The design and synthesis of a scaffold for combinatorial chemistry based on bile acid

Angewandte Chemie (International Edition in English)

Volumn 35, Issue 19, 1996, Pages 2222-2224

  Wess, Günther ^a   Bock, Klaus ^a   Kleine, Horst ^a   Kurz, Michael ^a   Guba, Wolfgang ^a   Hemmerle, Horst ^a   Lopez Calle, Eloisa ^a   Baringhaus, Karl Heinz ^a   Glombik, Heiner ^a   Enhsen, Alfons ^a   Kramer, Werner ^a  

^a SANOFI   (France)

Author keywords

Bile acids; Combinatorial chemistry; Peptide mimetics; Solid phase syntheses

Indexed keywords

EID: 0030445091     PISSN: 05700833     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.199622221     Document Type: Article

References (25)

1. a) M. A. Gallop, R. W. Barrett, W. J. Dower, S. P. A. Fodor, E. M. Gordon, J. Med. Chem. 1994, 37, 1233;
2. b) E. M. Gordon, R. W. Barrett, W. J. Dower, S. P. A. Fodor, M. A. Gallop, ibid. 1994, 37, 1385;
3. c) J. A. Ellman, Chemtracts 1995, 8, 1; M. C. Pirrung, ibid. 1995, 8, 5; A. W. Czarnik, ibid. 1995, 8, 13;
4. c) J. A. Ellman, Chemtracts 1995, 8, 1; M. C. Pirrung, ibid. 1995, 8, 5; A. W. Czarnik, ibid. 1995, 8, 13;
5. c) J. A. Ellman, Chemtracts 1995, 8, 1; M. C. Pirrung, ibid. 1995, 8, 5; A. W. Czarnik, ibid. 1995, 8, 13;
6. d) L. A. Mitscher, ibid. 1995, 8, 19;
7. e) M. C. Desai. R. N. Zuckermann, W. H. Moos, Drug Dev. Res. 1994, 33, 174.
8. a) C. Gennari, H. P. Nestler, B. Solom, W. C. Still, Angew. Chem. 1995, 107, 1892; Angew. Chem. Int. Ed. Engl. 1995, 34, 1763;
9. a) C. Gennari, H. P. Nestler, B. Solom, W. C. Still, Angew. Chem. 1995, 107, 1892; Angew. Chem. Int. Ed. Engl. 1995, 34, 1763;
10. b) G. T. Wang, S. Li, N. Wideburg, G. A. Krafft, D. J. Kempf, J. Med. Chem. 1995, 38, 2995.
11. E. J. Martin, J. M. Blaney, M. A. Siani, D. C. Spellmeyer, A. K. Wong, W. H. Moos, J. Med. Chem. 1995, 38, 1431.
12. a) A. Giannis, T. Kolter, Angew. Chem. 1993, 105, 1303; Angew. Chem. Int. Ed. Engl. 1993, 32, 1244;
13. a) A. Giannis, T. Kolter, Angew. Chem. 1993, 105, 1303; Angew. Chem. Int. Ed. Engl. 1993, 32, 1244;
14. b) D. P. Fairlie, G. Abbenante, D. R. March, Curr. Med. Chem. 1995, 2, 654;
15. c) R. M. J. Liskamp, Angew. Chem. 1994, 106, 661; Angew. Chem. Int. Ed. Engl. 1994, 33, 633.
16. c) R. M. J. Liskamp, Angew. Chem. 1994, 106, 661; Angew. Chem. Int. Ed. Engl. 1994, 33, 633.
17. a) M. Lebl, V. Krchnak, N. F. Sepetor, B. Seligman, P. Strob, S. Felder, K. S. Lam, Peptide Sci. 1995, 37, 177;
18. b) R. Boyce, G. Li, H. P. Nestler, T. Suenaga, W. C. Still, J. Am. Chem. Soc. 1994, 116, 7955.
19. a) R. Hirschmann, P. A. Sprengeler, I. Kawasaki, J. W. Leahy, W. C. Shakespeare, A. B. Schmith, Tetrahedron 1993, 49, 3665;
20. b) H. Diaz, J. W. Kelly, Tetrahedron Lett. 1991, 32, 5725;
21. c) J. B. Ball, R. A. Hughes, P. F. Alewood, P. R. Andrews, Tetrahedron 1993, 49, 3567.
22. a) E. K. Kick, J. A. Ellman, J. Med. Chem. 1995, 38, 1427;
23. b) L. A. Thompson,J. A. Ellman, Tetrahedron Lett. 1994, 35, 9333.
24. a) G. Wess, W. Kramer, S. Bartmann. A. Enhsen. H. Glombik, S. Müllner, K. Bock, A. Dries, H. Kleine, W. Schmitt, Tetrahedron Lett. 1992, 33, 195;
25. b) A. P. Davis, P. J. Dorgan, E. R. Mageean, J. Chem. Soc. Chem. Commun. 1993, 492.