Protein kinase A activation is required for IL-1-induced nitric oxide production by cardiac myocytes

American Journal of Physiology - Cell Physiology

Volumn 271, Issue 1 40-1, 1996, Pages

  Oddis, Carmine V ^a   Simmons, Richard L ^a   Hattler, Brack G ^a   Finkel, Mitchell S ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

cytokines; heart; inducible nitric oxide synthase; interleukin 1; signal transduction

Indexed keywords

CALPHOSTIN C; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOKINE; INTERLEUKIN 1; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN KINASE C INHIBITOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HEART MUSCLE CELL; HEART VENTRICLE WALL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0029779964     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1996.271.1.c429     Document Type: Article

References (37)

1. Abbas, A. K., A. H. Lichtman, and J. S. Pober. Cellular and Molecular Immunology. Philadelphia, PA: Saunders, 1991, p. 225-243.
2. Balligand, J. L., D. Ungureanu-Longrois, W. W. Simmons, D. Pimentai, T. A. Malinski, M. Kapturczak, Z. Taha, C. J. Jowenstein, A. J. Davidoff, R. A. Kelly, T. W. Smith, and T. Michel. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. J. Biol. Chem. 269: 27580-27588, 1994.
3. Billiar, T. R., J. B. Madariagea, R. L. Simmons, and J. R. Lancaster, Jr. Induction of nitric oxide synthesis and its reactions in cultured human and rat hepatocytes stimulated with cytokines plus LPS. Biochem. Biophys. Res. Commun. 194: 826-835, 1993.
4. Brady, A. J. B., P. A. Poole-Wilson, S. E. Harding, and J. B. Warren. Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H1963-H1966, 1992.
5. Brady, A. J. B., J. B. Warren, P. A. Poole-Wilson, T. J. Williams, and S. E. Harding. Nitric oxide attenuates cardiac myocyte contraction. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H176-H182, 1993.
6. Bredt, D. S., P. M. Hwang, C. E. Glatt, C. Lowenstein, R. R. Reed, and S. H. Snyder. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature Lond. 351: 714-718, 1991.
7. Carrol, B. J. A study of the effects of catabolin on cyclic adenosine monophosphate biosynthesis and prostaglandin E2 secretion in pig articular chondrocytes. Br. J. Rheumatol. 25: 359-365, 1986.
8. Chomzynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
9. Dinerman, J. L., J. P. Steiner, T. M. Dawson, V. Dawson, and S. H. Snyder. Cyclic nucleotide dependent phosphorylation of neuronal nitric oxide synthase inhibits catalytic activity. Neuropharmacology 33: 1245-1251, 1994.
10. Finkel, M. S., R. A. Hoffman, L. Shen, C. V. Oddis, R. L. Simmons, and B. G. Battler. Interleukin-6 (IL-6) as a mediator of stunned myocardium. Am. J. Cardiol. 71: 1231-1232, 1993.
11. Finkel, M. S., C. V. Oddis, T. D. Jacob, S. L. Watkins, B. G. Hattler, and R. L. Simmons. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science Wash. DC 257: 387-389, 1992
12. Finkel, M. S., C. V. Oddis, O. H. Mayer, B. G. Hattler, and R. L. Simmons. Nitric oxide synthase inhibitor alters papillary muscles force-frequency relationship. J. Pharmacol. Exp. Ther. 272: 945-952, 1995.
13. Geller, D. A., C. J. Lowenstein, R. A. Shapiro, A. K. Nussler, M. DiSilvio, S. C. Wang, D. K. Nakayama, R. L. Simmons, S. H. Snyder, and T. R. Billiar. Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. Proc. Natl. Acad. Sci. USA 90: 3491-3495, 1993.
14. Han, R. O., P. E. Ray, K. L. Baughman, and A. M. Feldman. Detection of interleukin and interleukin-receptor mRNA in human heart by polymerase chain reaction. Biochem. Biophys. Res. Commun. 181: 520-523, 1991.
15. Ignarro, L. J. Signal transduction mechanisms involving nitric oxide. Biochem. Pharmacol. 41: 485-490, 1991.
16. Janssens, S. P., A. Shimouchi, T. Quertermous, D. B. Bloch, and K. D. Bloch. Cloning and expression of cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase. J. Biol. Chem. 267: 14519-14522, 1992.
17. Kemp, B. E., H. C. Cheng, and D. A. Walsh. Peptide inhibitors of cAMP-dependent protein kinase. Methods Enzymol. 159: 173-183, 1988.
18. Koide, M., Y. Kawahara, I. Nakayama, T. Tsuda, and M. Yodoyama. Cyclic AMP-elevating agents induce an inducible type of nitric oxide synthase in cultured vascular smooth muscle cells. J. Biol. Chem. 268: 24959-24966, 1993.
19. Kramnik, I., E. Skamene, and D. Radzioch. Assessment of lymphokine profiles in activated lymphocytes by semi-quantitative PCR. J. Immunol. Methods 162: 143-153, 1993.
20. Kunz, D., H. Muhl, G. Walker, and J. Pfeilschifter. Two distinct signaling pathways trigger the expression of inducible nitric oxide synthase in rat renal mesangial cells. Proc. Natl. Acad. Sci. USA 91: 5387-5391, 1994.
21. Lyons, C., G. Orloff, and J. Cunningham. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267: 6370-6374, 1992.
22. 2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterase through guanylyl cyclase activation. J. Biol. Chem. 268: 26286-26295, 1993.
23. Moncada, S., and A. Higgs. The L-arginine-nitric oxide pathway. N. Engl. J. Med. 329: 2002-2012, 1993.
24. Oddis, C. V., and M. S. Finkel. Cytokine-stimulated nitric oxide production inhibits mitochondrial activity in cardiac myocytes. Biochem. Biophys. Res. Commun. 213: 1002-1009, 1995.
25. Oddis, C. V., R. L. Simmons, B. G. Hattler, and M. S. Finkel. cAMP enhances inducible nitric oxide synthase mRNA stability in cardiac myocytes. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H2044-H2050, 1995.
26. Oddis, C. V., R. L. Simmons, B. G. Hattler, and M. S. Finkel. Chronotropic effects of cytokines and the nitric oxide synthase inhibitor, L-NMMA, on cardiac myocytes. Biochem. Biophys. Res. Commun. 205: 992-997, 1994.
27. Parillo, J. E. Pathogenic mechanisms of septic shock. N. Engl. J. Med. 328: 1471-1477, 1993.
28. Pradelles, P., J. Grass., D. Chabardes, and N. Guiso. Enzyme assays of adenosine cyclic 3′,5′-monophosphate and guanosine 3′,5′-monophosphate using acetylcholinesterase. Anal. Chem. 61: 447-453, 1989.
29. Roskoski, R. Assays of protein kinase. Methods Enzymol. 99: 3-6, 1983.
30. Rotenberg, S. A., M. H. Huang, J. Zhu, L. Su, and H. Ridel. Deletion analysis of protein kinase C inactivation by calphostin C. Mol. Carcinog. 12: 42-49, 1995.
31. 2+ in intact cardiac myocytes. Circ. Res. 74: 970-978, 1994.
32. Shaw, G., and R. Kamen. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46: 659-667, 1986.
33. Vincent, R., and D. Nadeau. Adjustment of the osmolality of percoll for the isopycnic separation of cells and cell organelles. Anal. Biochem. 141: 322-328, 1984.
34. Wahler, G. M., and S. J. Dollinger. Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-dependent protein kinase. Am. J. Physiol. 268 (Cell Physiol. 37): C45-C54, 1995.
35. Xie, Q. W., B. J. Cho, J. Calaycay, R. A. Mumford, K. M. Swiderek, T. D. Lee, A. Ding, T. Troso, and C. Nathan. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science Wash. DC 256: 225-228, 1992.
36. Yamamoto, K. G., G. Gonzalez, W. Biggs III, and M. Montminy. Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature Lond. 334: 494-498, 1988.
37. Zhang, Y. H., J. X. Lin, Y. K. Yip, and J. Vilcek. Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin-1 in human fibroblasts: role in the induction of interleukin-6. Proc. Natl. Acad. Sci. USA 85: 6802-6805, 1988.