Expression of HLA class 1-specific inhibitory receptors by chronically activated cytolytic T lymphocytes: Useful or harmful to the host?

Melanoma Research

Volumn 7, Issue SUPPL. 2, 1997, Pages

  Mingari, Maria Cristina ^a,b   Ponte, Marco ^b   Vitale, Chiara ^b   Schiavetti, Francesca ^b   Bertone, Stefania ^b   Moretta, Lorenzo ^a,b  

^a UNIVERSITY OF GENOA   (Italy)

^b CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

Cytolytic T lymphocytes; HLA class 1 molecules; Inhibitory receptors; Natural killer cells; T cell expansion

Indexed keywords

HLA ANTIGEN CLASS 1;

ANTIGEN EXPRESSION; ARTICLE; CANCER IMMUNOLOGY; HLA SYSTEM; HUMAN; LYMPHOCYTE ACTIVATION; MELANOMA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 9844229373     PISSN: 09608931     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Ljunggren H-G, Karre K. In search of the 'missing self. MHC molecules and NK cell recognition. Immunol Today 1990; 11:237-241.
2. Karre K. An unexpected petition for pardon. Curr 1992; 2:613-616.
3. Moretta L, Ciccone F, Moretta A, Höglund P, Öhlen C, Kärre K. Allorecognition by NK cells: nonself or no self? Immunol Today 1992; 13:300-306.
4. Storkus WJ, Howell DN, Salter RD, Dawson JR, Cresswell P. NK susceptibility varies inversely with target cell class I HLA antigen expression. J Immunol 1987; 138:1657-1659.
5. Shimizu Y, DeMars R. Demonstration by class I gene transfer that reduced susceptibility of human cells to natural killer cell-mediated lysis is inversely correlated with HLA class I antigen expression. Eur J Immunol 1989; 19:447-451.
6. Correa I, Corral L, Raulet DH. Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells. Eur J Immunol 1994; 24:1323-1331.
7. Liao NS, Bix M, Zijstra M, Jaenisch R, Raulet D. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 1991; 253:199-202.
8. Ljunggren HG, Kaer LV, Ploegh HL, Tonegawa S. Altered natural killer cell repertoire in Tap-1 mutant mice. Proc Natl Acad Sci USA 1994; 91:6521-6524.
9. Stam NJ, Kast WM, Voordouw AC, et al. Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells. J Immunol 1989; 142:4113-4117.
10. Moretta A, Tambussi G, Bottino C, et al. A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolylic function. J Exp Med 1990; 171:695-714.
11. Moretta A, Bottino C, Pende D, et al. Identification of four subsets of human CD3- CD16+ NK cells by the expression of clonally distributed functional surface molecules. Correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J Exp Med 1990; 172:1589-1598.
12. Ciccone E, Pende D, Viale O, et al. Evidence of a natural killer (NK) cell repertoire for (allo)antigen recognition: definition of five distinct NK-determined allospecificities in humans. J Exp Med 1992; 175:709-718.
13. Moretta A, Vitale M, Bottino C, et al. P58 molecules as putative receptors for MHC class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J Exp Med 1993; 178:597-604.
14. Ciccone E, Pende D, Viale O, et al. Involvement of HLA class I alleles in NK cell specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2). J Exp Med 1992; 176:963-971.
15. k kinase. Eur J Immunol 1994; 24:2527-2534.
16. Colonna M, Spies T, Strominger JL, et al. Alloantigen recognition by human natural killer cells is associated with HLA-C or a closely linked gene. Proc Natl Acad Sci USA 1992; 89:7983-7985.
17. Biassoni R, Falco M, Cambiaggi A, et al. Amino acid substitutions can influence the NK-mediated recognition of HLA-C molecules. Role ol Serinc-77 and lysine-80 in the target cell protection from lysis mediated by 'group 2' or 'group 1' NK clones. J Exp Med 1995; 182:605-609.
18. Moretta A, Vitale M, Sivori S, et al. Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J Exp Med 1994; 180:545-555.
19. Moretta A, Bottino C, Vitale M, et al. Receptors for HLA-class I-molecules in human natural killer cells. Alum Her Immunol 1996; 14:619-648
20. Litwin V, Gumperz JE, Parham P, Phillips JH, Lanier LL: NKBI: a nautral killer tell recepltir involved in the recognition of polymorphic HLA-B molecules. J Exp Med 1994; 180:537-542.
21. Gumperz JE, Litwin V, Phillips JH, Lanier LL, Parham P. The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J Exp Med 1995; 181:1133-1114.
22. Pende D, Biassoni R, Cantoni C, et al. The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors which is characterized by three Ig-like domains and is expressed as a 140 kD disulphide-linked dimer. J Exp Med 1996; 184:505-518.
23. Vitale M, Sivori S, Pende D, et al. Physical and functional independency of p70 and p58 NK cell receptors for HLA-class I. Their role in the definition of different groups of alloreactive NK cell clones. Proc Natl Acad Sci USA 1996; 93:1453-1457.
24. Wagtmann N, Biassoni R, Cantoni C, et al. Molecular clones of the p58 NK cell receptor reveal immunoglobulin related molecules with diversity in both the extra- and intracellular domains. Immunity 1995; 2:439-449.
25. D'Andrea A, Chang C, Franz-Bacon K, McClanahan T, Phillips JH, Lanier LL: Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol 1995; 155:2306-2310.
26. Aramburu J, Balboa MA, Ramirez A, et al. A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-γ/δ+ T lymphocytes. Inhibition of IL-2 dependent proliferation by anti-Kp43 monoclonal antibody. J Immunol 1990; 44:3238-3247.
27. Aramburu J, Balboa MA, Izquierdo M, Lopez-Botet M. A novel functional cell surface dimer (Kp43) expressed by natural killer cells and TCR T lymphocytes. II. Modulation of natural killer cytotoxicity by anti-Kp43 monoclonal antibody. J Immunol 1991; 147:714-721.
28. Chang C, Rodriguez A, Carretero M, Lopez-Botet M, Phillips JH, Lanier LL. Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily. Eur Immunol 1995; 25:2433-2437.
29. Sivori S, Vitale M, Bottino C, et al. CD94 functions as a natural killer cell inhibitory receptor for different HLA-class-I alleles. Identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies. Eur J Immunol 1996; 26:2487-2492.
30. Phillips JH, Chang C, Mallison J, Gumperz JE, Parham P, Lanier LL. CD94 and a novel associated protein (94AP) form of NK cell receptor involved in the recognition of HLA-A, HLA-B and HLA-C allotypes. Immunity 1996; 5:163-172
31. Olcese L, Lang P, Vély F, et al. Human and mouse natural killer cell inhibitory receptors recruit the PTP1C and PTP1D protein tyrosine phosphatases. J Immunol 1996; 156:4531-4534.
32. Burshtyn DN, Scharenberg AM, Wagtmann N, et al. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitory receptor. Immunity 1996; 4:77-85.
33. Ferrini S, Miescher S, Zocchi MR, Von Fliedner V, Moretta A. Phenotypic and functional characterization of recombinant interleukin-2 (rIL-2)-induced activated killer cells. Analysis at the population and clonal levels. J Immunol 1987; 138:1297-1302.
34. Mingari MC, Vitale C, Cambiaggi A, et al. Cytolytic T lymphocytes displaying natural killer (NK)-like activity: expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production. Int Immunol 1995; 7:697-703.
35. Mingari MC, Vitale C, Schiavetti F, et al. HLA-class I-specific inhibitory receptors of NK type on a subset of human T cells. Chem Immunol 1996; 64:135-145.
36. Phillips JH, Gumberz JE, Parham P, Lanier LL. Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptor on T lymphocytes. Science 1995; 128:403-405.
37. Mingari MC, Schiavetti F, Ponte M, et al. Human CD8+ T lymphocyte subsets that express HLA-class I specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. Proc Natl Acad Sci U S A 1996; 93:12433-12438.
38. Gray D. Immunological memory. Ann Rev Immunol 1993; 11:49.
39. Mingari MC, Ponte MC, Cantoni C, et al. HLA-class I-specific inhibitory receptors in human cytotylic T lymphocytes. Molecular characterization, distribution in lymphoid tissues and coexpression by individual T cells. Int Immunol 1997; 9:485-491.
40. De Maria A, Ferraris A, Guastella M, et al. Expression of HLA class I-specific inhibitory natural killer cell receptors in HIV-specific cytolytic T lymphocytes: impairment of specific cytolytic functions. Proc Natl Acad Sci USA (in press).
41. highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus. J Immunol 1995; 155:5046-5056.
42. Pantaleo G, Demarest JF, Soudeyns H, et al. Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV. Nature 1994; 370:463-467.
43. Utz U., Banks D, Jacobson S, Biddison WE. Analysis of the T-cell receptor repertoire of human T-cell leukemia virus type-1 (HTLV-1). Tax-specific CD8+ cytotoxic T lymphocytes from patients with HTLV-1-associated disease: evidence for oligoclonal expansion. J Virology 1996; 70:843-851.
44. Fitzgerald JE, Ricalton NS, Meyer AC, et al. Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arhtiritis. J Immunol 1995; 154:3538-3547.
45. Cauda R, Coletti D, Lucia MB, et al. Analysis of natural killer (NK) cell susets defined by the expression of two novel surface antigens (EB6 and GL183) in AIDS and AIDS-related conditions. Clin Immunol Immunopathol 1994; 70:198-205.
46. Brunner KT, MacDonald HR, Cerottini J-C. Quantification and clonal isolation of cytolytic T lymphocyte precursors selectively infiltrating murine sarcoma virus-induced tumors. J Exp Med 1981; 154:362- 373.
47. Anichini A, Fossati G, Parmiani G. Clonal analysis of the cytolytic T cell response to human tumors. Immunol Today 1987; 8:385-390.
48. Traversari C, van der Bruggen P, Luescher IF, et al. A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E. J Exp Med 1992; 176:1453-1457.
49. Wolfel T, van Pel A, Brichard V, et al. Two tyrosinase nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes. Eur J Immunol 1994; 24:759-764.
50. Cox AL, Skipper J, Chen Y, et al. Identification of a peptide recognised by five melanoma-specific human cytoloxic T cell lines. Science 1994; 264:716-719.
51. Ikeda H, Lethé B, Lehmann F, et al. Cytolytic T cells expressing NK inhibitory p58.2 recognize on a melanoma metastasis lacking HLA-Cw7 an antigen by a gene which is preferentially expressed in tumors. Immunity 1997, 6:199-208.