HLA-Class I-specific inhibitory receptors of NK type on a subset of human T cells

Chemical Immunology

Volumn 64, Issue , 1996, Pages 135-145

  Mingari, Maria Cristina ^a,b   Vitale, Chiara ^a   Schiavetti, Francesca ^a   Cambiaggi, Anna ^a   Bertone, Stefania ^a   Zunino, Andrea ^a   Ponte, Marco ^a  

^a CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; HLA ANTIGEN CLASS 1; LYMPHOCYTE RECEPTOR;

HLA SYSTEM; HUMAN; LARGE GRANULAR LYMPHOCYTE; LYMPHOPROLIFERATIVE DISEASE; NATURAL KILLER CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE SUBPOPULATION;

HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; IMMUNOLOGIC MEMORY; KILLER CELLS, NATURAL; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTE SUBSETS;

EID: 0029800506     PISSN: 10150145     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (51)

1. Ljunggren H-G, Kärre K: In search of the 'missing self. MHC molecules and NK ceil recognition, Immunol Today 1990;11:237-244.
2. Kärre K. An unexpected petition for pardon. Curr Biol 1992,2:613-616.
3. Moretta L, Ciccone E, Moretta A, Höglund P, Öhlen C, Kärre K. Allorecognition by NK cells: Nonself or no self? Immunol Today 1992; 13:300-306
4. Ciccone E, Pende D, Viale O, Di Donato C, Tripodi G, Orengo AM, Guardiola J, Moretta A, Moretta L: Evidence of a natural killer (NK) cell repertoire for (allo)antigen recognition: Definition of five distinct NK-determined allospecificities in humans. J Exp Med 1992;175:709-718.
5. Storkus WJ, Howell DN, Salter RD, Dawson JR, Cresswell P: NK susceptibility varies inversely with target cell class I HLA antigen expression. J Immunol 1987;138:1657-1659.
6. Moretta L, Ciccone E, Mingan MC, Biassoni R, Moretta A: Human NK cells: Origin, clonality, specificity and receptors Adv Immunol 1994;55:341-380.
7. Shimizu Y, DeMars R: Demonstration by class I gene transfer that reduced susceptibility of human cells to natural killer cell-mediated lysis is inversely correlated with HLA class I antigen expression. Eur J Immunol 1989;19:447-451.
8. Burgert HG, Maryanski HL, Kvist S: E3/19K protein of adenovirus type 2 inhibits lysis of cytolytic T lymphocytes by blocking cell-surface expression of histocompatibility class 1 antigens. Proc Natl Acad Sci USA 1987;84:1356-1360.
9. Correa I, Corral L, Raulet DH. Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells. Eur J Immunol 1994:24:1323-1331.
10. Liao NS, Bix M, Zijstra M, Jaenisch R, Raulet D: MHC class I deficiency: Susceptibility to natural killer (NK) cells and impaired NK activity. Science 1991;253:199-202.
11. Ljunggren HG, Kaer LV, Ploegh HL, Tonegawa S: Altered natural killer cell repertoire in Tap-1 mutant mice. Proc Natl Acad Sci USA 1994;91:6521-6524.
12. Stam NJ, Kast WM, Voordouw AC, Pastoors LB, Van Der Hoeven FA, Mehef CJM, Ploegh HL: Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma by natural killer cells. J Immunol 1989;142:4113-4117.
13. Ciccone E, Pende D, Viale O, Di Donato C, Orengo AM, Biassoni R, Verdiani S, Amoroso A, Moretta A, Moretta L: Involvement of HLA class I alleles in NK cell-specific functions: Expression of HLA-CwS confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2). J Exp Med 1992;176:963-971
14. Moretta A, Vitale M, Bottino C, Orengo AM, Morelh L, Augugliaro R, Barbaresi M, Ciccone E, Moretta L: p58 molecules as putative receptors for MHC class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J Exp Med 1993;178:597-604.
15. lck kinase. Eur J Immunol 1994;24:2527-2534.
16. Christiansen FT, Witt CS, Ciccone E, Townend D, Pende D, Viale O, Abraham LJ, Dawkins RL, Moretta L: Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex: Ancestral haplotypes encode particular NK-defined haplotypes. J Exp Med 1993; 178 1033-1039.
17. Colonna M, Spies T, Strorminger JL, Ciccone E, Moretta A, Moretta L, Pende D, Viale O. Alloantigen recognition by human natural killer cells is associated with HLA-C or a closely linked gene. Proc Natl Acad Sci USA 1992;89:7983-7985
18. Colonna M, Borsellino G, Falco M, Ferrara GB, Strominger JL: HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells. Proc Natl Acad Sci USA 1993;90:12000-12004.
19. Biassoni R, Falco M, Cambiaggi A, Costa P, Verdiani S, Pende D, Conte R, Di Donato C, Parham P, Moretta L: Amino acid substitutions can influence the NK-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by 'group 2' or 'group 1' NK clones. J Exp Med 1995;182:605-609.
20. Moretta A, Vitale M, Sivori S, Bottino C, Morelli L, Augugharo R, Barbaresi M, Pende D, Ciccone E, Lopez-Botet M, Moretta L: Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J Exp Med 1994; 180:545-555.
21. Litwin V, Gumperz JE, Parham P, Phillips JH, Lamer L: NKB1: A natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med 1994;180:537:543.
22. Cella M, Longo A, Ferrara GB, Strominger JL, Colonna M: NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine-80. J Exp Med 1994;180:1235-1242.
23. Gumperz JE, Litwin V, Phillips JH, Lanier LL, Parham P: The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J Exp Med 1995;181:1133-1144.
24. D'Andrea A, Chang C, Franz-Bacon K, McClanahan T, Phillips JH, Lanier LL: Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol 1995;155:2306-2310.
25. Aramburu J, Balboa MA, Ramirez A, Silva A, Acevedo A, Sanchez-Madrid F, de Landàzuri MO, Lòpez-Botet M: A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptors-γ/δ+ T lymphocytes Inhibition of IL-2-dependent proliferation by anti-Kp43 monoclonal antibody. J Immunol 1990; 44:3238-3247.
26. Aramburu J, Balboa MA, Izquierdo M, Lopez-Botet M: A novel functional cell surface dimer (Kp43) expressed by natural killer cells and TCR T lymphocytes. II. Modulation of natural killer cytotoxicity by anti-Kp43 monoclonal antibody. J Immunol 1991;147:714-721
27. Pende D, Biassoni R, Cantoni C, Verdiani S, Falco M, Di Donato C, Accame L, Bottino C, Moretta A, Moretta L: The Natural Killer cell receptor specific for HLA-A allotypes: A novel member of the p58/p70 family of inhibitory receptors which is characterized by three Ig-like domains and is expressed as a 140 kD disulphide-linked dimer. J Exp Med 1996;184:1-14
28. Ciccone E, Pende D, Nanni L, di Donato C, Viale O, Beretta A, Vitale M, Sivori S, Moretta A, Moretta L: General role of HLA class I molecules in the protection of target cells from lysis by NK cells. Evidence that the free heavy chain of class I molecules are not sufficient to mediate the protective effect Int Immunol 1992;7:393-400
29. Ciccone E, Pende D, Vitale ML, Nannni L, Di Donato C, Bottino C, Morelli L, Viale O, Amoroso A, Moretta A, Moretta L: Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells. Eur J immunol 1994;24:1003-1006.
30. Vitale M, Sivori S, Pende D, Augugliaro R, Di Donato C, Amoroso A, Malnati M, Bottino C, Moretta L, Moretta A: Physical and functional independency of p70 an p58 NK cell receptors for HLA-class I. Their role in the definition of different groups of alloreactive NK cell clones. Proc Natl Acad Sci USA, in press.
31. Ferrini S, Cambiaggi A, Meazza R, Sforzini S, Marciano S, Mingari MC, Moretta L: T cell clones expressing the NK-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function. Eur J Immunol 1994;24:2294-2298
32. Mingari MC, Vitale C, Cambiaggi A, Schiavetti F, Melioli G, Ferrini S, Poggi A Cytolytic T lymphocytes displaying natural killer (NKJ)-like activity: Expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production. Int Immunol 1995;7:697-703.
33. Phillips JH, Gumberz JE, Parham P, Lanier LL: Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptor on T lymphocytes. Science 1995;128:403-405.
34. Chan PY, Taken F: Expression of a T-cell receptor-like molecule on normal and malignant murine T cells detected by rat monoclonal antibody nonclonotypic determinant. J Immunol 1986;136: 1346-1353.
35. Nagasawa R, Gross J, Kanagawa O, Townsend K, Lanier LL, Chiller J, Allison JP: Identification of a novel T-cell surface disulphide-bounded dimer distinct from the α/β antigen receptor. J Immunol 1987;138:815-824.
36. Roland J, Cazenawe PA- Ly49 antigen defines an α/β TCR population in i-IEL with an extrathymic maturation. Int Immunol 1992;4:699-706.
37. Moretta A, Tambussi G, Bottino C, Tripodi G, Merli A, Ciccone E, Pantaleo G, Moretta L: A novel surface antigen expressed by a subset of human CD3-CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med 1990;171:695-714.
38. Moretta A, Bottino C, Pende D, Tripodi G, Tambussi G, Viale O, Orengo A, Barbaresi M, Merli A, Ciccone E, Moretta L: Identification of four subsets of human CD3-CD16+ NK cells by the expression of clonally distributed functional surface molecules. Correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J Exp Med 1990; 172:1589-1598.
39. Lanier LL, Phillips H: Molecular and cell biology of inhibitory MHC class I receptors on NK cells and T cells. Immunol Today 1996;17:86-91.
40. Mingari MC, Schiavetti F, Ponte M, Vitale C, Maggi E, Romagnani S, Demarest J, Pantaleo J, Fauci AS, Moretta L: Human CD8+ T lymphocyte subsets that express HLA-class-I specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations Proc Natl Acad Sci USA, in press.
41. Semenzato G, Pandolfi F, Chisesi T, de Rossi G, Pizzolo G, Zambello R, Trentin L, Agostini C, Dim E, Vespignani M, Cafaro A, Pasqualetti D, Giubellino MC, Migone N, Foà R: The lymphoproliferative disease of granular lymphocytes A heterogeneous disorder ranging from indolent to aggressive conditions. Cancer 1987;60:2971-2978.
42. Oshimi K, Yamada O, Kaneko T, Nishmarita S, Lizuka Y, Urabe A, Inamon T, Asano S, Takahashi S, Hattori M, Naohara T, Ohira Y, Togawa A, Masuda Y, Okubo Y, Furusawa S, Sakamoto S, Omine M, Mori M, Tatsumi E, Mizogouchi H: Laboratory findings and clinical courses of 33 patients with granular lymphocyte-proliferative disorders. Leukemia 1993;7:782-788.
43. Zambello R, Trentin L, Ciccone E, Bulian P, Agostini C, Moretta A, Moretta L, Semenzato G. Phenotypic diversity of natural killer (NK) populations in patients with NK-type lymphoproliferative disease of granular lymphocytes. Blood 1993;81:2381-2385.
44. Cambiaggi A, Orengo AM, Meazza R, Sforzim S, Tazzari PL, Lauria F, Raspadori D, Zambello R, Semenzato G, Moretta L, Ferrmi S: The natural killer-related receptor for HLA-C expressed on T cells from CD3 + lymphoproliferative disease of granular lymphocytes display either inhibitory or stimulatory function Blood, in press.
45. Moretta A, Sivori S, Vitale M, Pende D, Morelli L, Augugliaro R, Bottino C, Moretta L: Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J Exp Med 1995;182:875-884.
46. Biassoni R, Cantoni C, Falco M, Verdiani S, Bottino C, Vitale M, Conte R, Poggi A, Moretta L: The HLA-C-specific 'activatory' or 'inhibitory' natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. J Exp Med, in press.
47. Cauda R, Coletti D, Lucia MB, Tumbarello M, Ruini C, Orengo AM, Moretta A: Analysis of natural killer cell subsets defined by the expression of two novel surface antigens (EB6 and GL183) in AIDS and AIDS-related conditions. Clin Immunol Immunopathol 1994;70:198-205.
48. Nakajima H, Tomiyama H, Takiguchi M: Inhibition of α/δ T cell recognition by receptors for MHC class I molecules. J Immunol 1995; 155:4139-4142.
49. Chadwick BS, Miller RG: Hybrid resistance in vitro: Possible role of both class I MHC and self peptides in determining the level of target cells sensitivity. J Immunol 1992;148:2307-2313.
50. Malnati MS, Peruzzi M, Parker KC, Biddison WE, Ciccone E, Moretta A, Long EO: Peptide specificity in the recognition of MHC class I by natural killer cell clones. Science 1995;267:1016-1018.
51. Kärre K: Express yourself or die: Peptides, MHC molecules, NK cells. Science 1995;267:978-979.