled trial of high dose tacrine in pa-tients with Alzheimer's disease. JAMA (1994) 271: 985 – 991.
-
(1994)
JAMA
, vol.271
, pp. 985-991
-
-
KNAPP, M.J.1
KNOPMAN, D.S.2
SOLOMON, P.R.3
-
29
-
-
0001854077
-
E2020 produces both clinical global and cognitive test im-provement in patients with mild to moderately severe Alzheimer's disease: results of a 30-week Phase III trial
-
ROGERS SL, DOODY R, MOHS R, FRIEDHOFF LT: E2020 produces both clinical global and cognitive test im-provement in patients with mild to moderately severe Alzheimer's disease: results of a 30-week Phase III trial. Neurology (1996) 46 (Suppl.): A217.
-
(1996)
Neurology
, vol.46
, pp. A217
-
-
ROGERS, S.L.1
DOODY, R.2
MOHS, R.3
FRIEDHOFF, L.T.4
-
31
-
-
0026620028
-
Tacrine re-stores cholinergic nicotinic and glucose metabolism in Alzheimer patients as visualized by positron emis-sion tomography
-
NORDBERG A, LILJA A, HARTVIG P et al.: Tacrine re-stores cholinergic nicotinic and glucose metabolism in Alzheimer patients as visualized by positron emis-sion tomography. Neurobiol. Aging (1992) 13: 747 – 758.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 747-758
-
-
NORDBERG, A.1
LILJA, A.2
HARTVIG, P.3
-
32
-
-
0029592066
-
Acetylcholine release enhancing agents: potential therapeutics for Alz-heimer's disease
-
CHORVAT RJ, EARL RA, ZACZEK R: Acetylcholine release enhancing agents: potential therapeutics for Alz-heimer's disease. Drugs Fut. (1995) 20: 1145 – 1162.
-
(1995)
Drugs Fut.
, vol.20
, pp. 1145-1162
-
-
CHORVAT, R.J.1
EARL, R.A.2
ZACZEK, R.3
-
33
-
-
0021284541
-
Release of acetylcholine from rat brain synaptosomes by various agents in the ab-sence of external calcium ions
-
ADAM-VIZI V, LIGETI E: Release of acetylcholine from rat brain synaptosomes by various agents in the ab-sence of external calcium ions. J. Physiol. (fond.) (1984) 353: 505 – 521.
-
(1984)
J. Physiol. (fond.)
, vol.353
, pp. 505-521
-
-
ADAM-VIZI, V.1
LIGETI, E.2
-
34
-
-
0018873513
-
Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes
-
CATTERALL WA: Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. Ann. Rev. Pharmacol. Toxicol. (1980) 20: 15 – 43.
-
(1980)
Ann. Rev. Pharmacol. Toxicol.
, vol.20
, pp. 15-43
-
-
CATTERALL, W.A.1
-
35
-
-
0025216441
-
DUP 996(3,3-bis (4-pyrindinylmethy0-1-phenylindolin-2-one enhances the stimulus-induced release of acetylcho-line from rat brain in vitro and in vivo
-
NICKOLSON VJ, TAM SW, MYERS MJ, COOK L: DUP 996(3,3-bis (4-pyrindinylmethy0-1-phenylindolin-2-one enhances the stimulus-induced release of acetylcho-line from rat brain in vitro and in vivo. Drug Dev. Res. (1990) 19: 285 – 300.
-
(1990)
Drug Dev. Res.
, vol.19
, pp. 285-300
-
-
NICKOLSON, V.J.1
TAM, S.W.2
MYERS, M.J.3
COOK, L.4
-
36
-
-
0004287508
-
-
Robinson TE, Justice JJB (Ed.), Elsevier, Cam-bridge, UK
-
ROBINSON TE, JUSTICE JB: Microdialysis in the Neuro-sciences. Robinson TE, Justice JJB (Ed.), Elsevier, Cam-bridge, UK (1991).
-
(1991)
Microdialysis in the Neuro-sciences.
-
-
ROBINSON, T.E.1
JUSTICE, J.B.2
-
37
-
-
0030744573
-
The acetyl-choline releaser linopirdine increases parietal regional blood flow in Alzheimer's disease
-
VAN DYCK CH, LIN CH, ROBINSON R et al: The acetyl-choline releaser linopirdine increases parietal regional blood flow in Alzheimer's disease. Psycho-pharmacology (1997) 132: 217 – 226.
-
(1997)
Psycho-pharmacology
, vol.132
, pp. 217-226
-
-
VAN DYCK, C.H.1
LIN, C.H.2
ROBINSON, R.3
-
38
-
-
0001186564
-
Axo-somatic and axo-dexdritic synapses ofthe cerebral cortex: an electron microscope study
-
GRAY EG: Axo-somatic and axo-dexdritic synapses ofthe cerebral cortex: an electron microscope study. J. Anat. (1959) 93: 420 – 433.
-
(1959)
J. Anat.
, vol.93
, pp. 420-433
-
-
GRAY, E.G.1
-
39
-
-
0027489573
-
Cytoskeleton dynamics dur- ing neurotransmitter release
-
TRIFARO J-M, VITALE ML: Cytoskeleton dynamics dur- ing neurotransmitter release. Trends Neurosci. (1993) 16 (10466 – 472.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 10466-10472
-
-
TRIFARO, J.-M.1
VITALE, M.L.2
-
40
-
-
0026939128
-
The transport of neurotransmitters into synaptic vesicles
-
EDWARDS RH: The transport of neurotransmitters into synaptic vesicles. Curr. Opin. Neurobiol (1992) 2: 586 – 594.
-
(1992)
Curr. Opin. Neurobiol
, vol.2
, pp. 586-594
-
-
EDWARDS, R.H.1
-
41
-
-
0029863653
-
Monte Carlo simulation of fast excitatory synaptic transmission at at a hippocampal synapse
-
WAHL LM, POUZAT C, STRATFORD KJ: Monte Carlo simulation of fast excitatory synaptic transmission at at a hippocampal synapse. J. Neurophysiol. (1996) 75 (2): 597 – 608.
-
(1996)
J. Neurophysiol.
, vol.75
, Issue.2
, pp. 597-608
-
-
WAHL, L.M.1
POUZAT, C.2
STRATFORD, K.J.3
-
42
-
-
0029876527
-
Transmitter timecourse in the synaptic cleft: its role in central synaptic function
-
CLEMENS JD: Transmitter timecourse in the synaptic cleft: its role in central synaptic function. Trends Neuro-sci. (1996) 19 (5): 163 – 171.
-
(1996)
Trends Neuro-sci.
, vol.19
, Issue.5
, pp. 163-171
-
-
CLEMENS, J.D.1
-
43
-
-
0027338262
-
A low affinity Ca ++ recep-tor controls the final steps in peptide secretion from pituitary melanotrophs
-
THOMAS P, WONG JG, LEE AK: A low affinity Ca ++ recep-tor controls the final steps in peptide secretion from pituitary melanotrophs. Neuron (1993) 11: 93 – 104.
-
(1993)
Neuron
, vol.11
, pp. 93-104
-
-
THOMAS, P.1
WONG, J.G.2
LEE, A.K.3
-
44
-
-
0028950269
-
The biochemistry of neu-rotransmitter secretion
-
BAJJALIEH SM SCHELLER RH: The biochemistry of neu-rotransmitter secretion. J. Biol. Chem. (1995) 270: 1971 – 1974
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 1971-1974
-
-
BAJJALIEH, S.M.1
SCHELLER, R.H.2
-
46
-
-
0026399923
-
The calcium signal for transmitter secretion from presynaptic nerve terminals
-
AUGUSTINE GJ, ADLER EM, CHARLTON MP: The calcium signal for transmitter secretion from presynaptic nerve terminals. Ann. NY Acad. Sci. (1991) 635: 365 – 381.
-
(1991)
Ann. NY Acad. Sci.
, vol.635
, pp. 365-381
-
-
AUGUSTINE, G.J.1
ADLER, E.M.2
CHARLTON, M.P.3
-
47
-
-
0026600228
-
The synaptic vesicle protein synaptotagmin associates with calcium chan-nels and is a putative Lambert-Eaton myasthenic syn-drome antigen
-
LEVEQUE C, HOSHINO T, DAVID P: The synaptic vesicle protein synaptotagmin associates with calcium chan-nels and is a putative Lambert-Eaton myasthenic syn-drome antigen. Proc. NatL Acad. Sci. USA (1992) 89: 3625 – 3629.
-
(1992)
Proc. NatL Acad. Sci. USA
, vol.89
, pp. 3625-3629
-
-
LEVEQUE, C.1
HOSHINO, T.2
DAVID, P.3
-
48
-
-
0027127386
-
Neurotrans-mitter release from synaptotagmin-deficient clonal variants of PC12 cells
-
SHOJI-KASAI Y, YOSHIDA A, SATO K et al.: Neurotrans-mitter release from synaptotagmin-deficient clonal variants of PC12 cells. Science (1992) 256: 1820 - 1823.
-
(1992)
Science
, vol.256
, pp. 1820-1823
-
-
SHOJI-KASAI, Y.1
YOSHIDA, A.2
SATO, K.3
-
49
-
-
0027197065
-
Synaptogamin: a calcium sensitive inhibi-tor of exocytosis
-
POPOV SV: Synaptogamin: a calcium sensitive inhibi-tor of exocytosis. Cell (1993) 73: 1247 – 1249.
-
(1993)
Cell
, vol.73
, pp. 1247-1249
-
-
POPOV, S.V.1
-
50
-
-
85018867726
-
Models and mechanisms of neurotrans-mission
-
Powis DA, Bunn SJ (Eds.), Cambridge University Press, Cambridge, UK
-
BENNETT MR: Models and mechanisms of neurotrans-mission. In: Neurotransmitter Release and Its Modulation. Powis DA, Bunn SJ (Eds.), Cambridge University Press, Cambridge, UK (1995): 38 – 54.
-
(1995)
In: Neurotransmitter Release and Its Modulation.
, pp. 38-54
-
-
BENNETT, M.R.1
-
51
-
-
0018649657
-
Estimates of the quantal content dur-ing 'chemical potentiation' of transmitter release
-
KATZ B, MILEDI R: Estimates of the quantal content dur-ing 'chemical potentiation' of transmitter release. Proc. Royal. Soc. London, Series B (1979) 205: 369 – 378.
-
(1979)
Proc. Royal. Soc. London, Series B
, vol.205
, pp. 369-378
-
-
KATZ, B.1
MILEDI, R.2
-
52
-
-
0024472084
-
Multiplicity of GABAA-benzodiazepine receptors
-
SIEGHART W: Multiplicity of GABAA-benzodiazepine receptors. Trends Pharm. Sci. (1989) 10: 407 – 411.
-
(1989)
Trends Pharm. Sci.
, vol.10
, pp. 407-411
-
-
SIEGHART, W.1
-
53
-
-
0023824373
-
Electrophysiology of GABAA and GABAB receptor sybtypes
-
© Ashley Publications Ltd. All rights reserved.Exp. Opin. Invest. Drugs (1998) 7(4)
-
BORMANN J: Electrophysiology of GABAA and GABAB receptor sybtypes. Trends Neurosci. (1988) 11:112-116. © Ashley Publications Ltd. All rights reserved.Exp. Opin. Invest. Drugs (1998) 7(4)
-
(1988)
Trends Neurosci.
, vol.11
, pp. 112-116
-
-
BORMANN, J.1
-
54
-
-
0026615116
-
GABAA receptors: ligand-gated cr ion channels modulated by multiple drug-binding sites
-
SIEGHART W: GABAA receptors: ligand-gated cr ion channels modulated by multiple drug-binding sites. Trends Pharm. Sci. (1992) 13: 446 – 450.
-
(1992)
Trends Pharm. Sci.
, vol.13
, pp. 446-450
-
-
SIEGHART, W.1
-
55
-
-
0018905056
-
Modulation by GABA of cholinergic transmission in the striatum
-
SCATTON B, BARTHOLINI G: Modulation by GABA of cholinergic transmission in the striatum. Brain Res. (1980) 183: 211 – 216.
-
(1980)
Brain Res.
, vol.183
, pp. 211-216
-
-
SCATTON, B.1
BARTHOLINI, G.2
-
56
-
-
0020052857
-
Gamma-aminobutyric acid (GABA) receptor stimulation. IV. Effect of proga-bide (SL 76002) and other GABAergic agents on acetyl-choline turnover in rat brain areas
-
SCATTON B, BARTHOLINI G: Gamma-aminobutyric acid (GABA) receptor stimulation. IV. Effect of proga-bide (SL 76002) and other GABAergic agents on acetyl-choline turnover in rat brain areas. J. Pharmacol Exp. Ther. (1982) 220: 689 – 695.
-
(1982)
J. Pharmacol Exp. Ther.
, vol.220
, pp. 689-695
-
-
SCATTON, B.1
BARTHOLINI, G.2
-
57
-
-
0018772110
-
GABA modu-lates the release of dopamine and acetylcholine from rat caudate nucleus slices
-
STOOF JC, DENBREEJEN EJS, MULDER AH: GABA modu-lates the release of dopamine and acetylcholine from rat caudate nucleus slices. Eur. J. Pharmacol (1979) 57: 35 – 42.
-
(1979)
Eur. J. Pharmacol
, vol.57
, pp. 35-42
-
-
STOOF JC, D.E.1
MULDER, A.H.2
-
58
-
-
0021955763
-
Modulation of acetylcho-line release from rat striatal slices by the GABA/benzo-diazepine receptor complex
-
SUPAVILAI P, KAROBATH M: Modulation of acetylcho-line release from rat striatal slices by the GABA/benzo-diazepine receptor complex. Life Sci. (1985) 36: 417 – 426.
-
(1985)
Life Sci.
, vol.36
, pp. 417-426
-
-
SUPAVILAI, P.1
KAROBATH, M.2
-
59
-
-
0027330154
-
GABAA and GABAB receptors differentially regulate striatal acetylcholine release in vivo
-
ANDERSON JJ, KUO S, CHASE TN, ENGBER TM: GABAA and GABAB receptors differentially regulate striatal acetylcholine release in vivo. NeuroscI Letts. (1993) 160: 126 – 130.
-
(1993)
NeuroscI Letts.
, vol.160
, pp. 126-130
-
-
ANDERSON, J.J.1
KUO, S.2
CHASE, T.N.3
ENGBER, T.M.4
-
60
-
-
70350717296
-
Benzodiazepine impairs and I3-carboline en-hances performance in learning and memory tasks
-
VENAULT P, CHAPOUTHIER G, PRADO DE CARVALHO L et al Benzodiazepine impairs and I3-carboline en-hances performance in learning and memory tasks. Nature (1986) 321 – 864.
-
(1986)
Nature
, pp. 321-864
-
-
VENAULT, P.1
CHAPOUTHIER, G.2
PRADO DE, C.L.3
-
62
-
-
0023092123
-
Pro-tection against the lethal effects of pentobarbital in mice by a benzodiazepine receptor inverse agonist, 6,7-dimethoxy-4-ethyl-3-carbmethoxy-b-carboline
-
HAVOUNDJIAN H, REED GF, PAUL SM, SKOLNICK P: Pro-tection against the lethal effects of pentobarbital in mice by a benzodiazepine receptor inverse agonist, 6,7-dimethoxy-4-ethyl-3-carbmethoxy-b-carboline. J. Clin. Invest. (1987) 79: 473 – 477.
-
(1987)
J. Clin. Invest.
, vol.79
, pp. 473-477
-
-
HAVOUNDJIAN, H.1
REED, G.F.2
PAUL, S.M.3
SKOLNICK, P.4
-
63
-
-
0019996866
-
PE-TERSEN EN: Interaction of convulsive ligands with ben-zodiazepine receptors
-
BRAESTRUP C, SCHMIECHEN R, NEEF G, NIELSEN M, PE-TERSEN EN: Interaction of convulsive ligands with ben-zodiazepine receptors. Science (1982) 216: 1241 – 1243.
-
(1982)
Science
, vol.216
, pp. 1241-1243
-
-
BRAESTRUP, C.1
SCHMIECHEN, R.2
NEEF, G.3
NIELSEN, M.4
-
64
-
-
85018935016
-
Cognition enhancement medi-ated via transsynaptic, behavior-dependent stimula-tion of cortical acetylcholine release
-
SARTER M, BRUNO JP: Cognition enhancement medi-ated via transsynaptic, behavior-dependent stimula-tion of cortical acetylcholine release. Neuropsychopharmacology (1994) 10(3S/Part 1): S65 – 282.
-
(1994)
Neuropsychopharmacology
, vol.10
, Issue.3S/Part 1
, pp. S65-282
-
-
SARTER, M.1
BRUNO, J.P.2
-
65
-
-
0027458144
-
Bidirectional modula-tion of stimulated cortical acetylcholine release by benzodiazepine receptor ligands
-
MOORE H, SARTER M, BRUNO JP: Bidirectional modula-tion of stimulated cortical acetylcholine release by benzodiazepine receptor ligands. Brain Res. (1993) 627: 267 – 274.
-
(1993)
Brain Res.
, vol.627
, pp. 267-274
-
-
MOORE, H.1
SARTER, M.2
BRUNO, J.P.3
-
66
-
-
0026452292
-
Age-dependent modula-tion of in vivo cortical acetylcholine release by benzo-diazepine receptor ligands
-
MOORE H, SARTER M, BRUNO J: Age-dependent modula-tion of in vivo cortical acetylcholine release by benzo-diazepine receptor ligands. Brain Res. (1992) 596: 17 – 29.
-
(1992)
Brain Res.
, vol.596
, pp. 17-29
-
-
MOORE, H.1
SARTER, M.2
BRUNO, J.3
-
67
-
-
0028977859
-
Effects of ZK 93426, a beta-carboline benzodiazepine receptor antagonist on night sleep patterns in healthy male volunteers
-
DUKA T, GOERKE D, FICHTE K: Effects of ZK 93426, a beta-carboline benzodiazepine receptor antagonist on night sleep patterns in healthy male volunteers. Psy-chopharmacology (Berl.) (1995) 117 (2): 178 – 185.
-
(1995)
Psy-chopharmacology (Berl.)
, vol.117
, Issue.2
, pp. 178-185
-
-
DUKA, T.1
GOERKE, D.2
FICHTE, K.3
-
68
-
-
0028046692
-
Basal fore-brain injections of the benzodiazephine partial in-verse agonist FG 7142 enhance memory of rats in the double Y-maze
-
SMITH CG, BENINGER RJ, RICHARD J et al.: Basal fore-brain injections of the benzodiazephine partial in-verse agonist FG 7142 enhance memory of rats in the double Y-maze. Brain Res. (1994) 655 (1): 61 – 67.
-
(1994)
Brain Res.
, vol.655
, Issue.1
, pp. 61-67
-
-
SMITH, C.G.1
BENINGER, R.J.2
RICHARD, J.3
-
69
-
-
0028225557
-
The benzodiazepine receptor antagonist flumazenil increases acetylcholine release in rat hippocampus
-
IMPERATO A, DAZZI L, OBINU MC, GESSA LG, BIGGIO G: The benzodiazepine receptor antagonist flumazenil increases acetylcholine release in rat hippocampus. Brain Res. (1994) 647: 167 – 171.
-
(1994)
Brain Res.
, vol.647
, pp. 167-171
-
-
IMPERATO, A.1
DAZZI, L.2
OBINU, M.C.3
GESSA, L.G.4
BIGGIO, G.5
-
70
-
-
0029802676
-
Cognitive ef-fects of flumazenil in patients with Alzheimer's dis-ease
-
OTT BR, THOMPSON JA, WHELIHAN WM: Cognitive ef-fects of flumazenil in patients with Alzheimer's dis-ease. J. Clin. Psychopharmacol (1996) 16(5) 400 – 402.
-
(1996)
J. Clin. Psychopharmacol
, vol.16
, Issue.5
, pp. 400-402
-
-
OTT, B.R.1
THOMPSON, J.A.2
WHELIHAN, W.M.3
-
71
-
-
0030297144
-
A novel benzo-diazepine inverse agonist, S-8510, as a cognitive en-hancer
-
KAWASAKI K, MASAMI E, MASATO I et al.: A novel benzo-diazepine inverse agonist, S-8510, as a cognitive en-hancer. Prog. Neuro-Psychopharmacol. Biol. Psychiat. (1996) 20: 1413 – 1425.
-
(1996)
Prog. Neuro-Psychopharmacol. Biol. Psychiat.
, vol.20
, pp. 1413-1425
-
-
KAWASAKI, K.1
MASAMI, E.2
MASATO, I.3
-
72
-
-
0029944298
-
Synthesis and structure-activirty relationships of fused imidazopyri-dines: a new series of benzodiazepine receptor ligands
-
TAKADA S, SASATANI T, CHOMEI N et al: Synthesis and structure-activirty relationships of fused imidazopyri-dines: a new series of benzodiazepine receptor ligands. J Med. Chem. (1996) 39: 2844 – 2851.
-
(1996)
J Med. Chem.
, vol.39
, pp. 2844-2851
-
-
TAKADA, S.1
SASATANI, T.2
CHOMEI, N.3
-
73
-
-
85018908308
-
The nicotinic acetylcholine receptor
-
Hammond C (Ed.), Academic Press, San Diego, CA, USA
-
HAMMOND C: The nicotinic acetylcholine receptor. In: Cellular and Molecular Neurobiology. Hammond C (Ed.), Academic Press, San Diego, CA, USA (1996): 214 – 247.
-
(1996)
In: Cellular and Molecular Neurobiology.
, pp. 214-247
-
-
HAMMOND, C.1
-
74
-
-
0030175612
-
Nicotinic receptors in the develop-ment and modulation of CNS synapses
-
ROLE LW, BERG DK: Nicotinic receptors in the develop-ment and modulation of CNS synapses. Neuron (1996) 16: 1077 – 1085.
-
(1996)
Neuron
, vol.16
, pp. 1077-1085
-
-
ROLE, L.W.1
BERG, D.K.2
-
75
-
-
0029800519
-
Pharmacological characterization of a nicotinic auto-receptor in rat hippocampal synaptosomes
-
WILKIE GI, HUTSON P, SULLIVAN JP, WONNACOTT S: Pharmacological characterization of a nicotinic auto-receptor in rat hippocampal synaptosomes. Neuro-chem. Res. (1996) 21 (9): 1141 – 1148.
-
(1996)
Neuro-chem. Res.
, vol.21
, Issue.9
, pp. 1141-1148
-
-
WILKIE, G.I.1
HUTSON, P.2
SULLIVAN, J.P.3
WONNACOTT, S.4
-
76
-
-
0030047768
-
Cholinergic channel modulators as a novel therapeutic strategy for Alzheimer's disease
-
ARNERIC SP, HOLLADAY MW, SULLIVAN JP: Cholinergic channel modulators as a novel therapeutic strategy for Alzheimer's disease. Exp. Opin. Invest. Drugs (1996) 5: 79 – 100
-
(1996)
Exp. Opin. Invest. Drugs
, vol.5
, pp. 79-100
-
-
ARNERIC, S.P.1
HOLLADAY, M.W.2
SULLIVAN, J.P.3
-
77
-
-
0001237770
-
CNS nicotinic receptors: possible therapeutic targets in neurodegenerative disorders
-
COURT JA, PERRY EK: CNS nicotinic receptors: possible therapeutic targets in neurodegenerative disorders. CNS Drugs (1994) 2: 216 – 233.
-
(1994)
CNS Drugs
, vol.2
, pp. 216-233
-
-
COURT, J.A.1
PERRY, E.K.2
-
78
-
-
0026593533
-
KEL-LAR KJ: A subtype of nicotinic cholinergic receptor in rat brain is composed of a4 and 132 subunits and is up-regulated by chronic nicotine treatment
-
FLORES CM, ROGERS SW, PABREZA LA, WOLFE BB, KEL-LAR KJ: A subtype of nicotinic cholinergic receptor in rat brain is composed of a4 and 132 subunits and is up-regulated by chronic nicotine treatment. Mol. Pharm. (1992) 41: 31 – 37.
-
(1992)
Mol. Pharm.
, vol.41
, pp. 31-37
-
-
FLORES, C.M.1
ROGERS, S.W.2
PABREZA, L.A.3
WOLFE, B.B.4
-
79
-
-
0022350728
-
Autoradiographic localization of putative nicotinic receptors in the rat brain using [125I]-neuronal bungarotoxin
-
CLARKE PBS, PERT A: Autoradiographic localization of putative nicotinic receptors in the rat brain using [125I]-neuronal bungarotoxin. Brain Res. (1985) 348: 355 – 358.
-
(1985)
Brain Res
, vol.348
, pp. 355-358
-
-
CLARKE, P.B.S.1
PERT, A.2
-
80
-
-
0027518923
-
Molecular cloning, functional properties, and distribution of rat brain a7: a nicotinic cation channel highly permeable to calcium
-
SHIGUELA P, WADICHE J, DINELEY-MILLER K, DANI JA, PATRICK JW: Molecular cloning, functional properties, and distribution of rat brain a7: a nicotinic cation channel highly permeable to calcium. J. Neurosci. (1993) 13: 596 – 604.
-
(1993)
J. Neurosci.
, vol.13
, pp. 596-604
-
-
SHIGUELA, P.1
WADICHE, J.2
DINELEY-MILLER, K.3
DANI, J.A.4
PATRICK, J.W.5
-
81
-
-
0028194977
-
Cytoprotective actions of 2,4-dimethylbenzylidene anabasine in dif-ferentiated PC12 cells and septal cholinergic neurons
-
MARTIN EJ, PANICKER KS, KING MA etal: Cytoprotective actions of 2,4-dimethylbenzylidene anabasine in dif-ferentiated PC12 cells and septal cholinergic neurons. Drug Dev. Res. (1994) 13: 131 – 141.
-
(1994)
Drug Dev. Res.
, vol.13
, pp. 131-141
-
-
MARTIN, E.J.1
PANICKER, K.S.2
KING, M.A.3
-
82
-
-
0028343246
-
(5)-3-methy1-5-(1methyl-2-pyrrolidinyl)isoxazole (ABT-418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: 1. In vitro charac-terization
-
© Ashley Publications Ltd. All rights reserved.Exp. Opin. Invest. Drugs (1998) 7(4)
-
ARNERIC SP, SULLIVAN JP, BRIGGS CA et al.:(5)-3-methy1-5-(1methyl-2-pyrrolidinyl)isoxazole (ABT-418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: 1. In vitro charac-terization. J. Pharmacol. Exp.Ther. (1994) 270:310-318. © Ashley Publications Ltd. All rights reserved.Exp. Opin. Invest. Drugs (1998) 7(4)
-
(1994)
J. Pharmacol. Exp.Ther.
, vol.270
, pp. 310-318
-
-
ARNERIC, S.P.1
SULLIVAN, J.P.2
BRIGGS, C.A.3
-
83
-
-
0028243316
-
(S)-3-Methyl-5-(1-methyl-2-pyrrolidiinyl)isoxazole (ABT-418): a novel cholinergic ligand with cognition-enhancing and amdolytic activities: ii in vivo charac-terization
-
DECKER MW, BRIONI JD, SULLIVAN JP et al.: (S)-3-Methyl-5-(1-methyl-2-pyrrolidiinyl)isoxazole (ABT-418): a novel cholinergic ligand with cognition-enhancing and amdolytic activities: ii. in vivo charac-terization. J. Pharmacol. Exp. Ther. (1994) 270 (1) 319 – 328.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, Issue.1
, pp. 319-328
-
-
DECKER, M.W.1
BRIONI, J.D.2
SULLIVAN, J.P.3
-
84
-
-
0029120195
-
Comparative pharmacology of nicotine and ABT-418, a new nico-tinic agonist
-
DAMAJ MI, CREASY KR, WELCH SP et al.: Comparative pharmacology of nicotine and ABT-418, a new nico-tinic agonist. Psychopharmacology (Berl.) (1995) 120(4) 483 – 490.
-
(1995)
Psychopharmacology (Berl.)
, vol.120
, Issue.4
, pp. 483-490
-
-
DAMAJ, M.I.1
CREASY, K.R.2
WELCH, S.P.3
-
85
-
-
0030981799
-
Im-provement in accuracy of delayed recall in aged and non-aged, mature monkeys after intramuscular or transdermal administration of the CNS nicotinic re-ceptor agonist ABT-418
-
PENDERGRAST MA, TERRY AV, Jr., JACKSON WJ et al: Im-provement in accuracy of delayed recall in aged and non-aged, mature monkeys after intramuscular or transdermal administration of the CNS nicotinic re-ceptor agonist ABT-418. Psychopharmacology (Berl.) (1997) 130 (3): 276 – 284.
-
(1997)
Psychopharmacology (Berl.)
, vol.130
, Issue.3
, pp. 276-284
-
-
PENDERGRAST, M.A.1
TERRY, A.V.2
JACKSON, W.J.3
-
86
-
-
0031003185
-
Functional characterization of the novel neuronal nicotinic ace-tylcholine receptor ligand GTS-21 in vitro and in vivo
-
BRIGGS CA, ANDERSON DJ, BRIONI JD et al.: Functional characterization of the novel neuronal nicotinic ace-tylcholine receptor ligand GTS-21 in vitro and in vivo. Pharmacol. Biochem. Behav. (1997) 57 (1-2): 231 – 241.
-
(1997)
Pharmacol. Biochem. Behav.
, vol.57
, Issue.1-2
, pp. 231-241
-
-
BRIGGS, C.A.1
ANDERSON, D.J.2
BRIONI, J.D.3
-
87
-
-
0030858491
-
Nicotinic agonist modulation of neurotransmitter levels in the rat fron-toparietal cortex
-
SUMMERS KL, KEM WR, GIACOBINI E: Nicotinic agonist modulation of neurotransmitter levels in the rat fron-toparietal cortex. Jpn.J. Pharmacol (1997) 74(2) 139 – 146.
-
(1997)
Jpn.J. Pharmacol
, vol.74
, Issue.2
, pp. 139-146
-
-
SUMMERS, K.L.1
KEM, W.R.2
GIACOBINI, E.3
-
88
-
-
0014078590
-
The timing of calcium action during neuromuscular transmission
-
KATZ B MILEDI R: The timing of calcium action during neuromuscular transmission. J. Physiol. (1967) 189: 535 – 544.
-
(1967)
J. Physiol.
, vol.189
, pp. 535-544
-
-
KATZ, B.1
MILEDI, R.2
-
90
-
-
0027105121
-
Presynaptic calcium concentration microdomains and transmitter release
-
LLINAS R, SUGIMORI M, SILVER RB: Presynaptic calcium concentration microdomains and transmitter release. Physiol. (1992) 86 (1-3): 135 – 138.
-
(1992)
Physiol.
, vol.86
, Issue.1-3
, pp. 135-138
-
-
LLINAS, R.1
SUGIMORI, M.2
SILVER, R.B.3
-
91
-
-
0002518650
-
Transmitter re-lease
-
Elsevier Science, New York, USA
-
KANDEL ER, SCHWARZ JH, JESSELL TM: Transmitter re-lease. In: Principles of Neural Science. Elsevier Science, New York, USA (1990: 194 – 212.
-
(1990)
In: Principles of Neural Science.
, pp. 194-212
-
-
KANDEL, E.R.1
SCHWARZ, J.H.2
JESSELL, T.M.3
-
92
-
-
0028985125
-
Exocytotic Ca2+ chan-nels in mammalian central neurons
-
DUNLAP K, LUEBKE JI, TURNER TJ: Exocytotic Ca2+ chan-nels in mammalian central neurons. Trends Neurosci. (1995) 18: 89 – 98
-
(1995)
Trends Neurosci
, vol.18
, pp. 89-98
-
-
DUNLAP, K.1
LUEBKE, J.I.2
TURNER, T.J.3
-
93
-
-
0021130271
-
Nootropic drugs: animal models for studying effects on cognition
-
SCHINDLER U, RUSH DK, FIELDING S: Nootropic drugs: animal models for studying effects on cognition. Drug Dev. Res. (1984) 4 (5): 567 – 76.
-
(1984)
Drug Dev. Res.
, vol.4
, Issue.5
, pp. 567-576
-
-
SCHINDLER, U.1
RUSH, D.K.2
FIELDING, S.3
-
94
-
-
0028224652
-
Piracetam and other struc-turally related nootropics
-
GOULIAEV AH, SENNING A: Piracetam and other struc-turally related nootropics. Brain Res. Rev. (1994) 19: 180 – 222.
-
(1994)
Brain Res. Rev.
, vol.19
, pp. 180-222
-
-
GOULIAEV, A.H.1
SENNING, A.2
-
95
-
-
0028207467
-
Effects of nefiracetam on drug-induced impairment of latent learning mice in a water finding task
-
NABESHIMA T, NAKAYAMA S, ICHIHARA K et al.: Effects of nefiracetam on drug-induced impairment of latent learning mice in a water finding task. Eur. J. Pharmacol (1994) 255: 57 – 65.
-
(1994)
Eur. J. Pharmacol
, vol.255
, pp. 57-65
-
-
NABESHIMA, T.1
NAKAYAMA, S.2
ICHIHARA, K.3
-
96
-
-
0024523079
-
Effects of N-(2,6-dimethylpheny1)-2-(2-oxo-1 - pyrrolidinyfiacetamide (DM-9384) on learning and memory in rats
-
SAKURAI T, OJIMA H, YAMASAKI T, KOJIMA H, AKASHI A: Effects of N-(2,6-dimethylpheny1)-2-(2-oxo-1 - pyrrolidinyfiacetamide (DM-9384) on learning and memory in rats. Jpn. J. Pharmacol (1989) 50 (1): 47 – 53.
-
(1989)
Jpn. J. Pharmacol
, vol.50
, Issue.1
, pp. 47-53
-
-
SAKURAI, T.1
OJIMA, H.2
YAMASAKI, T.3
KOJIMA, H.4
AKASHI, A.5
-
97
-
-
85018905250
-
Effects ofnefiracetam on impairment of attention in latent learning task in mice
-
NAKAYAMA S, ICHIHARA K, YAMADA K et al: Effects ofnefiracetam on impairment of attention in latent learning task in mice. Neuropsychopharmaology (1994) 10: 58 – 89.
-
(1994)
Neuropsychopharmaology
, vol.10
, pp. 58-89
-
-
NAKAYAMA, S.1
ICHIHARA, K.2
YAMADA, K.3
-
98
-
-
0024992731
-
YA-MASAKI T: Effect of DM-9384 on extracellular acetyl-choline in the rat frontal cortex measured with microdialysis
-
KAWAJIRI S, TANIGUCKI K, SAKURAI T, KOJIMA H, YA-MASAKI T: Effect of DM-9384 on extracellular acetyl-choline in the rat frontal cortex measured with microdialysis. Eur. j Pharmacol (1990) 183 (3): 928.
-
(1990)
Eur. j Pharmacol
, vol.183
, Issue.3
, pp. 928
-
-
KAWAJIRI, S.1
TANIGUCKI, K.2
SAKURAI, T.3
KOJIMA, H.4
-
99
-
-
0028173017
-
Ne-firacetam enhances acetylcholine outflow from the frontal cortex: in vivo microdialysis study in the rat
-
KAWAJIRI S, TANIGUCKI K, SAKURAI T, YAMASAKI T: Ne-firacetam enhances acetylcholine outflow from the frontal cortex: in vivo microdialysis study in the rat. J. Neural. Trans. (1994) 98: 15 – 22.
-
(1994)
J. Neural. Trans.
, vol.98
, pp. 15-22
-
-
KAWAJIRI, S.1
TANIGUCKI, K.2
SAKURAI, T.3
YAMASAKI, T.4
-
100
-
-
0000688093
-
Excitatory amino acid receptors: multiplicity and structural requirements for activation and block-ade
-
Wheal HV, Thomson AM (Eds.), Academic Press, London, UK
-
KROGSGAARD-LARSEN P, LUND M, JOERGENSEN S, BREHM L: Excitatory amino acid receptors: multiplicity and structural requirements for activation and block-ade. In: Excitatory Amino Acids and Synaptic Transmission. Wheal HV, Thomson AM (Eds.), Academic Press, London, UK (1990: 1 – 17.
-
(1990)
In: Excitatory Amino Acids and Synaptic Transmission.
, pp. 1-17
-
-
KROGSGAARD-LARSEN, P.1
LUND, M.2
JOERGENSEN, S.3
BREHM, L.4
-
101
-
-
0028297182
-
Enhancement of neuronal cal-cium channel currents by the nootropic agent, nefi-racetam (DM-9384), in NG108-15 cells
-
YOSHII M, WATABE S: Enhancement of neuronal cal-cium channel currents by the nootropic agent, nefi-racetam (DM-9384), in NG108-15 cells. Brain Res. (1994) 642: 123 – 131.
-
(1994)
Brain Res
, vol.642
, pp. 123-131
-
-
YOSHII, M.1
WATABE, S.2
-
102
-
-
0027744324
-
Single calcium channels and acetylcho-line release at a presynaptic nerve terminal
-
STANLEY EF: Single calcium channels and acetylcho-line release at a presynaptic nerve terminal. Neuron (1993) 11: 1007 – 1011.
-
(1993)
Neuron
, vol.11
, pp. 1007-1011
-
-
STANLEY, E.F.1
-
103
-
-
0029826626
-
Nefiracetam (new drug profile)
-
GOA KL, BENFIELD P: Nefiracetam (new drug profile). CNS Drugs (1996) 6 (4): 331 – 337.
-
(1996)
CNS Drugs
, vol.6
, Issue.4
, pp. 331-337
-
-
GOA, K.L.1
BENFIELD, P.2
-
104
-
-
85018932480
-
Ameliorating effects of nefiracetam (DM-9384) on brain dysfunction
-
NABESHIMA T: Ameliorating effects of nefiracetam (DM-9384) on brain dysfunction. Shinkei Seishin Yakuri (1994) 16 (5): 309 – 333.
-
(1994)
Shinkei Seishin Yakuri
, vol.16
, Issue.5
, pp. 309-333
-
-
NABESHIMA, T.1
-
105
-
-
0000167680
-
It channels in the central nervous sys-tem
-
Cook NS (Ed.), Ellis Horwood Limited, Chichester, UK
-
HALLIWELL JV: It channels in the central nervous sys-tem. In: Potassium Channels - Structure, Classification, Function and Therapeutic Potential. Cook NS (Ed.), Ellis Horwood Limited, Chichester, UK (1990): 348 – 381.
-
(1990)
In: Potassium Channels - Structure, Classification, Function and Therapeutic Potential.
, pp. 348-381
-
-
HALLIWELL, J.V.1
-
106
-
-
0024388960
-
Basic mechanism and local modulation of nerve impulse-induced secretion of neurotransmit-ters from individual sympathetic nerve varicosities
-
STJARNE L: Basic mechanism and local modulation of nerve impulse-induced secretion of neurotransmit-ters from individual sympathetic nerve varicosities. Rev. Physiol. Biochem. Pharmacol (1989) 112: 1 – 138.
-
(1989)
Rev. Physiol. Biochem. Pharmacol
, vol.112
, pp. 1-138
-
-
STJARNE, L.1
-
107
-
-
0025918548
-
It and Ca2+ channel blockers may enhance or depress sympa-thetic tramsmitter release via a Ca +-dependent mechanism 'upstream' of the release site
-
STJARNE L, STJARNE E, MSGHINA M, BAO JX: It and Ca2+ channel blockers may enhance or depress sympa-thetic tramsmitter release via a Ca +-dependent mechanism 'upstream' of the release site. Neuroscience (1991) 44: 673 – 692.
-
(1991)
Neuroscience
, vol.44
, pp. 673-692
-
-
STJARNE, L.1
STJARNE, E.2
MSGHINA, M.3
BAO, J.X.4
-
108
-
-
0023580340
-
Multiple potassium conductances at the mammalian motor nerve termi-nal
-
SAINT DA, QUASTEL DM, GUAN YY: Multiple potassium conductances at the mammalian motor nerve termi-nal. Pflugers Arch. (1987) 410 (4-5): 408 – 412.
-
(1987)
Pflugers Arch.
, vol.410
, Issue.4-5
, pp. 408-412
-
-
SAINT, D.A.1
QUASTEL, D.M.2
GUAN, Y.Y.3
-
109
-
-
0027943785
-
Studies on the role of KF, a- and Na+ ion permeabilities in the acetyl-choline release enhancing effects of linopirdine (DuP 996) in rat cerebral cortical slices
-
MACIAG CM, LOGUE AR, TINKER WJ et al.: Studies on the role of KF, a- and Na+ ion permeabilities in the acetyl-choline release enhancing effects of linopirdine (DuP 996) in rat cerebral cortical slices. J. Pharmacol Exp. Then. (1994) 271: 891 – 7.
-
(1994)
J. Pharmacol Exp. Then.
, vol.271
, pp. 891-897
-
-
MACIAG, C.M.1
LOGUE, A.R.2
TINKER, W.J.3
-
110
-
-
0021357235
-
Effects of 4-aminopyridine in elderly patients with Alz-heimer's disease
-
WEISSLING H, AGOSTON S, VAN DAM GBP et al.: Effects of 4-aminopyridine in elderly patients with Alz-heimer's disease. New Eng. J. Med. (1984) 310: 988 – 989.
-
(1984)
New Eng. J. Med.
, vol.310
, pp. 988-989
-
-
WEISSLING, H.1
AGOSTON, S.2
VAN DAM, G.B.P.3
-
111
-
-
0023859179
-
The pharmacology of potassium channels and their therapeutic potential
-
COOK NS: The pharmacology of potassium channels and their therapeutic potential. Trends Pharmacol. Sci. (1988) 9: 21 – 28.
-
(1988)
Trends Pharmacol. Sci.
, vol.9
, pp. 21-28
-
-
COOK, N.S.1
-
112
-
-
0018866737
-
Facilitatory effects of 4-aminopyridine on normal neuromuscular trans-mission
-
© Ashley Publications Ltd. All rights reserved.Exp. Opin. Invest. Drugs (1998) 7(4)
-
KIM YI, GOLDNER MM, SANDERS DB: Facilitatory effects of 4-aminopyridine on normal neuromuscular trans-mission. Muscle Nerve (1980) 3:105-111. © Ashley Publications Ltd. All rights reserved.Exp. Opin. Invest. Drugs (1998) 7(4)
-
(1980)
Muscle Nerve
, vol.3
, pp. 105-111
-
-
KIM, Y.I.1
GOLDNER, M.M.2
SANDERS, D.B.3
-
113
-
-
0017662116
-
Effects of 4-aminopyridine on transmission in excita-tory and inhibitory synapses in the spinal cord
-
JANKOWSKA E, LUNDBERG A, RUDOMIN P, SYKOVA E: Effects of 4-aminopyridine on transmission in excita-tory and inhibitory synapses in the spinal cord. Brain Res. (1977) 136: 387 – 392.
-
(1977)
Brain Res
, vol.136
, pp. 387-392
-
-
JANKOWSKA, E.1
LUNDBERG, A.2
RUDOMIN, P.3
SYKOVA, E.4
-
114
-
-
0021369656
-
Effects of several aminopyri-dines and analogs on the calcium dependence of syn-aptic transmission
-
MITSUHIKO M, RIKER WK: Effects of several aminopyri-dines and analogs on the calcium dependence of syn-aptic transmission. J. Pharmacol. Exp. Ther. (1984) 228: 573 – 578.
-
(1984)
J. Pharmacol. Exp. Ther.
, vol.228
, pp. 573-578
-
-
MITSUHIKO, M.1
RIKER, W.K.2
-
116
-
-
77956779751
-
Neurotrans-mitter release enhancement as a possible therapy for neurodegenerative diseases: update on linopirdine (DUP996)
-
Giacobini E, Becker RE (Eds.), Birkhauser, Bos-ton, MA, USA
-
ZACZEK R, CHORVAT RJ, EARL RA, TAM SW: Neurotrans-mitter release enhancement as a possible therapy for neurodegenerative diseases: update on linopirdine (DUP996). In: Alzheimer's Disease: Therapeutic Ap-proaches. Giacobini E, Becker RE (Eds.), Birkhauser, Bos-ton, MA, USA (1990 252 – 255.
-
(1990)
In: Alzheimer's Disease: Therapeutic Ap-proaches.
, pp. 252-255
-
-
ZACZEK, R.1
CHORVAT, R.J.2
EARL, R.A.3
TAM, S.W.4
-
117
-
-
0024367939
-
3,4,-Diaminopyridine in the treatment of Lambert-Eaton myasthenic syndrome
-
MCEVOY KM, WINDEBANK AJ, DAUBE JR, LOW PA: 3,4,-Diaminopyridine in the treatment of Lambert-Eaton myasthenic syndrome. New Eng. J. Med. (1989) 23 (23): 1567 – 1571.
-
(1989)
New Eng. J. Med.
, vol.23
, Issue.23
, pp. 1567-1571
-
-
MCEVOY, K.M.1
WINDEBANK, A.J.2
DAUBE, J.R.3
LOW, P.A.4
-
118
-
-
0028101224
-
Tacrine increases stimulation-evoked acetylcholine release from rat hippocampal slices
-
SUZUKI T, NONAKA H, FUJIMOTO K, KAWASHIMA K: Tacrine increases stimulation-evoked acetylcholine release from rat hippocampal slices. Jpn. J. Pharmacol. (1994) 65: 337 – 342.
-
(1994)
Jpn. J. Pharmacol.
, vol.65
, pp. 337-342
-
-
SUZUKI, T.1
NONAKA, H.2
FUJIMOTO, K.3
KAWASHIMA, K.4
-
119
-
-
0026322494
-
NIK-247 blocks voltage-dependent ionic currents in crayfish axon
-
KOJIMA J, SUGAWARA Y, OBARA S: NIK-247 blocks voltage-dependent ionic currents in crayfish axon. Jpn Pharmacol. (1991) 57 (545 – 552).
-
(1991)
Jpn Pharmacol
, vol.57
, pp. 545-552
-
-
KOJIMA, J.1
SUGAWARA, Y.2
OBARA, S.3
-
120
-
-
0026515418
-
Evaluation of a cholinergic drug, 9-amino-2,3,5,6,7,8-hexahydro-1 H-cyclopenta-(b)-qu-inoline (NIK-247), as an enhancer of endogenous ef-flux of acetylcholine from brain slices
-
ISHII Y, SUMI T: Evaluation of a cholinergic drug, 9-amino-2,3,5,6,7,8-hexahydro-1 H-cyclopenta-(b)-qu-inoline (NIK-247), as an enhancer of endogenous ef-flux of acetylcholine from brain slices. Neuropharmacology (1992) 31: 61 – 66.
-
(1992)
Neuropharmacology
, vol.31
, pp. 61-66
-
-
ISHII, Y.1
SUMI, T.2
-
121
-
-
0028575329
-
Effect of NIK-247 on basal concentrations of extracellular ace-tycholine in the cerebral cortex of conscious, freely moving rats
-
ISHII Y, KOJIMA J, IKEDA N, KAWASHIMA K: Effect of NIK-247 on basal concentrations of extracellular ace-tycholine in the cerebral cortex of conscious, freely moving rats. Jpn. J. Pharmacol. (1994) 66: 289 – 293.
-
(1994)
Jpn. J. Pharmacol.
, vol.66
, pp. 289-293
-
-
ISHII, Y.1
KOJIMA, J.2
IKEDA, N.3
KAWASHIMA, K.4
-
122
-
-
0030691841
-
Linopirdine: phar-macology of a neurotransmitter release enhancer
-
ZACZEK R, CHORVAT RJ, BROWN BS: Linopirdine: phar-macology of a neurotransmitter release enhancer. CNS Drug Rev. (1997) 3 (2): 103 – 119.
-
(1997)
CNS Drug Rev.
, vol.3
, Issue.2
, pp. 103-119
-
-
ZACZEK, R.1
CHORVAT, R.J.2
BROWN, B.S.3
-
123
-
-
0027739616
-
Presynaptic cholinergic actions by the putative cognitive enhancing agent DuP 996
-
VICKROY TW: Presynaptic cholinergic actions by the putative cognitive enhancing agent DuP 996. J. Phar-macol. Exp. Ther. (1993) 264 (2): 910 – 917.
-
(1993)
J. Phar-macol. Exp. Ther.
, vol.264
, Issue.2
, pp. 910-917
-
-
VICKROY, T.W.1
-
124
-
-
85018886709
-
Effects of li-nopirdine (DuP 996) on KC1 and CaC12 dose response of potassium evoked release of NI acetylcholine from superfused hippocampal slices
-
TINKER WJ, MACIAG C, TAM SW, ZACZEK R: Effects of li-nopirdine (DuP 996) on KC1 and CaC12 dose response of potassium evoked release of NI acetylcholine from superfused hippocampal slices. Soc. Neurosci. Abstr. (1992) 18: 518 – 512.
-
(1992)
Soc. Neurosci. Abstr.
, vol.18
, pp. 512-518
-
-
TINKER, W.J.1
MACIAG, C.2
TAM, S.W.3
ZACZEK, R.4
-
125
-
-
26444583011
-
Electrophysiological effects of DuP 996 on hippocampal CA1 neurons
-
LAMPE BW, BROWN BS: Electrophysiological effects of DuP 996 on hippocampal CA1 neurons. Soc. Neurosci. Abstr. (1991) 17: 1588.
-
(1991)
Soc. Neurosci. Abstr.
, vol.17
, pp. 1588
-
-
LAMPE, B.W.1
BROWN, B.S.2
-
126
-
-
0029088690
-
Reduc-tion of spike frequency adaptation and blockade of M-current in rat CA1 pyramidal neurones by linopirdine (DuP 996), a neurotransmitter release enhancer
-
AIKEN SP, LAMPE BJ, MURPHY PA, BROWN BS: Reduc-tion of spike frequency adaptation and blockade of M-current in rat CA1 pyramidal neurones by linopirdine (DuP 996), a neurotransmitter release enhancer. Br. J. Pharmacol. (1995) 115: 1163 – 1168.
-
(1995)
Br. J. Pharmacol.
, vol.115
, pp. 1163-1168
-
-
AIKEN, S.P.1
LAMPE, B.J.2
MURPHY, P.A.3
BROWN, B.S.4
-
127
-
-
0031039651
-
Linopirdine reduces stimulus intensity threshold for induction of long-term potentiation in the Schaffer collateral/CA1 pathway in rat hippocampal slices
-
LAMPE BJ, GASKILL JL, KEIM SC, BROWN BS: Linopirdine reduces stimulus intensity threshold for induction of long-term potentiation in the Schaffer collateral/CA1 pathway in rat hippocampal slices. Neurosci. Letts. (1997) 222: 135 – 137.
-
(1997)
Neurosci. Letts.
, vol.222
, pp. 135-137
-
-
LAMPE, B.J.1
GASKILL, J.L.2
KEIM, S.C.3
BROWN, B.S.4
-
128
-
-
0025220350
-
Cognition enhancement by the acetyl-choline releaser DuP 996
-
COOK L, NICKOLSON VJ, STEINFELS GF, ROHRBACH KW, DENOBLE VJ: Cognition enhancement by the acetyl-choline releaser DuP 996. Drug Dev. Res. (1990) 19: 301 – 314.
-
(1990)
Drug Dev. Res.
, vol.19
, pp. 301-314
-
-
COOK, L.1
NICKOLSON, V.J.2
STEINFELS, G.F.3
ROHRBACH, K.W.4
DENOBLE, V.J.5
-
129
-
-
0002595981
-
Depolarization activated releas-ers of transmitters as therapeutics for dementia: pre-clinical characterization of linopirdine (DuP 996)
-
ZACZEK R, SAYDOFF J: Depolarization activated releas-ers of transmitters as therapeutics for dementia: pre-clinical characterization of linopirdine (DuP 996). Curr. Opin. Invest. Drugs (1993) 2 (10): 1097 – 1104.
-
(1993)
Curr. Opin. Invest. Drugs
, vol.2
, Issue.10
, pp. 1097-1104
-
-
ZACZEK, R.1
SAYDOFF, J.2
-
130
-
-
0025322605
-
Potassium currents in hippocampal pyrami-dal cells
-
Storm-Mathisen J, Zimmer J, Ottersen OP (Eds.), Elsevier, Amsterdam
-
STORM JF: Potassium currents in hippocampal pyrami-dal cells. In: Progress in Brain Research. Storm-Mathisen J, Zimmer J, Ottersen OP (Eds.), Elsevier, Amsterdam (1990 161 – 187.
-
(1990)
In: Progress in Brain Research.
, pp. 161-187
-
-
STORM, J.F.1
-
131
-
-
0018886033
-
Muscarinic suppression of a novel voltage-sensitive It current in a vertebrate neu-rone
-
BROWN DA, ADAMS PR: Muscarinic suppression of a novel voltage-sensitive It current in a vertebrate neu-rone. Nature (1980) 283: 673 – 676.
-
(1980)
Nature
, vol.283
, pp. 673-676
-
-
BROWN, D.A.1
ADAMS, P.R.2
-
132
-
-
0023899304
-
M-currents: an update
-
BROWN DA: M-currents: an update. Trends Neurosci. (1988) 11: 294 – 299.
-
(1988)
Trends Neurosci.
, vol.11
, pp. 294-299
-
-
BROWN, D.A.1
-
133
-
-
0029682660
-
Pharmacology of the neurotransmitter release enhancer linopirdine (DuP996), and insights into its mechanism of action
-
AIKEN SP, ZACZEK R, BROWN BS: Pharmacology of the neurotransmitter release enhancer linopirdine (DuP996), and insights into its mechanism of action. Adv. Pharmacol. (1996) 35: 349 – 384
-
(1996)
Adv. Pharmacol.
, vol.35
, pp. 349-384
-
-
AIKEN, S.P.1
ZACZEK, R.2
BROWN, B.S.3
-
134
-
-
0030959835
-
Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (Imm)) and some other voltage-and ligand-gates membrane currents in rat sympa-thetic neurons
-
LAMAS JA, SELYANKO AA, BROWN DA: Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (Imm)) and some other voltage-and ligand-gates membrane currents in rat sympa-thetic neurons. Eur. j Neurosci. (1997) 9: 605 – 616.
-
(1997)
Eur. j Neurosci.
, vol.9
, pp. 605-616
-
-
LAMAS, J.A.1
SELYANKO, A.A.2
BROWN, D.A.3
-
135
-
-
0028889856
-
Single-dose pharmacokinetics, safety, and tolerance of lino-pirdine (DuP 996) in healthy young adults and elderly volunteers
-
PIENIASZEK HJ, JR., FISKE WD, SAXTON TD et al.: Single-dose pharmacokinetics, safety, and tolerance of lino-pirdine (DuP 996) in healthy young adults and elderly volunteers. J. Clin. Pharmacol. (1995) 35 (1): 22 – 30.
-
(1995)
J. Clin. Pharmacol.
, vol.35
, Issue.1
, pp. 22-30
-
-
PIENIASZEK, H.J.1
FISKE, W.D.2
SAXTON, T.D.3
-
136
-
-
0025721918
-
EEG mapping cntral effects of multiple doses of linopirdine - a cogni-tive enhancer - in healthy elderly male subjects
-
SALETU B, DARRAGH A, BREUEL HP et al.: EEG mapping cntral effects of multiple doses of linopirdine - a cogni-tive enhancer - in healthy elderly male subjects. Hu-man PsychopharmacoL (1991) 6: 267 – 275.
-
(1991)
Hu-man PsychopharmacoL
, vol.6
, pp. 267-275
-
-
SALETU, B.1
DARRAGH, A.2
BREUEL, H.P.3
-
137
-
-
0027956093
-
Determination of linopirdine and its N-oxide metabolites in rat plasma by liquid chromatography
-
RAKESTRAW DC, BILSKI DA, LAM GN: Determination of linopirdine and its N-oxide metabolites in rat plasma by liquid chromatography. J. Pharm. Biomed. Anal. (1994) 12 (8): 1055 – 1061.
-
(1994)
J. Pharm. Biomed. Anal.
, vol.12
, Issue.8
, pp. 1055-1061
-
-
RAKESTRAW, D.C.1
BILSKI, D.A.2
LAM, G.N.3
-
139
-
-
85018860496
-
Pharmacokinetics, safety and toler-ance of DMP-543, a potential cognitive enhancer, in © Ashley Publications Ltd. All rights reserved
-
young and elderly male subjects after single oral doses. J. OM. Pharmacol. (1997) 37 (9): 867.
-
PIENIASZEK HJ, Jr., GARNER DM, KLINGERMAN CA, KORNHAUSER DM: Pharmacokinetics, safety and toler-ance of DMP-543, a potential cognitive enhancer, in © Ashley Publications Ltd. All rights reserved.Exp. Opin. Invest. Drugs (1998) 7(4) young and elderly male subjects after single oral doses. J. OM. Pharmacol. (1997) 37 (9): 867.
-
(1998)
Exp. Opin. Invest. Drugs
, vol.7
, Issue.4
-
-
PIENIASZEK, H.J.1
GARNER, D.M.2
KLINGERMAN, C.A.3
KORNHAUSER, D.M.4
-
140
-
-
0026602899
-
A group of potassium-channel blockers - acetylcholine releasers: new poten-tials for Alzheimer's disease?
-
E.P., LAVRETSKY, L.F., JARVIK, A group of potassium-channel blockers - acetylcholine releasers: new poten-tials for Alzheimer's disease?, JOM. Psychopharm., (1992), 12, 2, 110-118
-
(1992)
JOM. Psychopharm.
, vol.12
, Issue.2
, pp. 110-118
-
-
LAVRETSKY, E.P.1
JARVIK, L.F.2
|