The anti-CD2 monoclonal antibody BTI-322 generates unresponsiveness by activation-associated T cell depletion

Clinical and Experimental Immunology

Volumn 138, Issue 3, 2004, Pages 476-483

  Xu, Yuanxin ^a,c,d   Kolber Simonds, D ^a   Hope, J A ^a   Bazin, H ^b   Latinne, D ^b   Monroy, R ^a   White Scharf, M E ^a   Schuurman, H J ^c  

^a BioTransplant Inc   (United States)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c Immerge Biotherapeutics Inc   (United States)

^d Genzyme   (United States)

Author keywords

CD2 antibodies; Cellular activation; Human T lymphocytes; Tolerance

Indexed keywords

CD2 ANTIGEN; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY BTI 322; MONOCLONAL ANTIBODY MEDI 407; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL INTERACTION; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; HAPLOTYPE; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE DEPLETION; MIXED LYMPHOCYTE REACTION; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; SWINE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS, CD3; CELL DIVISION; CELLS, CULTURED; EPITOPES; HUMANS; IMMUNE TOLERANCE; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; LYMPHOCYTE DEPLETION; MONOCYTES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SWINE; T-LYMPHOCYTES;

EID: 9644300793     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02650.x     Document Type: Article

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