Corticosteroid treatment in meconium aspiration syndrome: A solution for better outcome?

Acta Paediatrica, International Journal of Paediatrics

Volumn 93, Issue 1, 2004, Pages 5-7

  Kaapa P ^a  

^a UNIVERSITY OF TURKU   (Finland)

Author keywords

Corticosteroids; Inflammation; Meconium aspiration syndrome

Indexed keywords

CORTICOSTEROID; INTERLEUKIN 8; PHOSPHOLIPASE A2;

ACUTE DISEASE; ANTIINFLAMMATORY ACTIVITY; DISEASE SEVERITY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; HUMAN; LUNG FUNCTION; LUNG HEMODYNAMICS; LUNG LAVAGE; LUNG PARENCHYMA; MECONIUM ASPIRATION; MEDICAL RESEARCH; OXYGENATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVIEW;

ADRENAL CORTEX HORMONES; ANIMALS; HUMANS; INFANT; INFANT, NEWBORN; MECONIUM ASPIRATION SYNDROME; SWINE;

EID: 9144254443     PISSN: 08035253     EISSN: None     Source Type: Journal    
DOI: 10.1080/08035250310007646     Document Type: Review

References (22)

1. Cleary GM, Wiswell TE. Meconium-stained amniotic fluid and the meconium aspiration syndrome. Pediatr Clin North Am 1998; 45: 511-29
2. Davey AM, Becker JD, Davis JM. Meconium aspiration syndrome: physiological and inflammatory changes in a newborn piglet model. Pediatr Pulmonol 1993; 16: 101-8
3. Tyler DC, Murphy J, Cheney FW. Mechanical and chemical damage to lung tissue caused by meconium aspiration. Pediatrics 1978; 62: 454-9
4. Wiswell TE. Advances in the treatment of the meconium aspiration syndrome. Acta Pædiatr 2001; Suppl 436: 28-30
5. Salvia-Roigés MD, Carbonell-Estrany X, Figueras-Aloy J, Rodríguez-Miguélez JM. Efficacy of three treatment schedules in severe meconium aspiration syndrome. Acta Pædiatr 2004; 93: 60-65
6. Kinsella JP. Meconium aspiration syndrome. Is surfactant lavage the answer? Am J Respir Crit Care Med 2003; 168: 413-4
7. 4-surfactant in models of meconium aspiration syndrome. Pediatr Res 1998; 44: 705-15
8. Holopainen R, Laine J, Halkola L, Aho H, Kääpä P. Dexamethasone treatment attenuates pulmonary injury in piglet meconium aspiration. Pediatr Res 2001; 49: 1-7
9. Soukka HR, Halkola LT, Aho HJ, Rautanen MJ, Kero PO, Kääpä PO. Methylprednisolone attenuates the pulmonary hypertensive response in porcine meconium aspiration. Pediatr Res 1997; 42: 1-6
10. Khan AM, Shabarek FM, Kutchback JW, Lally KP. Effects of dexamethasone on meconium aspiration syndrome in newborn piglets. Pediatr Res 1999; 46: 179-83
11. 2 activity and induces cellular injury and apoptosis in piglet lungs. Pediatr Res 1999; 46: 626-32
12. de Beufort AJ, Pelikan DMV, Elferink JGR, Berger HM. Effect of interleukin 8 in meconium on in-vitro neutrophil chemotaxis. Lancet 1998; 352: 102-5
13. Zagariya A, Bhat R, Uhal B, Navale S, Freidine M, Vidyasagar D. Cell death and lung cell histology in meconium aspirated newborn rabbit lung. Eur J Pediatr 2000; 159: 819-26
14. Jones CA, Cayabyab RG, Kwong KYC, Stotts C, Wong B, Hamdan H, et al. Undetectable interleukin (IL)-10 and persistent IL-8 expression early in hyaline membrane disease: a possible developmental basis for the predisposition to chronic lung inflammation in preterm newborns. Pediatr Res 1996; 39: 966-75
15. Wang JY, Yeh TF, Lin YJ, Chen WY, Lin CH. Early postnatal dexamethasone therapy may lessen lung inflammation in premature infants with respiratory distress syndrome on mechanical ventilation. Pediatr Pulmonol 1997; 23: 193-7
16. da Costa DE, Nair AK, Pai MG, Al Khusaiby SM. Steroids in full term infants with respiratory failure and pulmonary hypertension due to meconium aspiration syndrome. Eur J Pediatr 2001; 160: 150-3
17. Franz ID, Wang NS, Thach BT. Experimental meconium aspiration: effects of glucocorticoid treatment. J Pediatr 1975; 86: 438-41
18. Yeh TF, Srinivasan G, Harris V, Pildes RS. Hydrocortisone therapy in meconium aspiration syndrome: a controlled study. J Pediatr 1977; 90: 140-3
19. Wu JM, Yeh TF, Wang JY, Wang JN, Lin YJ, Hsieh WS, et al. The role of pulmonary inflammation in the development of pulmonary hypertension in newborns with meconium aspiration syndrome (MAS). Pediatr Pulmonol 1999; Suppl 18: 205-8
20. Holopainen R, Soukka H, Kääpä P. Meconium aspiration induces a concentration-dependent pulmonary hypertension in newborn piglets. Pediatr Pulmonol 1998; 25: 107-13
21. Korhonen K, Soukka H, Halkola L, Peuravuori H, Aho H, Pulkki K, et al. Meconium induces only localized inflammatory lung injury in piglets. Pediatr Res 2003; 54: 1-6
22. Morris HG. Mechanisms of glucocorticoid action in pulmonary disease. Chest 1985; 88: 133S-41S