1H high-resolution magic-angle spinning (HR-MAS) NMR analysis of ligand density on resins using a resin internal standard

Analytical and Bioanalytical Chemistry

Volumn 380, Issue 4, 2004, Pages 627-631

  Lucas, Laura H ^a   Cerny, Matthew A ^a   Koen, Yakov M ^a   Hanzlik, Robert P ^a   Larive, Cynthia K ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

1H NMR spectroscopy; HR MAS; Quantitation; Resin loading analysis

Indexed keywords

ADSORBENTS; AFFINITY CHROMATOGRAPHY; ENZYMES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PURIFICATION; SOLVENTS;

CYTOCHROME; ENZYME PURIFICATION; HIGH-RESOLUTION MAGIC-ANGLE SPINNING (HR-MAS); LIGANDS;

RESINS;

11 (1' IMIDAZOLYL) 3,6,9 TRIOXAUNDECANOIC ACID; CYTOCHROME P450 4A; DECANOIC ACID DERIVATIVE; LIGAND; RESIN; UNCLASSIFIED DRUG; TRITIUM;

AFFINITY CHROMATOGRAPHY; ARTICLE; COMPOSITE MATERIAL; ENZYME PURIFICATION; HIGH RESOLUTION MAGIC ANGLE SPINNING SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; QUANTUM YIELD; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; INSTRUMENTATION; METHODOLOGY; METHYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; STANDARD;

ANIMALS; CHROMATOGRAPHY, AFFINITY; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; METHYLATION; MOLECULAR STRUCTURE; RATS; REFERENCE STANDARDS; RESINS, SYNTHETIC; TRITIUM;

EID: 9944221080     PISSN: 16182642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00216-004-2781-0     Document Type: Article

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