Apoptotic topoisomerase I-DNA complexes induced by oxygen radicals and mitochondrial dysfunction

Cell Cycle

Volumn 3, Issue 9, 2004, Pages 1093-1095

  Sordet, Olivier ^a   Khan, Qasim A ^a   Pommier, Yves ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Apoptosis; Arsenic trioxide; DNA fragmentation; Etoposide; Mitochondria; Oxidative DNA lesions; Reative oxygen species; Staurosporine; Top1 cleavage complexes; Topoisomerase I

Indexed keywords

APOPTOSIS INDUCING FACTOR; ARSENIC TRIOXIDE; DNA FRAGMENT; DNA TOPOISOMERASE; ETOPOSIDE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE; STAUROSPORINE;

APOPTOSIS; CELL CYCLE; CHROMATIN; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA CLEAVAGE; DNA DAMAGE; DNA PROTEIN COMPLEX; DNA REPLICATION; DNA SUPERCOILING; MITOCHONDRIAL DYSFUNCTION; MOLECULAR MECHANICS; PROTEIN EXPRESSION; REVIEW; TRANSCRIPTION REGULATION;

EID: 9644275563     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.3.9.1086     Document Type: Review

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