New strategy for the synthesis of 3′,5′-bifunctionalized oligonucleotide conjugates through sequential formation of chemoselective oxime bonds

Chemistry - A European Journal

Volumn 10, Issue 23, 2004, Pages 5988-5995

  Edupuganti, Om Prakash ^a   Singh, Yashveer ^a   Defrancq, Eric ^a   Dumy, Pascal ^a  

^a UNIVERSITÉ JOSEPH FOURIER   (France)

Author keywords

Chemoselectivity; Conjugation; DNA; Oligonucleotides; Oxime; Peptides

Indexed keywords

APPROXIMATION THEORY; CHEMICAL BONDS; FUNCTIONS; REACTION KINETICS;

AMINOOXY FUNCTIONALITY; CONJUGATION; MILD AQUEOUS CONDITIONS; OLIGONUCLEOTIDE;

SYNTHESIS (CHEMICAL);

ALDEHYDE; OLIGONUCLEOTIDE; OXIME; PEPTIDE DERIVATIVE; PEPTIDE OLIGONUCLEOTIDE CONJUGATE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL BOND; DRUG CONJUGATION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ALDEHYDES; FLUORESCENT DYES; MOLECULAR STRUCTURE; OLIGONUCLEOTIDES; OXIMES; PEPTIDES;

EID: 9644266960     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/chem.200400390     Document Type: Article

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