Noninvasive breath tests can detect alterations in gastric emptying in the mouse

European Journal of Clinical Investigation

Volumn 32, Issue 5, 2002, Pages 341-344

  Symonds, Erin ^a,b   Butler, R ^a,b   Omari, T ^a  

^a WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

13C acetic acid; 13C octanoic acid; Breath test; Erythromycin; Gastric emptying; Motility

Indexed keywords

ACETIC ACID; CARBON DIOXIDE; ERYTHROMYCIN; HYDROXYPROPYLMETHYLCELLULOSE; OCTANOIC ACID; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BREATH ANALYSIS; CARBON DIOXIDE MEASUREMENT; CONTROLLED STUDY; DRUG SCREENING; FEMALE; GASTROINTESTINAL MOTILITY; MEAL; MOUSE; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; STOMACH EMPTYING;

ANIMALS; BREATH TESTS; CARBON DIOXIDE; CARBON RADIOISOTOPES; FEMALE; GASTRIC EMPTYING; MICE; MODELS, ANIMAL; TIME FACTORS;

EID: 0037002875     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2002.00991.x     Document Type: Article

References (20)

1. *C]octanoic acid breath test to measure gastric emptying rate of solids. Dig Dis Sci 1994;39:104S-106S.
2. Maes B, Mys G, Geypens B, Evenepoel P, Ghoos Y, Rutgeerts P. Gastric emptying flow curves separated from carbon-labeled octanoic acid breath test results. Am J Physiol 1998;275:G169-G175.
3. Ghoos Y, Maes B, Geypens B, Mys G, Hiele M, Rhutgeerts P et al. Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. Gastroenterol 1993;104:1640-7.
4. 13C] acetate breath test. Dig Dis Sci 1994;39:107S-109S.
5. 13C breath tests. Dig Dis Sci 1995;40:2200-6.
6. Maes B, Ghoos Y, Geypens B, Mys G, Hiele M, Rutgeerts P et al. Combined carbon-13-glycine/carbon-14-octanoic acid breath test to monitor gastric emptying rates of liquids and solids. J Nucl Med 1994;35:824-31.
7. 13C]-octanoic acid breath test. Clin Exp Pharmacol Physiol 2000;27:671-5.
8. Reppas C, Meyer J, Sirios P, Dressman J. Effect of hydroxypropylmethylcellulose on gastrointestinal transit and luminal viscosity in dogs. Gastroenterol 1991;100:1217-23.
9. Sirios P, Amidon G, Meyer J, Doty J, Dressman J. Gastric emptying of non-digestible solids in dogs: a hydrodynamic correlation. Am J Physiol 1990;258:G65-G72.
10. Playford R, Floyd D, Macdonald C, Calnan D, Adeneken O, Johnson W et al. Bovine colostrum is a health food supplement which prevents NSAID induced gut damage. Gut 1999;44:653-8.
11. Reppas C, Eleftheriou G, Macheras P, Symillides M, Greenwood D, Dressman J. The effect of HPMC - a cholesterol lowering agent - on oral drug absorption in dogs. Biopharm Drug Dispos 1998;19:523-30.
12. Maes B, Hiele M, Geypens B, Ghoos Y, Vantrappen G. Pharmacological modulation of gastric emptying rate of solids as measured by the carbon labelled octanoic acid breath test: influence of erythromycin and propantheline. Gut 1994;35:333-7.
13. Minocha A, Katragadda R, Rahal P, Ries A. Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. Aliment Pharmacol Ther 1995;9:529-33.
14. Kuo W, Wadwa K, Ferris C. Cephalosporin antibiotics accelerate gastric emptying in mice. Dig Dis Sci 1998;43:1690-4.
15. Desai K, Sato R, Schauble E, Barsh G, Kobilka B, Bernstein D. Cardiovascular indexes in the mouse at rest and with exercise: new tools to study models of cardiac disease. Am J Physiol 1997;272:H1053-H1061.
16. Ehrlein H, Prove J. Effect of viscosity of test meals on gastric emptying in dogs. Q J Exp Physiol 1982;67:419-25.
17. Russell J, Bass P. Canine gastric emptying of fiber meals: influence of meal viscosity and antroduodenal motility. Am J Physiol 1985;249:G662-7.
18. Schemann M, Ehrlein H. The utility of cellulose meals for studies on gastrointestinal motility in dogs. Digestion 1982;25:194-6.
19. Janssens J, Peeters T, Vantrappen G, Tack J, Urbain J, De Roo M et al. Improvement of gastric emptying in diabetic gastroparesis by erythromycin. N Engl J Med 1990;322:108-31.
20. Richards R, Davenport K, Mc Callum R. The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. Am J Physiol 1993;88:203-7.