Transportans

Cell-Penetrating Peptides: Processes and Applications

Volumn , Issue , 2002, Pages 53-70

  Pooga, Margus ^a   Hällbrink, Mattias ^b   Langel, Ülo ^b  

^a UNIVERSITY OF TARTU   (Estonia)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 9244225361     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (38)

1. Derossi, D. et al., The third helix of the Antennapedia homeodomain translocates through biological membranes, J. Biol. Chem., 269, 10444, 1994.
2. Vivés, E., Brodin, P., and Lebleu, B., A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus, J. Biol. Chem., 272, 16010, 1997.
3. Elliott, G. and O’Hare, P., Intercellular trafficking and protein delivery by a herpesvirus structural protein, Cell, 88, 223, 1997.
4. Chaloin, L. et al., Conformations of primary amphipathic carrier peptides in membrane mimicking environments, Biochemistry, 36, 11179, 1997.
5. Pooga, M. et al., Cell penetration by transportan, FASEB J., 12, 67, 1998.
6. Oehlke, J. et al., Cellular uptake of an alpha-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior nonendocytically, Biochim. Biophys. Acta., 1414, 127, 1998.
7. +-ATPase and reverses its inhibition by ouabain, Regul. Pept., 62, 47, 1996.
8. Land, T. et al., Linear and cyclic N-terminal galanin fragments and analogs as ligands at the hypothalamic galanin receptor, Int. J. Pept. Protein. Res., 38, 267, 1991.
9. Langel, Ü., Land, T., and Bartfai, T., Design of chimeric peptide ligands to galanin receptors and substance P receptors, Int. J. Pept. Protein. Res., 39, 516, 1992.
10. Consolo, S. et al., Galparan induces in vivo acetylcholine release in the frontal cortex, Brain Res., 756, 174, 1997.
11. Östenson, C-G. et al., Galparan: a powerful insulin-releasing chimeric peptide acting at a novel site, Endocrinology, 138, 3308, 1997.
12. Pooga, M. et al., Novel galanin receptor ligands, J. Pept. Res., 51, 65, 1998.
13. Heuser, J.E. and Anderson, R.G., Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation, J. Cell. Biol., 108, 389, 1989.
14. Lindgren, M. et al., Translocation properties of novel cell penetrating transportan and penetratin analogues, Bioconjug. Chem., 11, 619, 2000.
15. Soomets, U. et al., From galanin and mastoparan to galparan and transportan, Curr. Top. Pept. Protein. Res., 2, 83, 1997.
16. Higashijima, T. et al., Conformational change of mastoparan from wasp venom on binding with phospholipid membrane, FEBS Lett., 152, 227, 1983.
17. Higashijima, T. et al., Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins), J. Biol. Chem., 263, 6491, 1988.
18. Mousli, M. et al., G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides, Trends Pharmacol. Sci., 11, 358, 1990.
19. Zorko, M. et al., Differential regulation of GTPase activity by mastoparan and galparan, Arch. Biochem. Biophys., 349, 321, 1998.
20. Pooga, M. et al., Galanin-based peptides, galparan and transportan, with receptordependent and independent activities, Ann. N.Y. Acad. Sci., 863, 450, 1998.
21. Hällbrink, M. et al., Effects of vasopressin-mastoparan chimeric peptides on insulin release and G-protein activity, Regul. Pept., 82, 45, 1999.
22. Krishnakumari, V. and Nagaraj, R., Antimicrobial and hemolytic activities of crabrolin, a 13-residue peptide from the venom of the European hornet, Vespa crabro, and its analogs, J. Pept. Res., 50, 88, 1997.
23. Soomets, U. et al., Deletion analogues of transportan, Biochim. Biophys. Acta, 1467, 165, 2000.
24. Meldal, M. and Breddam, K., Anthranilamide and nitrotyrosine as a donor-acceptor pair in internally quenched fluorescent substrates for endopeptidases: multicolumn peptide synthesis of enzyme substrates for subtilisin Carlsberg and pepsin, Anal. Biochem., 195, 141, 1991.
25. Nielsen, P.E. et al., Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide, Science, 254, 1497-1500, 1991.
26. Kumar, R. et al., The first analogues of LNA (locked nucleic acids): phosphorothioate-LNA and 2′-thio-LNA, Bioorg. Med. Chem. Lett., 8, 2219, 1998.
27. Summerton, J., Morpholino antisense oligomers: the case for an RNase H-independent structural type, Biochim. Biophys. Acta, 1489, 141, 1999.
28. Ray, A. and Nordén, B., Peptide nucleic acid (PNA): its medical and biotechnical applications and promise for the future, FASEB J., 14, 1041, 2000.
29. Pooga, M. et al., Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo, Nat. Biotechnol., 16, 857, 1998.
30. Sei, S. et al., Identification of a key target sequence to block human immunodeficiency virus type 1 replication within the gag-pol transframe domain, J. Virol., 74, 4621, 2000.
31. Schwarze, S.R., Hruska, K.A., and Dowdy, S.F., Protein transduction: unrestricted delivery into all cells? Trends Cell. Biol., 10, 290, 2000.
32. Tsien, R.Y., The green fluorescent protein, Annu. Rev. Biochem., 67, 509, 1988.
33. Schwarze, S.R. et al., In vivo protein transduction: delivery of a biologically active protein into the mouse, Science, 285, 1569, 1999.
34. Peeters, J.M. et al., Comparison of four bifunctional reagents for coupling peptides to proteins and the effect of the three moieties on the immunogenicity of the conjugates, J. Immunol. Methods, 120, 133, 1989.
35. Bernatowicz, M.S., Matsueda, R., and Matsueda, G.R., Preparation of Boc-[S-(3-nitro-2-pyridinesulfenyl)]-cysteine and its use for unsymmetrical disulfide bond formation, Int. J. Pept. Protein. Res., 28, 107, 1986.
36. Lindberg, M. et al., Secondary structure and position of the cell-penetrating peptide transportan in SDS micelles as determined by NMR, Biochemistry, 40, 3141, 2001.
37. Brasseur, R., Differentiation of lipid-associating helices by use of three-dimensional molecular hydrophobicity potential calculations, J. Biol. Chem., 266, 16120, 1991.
38. Pooga, M. et al., Cellular translocation of proteins by transportan, FASEB J., 15, 1400, 2001.