Normal platelets possess the soluble form of IL-6 receptor

Cytokine

Volumn 29, Issue 1, 2005, Pages 13-17

  Marta, Rosana F ^a   Goette, Nora P ^a   Lev, Paola R ^a   Chazarreta, Carlos D ^a   Pirola, Carlos J ^a   Molinas, Felisa C ^a  

^a INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

Author keywords

Interleukin 6 soluble receptor; Interleukin 6; Platelets

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENALIN; GLYCOPROTEIN GP 130; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; THROMBIN;

ARTICLE; CELL TYPE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; THROMBOCYTE ACTIVATION; THROMBOCYTE FUNCTION; THROMBOCYTE MEMBRANE; WESTERN BLOTTING;

BLOOD PLATELETS; BLOTTING, WESTERN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; NEURAL CELL ADHESION MOLECULES; PLATELET ACTIVATION; PROTEIN BINDING; RECEPTORS, INTERLEUKIN-6; THROMBIN;

EID: 9644254255     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2004.09.003     Document Type: Article

References (21)

1. T. Kishimoto, S. Akira, M. Narazaki, and T. Taga Interleukin 6 family of cytokines and gp 130 Blood 86 1995 1243 1254
2. M. Peters, A. Abretch, and S. Rose-John Interleukin 6 and soluble interleukin 6 receptor: direct stimulation of gp 130 and hematopoiesis Blood 92 1998 3495 3504
3. A.W. Wognum, F.C.J.M. van Gils, and G. Wagemaker Flow cytometric detection of receptors for interleukin-6 on bone marrow and peripheral blood cells of human and rhesus monkeys Blood 81 1993 2036 2043
4. K. Nakayama Expression of IL-6, IL-6 receptor and its signal transducer pg130 mRNAs in megakaryocytic cell lines Leuk Lymphoma 29 1998 399 405
5. S. Navarro, N. Debili, J.P. Le Couedic, B. Klein, J. Breton-Gorius, J. Doly Interleukin-6 and its receptor are expressed by human megakaryocytes: in vitro effects on proliferation and endoreduplication Blood 77 1991 461 471
6. C. Wickenhauser, J. Lorenzen, J. Thiele, A. Hillienhof, K. Jungheim, B. Schmitz Secretion of cytokines (interleukin-1, -3, and -6 and granulocyte-macrophage colony-stimulating factor) by normal human bone marrow megakaryocytes Blood 85 1995 685 691
7. K. Yasukawa, T. Saito, T. Fukunaga, Y. Sekimori, Y. Koishihara, H. Fukui Purification and characterization of soluble human IL-6 receptor expressed in CHO cells J Biochem 108 1990 673 676
8. K. Nakashima, and T. Taga gp 130 and the IL-6 family of cytokines: signaling mechanism and thrombopoietic activities Sem Hematol 35 1998 210 221
9. J. Müllberg, H. Schooltink, T. Stoyan, M. Gunther, L. Graeve, G. Buse The soluble interleukin-6 receptor is generated by shedding Eur J Immunol 23 1993 473 480
10. J. Lust, K. Donovan, M. Kline, P. Griepp, R. Kyle, and N. Maihle Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor Cytokine 4 1992 96 100
11. L. Oleksowicz, Z. Mrowiec, D. Zuckerman, R. Isaacs, J. Dutcher, and E. Puszkin Platelet activation induced by Interleukin-6: evidence for a mechanism involving arachidonic acid metabolism Throm Haemost 72 1994 302 308
12. A. Oda, T. Nakahata, B. Druker, K. Ozaki, K. Tsuji, K. Yasukawa The combination of soluble IL-6 receptor and IL-6 induces tyrosine phosphorylation of GP130, Jak1, Jak2 and STAT3 in human platelets Blood 90 1997 (Abs 3018)
13. M. Peters, S. Jacobs, M. Ehlers, P. Vollmer, J. Müllberg, E. Wolf The function of the soluble IL-6 receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6 J Exp Med 183 1996 1399 1406
14. K. Althoff, P. Reddy, N. Voltz, S. Rose-John, and J. Mülberg Shedding of interleukin-6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins Eur J Biochem 267 2000 2624 2631
15. J. Mülberg, F. Duric, C. Ouen-Evans, M. Alderson, S. Rose-John, D. Cosman A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor J Immunol 155 1995 5198 5205
16. V. Matthews, B. Schuster, S. Schütze, I. Bussmeyer, A. Ludwig, and Ch. Hundhausen Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE) J Biol Chem 278 2003 38829 38839
17. N. Weich, A. Wang, M. Fitzgerald, T. Neben, D. Donaldson, J. Giannotti Recombinant human interleukin 11 directly promotes megakaryocytopoiesis in vitro Blood 90 1997 3893 3902
18. R. Kerr, D. Stirling, and Ch. Ludlam Interleukin 6 and haemostasis Br J Haematol 115 2001 3 12
19. M. Romano, M. Sironi, C. Toniatti, N. Polentarutti, P. Fruscella, P. Ghezzi Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment Immunity 6 1997 315 325
20. S. Levy-Toledano, R. Bredoux, F. Rendu, C. Jenneaux, E. Savarian, and E. Dassin Isolement et fonction de plaquettes. I. A partir du plasma rich en plaquettes, compareison de deux methods: filtration sur gel et centrifugation sur gradient d'albumine. II. Nouvelle methode a partir de sang total: centrifugation sur gradient de metrizamide Nouv Rev Fr Hematol 16 1976 367 374
21. G.V.R. Born Aggregation of blood platelets by adenosine diphosphate and its reversal Nature 194 1962 927 929