Radioiodine and 211At-labeled guanidinomethyl halobenzoyl octreotate conjugates: Potential peptide radiotherapeutics for somatostatin receptor-positive cancers

Peptides

Volumn 25, Issue 12, 2004, Pages 2087-2097

  Vaidyanathan, Ganesan ^a   Boskovitz, Abraham ^a   Shankar, Sriram ^a   Zalutsky, Michael R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Astatine 211; Externalization; Glu TOCA (N (1 deoxy d fructosyl) Tyr 3 octreotate); Internalization; Medulloblastoma; Octreotate; Octreotide; Radiotherapy; SSTR (somatostatin receptor)

Indexed keywords

ASTATINE 211; N (3 ASTATO 4 GUANIDINOMETHYLBENZOYL) 1 PHENYLALANYLOCTREOTATE AT 211; N (4 GUANIDINOMETHYL 3 IODOBENZOYL) 1 PHENYLALANYLOCTREOTATE; N (4 GUANIDINOMETHYL 3 IODOBENZOYL) 1 PHENYLALANYLOCTREOTATE I 125; N (4 GUANIDINOMETHYL 3 IODOBENZOYL) 1 PHENYLALANYLOCTREOTATE I 131; NALPHA (1 DEOXY DEXTRO FRUCTOSYL)IODINE 3 TYROSYLOCTREOTATE I 125; NALPHA (1 DEOXY DEXTRO FRUCTOSYL)IODINE 3 TYROSYLOCTREOTATE I 131; OCTREOTIDE; PHENYLALANINE DERIVATIVE; RADIOACTIVE IODINE; RADIOACTIVE MATERIAL; SOMATOSTATIN RECEPTOR; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; ASTATINE; CYCLOPEPTIDE; OCTREOTATE, N (4 GUANIDINOMETHYL 3 IODOBENZOYL) PHE(1); OCTREOTATE, N-(4-GUANIDINOMETHYL-3-IODOBENZOYL)-PHE(1)-;

ALPHA RADIATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG UPTAKE; LIVER; MEDULLOBLASTOMA; NONHUMAN; PRIORITY JOURNAL; RADIOCHEMISTRY; RAT; RECEPTOR BINDING; SCATCHARD PLOT; TUMOR CELL LINE; TUMOR XENOGRAFT; ANIMAL; CANCER TRANSPLANTATION; HUMAN; METABOLISM; MOUSE; NUDE MOUSE; PANCREAS TUMOR; SYNTHESIS; TISSUE DISTRIBUTION; XENOGRAFT;

MURINAE;

ANIMALS; ASTATINE; CELL LINE, TUMOR; HUMANS; IODINE RADIOISOTOPES; MEDULLOBLASTOMA; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; PEPTIDES, CYCLIC; RATS; RECEPTORS, SOMATOSTATIN; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 9644262691     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2004.08.018     Document Type: Article

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