-
1
-
-
0036005890
-
Interleukin-12 in anti-tumor immunity and immunotherapy
-
Colombo M.P., Trinchieri G. Interleukin-12 in anti-tumor immunity and immunotherapy. Cytokine Growth Factor Rev. 13:2002;155-168.
-
(2002)
Cytokine Growth Factor Rev.
, vol.13
, pp. 155-168
-
-
Colombo, M.P.1
Trinchieri, G.2
-
2
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nature Rev. Immunol. 3:2003;133-146.
-
(2003)
Nature Rev. Immunol.
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
3
-
-
0030589377
-
Immunotherapy of experimental metastases by vaccination with interleukin gene-transduced adenocarcinoma cells sharing tumor-associated antigens. Comparison between IL-12 and IL-2 gene-transduced tumor cell vaccines
-
Rodolfo M., Zilocchi C., Melani C., Cappetti B., Arioli I., Parmiani G., Colombo M.P. Immunotherapy of experimental metastases by vaccination with interleukin gene-transduced adenocarcinoma cells sharing tumor-associated antigens. Comparison between IL-12 and IL-2 gene-transduced tumor cell vaccines. J. Immunol. 157:1996;5536-5542.
-
(1996)
J. Immunol.
, vol.157
, pp. 5536-5542
-
-
Rodolfo, M.1
Zilocchi, C.2
Melani, C.3
Cappetti, B.4
Arioli, I.5
Parmiani, G.6
Colombo, M.P.7
-
4
-
-
0036099019
-
Significant antitumor effects obtained by autologous tumor cell vaccine engineered to secrete interleukin-12 (IL-12) and IL-18 by means of the EBV/lipoplex
-
Asada H., Kishida T., Hirai H., Satoh E., Ohashi S., Takeuchi M., Kubo T., Kita M., Iwakura Y., Imanishi J., Mazda O. Significant antitumor effects obtained by autologous tumor cell vaccine engineered to secrete interleukin-12 (IL-12) and IL-18 by means of the EBV/lipoplex. Mol. Ther. 5:2002;609-616.
-
(2002)
Mol. Ther.
, vol.5
, pp. 609-616
-
-
Asada, H.1
Kishida, T.2
Hirai, H.3
Satoh, E.4
Ohashi, S.5
Takeuchi, M.6
Kubo, T.7
Kita, M.8
Iwakura, Y.9
Imanishi, J.10
Mazda, O.11
-
5
-
-
0026110881
-
MHC expression on human tumors - Its relevance for local tumor growth and metastasis
-
Garrido F., Ruiz-Cabello F. MHC expression on human tumors - its relevance for local tumor growth and metastasis. Semin. Cancer Biol. 2:1991;3-10.
-
(1991)
Semin. Cancer Biol.
, vol.2
, pp. 3-10
-
-
Garrido, F.1
Ruiz-Cabello, F.2
-
6
-
-
31644435949
-
Tumor immunity and immuno-gene therapy of malignancies
-
Mazda, O., (Ed.), Research Signpost, Trivandrum, in press
-
O. Mazda, W.T. Germeraad, Tumor immunity and immuno-gene therapy of malignancies, in Frontiers in immuno-gene therapy, in: Mazda, O., (Ed.), Research Signpost, Trivandrum, in press.
-
Frontiers in Immuno-gene Therapy
-
-
Mazda, O.1
Germeraad, W.T.2
-
7
-
-
0019436124
-
Metastatic behavior of a murine reticulum cell sarcoma exhibiting organ-specific growth
-
Hart I.R., Talmadge J.E., Fidler I.J. Metastatic behavior of a murine reticulum cell sarcoma exhibiting organ-specific growth. Cancer Res. 41:1981;1281-1287.
-
(1981)
Cancer Res.
, vol.41
, pp. 1281-1287
-
-
Hart, I.R.1
Talmadge, J.E.2
Fidler, I.J.3
-
8
-
-
0033026947
-
Augmentation of local antitumor immunity in the liver by tumor vaccine modified to secrete murine interleukin 12
-
Fuji N., Fujiwara H., Ueda Y., Taniguchi F., Yoshimura T., Oka T., Yamagishi H. Augmentation of local antitumor immunity in the liver by tumor vaccine modified to secrete murine interleukin 12. Gene Ther. 6:1999;1120-1127.
-
(1999)
Gene Ther.
, vol.6
, pp. 1120-1127
-
-
Fuji, N.1
Fujiwara, H.2
Ueda, Y.3
Taniguchi, F.4
Yoshimura, T.5
Oka, T.6
Yamagishi, H.7
-
9
-
-
17944369209
-
In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice
-
Kishida T., Asada H., Satoh E., Tanaka S., Shinya M., Hirai H., Iwai M., Tahara H., Imanishi J., Mazda O. In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice. Gene Ther. 8:2001;1234-1240.
-
(2001)
Gene Ther.
, vol.8
, pp. 1234-1240
-
-
Kishida, T.1
Asada, H.2
Satoh, E.3
Tanaka, S.4
Shinya, M.5
Hirai, H.6
Iwai, M.7
Tahara, H.8
Imanishi, J.9
Mazda, O.10
-
10
-
-
10744223089
-
Electrochemo-gene therapy of cancer: Intratumoral delivery of interleukin-12 gene and bleomycin synergistically induced therapeutic immunity and suppressed subcutaneous and metastatic melanomas in mice
-
Kishida T., Asada H., Itokawa Y., Yasutomi K., Shin-Ya M., Gojo S., Cui F.D., Ueda Y., Yamagishi H., Imanishi J., Mazda O. Electrochemo-gene therapy of cancer: intratumoral delivery of interleukin-12 gene and bleomycin synergistically induced therapeutic immunity and suppressed subcutaneous and metastatic melanomas in mice. Mol. Ther. 8:2003;738-745.
-
(2003)
Mol. Ther.
, vol.8
, pp. 738-745
-
-
Kishida, T.1
Asada, H.2
Itokawa, Y.3
Yasutomi, K.4
Shin-Ya, M.5
Gojo, S.6
Cui, F.D.7
Ueda, Y.8
Yamagishi, H.9
Imanishi, J.10
Mazda, O.11
-
11
-
-
0033019078
-
Potent antitumor effects mediated by local expression of the mature form of the interferon-gamma inducing factor, interleukin-18 (IL-18)
-
Osaki T., Hashimoto W., Gambotto A., Okamura H., Robbins P.D., Kurimoto M., Lotze M.T., Tahara H. Potent antitumor effects mediated by local expression of the mature form of the interferon-gamma inducing factor, interleukin-18 (IL-18). Gene Ther. 6:1999;808-815.
-
(1999)
Gene Ther.
, vol.6
, pp. 808-815
-
-
Osaki, T.1
Hashimoto, W.2
Gambotto, A.3
Okamura, H.4
Robbins, P.D.5
Kurimoto, M.6
Lotze, M.T.7
Tahara, H.8
-
12
-
-
0021988550
-
Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells
-
Yates J.L., Warren N., Sugden B. Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells. Nature. 313:1985;812-815.
-
(1985)
Nature
, vol.313
, pp. 812-815
-
-
Yates, J.L.1
Warren, N.2
Sugden, B.3
-
13
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
Liu F., Song Y., Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther. 6:1999;1258-1266.
-
(1999)
Gene Ther.
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
14
-
-
0033166561
-
High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
-
Zhang G., Budker V., Wolff J.A. High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. Hum. Gene Ther. 10:1999;1735-1737.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1735-1737
-
-
Zhang, G.1
Budker, V.2
Wolff, J.A.3
-
15
-
-
0034777596
-
Highly efficient gene transfer into murine liver achieved by intravenous administration of naked Epstein-Barr virus (EBV)-based plasmid vectors
-
Cui F.D., Kishida T., Ohashi S., Asada H., Yasutomi K., Satoh E., Kubo T., Fushiki S., Imanishi J., Mazda O. Highly efficient gene transfer into murine liver achieved by intravenous administration of naked Epstein-Barr virus (EBV)-based plasmid vectors. Gene Ther. 8:2001;1508-1513.
-
(2001)
Gene Ther.
, vol.8
, pp. 1508-1513
-
-
Cui, F.D.1
Kishida, T.2
Ohashi, S.3
Asada, H.4
Yasutomi, K.5
Satoh, E.6
Kubo, T.7
Fushiki, S.8
Imanishi, J.9
Mazda, O.10
-
16
-
-
0036728587
-
Improvement of nonviral gene therapy by Epstein-Barr virus (EBV)-based plasmid vectors
-
Mazda O. Improvement of nonviral gene therapy by Epstein-Barr virus (EBV)-based plasmid vectors. Curr. Gene Ther. 2:2002;379-392.
-
(2002)
Curr. Gene Ther.
, vol.2
, pp. 379-392
-
-
Mazda, O.1
-
17
-
-
0037384220
-
IL-12: A promising adjuvant for cancer vaccination
-
Portielje J.E., Gratama J.W., van Ojik H.H., Stoter G., Kruit W.H. IL-12: a promising adjuvant for cancer vaccination. Cancer Immunol. Immunother. 52:2003;133-144.
-
(2003)
Cancer Immunol. Immunother.
, vol.52
, pp. 133-144
-
-
Portielje, J.E.1
Gratama, J.W.2
Van Ojik, H.H.3
Stoter, G.4
Kruit, W.H.5
-
18
-
-
0031895957
-
Vaccination with IL-12 gene-modified autologous melanoma cells: Preclinical results and a first clinical phase I study
-
Sun Y., Jurgovsky K., Moller P., Alijagic S., Dorbic T., Georgieva J., Wittig B., Schadendorf D. Vaccination with IL-12 gene-modified autologous melanoma cells: preclinical results and a first clinical phase I study. Gene Ther. 5:1998;481-490.
-
(1998)
Gene Ther.
, vol.5
, pp. 481-490
-
-
Sun, Y.1
Jurgovsky, K.2
Moller, P.3
Alijagic, S.4
Dorbic, T.5
Georgieva, J.6
Wittig, B.7
Schadendorf, D.8
-
19
-
-
0028897739
-
Inhibition of angiogenesis in vivo by interleukin 12
-
Voest E.E., Kenyon B.M., O'Reilly M.S., Truitt G., D'Amato R.J., Folkman J. Inhibition of angiogenesis in vivo by interleukin 12. J. Natl. Cancer Inst. 87:1995;581-586.
-
(1995)
J. Natl. Cancer Inst.
, vol.87
, pp. 581-586
-
-
Voest, E.E.1
Kenyon, B.M.2
O'Reilly, M.S.3
Truitt, G.4
D'Amato, R.J.5
Folkman, J.6
-
20
-
-
0034652459
-
Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12
-
Duda D.G., Sunamura M., Lozonschi L., Kodama T., Egawa S., Matsumoto G., Shimamura H., Shibuya K., Takeda K., Matsuno S. Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12. Cancer Res. 60:2000;1111-1116.
-
(2000)
Cancer Res.
, vol.60
, pp. 1111-1116
-
-
Duda, D.G.1
Sunamura, M.2
Lozonschi, L.3
Kodama, T.4
Egawa, S.5
Matsumoto, G.6
Shimamura, H.7
Shibuya, K.8
Takeda, K.9
Matsuno, S.10
-
21
-
-
0032583475
-
Gene transfer in vitro and in vivo with Epstein-Barr virus-based episomal vector results in markedly high transient expression in rodent cells
-
Tomiyasu K., Satoh E., Oda Y., Nishizaki K., Kondo M., Imanishi J., Mazda O. Gene transfer in vitro and in vivo with Epstein-Barr virus-based episomal vector results in markedly high transient expression in rodent cells. Biochem. Biophys. Res. Commun. 253:1998;733-738.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.253
, pp. 733-738
-
-
Tomiyasu, K.1
Satoh, E.2
Oda, Y.3
Nishizaki, K.4
Kondo, M.5
Imanishi, J.6
Mazda, O.7
-
22
-
-
0036173196
-
Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor
-
Lui V.W., He Y., Falo L., Huang L. Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor. Hum. Gene Ther. 13:2002;177-185.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 177-185
-
-
Lui, V.W.1
He, Y.2
Falo, L.3
Huang, L.4
-
23
-
-
0034779612
-
Combined IL-12 and GM-CSF gene therapy for murine hepatocellular carcinoma
-
Wang Z., Qiu S.J., Ye S.L., Tang Z.Y., Xiao X. Combined IL-12 and GM-CSF gene therapy for murine hepatocellular carcinoma. Cancer Gene. Ther. 8:2001;751-758.
-
(2001)
Cancer Gene. Ther.
, vol.8
, pp. 751-758
-
-
Wang, Z.1
Qiu, S.J.2
Ye, S.L.3
Tang, Z.Y.4
Xiao, X.5
-
24
-
-
0034152996
-
Hypothesis: Naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process
-
Budker V., Budker T., Zhang G., Subbotin V., Loomis A., Wolff J.A. Hypothesis: naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process. J. Gene Med. 2:2000;76-88.
-
(2000)
J. Gene Med.
, vol.2
, pp. 76-88
-
-
Budker, V.1
Budker, T.2
Zhang, G.3
Subbotin, V.4
Loomis, A.5
Wolff, J.A.6
-
25
-
-
0035007717
-
Hepatic uptake and gene expression mechanisms following intravenous administration of plasmid DNA by conventional and hydrodynamics-based procedures
-
Kobayashi N., Kuramoto T., Yamaoka K., Hashida M., Takakura Y. Hepatic uptake and gene expression mechanisms following intravenous administration of plasmid DNA by conventional and hydrodynamics-based procedures. J. Pharmacol. Exp. Ther. 297:2001;853-860.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.297
, pp. 853-860
-
-
Kobayashi, N.1
Kuramoto, T.2
Yamaoka, K.3
Hashida, M.4
Takakura, Y.5
-
26
-
-
0033893570
-
Long-term expression of human alpha1-antitrypsin gene in mouse liver achieved by intravenous administration of plasmid DNA using a hydrodynamics-based procedure
-
Zhang G., Song Y.K., Liu D. Long-term expression of human alpha1-antitrypsin gene in mouse liver achieved by intravenous administration of plasmid DNA using a hydrodynamics-based procedure. Gene Ther. 7:2000;1344-1349.
-
(2000)
Gene Ther.
, vol.7
, pp. 1344-1349
-
-
Zhang, G.1
Song, Y.K.2
Liu, D.3
-
27
-
-
0035080761
-
Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth
-
Yang J., Chen S., Huang L., Michalopoulos G.K., Liu Y. Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth. Hepatology. 33:2001;848-859.
-
(2001)
Hepatology
, vol.33
, pp. 848-859
-
-
Yang, J.1
Chen, S.2
Huang, L.3
Michalopoulos, G.K.4
Liu, Y.5
-
28
-
-
0036446111
-
Development of catheter-based procedures for transducing the isolated rabbit liver with plasmid DNA
-
Eastman S.J., Baskin K.M., Hodges B.L., Chu Q., Gates A., Dreusicke R., Anderson S., Scheule R.K. Development of catheter-based procedures for transducing the isolated rabbit liver with plasmid DNA. Hum. Gene Ther. 13:2002;2065-2077.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 2065-2077
-
-
Eastman, S.J.1
Baskin, K.M.2
Hodges, B.L.3
Chu, Q.4
Gates, A.5
Dreusicke, R.6
Anderson, S.7
Scheule, R.K.8
-
29
-
-
0141430606
-
Hepatocyte growth factor gene therapy of liver cirrhosis by naked plasmid DNA transfer into liver
-
Fujimoto J., Kanemura H., Takeuchi M., Horiguchi K., Ueki T., Sawa Y., Morishita R., Nakamura T., Kaneda Y. Hepatocyte growth factor gene therapy of liver cirrhosis by naked plasmid DNA transfer into liver. Mol. Ther. 1:2000;s22-s22.
-
(2000)
Mol. Ther.
, vol.1
-
-
Fujimoto, J.1
Kanemura, H.2
Takeuchi, M.3
Horiguchi, K.4
Ueki, T.5
Sawa, Y.6
Morishita, R.7
Nakamura, T.8
Kaneda, Y.9
-
30
-
-
0035111572
-
Efficient expression of naked DNA delivered intraarterially to limb muscles of nonhuman primates
-
Zhang G., Budker V., Williams P., Subbotin V., Wolff J.A. Efficient expression of naked DNA delivered intraarterially to limb muscles of nonhuman primates. Hum. Gene Ther. 12:2001;427-438.
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 427-438
-
-
Zhang, G.1
Budker, V.2
Williams, P.3
Subbotin, V.4
Wolff, J.A.5
|