Synthetic studies towards anti-SARS agents: Application of an indium-mediated allylation of α-aminoaldehydes as the key step towards an intermediate

Tetrahedron Letters

Volumn 45, Issue 52, 2004, Pages 9501-9504

  Chng, Shu Sin ^a   Hoang, Truong Giang ^a   Wayne Lee, Wei Woon ^a   Tham, Mun Pun ^a   Ling, Hui Yvonne ^a   Loh, Teck Peng ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

AG7088; Anti SARS agents; Diastereoselective; Indium mediated allylation

Indexed keywords

AMINOALDEHYDE; ANTIVIRUS AGENT; INDIUM; PROTEINASE INHIBITOR; RUPINTRIVIR;

ALLYLATION; ARTICLE; CHEMICAL MODIFICATION; DRUG BIOAVAILABILITY; DRUG SYNTHESIS; ENZYME INHIBITION; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; STEREOCHEMISTRY;

SARS CORONAVIRUS;

EID: 9644259256     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.10.146     Document Type: Article

References (14)

1. World Health Organisation, 'Cumulative Number of Reported Probable Cases of SARS', http://www.who.int/csr/sars/country/en/
2. Centre for Disease Control and Prevention, 'Severe Acute Respiratory Syndrome', http://www.cdc.gov/ncidod/sars/
3. T.G. Ksiazek, D. Erdman, C.S. Goldsmith, S.R. Zaki, T. Peret, S. Emery, S. Tong, C. Urbani, J.A. Comer, W. Lim, P.E. Rollin, S.F. Dowell, A.E. Ling, C.D. Humphrey, W.J. Shieh, J. Guarner, C.D. Paddock, P. Rota, B. Fields, J. DeRisi, J.Y. Yang, N. Cox, J.M. Hughes, J.W. LeDuc, W.J. Bellini, and L.J. Anderson New Engl. J. Med. 348 2003 1953 1966
4. C. Drosten, S. Günther, W. Preiser, S. Werf, H.R. Brodt, S. Becker, H. Rabenau, M. Panning, L. Kolesnikova, R.A.M. Fouchier, A. Berger, A.M. Burguière, J. Cinatl, M. Eickmann, N. Escriou, K. Grywna, S. Kramme, J.C. Manuguerra, S. Müller, V. Rickerts, M. Stürmer, S. Vieth, H.D. Klenk, A.D.M.E. Osterhaus, H. Schmitz, and H.W. Doerr New Engl. J. Med. 348 2003 1967 1976
5. K. Anand, J. Ziebuhr, P. Wadhwani, J.R. Mesters, and R. Hilgenfeld Science 300 2003 1763
6. Tian, Q. Canadian Patent No CA 02376509, 2001
7. Tian, Q. Canadian Patent No CA 02376452, 2001
8. S. Peter, P.S. Dragovich, T.J. Prins, R. Zhou, T.O. Johnson, E.L. Brown, F.C. Maldonado, S.A. Fuhrman, L.S. Zalman, A.K. Patick, D.A. Matthews, X.J. Hou, J.W. Meador III, R.A. Ferre, and S.T. Worland Bioorg. Med. Chem. Lett. 12 2002 733
9. J. Jurczak, and A. Gołȩbiowski Chem. Rev. 89 1989 149 164
10. M. Cherest, H. Felkin, and N. Prudent Tetrahedron Lett. 1968 2199 2204
11. N.T. Anh Top. Curr. Chem. 88 1980 145 162
12. T.P. Loh, R.B. Wang, K.L. Tan, and K.Y. Sim Main Group Met. Chem. 20 1997 237 240
13. S. Steurer, and J. Podlech Eur. J. Org. Chem. 1999 1555 1560
14. +]: 374.1 (100%), 375.1 (41%)