메뉴 건너뛰기




Volumn 11, Issue 4, 1996, Pages 315-325

Induction of somatic mutation and recombination by four inhibitors of eukaryotic topoisomerases assayed in the wing spot test of Drosophila melanogaster

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); ELLIPTICINE; EPIPODOPHYLLOTOXIN; ETOPOSIDE; ISOMERASE INHIBITOR; TENIPOSIDE;

EID: 0030037728     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/11.4.315     Document Type: Article
Times cited : (62)

References (60)
  • 1
    • 0028226564 scopus 로고
    • Etoposide (VP 16): Cytogenetic studies in mice
    • Agarwal, K., Mukherjee, A. and Sen, S. (1994) Etoposide (VP 16): cytogenetic studies in mice. Environ. Mol. Mutagen., 23, 190-193.
    • (1994) Environ. Mol. Mutagen. , vol.23 , pp. 190-193
    • Agarwal, K.1    Mukherjee, A.2    Sen, S.3
  • 2
    • 0000885080 scopus 로고
    • Mitotic recombination
    • Ashburner, M. and Novitski, E. (eds), Academic Press, London
    • Becker, H.J. (1976) Mitotic recombination. In Ashburner, M. and Novitski, E. (eds), The Genetics and Biology of Drosophila. Academic Press, London, vol. 1c, pp. 1020-1087.
    • (1976) The Genetics and Biology of Drosophila , vol.1 C , pp. 1020-1087
    • Becker, H.J.1
  • 3
    • 0015430498 scopus 로고
    • Cell cycle phase specificity and biochemical effects of ellipticine on mammalian cells
    • Bhuyan, B.K., Fraser, T.J. and Li, L.H. (1972) Cell cycle phase specificity and biochemical effects of ellipticine on mammalian cells. Cancer Res., 32, 2538-2544.
    • (1972) Cancer Res. , vol.32 , pp. 2538-2544
    • Bhuyan, B.K.1    Fraser, T.J.2    Li, L.H.3
  • 4
    • 0027166887 scopus 로고
    • Consequences of topoisomerase II inhibition in early embryogenesis of Drosophila revealed by in vivo confocal laser scanning microscopy
    • Buchenau, P., Saumweber, H. and Arndt-Jovin, D.J. (1993) Consequences of topoisomerase II inhibition in early embryogenesis of Drosophila revealed by in vivo confocal laser scanning microscopy. J. Cell Sci., 104, 1175-1185.
    • (1993) J. Cell Sci. , vol.104 , pp. 1175-1185
    • Buchenau, P.1    Saumweber, H.2    Arndt-Jovin, D.J.3
  • 5
    • 0021749639 scopus 로고
    • Non-intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II
    • Chen, G.L., Yang, L., Rowe, T.C., Halligan, B.D., Tewey, K.M. and Liu, L.F. (1984) Non-intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. J. Biol. Chem., 259, 13560-13566.
    • (1984) J. Biol. Chem. , vol.259 , pp. 13560-13566
    • Chen, G.L.1    Yang, L.2    Rowe, T.C.3    Halligan, B.D.4    Tewey, K.M.5    Liu, L.F.6
  • 6
    • 0023677626 scopus 로고
    • Somatic recombination and mutation assays in Drosophila: A comparison of the response of two different strains to four mutagens
    • Clements, J. and Vogel, E.W. (1988) Somatic recombination and mutation assays in Drosophila: a comparison of the response of two different strains to four mutagens. Mutat. Res., 209, 1-5.
    • (1988) Mutat. Res. , vol.209 , pp. 1-5
    • Clements, J.1    Vogel, E.W.2
  • 8
    • 0023403294 scopus 로고
    • Mutagenicity of m-AMSA and o-AMSA in mammalian cells due to clastogenic mechanism: Possible role of topoisomerase
    • DeMarini, D.M., Doerr, C.L., Meyer, M.K., Brock, K.H., Hozier, J. and Moore, M.M. (1987b) Mutagenicity of m-AMSA and o-AMSA in mammalian cells due to clastogenic mechanism: possible role of topoisomerase. Mutagenesis, 2, 349-355.
    • (1987) Mutagenesis , vol.2 , pp. 349-355
    • DeMarini, D.M.1    Doerr, C.L.2    Meyer, M.K.3    Brock, K.H.4    Hozier, J.5    Moore, M.M.6
  • 9
    • 0023155751 scopus 로고
    • Cell cycle dependence of sister chromatid exchange induction by DNA topoisomerase II inhibitors in Chinese hamster V79 cells
    • Dillehay, L.E., Denstman, S.C. and Williams, J.R. (1987) Cell cycle dependence of sister chromatid exchange induction by DNA topoisomerase II inhibitors in Chinese hamster V79 cells. Cancer Res., 47, 206-209.
    • (1987) Cancer Res. , vol.47 , pp. 206-209
    • Dillehay, L.E.1    Denstman, S.C.2    Williams, J.R.3
  • 10
    • 0028661136 scopus 로고
    • Topoisomerase II enzymes and mutagenicity
    • Ferguson, L.R. and Baguley, B.C. (1994) Topoisomerase II enzymes and mutagenicity. Environ. Mol. Mutagen., 24, 245-261.
    • (1994) Environ. Mol. Mutagen. , vol.24 , pp. 245-261
    • Ferguson, L.R.1    Baguley, B.C.2
  • 11
    • 0023863353 scopus 로고
    • Mitotic crossing-over by anticancer drugs in Saccharomyces cerevisiae strain D5
    • Ferguson, L.R. and Turner, P.M. (1988) Mitotic crossing-over by anticancer drugs in Saccharomyces cerevisiae strain D5. Mutat. Res., 204, 239-249.
    • (1988) Mutat. Res. , vol.204 , pp. 239-249
    • Ferguson, L.R.1    Turner, P.M.2
  • 12
    • 0027430332 scopus 로고
    • Induction of mitotic crossing-over by the topoisomerase II poison DACA (N-[2-dimethylaminoethyl]acridine-4-carboxamide) in Saccharomyces cerevisiae
    • Ferguson, L.R., Turner, P.M. and Baguley, B.C. (1993) Induction of mitotic crossing-over by the topoisomerase II poison DACA (N-[2-dimethylaminoethyl]acridine-4-carboxamide) in Saccharomyces cerevisiae. Mutat. Res., 289, 157-163.
    • (1993) Mutat. Res. , vol.289 , pp. 157-163
    • Ferguson, L.R.1    Turner, P.M.2    Baguley, B.C.3
  • 13
    • 0023751542 scopus 로고
    • Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative, or inconclusive result
    • Frei, H. and Würgler, F.E. (1988) Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative, or inconclusive result. Mutat. Res., 203, 297-308.
    • (1988) Mutat. Res. , vol.203 , pp. 297-308
    • Frei, H.1    Würgler, F.E.2
  • 14
    • 0028925446 scopus 로고
    • Optimal experimental design and sample size for the statistical evaluation of data from somatic mutation and recombination tests (SMART) in Drosophila
    • Frei, H. and Würgler, F.E. (1995) Optimal experimental design and sample size for the statistical evaluation of data from somatic mutation and recombination tests (SMART) in Drosophila. Mutat. Res., 334, 247-258.
    • (1995) Mutat. Res. , vol.334 , pp. 247-258
    • Frei, H.1    Würgler, F.E.2
  • 15
    • 0021688314 scopus 로고
    • Aristolochic acid is mutagenic and recombinogenic in Drosophila genotoxicity tests
    • Frei, H., Würgler, F.E., Juon, H., Hall, C.B. and Graf, U. (1985) Aristolochic acid is mutagenic and recombinogenic in Drosophila genotoxicity tests. Arch. Toxicol., 56, 158-166.
    • (1985) Arch. Toxicol. , vol.56 , pp. 158-166
    • Frei, H.1    Würgler, F.E.2    Juon, H.3    Hall, C.B.4    Graf, U.5
  • 16
    • 0026503556 scopus 로고
    • The genotoxicity of the anti-cancer drug mitoxantrone in somatic and germ cells of Drosophila melanogaster
    • Frei, H., Clements, J., Howe, D. and Würgler, F.E. (1992a) The genotoxicity of the anti-cancer drug mitoxantrone in somatic and germ cells of Drosophila melanogaster. Mutat. Res., 279, 21-33.
    • (1992) Mutat. Res. , vol.279 , pp. 21-33
    • Frei, H.1    Clements, J.2    Howe, D.3    Würgler, F.E.4
  • 17
    • 0026755334 scopus 로고
    • Structure/activity relationships of the genotoxic potencies of sixteen pyrrolizidine alkaloids assayed for the induction of somatic mutation and recombination in wing cells of Drosophila melanogaster
    • Frei, H., Lüthy, J., Brauchli, J., Zweifel, U., Würgler, F.E. and Schlatter, C. (1992b) Structure/activity relationships of the genotoxic potencies of sixteen pyrrolizidine alkaloids assayed for the induction of somatic mutation and recombination in wing cells of Drosophila melanogaster. Chem.-Biol. Interact., 83, 1-22.
    • (1992) Chem.-Biol. Interact. , vol.83 , pp. 1-22
    • Frei, H.1    Lüthy, J.2    Brauchli, J.3    Zweifel, U.4    Würgler, F.E.5    Schlatter, C.6
  • 18
    • 0021799944 scopus 로고
    • Action of camptothecin and its derivatives on deoxyribonucleic acid
    • Fukada, M. (1985) Action of camptothecin and its derivatives on deoxyribonucleic acid. Biochem. Pharmacol., 34, 1225-1230.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 1225-1230
    • Fukada, M.1
  • 19
    • 0025829092 scopus 로고
    • Mechanism of quinolone mutagenicity in bacteria
    • Gocke, E. (1991) Mechanism of quinolone mutagenicity in bacteria. Mutat. Res., 248, 135-143.
    • (1991) Mutat. Res. , vol.248 , pp. 135-143
    • Gocke, E.1
  • 21
    • 0026548137 scopus 로고
    • The genotoxicity of chromium(VI) oxide in the wing spot test of Drosophila melanogaster is over 90% due to mitotic recombination
    • Graf, U., Ok-Soon, H. and Olvera Ramirez, O. (1992) The genotoxicity of chromium(VI) oxide in the wing spot test of Drosophila melanogaster is over 90% due to mitotic recombination. Mutat. Res., 266, 197-203.
    • (1992) Mutat. Res. , vol.266 , pp. 197-203
    • Graf, U.1    Ok-Soon, H.2    Olvera Ramirez, O.3
  • 22
    • 0025022580 scopus 로고
    • Tests for the genotoxicity of m-AMSA, etoposide, teniposide and ellipticine in Neurospora crassa
    • Gupta, R. (1990) Tests for the genotoxicity of m-AMSA, etoposide, teniposide and ellipticine in Neurospora crassa. Mutat. Res., 240, 47-58.
    • (1990) Mutat. Res. , vol.240 , pp. 47-58
    • Gupta, R.1
  • 23
    • 0023251854 scopus 로고
    • Etoposide (VP16) and teniposide (VM26): Novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems
    • Gupta, R.S., Bromke, A., Bryant, D.W., Gupta, R., Singh, B. and McCalla, D.R. (1987) Etoposide (VP16) and teniposide (VM26): novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems. Mutagenesis, 2, 179-186.
    • (1987) Mutagenesis , vol.2 , pp. 179-186
    • Gupta, R.S.1    Bromke, A.2    Bryant, D.W.3    Gupta, R.4    Singh, B.5    McCalla, D.R.6
  • 24
    • 0017670117 scopus 로고
    • The effects of X-rays on the proliferation dynamics of cells in the imaginal wing disc of Drosophila melanogaster
    • Haynie, J.L. and Bryant, P.J. (1977) The effects of X-rays on the proliferation dynamics of cells in the imaginal wing disc of Drosophila melanogaster. Wilh. Roux Arch. Develop. Biol., 183, 85-100.
    • (1977) Wilh. Roux Arch. Develop. Biol. , vol.183 , pp. 85-100
    • Haynie, J.L.1    Bryant, P.J.2
  • 25
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang, Y.-H., Hertzberg, R., Hecht, S. and Liu, L.F. (1985) Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem., 260, 14873-14878.
    • (1985) J. Biol. Chem. , vol.260 , pp. 14873-14878
    • Hsiang, Y.-H.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 26
    • 0027102355 scopus 로고
    • Isolation and characterization of a gene encoding DNA topoisomerase I in Drosophila melanogaster
    • Hsieh, T.-S., Brown, S.D., Huang, P. and Fostel, J. (1992) Isolation and characterization of a gene encoding DNA topoisomerase I in Drosophila melanogaster. Nucleic Acids Res., 20, 6177-6182.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 6177-6182
    • Hsieh, T.-S.1    Brown, S.D.2    Huang, P.3    Fostel, J.4
  • 27
    • 0015714946 scopus 로고
    • Effects of a new antitumor agent, epipodophyllotoxin, on growth and chromosomes in human hematopoietic cell lines
    • Huang, C.C., Hou, Y. and Wang, J.J. (1973) Effects of a new antitumor agent, epipodophyllotoxin, on growth and chromosomes in human hematopoietic cell lines. Cancer Res., 33, 3123-3129.
    • (1973) Cancer Res. , vol.33 , pp. 3123-3129
    • Huang, C.C.1    Hou, Y.2    Wang, J.J.3
  • 28
    • 0022538665 scopus 로고
    • Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase a primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts
    • Hussy, P., Maass, G., Tümmler, B., Grosse, F. and Schomburg, U. (1986) Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase a primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts. Antimicrob. Agents Chemother., 29, 1073-1078.
    • (1986) Antimicrob. Agents Chemother. , vol.29 , pp. 1073-1078
    • Hussy, P.1    Maass, G.2    Tümmler, B.3    Grosse, F.4    Schomburg, U.5
  • 29
    • 0024431084 scopus 로고
    • Interaction of topoisomerase I with the transcribed region of the Drosophila HSP 70 heat shock gene
    • Kroeger, P.E. and Rowe, T.C. (1989) Interaction of topoisomerase I with the transcribed region of the Drosophila HSP 70 heat shock gene. Nucleic Acids Res., 17, 8495-8509.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 8495-8509
    • Kroeger, P.E.1    Rowe, T.C.2
  • 32
    • 0024316466 scopus 로고
    • DNA topoisomerase poisons as antitumor drugs
    • Liu, L.F. (1989) DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem., 58, 351-375.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 351-375
    • Liu, L.F.1
  • 33
    • 0025222615 scopus 로고
    • Chromosome aberrations induced by etoposide (VP-16) are not random
    • Maraschin, J., Dutrillaux, B. and Aurias, A. (1990) Chromosome aberrations induced by etoposide (VP-16) are not random. Int. J. Cancer, 46, 808-812.
    • (1990) Int. J. Cancer , vol.46 , pp. 808-812
    • Maraschin, J.1    Dutrillaux, B.2    Aurias, A.3
  • 34
    • 0020554926 scopus 로고
    • Evidence that mAMSA induces lopoisomerase action
    • Marshall, B., Darkin, S. and Ralph, R.K. (1983) Evidence that mAMSA induces lopoisomerase action. FEBS Lett., 161, 75-78.
    • (1983) FEBS Lett. , vol.161 , pp. 75-78
    • Marshall, B.1    Darkin, S.2    Ralph, R.K.3
  • 35
    • 0018878838 scopus 로고
    • Non-mutagenic genotoxicants: Novobiocin and nalidixic acid, 2 inhibitors of DNA gyrase
    • McCoy, E., Petrullo, L.A. and Rosenkranz, H.S. (1980) Non-mutagenic genotoxicants: novobiocin and nalidixic acid, 2 inhibitors of DNA gyrase. Mutat. Res., 79, 33-43.
    • (1980) Mutat. Res. , vol.79 , pp. 33-43
    • McCoy, E.1    Petrullo, L.A.2    Rosenkranz, H.S.3
  • 37
    • 0022515776 scopus 로고
    • Mutagenicity tests of etoposide and teniposide
    • Nakanomyo, H., Hiraoka, M. and Shiraya, M. (1986) Mutagenicity tests of etoposide and teniposide. J. Toxicol. Sci., 11(Suppl. I), 301-310.
    • (1986) J. Toxicol. Sci. , vol.11 , Issue.1 SUPPL. , pp. 301-310
    • Nakanomyo, H.1    Hiraoka, M.2    Shiraya, M.3
  • 38
    • 0000536643 scopus 로고
    • DNA topoisomerase-targeting antitumor drugs can be studied in yeast
    • Nitiss, J. and Wang, J.C. (1988) DNA topoisomerase-targeting antitumor drugs can be studied in yeast. Proc. Natl. Acad. Sci. USA, 85, 7501-7505.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 7501-7505
    • Nitiss, J.1    Wang, J.C.2
  • 39
    • 0024592815 scopus 로고
    • Biochemical basis for the interactions of type I and type II topoisomerases with DNA
    • Osheroff, N. (1989a) Biochemical basis for the interactions of type I and type II topoisomerases with DNA. Pharmacol. Ther., 41, 223-241.
    • (1989) Pharmacol. Ther. , vol.41 , pp. 223-241
    • Osheroff, N.1
  • 40
    • 0024395605 scopus 로고
    • Effect of antineoplastic agents on the DNA cleavage/ religation reaction of eukaryotic topoisomerase II: Inhibition of DNA religation by etoposide
    • Osheroff, N. (1989b) Effect of antineoplastic agents on the DNA cleavage/ religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide. Biochemistry, 28, 6157-6160.
    • (1989) Biochemistry , vol.28 , pp. 6157-6160
    • Osheroff, N.1
  • 41
    • 0027465298 scopus 로고
    • Evaluation of genotoxicity of the indenoisoquinoline analogues of fagaronine and nitidine in Drosophila melanogaster
    • Pérez-Chiesa, Y. and Narvaez, Z. (1993) Evaluation of genotoxicity of the indenoisoquinoline analogues of fagaronine and nitidine in Drosophila melanogaster. Mutat. Res., 301, 207-212.
    • (1993) Mutat. Res. , vol.301 , pp. 207-212
    • Pérez-Chiesa, Y.1    Narvaez, Z.2
  • 42
    • 0027535727 scopus 로고
    • Absence of mutagenicity of benzo[c]phenantridine alkaloids in somatic cells of Drosophila melanogaster: Comparison with 7,12-dimethylbenz[a]anthracene and chrysene
    • Pérez-Chiesa, Y. and Rodríguez, A. (1993) Absence of mutagenicity of benzo[c]phenantridine alkaloids in somatic cells of Drosophila melanogaster: comparison with 7,12-dimethylbenz[a]anthracene and chrysene. Mutat. Res., 298, 277-283.
    • (1993) Mutat. Res. , vol.298 , pp. 277-283
    • Pérez-Chiesa, Y.1    Rodríguez, A.2
  • 43
    • 0020698654 scopus 로고
    • Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenantridine (fagaronine), with nucleic acids
    • Pezzuto, J.M., Antosiak, S.K., Messmer, W.M., Slaytor, M.B. and Honig, G.R. (1983) Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenantridine (fagaronine), with nucleic acids. Chem.-Biol. Interact., 43, 323-339.
    • (1983) Chem.-Biol. Interact. , vol.43 , pp. 323-339
    • Pezzuto, J.M.1    Antosiak, S.K.2    Messmer, W.M.3    Slaytor, M.B.4    Honig, G.R.5
  • 44
    • 0021153767 scopus 로고
    • Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents
    • Pommier, Y., Schwartz, R.E., Kohn, K.W. and Zwelling, L.A. (1984) Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents. Biochemistry, 23, 3194-3201.
    • (1984) Biochemistry , vol.23 , pp. 3194-3201
    • Pommier, Y.1    Schwartz, R.E.2    Kohn, K.W.3    Zwelling, L.A.4
  • 46
    • 0026519925 scopus 로고
    • Modulation of genotoxicity in Drosophila
    • Ramel, C. and Magnusson, J. (1992) Modulation of genotoxicity in Drosophila. Mutat. Res., 267, 221-227.
    • (1992) Mutat. Res. , vol.267 , pp. 221-227
    • Ramel, C.1    Magnusson, J.2
  • 47
    • 0027172883 scopus 로고
    • Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: Evidence for distinct drug interaction domains on topoisomerase II
    • Robinson, M.J., Corbett, A.H. and Osheroff, N. (1993) Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II. Biochemistry, 32, 3638-3643.
    • (1993) Biochemistry , vol.32 , pp. 3638-3643
    • Robinson, M.J.1    Corbett, A.H.2    Osheroff, N.3
  • 48
    • 0021099843 scopus 로고
    • DNA topoisomerase II from Drosophila melanogaster; purification and physical characterization
    • Shelton, E.R., Osheroff, N. and Brutlag, D.L. (1983) DNA topoisomerase II from Drosophila melanogaster; purification and physical characterization. J. Biol. Chem., 258, 9530-9535.
    • (1983) J. Biol. Chem. , vol.258 , pp. 9530-9535
    • Shelton, E.R.1    Osheroff, N.2    Brutlag, D.L.3
  • 49
    • 0020698387 scopus 로고
    • Testing the mutagenicity of malondialdehyde and formaldehyde by the Drosophila mosaic and the sex-linked recessive lethal tests
    • Szabad, J., Soós, I., Polgár, G. and Héjja, G. (1983) Testing the mutagenicity of malondialdehyde and formaldehyde by the Drosophila mosaic and the sex-linked recessive lethal tests. Mutat. Res., 113, 117-133.
    • (1983) Mutat. Res. , vol.113 , pp. 117-133
    • Szabad, J.1    Soós, I.2    Polgár, G.3    Héjja, G.4
  • 50
    • 0022405604 scopus 로고
    • Effect of novobiocin on the frequencies of chromatid-type aberrations and sister-chromatid exchanges following gamma-irradiation
    • Takahashi, K., Kaneko, I., Nishiyama, C. and Nakano, K. (1985) Effect of novobiocin on the frequencies of chromatid-type aberrations and sister-chromatid exchanges following gamma-irradiation. Mutat. Res., 144, 265-270.
    • (1985) Mutat. Res. , vol.144 , pp. 265-270
    • Takahashi, K.1    Kaneko, I.2    Nishiyama, C.3    Nakano, K.4
  • 51
    • 0022634984 scopus 로고
    • Increase in the frequency of γ-ray induced chromosomal aberrations in mammalian cells by post-treatment with novobiocin
    • Takahashi, K., Kaneko, I. and Nishiyama, C. (1986) Increase in the frequency of γ-ray induced chromosomal aberrations in mammalian cells by post-treatment with novobiocin. Int. J. Radiat. Biol., 49, 657-663.
    • (1986) Int. J. Radiat. Biol. , vol.49 , pp. 657-663
    • Takahashi, K.1    Kaneko, I.2    Nishiyama, C.3
  • 52
    • 0027534655 scopus 로고
    • Performance of 181 chemicals in a Drosophila assay predominantly monitoring interchromosomal mitotic recombination
    • Vogel, E.W. and Nivard, M.J.M. (1993) Performance of 181 chemicals in a Drosophila assay predominantly monitoring interchromosomal mitotic recombination. Mutagenesis, 8, 57-81.
    • (1993) Mutagenesis , vol.8 , pp. 57-81
    • Vogel, E.W.1    Nivard, M.J.M.2
  • 53
    • 0027433723 scopus 로고
    • Inhibition of topoisomerase I function by nitidine and fagaronine
    • Wang, L.-K., Johnson, R.K. and Hecht, S.M. (1993) Inhibition of topoisomerase I function by nitidine and fagaronine. Chem. Res. Toxicol., 6, 813-818.
    • (1993) Chem. Res. Toxicol. , vol.6 , pp. 813-818
    • Wang, L.-K.1    Johnson, R.K.2    Hecht, S.M.3
  • 54
    • 0024512460 scopus 로고
    • The level of Z-DNA in metabolically active, permeabilized mammalian cell nuclei is regulated by torsional strain
    • Wittig, B., Dorbic, T. and Rich, A. (1989) The level of Z-DNA in metabolically active, permeabilized mammalian cell nuclei is regulated by torsional strain. J. Cell Biol., 108, 755-764.
    • (1989) J. Cell Biol. , vol.108 , pp. 755-764
    • Wittig, B.1    Dorbic, T.2    Rich, A.3
  • 55
    • 0022607863 scopus 로고
    • In vivo mutagenicity testing using cells of Drosophila melanogaster
    • De Serres, F.J. (ed.), Plenum Press, New York
    • Würgler, F.E. and Vogel, E.W. (1986) In vivo mutagenicity testing using cells of Drosophila melanogaster. In De Serres, F.J. (ed.), Chemical Mutagens, Principles and Methods far their Detection. Plenum Press, New York, vol. 10, pp. 1-72.
    • (1986) Chemical Mutagens, Principles and Methods Far Their Detection , vol.10 , pp. 1-72
    • Würgler, F.E.1    Vogel, E.W.2
  • 56
    • 0024499288 scopus 로고
    • Structure of the Drosophila DNA topoisomerase II gene; nucleotide sequence and homology among topoisomerases II
    • Wyckoff, E., Natalie, D., Nolan, J.M., Lee, M. and Hsieh, T.-S. (1989) Structure of the Drosophila DNA topoisomerase II gene; nucleotide sequence and homology among topoisomerases II. J. Mol. Biol., 205, 1-13.
    • (1989) J. Mol. Biol. , vol.205 , pp. 1-13
    • Wyckoff, E.1    Natalie, D.2    Nolan, J.M.3    Lee, M.4    Hsieh, T.-S.5
  • 57
    • 0023958908 scopus 로고
    • Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes
    • Zhang, H., Wang, J.C. and Liu, L.F. (1988) Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes. Proc. Natl. Acad. Sci. USA, 85, 1060-1064.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1060-1064
    • Zhang, H.1    Wang, J.C.2    Liu, L.F.3
  • 58
    • 0025370560 scopus 로고
    • A concerted approach to the study of aneuploidogenic properties of two chelating agents (EDTA and NTA) in the germ and somatic cell lines of Drosophila and the mouse
    • Zordan, M., Russo, A., Costa, R., Bianco, N., Beltrame, C. and Levis, A.G. (1990) A concerted approach to the study of aneuploidogenic properties of two chelating agents (EDTA and NTA) in the germ and somatic cell lines of Drosophila and the mouse. Environ. Mol. Mutagen., 15, 205-213.
    • (1990) Environ. Mol. Mutagen. , vol.15 , pp. 205-213
    • Zordan, M.1    Russo, A.2    Costa, R.3    Bianco, N.4    Beltrame, C.5    Levis, A.G.6
  • 59
    • 0026023014 scopus 로고
    • The genotoxicity of nitrilotriacetic acid (NTA) in a somatic mutation and recombination test in Drosophila melanogaster
    • Zordan, M., Graf, U., Singer, D., Beltrame, C., Dalla Valle, L., Osti, M., Costa, R. and Levis, A.G. (1991) The genotoxicity of nitrilotriacetic acid (NTA) in a somatic mutation and recombination test in Drosophila melanogaster. Mutat. Res., 262, 253-261.
    • (1991) Mutat. Res. , vol.262 , pp. 253-261
    • Zordan, M.1    Graf, U.2    Singer, D.3    Beltrame, C.4    Dalla Valle, L.5    Osti, M.6    Costa, R.7    Levis, A.G.8
  • 60
    • 0027994248 scopus 로고
    • Chloral hydrate is recombinogenic in the wing spot test in Drosophila melanogaster
    • Zordan, M., Osti, M., Pesce, M. and Costa, R. (1994) Chloral hydrate is recombinogenic in the wing spot test in Drosophila melanogaster. Mutat. Res., 322, 111-116.
    • (1994) Mutat. Res. , vol.322 , pp. 111-116
    • Zordan, M.1    Osti, M.2    Pesce, M.3    Costa, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.