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Volumn 9, Issue 4, 1999, Pages 391-396

Antisense oligonucleotides in the treatment of cancer

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[No Author keywords available]

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EID: 0000532453     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (11)

References (18)
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    • A review
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    • In vitro and in vivo activity of antisense inhibitors of ras: Potential for clinical development
    • COWSERT, L.M. (1997). In vitro and in vivo activity of antisense inhibitors of ras: Potential for clinical development. Anti-Cancer Drug Design 12, 359-371.
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  • 5
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    • Antisense oligonucleotides as inhibitors of signal transduction: Development from research tools to therapeutic agents
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    • Dean, N.M.1    McKay, R.2    Miraglia, L.3    Geigert, T.4    Mullert, M.5    Fabbro, D.6    Bennett, C.F.7
  • 6
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    • Toxicological and pharmacokinetic properties of chemically modified antisense oligonucleotide inhibitors of PKC-alpha and Cra/kinase
    • HENRY, S.P., MONTEITH, D., BENNETT, F.,and LEVIN, A.A. (1997). Toxicological and pharmacokinetic properties of chemically modified antisense oligonucleotide inhibitors of PKC-alpha and Cra/kinase. Anti-Cancer Drug Design 12, 409-420.
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    • Henry, S.P.1    Monteith, D.2    Bennett, F.3    Levin, A.A.4
  • 7
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    • Phase I trial of C-raf antisense oligonucleotide ISIS 5132 (CGP 69846A) by 21-day continuous intravenous infusion (CIV) in patients with advanced cancer
    • HOLMLUND, J., NEMUNAITIS, J., SCHILLER, J., DORR, A.,and K1SNER, D. (1998). Phase I trial of C-raf antisense oligonucleotide ISIS 5132 (CGP 69846A) by 21-day continuous intravenous infusion (CIV) in patients with advanced cancer. Proc. Am. Soc. Clin. Oncol. 17, 210a (abstract 811).
    • (1998) Proc. Am. Soc. Clin. Oncol. , vol.17 , pp. 210
    • Holmlund, J.1    Nemunaitis, J.2    Schiller, J.3    Dorr, A.4    Ksner, D.5
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    • Sequence-specific activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo
    • MONIA, B.P., SASMOR, H., JOHNSTON, J.F., MULLER, M.,and FABBRO, D. (1996b). Sequence-specific activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo. Proc. Natl. Acad. Sci. USA 93, 15481-15484.
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    • Role of Raf-1 serine/threonine protein kinase in growth factor signal transduction
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    • Antisense oligonucleotide therapy targeted to protein kinase C-a (ISIS 3521/CGP 64128A) by 21-day infusion: Results of the phase I trial and activity in ovarian carcinomas
    • SIKIC, B.I., YUEN, A.R., ADV AMI, R., HALSEY, J., FISHER, G.A., HOLMLUND, J.,and DORR, A. (1998). Antisense oligonucleotide therapy targeted to protein kinase C-a (ISIS 3521/CGP 64128A) by 21-day infusion: Results of the phase I trial and activity in ovarian carcinomas. Proc. ASCO 17, 429a, abstract 1654.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.