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Volumn 1, Issue 6, 1999, Pages 467-473

Synthesis and use of a 2-(trimethylsiiyl)ethoxymethyl-based linker in solid-phase organic chemistry

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EID: 0000369701     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc9900246     Document Type: Article
Times cited : (11)

References (29)
  • 1
    • 0003178552 scopus 로고    scopus 로고
    • For a review on linkers: (a) Morphy, J. R. Curr. Opin. Drug Discovery Dev. 1998, 1, 59. (b) Eggenweiler, H.-M. Drug Discovery Today 1998, 3, 552.
    • (1998) Curr. Opin. Drug Discovery Dev. , vol.1 , pp. 59
    • Morphy, J.R.1
  • 2
    • 0031792553 scopus 로고    scopus 로고
    • For a review on linkers: (a) Morphy, J. R. Curr. Opin. Drug Discovery Dev. 1998, 1, 59. (b) Eggenweiler, H.-M. Drug Discovery Today 1998, 3, 552.
    • (1998) Drug Discovery Today , vol.3 , pp. 552
    • Eggenweiler, H.-M.1
  • 17
    • 0032474703 scopus 로고    scopus 로고
    • (c) Reggelin, M.; Brenig, V.; Welcker, R. Tetrahedron Lett. 1998, 39, 4801. (molecular weight of 8) = 46.5 mg. After the reaction, 275.5 mg of resin was recovered. Therefore, 275.5 - 238.4 (theoretical starting weight) = 37.1 mg of 8 was coupled. The yield of the reaction is (37.1/46.5) × 100% = 80%. The loading of the resulting resin is (37.1/310)/0.2755 = 0.43 mmol/g.
    • (1998) Tetrahedron Lett. , vol.39 , pp. 4801
    • Reggelin, M.1    Brenig, V.2    Welcker, R.3
  • 29
    • 8744293824 scopus 로고    scopus 로고
    • note
    • This chemistry has been used for the synthesis of several libraries, which for patenting reasons will be reported in due course.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.