Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted β propeller domain

European Journal of Biochemistry

Volumn 266, Issue 3, 1999, Pages 798-810

  Abbott, Catherine A ^c   McCaughan, Geoffrey W ^c   Levy, Miriam T ^c   Church, W Bret ^a   Gorrell, Mark D ^b  

^a ST VINCENT S HOSPITAL   (Australia)

^b CENTENARY INSTITUTE   (Australia)

^c NONE

Author keywords

propeller epitopes; Adenosine deaminase; CD26; Dipeptidyl peptidase IV; Ligand binding

Indexed keywords

ADENOSINE DEAMINASE; ARGININE; DIPEPTIDYL PEPTIDASE IV; EPITOPE; LEUCINE; MONOCLONAL ANTIBODY; THREONINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; ENZYME BINDING; GENE DELETION; LIGAND BINDING; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE DEAMINASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD26; BINDING SITES; CHO CELLS; CRICETINAE; EPITOPES; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SEQUENCE DELETION; T-LYMPHOCYTES; TRANSFECTION;

EID: 0000038304     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00902.x     Document Type: Article

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