Modeling AIDS in a mouse

Hospital Practice

Volumn 31, Issue 9, 1996, Pages

  Mosier, Donald E ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ACTIVE IMMUNIZATION; ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; COMBINED IMMUNODEFICIENCY; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; REVIEW; T LYMPHOCYTE ACTIVATION; VIRUS INFECTIVITY;

EID: 9544253038     PISSN: 87502836     EISSN: None     Source Type: Journal    
DOI: 10.1080/21548331.1996.11443344     Document Type: Review

References (10)

1. Alkhatib G et al: CC CKR5: A RANTES, MIP-1a, MIP-1b receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272:1955, 1996
2. Levy JA: Pathogenesis of human immunodeficiency virus infection. Microbiol Rev 57:183, 1993
3. Liu R et al: Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86:367, 1996
4. McCune J et al: The SCID-hu mouse: A small animal model for HIV infection and pathogenesis. Annu Rev Immunol 9:399, 1991
5. Mosier DE et al: Human immunodeficiency virus Infection of human-PBL-SCID mice. Science 251:791, 1991
6. Mosier DE et al: Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp 160. Proc Natl Acad Sci USA 90:2443, 1993
7. Mosier DE et al: Rapid loss of CD4+ T cells in human-PBL-SCID mice by noncytopathic HIV isolates. Science 260:689, 1993
8. Mosier DE: Human immunodeficiency virus infection of human cells transplanted to severe combined immunodeficient mice. Adv Immunol (in press)
9. Parren PW et al: Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site. AIDS 9:F1, 1995
10. van Kuyk R et al: Cloned human CD8+ cytotoxic T lymphocytes protect human peripheral blood leukocyte-severe combined immunodeficient mice from HIV-1 infection by an HLA-unrestricted mechanism. J Immunol 153:4826, 1994