Synthesis of chiral macrocycles by cyclodimerization of diamines with stepwise nucleophilic aromatic substitution of 1,5-difluoro-2,4-dinitrobenzene

Synlett

Volumn , Issue 14, 2004, Pages 2517-2520

  Toftered, Jörgen ^a   Nilsson, Ulf J ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Chiral; Cyclophanes; Diazapyrene; Macrocycles; Nucleophilic aromatic substitution

Indexed keywords

1,5 DIFLUORO 2,4 DINITROBENZENE; 2,7 DIAZA 1,2,3,6,7,8 HEXAHYDROPYRENE; AMINO ACID DERIVATIVE; AROMATIC COMPOUND; CYCLOPHANE DERIVATIVE; DIAMINE DERIVATIVE; HETEROCYCLIC COMPOUND; MACROCYCLIC COMPOUND; NITROBENZENE DERIVATIVE; PYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; BINDING SITE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; CONFORMATIONAL TRANSITION; CYCLIZATION; DEPROTECTION REACTION; DIMERIZATION; MOLECULAR RECOGNITION; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLUBILITY; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; SUPRAMOLECULAR CHEMISTRY; SYNTHESIS; TECHNIQUE; TEMPERATURE DEPENDENCE;

EID: 9644266675     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-835633     Document Type: Article

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