Etoposide exposure during male mouse pachytene has complex effects on crossing-over and causes nondisjunction

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 565, Issue 1, 2004, Pages 61-77

  Russell, Liane B ^a   Hunsicker, Patricia R ^a   Kerley, Marilyn ^a   Pyle, April ^b   Saxton, Arnold M ^b  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Chromosome segregation; Etoposide; Germ cell stages; Meiosis; Mice; Nondisjunction; Recombination; Spermatogenesis; Topoisomerase II

Indexed keywords

DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTROMERE; CHROMOSOME 15; CHROMOSOME 7; CHROMOSOME 8; CHROMOSOME ANALYSIS; CHROMOSOME PAIRING; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CROSSING OVER; DRUG EFFECT; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC RECOMBINATION; GENOTOXICITY; MALE; MEIOSIS; MICROSATELLITE MARKER; MOUSE; NONDISJUNCTION; NONHUMAN; PACHYTENE; PRIORITY JOURNAL; PROGENY; SEX CHROMOSOME ABERRATION; SPERMATOCYTE; X CHROMOSOME; Y CHROMOSOME;

ANIMALS; CHROMOSOME ABERRATIONS; CHROMOSOMES; CROSSING OVER, GENETIC; ETOPOSIDE; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MICE; MICROSATELLITE REPEATS; NONDISJUNCTION, GENETIC; NUCLEIC ACID SYNTHESIS INHIBITORS; PACHYTENE STAGE; SPERMATOZOA;

EID: 9644291577     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2004.09.005     Document Type: Article

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