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Volumn 69, Issue 13-14, 2004, Pages 817-824

Simultaneous determination of dehydroepiandrosterone and its 7-oxygenated metabolites in human serum by high-resolution gas chromatography-mass spectrometry

Author keywords

7 Hydroxydehydroepiandrosterone; 7 Hydroxydehydroepiandrosterone; 7 Oxo dehydroepiandrosterone; Dehydroepiandrosterone; Gas chromatography mass spectrometry; Serum

Indexed keywords

7 OXODEHYDROEPIANDROSTERONE; 7ALPHA HYDROXYPRASTERONE; 7BETA HYDROXYPRASTERONE; ANDROSTERONE DERIVATIVE; ETHER DERIVATIVE; METHOXYAMINE; ORGANIC SOLVENT; PRASTERONE; SULFATASE; UNCLASSIFIED DRUG;

EID: 9944233534     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2004.08.003     Document Type: Article
Times cited : (18)

References (31)
  • 2
    • 0029027469 scopus 로고
    • Occurrence of cytochrome P450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract
    • L. Dalla Valle, J. Couet, Y. Labrie, J. Simard, P. Belvedere, and C. Simontacchi Occurrence of cytochrome P450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract Mol Cell Endocrinol 111 1995 83 92
    • (1995) Mol Cell Endocrinol , vol.111 , pp. 83-92
    • Dalla Valle, L.1    Couet, J.2    Labrie, Y.3    Simard, J.4    Belvedere, P.5    Simontacchi, C.6
  • 3
    • 0029549968 scopus 로고
    • Human dehydroepiandrosterone sulfotransferase. Purification, molecular cloning, and characterization
    • C.N. Falany, K.A. Comer, T.P. Dooley, and H. Glatt Human dehydroepiandrosterone sulfotransferase. Purification, molecular cloning, and characterization Ann NY Acad Sci 774 1995 59 72
    • (1995) Ann NY Acad Sci , vol.774 , pp. 59-72
    • Falany, C.N.1    Comer, K.A.2    Dooley, T.P.3    Glatt, H.4
  • 4
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
    • N. Orentreich, J.L. Brind, R.L. Rizer, and J.H. Vogelman Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood J Clin Endocrinol Metab 59 1984 551 555
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.H.4
  • 5
    • 0031816232 scopus 로고    scopus 로고
    • The actions of exogenous dehydroepiandrosterone in experimental animals and humans
    • F. Svec, and J.R. Porter The actions of exogenous dehydroepiandrosterone in experimental animals and humans Proc Soc Exp Biol Med 218 1998 174 191
    • (1998) Proc Soc Exp Biol Med , vol.218 , pp. 174-191
    • Svec, F.1    Porter, J.R.2
  • 6
    • 0013974892 scopus 로고
    • Digitonin precipitable steroids in normal human urine
    • A.M. Bongiovanni Digitonin precipitable steroids in normal human urine J Clin Endocrinol Metab 26 1966 1240 1244
    • (1966) J Clin Endocrinol Metab , vol.26 , pp. 1240-1244
    • Bongiovanni, A.M.1
  • 7
    • 0018257665 scopus 로고
    • Products of dehydroepiandrosterone metabolism by human mammary tumors and their influence on estradiol receptor binding
    • K. Li, T. Foo, and J.B. Adams Products of dehydroepiandrosterone metabolism by human mammary tumors and their influence on estradiol receptor binding Steroids 31 1978 113 127
    • (1978) Steroids , vol.31 , pp. 113-127
    • Li, K.1    Foo, T.2    Adams, J.B.3
  • 8
    • 0027055261 scopus 로고
    • Neurosteroid metabolism. 7α-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes
    • Y. Akwa, R.F. Morfin, P. Robel, and E.E. Baulieu Neurosteroid metabolism. 7α-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes Biochem J 288 1992 959 964
    • (1992) Biochem J , vol.288 , pp. 959-964
    • Akwa, Y.1    Morfin, R.F.2    Robel, P.3    Baulieu, E.E.4
  • 9
    • 0030273492 scopus 로고    scopus 로고
    • Studies of the enzyme complex responsible for pregnenolone and dehydroepiandrosterone 7α-hydroxylation in mouse tissues
    • J. Doostzadeh, and R. Morfin Studies of the enzyme complex responsible for pregnenolone and dehydroepiandrosterone 7α-hydroxylation in mouse tissues Steroids 61 1996 613 620
    • (1996) Steroids , vol.61 , pp. 613-620
    • Doostzadeh, J.1    Morfin, R.2
  • 10
    • 0031283159 scopus 로고    scopus 로고
    • Dehydroepiandrosterone 7α- and 7β-hydroxylation in mouse brain microsomes. Effects of cytochrome P450 inhibitors and structure-specific inhibition by steroid hormones
    • J. Doostzadeh, A.C. Cotillon, and R. Morfin Dehydroepiandrosterone 7α- and 7β-hydroxylation in mouse brain microsomes. Effects of cytochrome P450 inhibitors and structure-specific inhibition by steroid hormones J Neuroendocrinol 9 1997 923 928
    • (1997) J Neuroendocrinol , vol.9 , pp. 923-928
    • Doostzadeh, J.1    Cotillon, A.C.2    Morfin, R.3
  • 11
    • 0031788908 scopus 로고    scopus 로고
    • Inhibition studies of dehydroepiandrosterone 7α- and 7β-hydroxylation in mouse liver microsomes
    • J. Doostzadeh, A.C. Cotillon, A. Benalycherif, and R. Morfin Inhibition studies of dehydroepiandrosterone 7α- and 7β-hydroxylation in mouse liver microsomes Steroids 63 1998 608 614
    • (1998) Steroids , vol.63 , pp. 608-614
    • Doostzadeh, J.1    Cotillon, A.C.2    Benalycherif, A.3    Morfin, R.4
  • 12
    • 0033233117 scopus 로고    scopus 로고
    • 7β-OH-DHEA counteracts dexamethasone induced suppression of primary immune response in murine spleenocytes
    • I. Sterzl, R. Hampl, J. Sterzl, J. Votruba, and L. Starka 7β-OH-DHEA counteracts dexamethasone induced suppression of primary immune response in murine spleenocytes J Steroid Biochem Mol Biol 71 1999 133 137
    • (1999) J Steroid Biochem Mol Biol , vol.71 , pp. 133-137
    • Sterzl, I.1    Hampl, R.2    Sterzl, J.3    Votruba, J.4    Starka, L.5
  • 13
    • 0034124497 scopus 로고    scopus 로고
    • Dexamethasone-induced apoptosis of mouse thymocytes: Prevention by native 7α-hydroxysteroids
    • V. Chmielewski, F. Drupt, and R. Morfin Dexamethasone-induced apoptosis of mouse thymocytes: prevention by native 7α-hydroxysteroids Immunol Cell Biol 78 2000 238 246
    • (2000) Immunol Cell Biol , vol.78 , pp. 238-246
    • Chmielewski, V.1    Drupt, F.2    Morfin, R.3
  • 14
    • 0029056829 scopus 로고
    • Ergosteroids: Induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone
    • H. Lardy, B. Partridge, N. Kneer, and Y. Wei Ergosteroids: induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone Proc Natl Acad Sci USA 92 1995 6617 6619
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6617-6619
    • Lardy, H.1    Partridge, B.2    Kneer, N.3    Wei, Y.4
  • 15
    • 0033968952 scopus 로고    scopus 로고
    • The effect of 7-oxo-DHEA acetate on memory in young and old C57BL/6 mice
    • J. Shi, S. Schulze, and H.A. Lardy The effect of 7-oxo-DHEA acetate on memory in young and old C57BL/6 mice Steroids 65 2000 124 129
    • (2000) Steroids , vol.65 , pp. 124-129
    • Shi, J.1    Schulze, S.2    Lardy, H.A.3
  • 16
    • 0017752453 scopus 로고
    • A radioimmunoassay for 7α-hydroxy dehydroepiandrosterone in human plasma
    • S.J.M. Skinner, C.J.P. Tobler, and RA.F. Couch A radioimmunoassay for 7α-hydroxy dehydroepiandrosterone in human plasma Steroids 30 1977 315 330
    • (1977) Steroids , vol.30 , pp. 315-330
    • Skinner, S.J.M.1    Tobler, C.J.P.2    Couch, R.F.3
  • 17
    • 0342615015 scopus 로고    scopus 로고
    • Immunoassay of 7-hydroxysteroids: 2. Radioimmunoassay of 7α-hydroxy dehydroepiandrosterone
    • O. Lapcík, R. Hampl, M. Hill, and L. Stárka Immunoassay of 7-hydroxysteroids: 2. Radioimmunoassay of 7α-hydroxy dehydroepiandrosterone J Steroid Biochem Mol Biol 71 1999 231 237
    • (1999) J Steroid Biochem Mol Biol , vol.71 , pp. 231-237
    • Lapcík, O.1    Hampl, R.2    Hill, M.3    Stárka, L.4
  • 18
    • 0032457353 scopus 로고    scopus 로고
    • Immunoassay of 7-hydroxysteroids: 1. Radioimmunoassay of 7β-hydroxy dehydroepiandrosterone
    • O. Lapcík, R. Hampl, M. Hill, M. Bicíková, and L. Stárka Immunoassay of 7-hydroxysteroids: 1. Radioimmunoassay of 7β-hydroxy dehydroepiandrosterone J Steroid Biochem Mol Biol 67 1998 439 445
    • (1998) J Steroid Biochem Mol Biol , vol.67 , pp. 439-445
    • Lapcík, O.1    Hampl, R.2    Hill, M.3    Bicíková, M.4    Stárka, L.5
  • 19
    • 0032997455 scopus 로고    scopus 로고
    • Development and validation of a high-performance liquid chromatography assay for the quantitative determination of 7-oxo-dehydroepiandrosterone- 3β-sulfate in human plasma
    • A. Marwah, P. Marwah, and H. Lardy Development and validation of a high-performance liquid chromatography assay for the quantitative determination of 7-oxo-dehydroepiandrosterone-3β-sulfate in human plasma J Chromatogr 721 1999 197 205
    • (1999) J Chromatogr , vol.721 , pp. 197-205
    • Marwah, A.1    Marwah, P.2    Lardy, H.3
  • 20
    • 0020027945 scopus 로고
    • Analysis of neutral steroid sulfates by glass capillary gas chromatography-mass spectrometry (GC-MS) from blood of a patient with paraquat poisoning
    • H. Ludwig-Köhn, A. Sziedat, D. Matthaei, and H.V. Henning Analysis of neutral steroid sulfates by glass capillary gas chromatography-mass spectrometry (GC-MS) from blood of a patient with paraquat poisoning Clin Chim Acta 121 1982 189 198
    • (1982) Clin Chim Acta , vol.121 , pp. 189-198
    • Ludwig-Köhn, H.1    Sziedat, A.2    Matthaei, D.3    Henning, H.V.4
  • 21
    • 0031610297 scopus 로고    scopus 로고
    • Change of 7α-hydroxy-dehydroepiandrosterone levels in serum of mice treated by cytochrome P450-modifying agents
    • S. Attal-Khémis, V. Dalmeyda, and R. Morfin Change of 7α-hydroxy-dehydroepiandrosterone levels in serum of mice treated by cytochrome P450-modifying agents Life Sci 63 1998 1543 1553
    • (1998) Life Sci , vol.63 , pp. 1543-1553
    • Attal-Khémis, S.1    Dalmeyda, V.2    Morfin, R.3
  • 22
    • 0034739781 scopus 로고    scopus 로고
    • Immunomodulatory 7-hydroxylated metabolites of dehydroepiandrosterone are present in human semen
    • R. Hampl, M. Hill, I. Sterzl, and L. Stárka Immunomodulatory 7-hydroxylated metabolites of dehydroepiandrosterone are present in human semen J Steroid Biochem Mol Biol 75 2000 273 276
    • (2000) J Steroid Biochem Mol Biol , vol.75 , pp. 273-276
    • Hampl, R.1    Hill, M.2    Sterzl, I.3    Stárka, L.4
  • 23
    • 0035940722 scopus 로고    scopus 로고
    • 7-Hydroxydehydroepiandrosterone epimers in human serum and saliva. Comparison of gas chromatography-mass spectrometry and radioimmunoassay
    • M. Hill, O. Lapcík, H. Havlíková, R. Morfin, and R. Hampl 7-Hydroxydehydroepiandrosterone epimers in human serum and saliva. Comparison of gas chromatography-mass spectrometry and radioimmunoassay J Chromatogr 935 2001 297 307
    • (2001) J Chromatogr , vol.935 , pp. 297-307
    • Hill, M.1    Lapcík, O.2    Havlíková, H.3    Morfin, R.4    Hampl, R.5
  • 24
    • 0037211772 scopus 로고    scopus 로고
    • Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines
    • S. Yoshida, A. Honda, Y. Matsuzaki, S. Fukushima, N. Tanaka, and A. Takagiwa Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines Steroids 68 2003 73 83
    • (2003) Steroids , vol.68 , pp. 73-83
    • Yoshida, S.1    Honda, A.2    Matsuzaki, Y.3    Fukushima, S.4    Tanaka, N.5    Takagiwa, A.6
  • 25
    • 12644312578 scopus 로고
    • Oxidation of long-chain and related alcohols to carbonyls by dimethyl sulfoxide "activated" by oxalyl chloride
    • A.J. Mancuso, S. Huang, and D. Swern Oxidation of long-chain and related alcohols to carbonyls by dimethyl sulfoxide "activated" by oxalyl chloride J Org Chem 43 1978 2480 2482
    • (1978) J Org Chem , vol.43 , pp. 2480-2482
    • Mancuso, A.J.1    Huang, S.2    Swern, D.3
  • 26
    • 0034836384 scopus 로고    scopus 로고
    • Hydrolysis of conjugated steroids by the combined use of β-glucuronidase preparations from helix pomatia and ampullaria: Determination of urinary cortisol and its metabolites
    • H. Shibasaki, C. Tanabe, T. Furuta, and Y. Kasuya Hydrolysis of conjugated steroids by the combined use of β-glucuronidase preparations from helix pomatia and ampullaria: determination of urinary cortisol and its metabolites Steroids 66 2001 795 801
    • (2001) Steroids , vol.66 , pp. 795-801
    • Shibasaki, H.1    Tanabe, C.2    Furuta, T.3    Kasuya, Y.4
  • 27
    • 0028816863 scopus 로고
    • Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry
    • S. Dzeletovic, O. Breuer, E. Lund, and U. Diczfalusy Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry Anal Biochem 225 1995 73 80
    • (1995) Anal Biochem , vol.225 , pp. 73-80
    • Dzeletovic, S.1    Breuer, O.2    Lund, E.3    Diczfalusy, U.4
  • 28
    • 0028178097 scopus 로고
    • Determination of 7α-hydroxy-4-cholesten-3-one level in plasma using isotope-dilution mass spectrometry and monitoring its circadian rhythm in human as an index of bile acid biosynthesis
    • T. Yoshida, A. Honda, N. Tanaka, Y. Matsuzaki, J. Shoda, and B-F. He Determination of 7α-hydroxy-4-cholesten-3-one level in plasma using isotope-dilution mass spectrometry and monitoring its circadian rhythm in human as an index of bile acid biosynthesis J Chromatogr 655 1994 179 187
    • (1994) J Chromatogr , vol.655 , pp. 179-187
    • Yoshida, T.1    Honda, A.2    Tanaka, N.3    Matsuzaki, Y.4    Shoda, J.5    He, B.-F.6
  • 29
    • 0017457835 scopus 로고
    • Use of new silylating agents for identification of hydroxylated steroids by gas chromatography and gas chromatography mass spectrometry
    • H. Miyazaki, M. Ishibashi, M. Itoh, and T. Nambara Use of new silylating agents for identification of hydroxylated steroids by gas chromatography and gas chromatography mass spectrometry Biomed Mass Spectrom 4 1977 23 35
    • (1977) Biomed Mass Spectrom , vol.4 , pp. 23-35
    • Miyazaki, H.1    Ishibashi, M.2    Itoh, M.3    Nambara, T.4
  • 30
    • 0023663642 scopus 로고
    • Gas chromatography-mass spectrometry of some prostanoids with new derivatizing agents
    • K. Yamashita, K. Watanabe, M. Ishibashi, H. Miyazaki, K. Yokota, and K. Horie Gas chromatography-mass spectrometry of some prostanoids with new derivatizing agents J Chromatogr 399 1987 223 234
    • (1987) J Chromatogr , vol.399 , pp. 223-234
    • Yamashita, K.1    Watanabe, K.2    Ishibashi, M.3    Miyazaki, H.4    Yokota, K.5    Horie, K.6
  • 31
    • 0035166407 scopus 로고    scopus 로고
    • 7-Hydroxydehydroepiandrosterone epimers in the life span
    • R. Hampl, M. Hill, and L. Stárka 7-Hydroxydehydroepiandrosterone epimers in the life span J Steroid Biochem Mol Biol 78 2001 367 372
    • (2001) J Steroid Biochem Mol Biol , vol.78 , pp. 367-372
    • Hampl, R.1    Hill, M.2    Stárka, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.