Dexamethasone treatment attenuates pulmonary injury in piglet meconium aspiration

Pediatric Research

Volumn 49, Issue 2, 2001, Pages 162-168

  Holopainen, R ^a   Laine, J ^a   Halkola, L ^a   Aho, H ^a   Kaapa P ^a  

^a UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; LUNG ALVEOLUS EPITHELIUM; LUNG ARTERY PRESSURE; LUNG HEMODYNAMICS; LUNG INJURY; LUNG VASCULAR RESISTANCE; MECONIUM ASPIRATION; NEWBORN; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; SWINE;

EID: 0035141185     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-200102000-00006     Document Type: Article

References (32)

1. Meconium staining and the meconium aspiration syndrome
2. Mechanical and chemical damage to lung tissue caused by meconium aspiration
3. Meconium aspiration syndrome: Physiological and inflammatory changes in a newborn piglet model
4. Mechanisms of glucocorticoid action in pulmonary disease
5. Early postnatal dexamethasone therapy may lessen lung inflammation in premature infants with respiratory distress syndrome on mechanical ventilation
6. Two doses of early intravenous dexamethasone for the prevention of bronchopulmonary dysplasia in babies with respiratory distress syndrome
7. Prophylactic effects of dexamethasone in lung injury caused by hyperoxia and hyperventilation
8. Experimental meconium aspiration: Effects of glucocorticoid treatment
9. Hydrocortisone therapy in meconium aspiration syndrome: A controlled study
10. Methylprednisolone attenuates the pulmonary hypertensive response in porcine meconium aspiration
11. Adaptation of the pulmonary circulation to extrauterine life in the pig and its relevance to the human infant
12. Meconium aspiration induces a concentration dependent pulmonary hypertensive response in newborn piglets
13. Lipopolysaccharide induced apoptosis of rat pancreatic acinar cells
14. 2 catalytic activity concentration in human serum and ascites
15. 2 activity and induces cellular injury and apoptosis in piglet lungs
16. Methylprednisolone prevention of increased lung vascular permeability following endotoxemia in sheep
17. Prophylactic and delayed treatment with high-dose methylprednisolone in a porcine model of early ARDS induced by endotoxaemia
18. The effects of methylprednisolone on lung injury in mice
19. The pulmonary vasculature in meconium aspiration
20. Effects of high-dose corticosteroids on the pulmonary circulation
21. Dexamethasone and indomethacin modify endotoxin-induced respiratory failure in pigs
22. Meconiuminduced lung injury mediated by activation of alveolar macrophages
23. Undetectable interleukin (IL)-10 and persistent IL-8 expression early in hyaline membrane disease: A possible developmental basis for the predisposition to chronic lung inflammation in preterm newborns
24. 2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells
25. 2 activity and gene expression are simulated by tumor necrosis factor: Dexamethasone blocks the induced synthesis
26. ++ accumulation in type II pneumocytes
27. 2
28. 2-induced pathophysiologic changes in the guinea pig lung
29. Apoptosis in disease
30. Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation
31. Glucocorticoid and progesterone inhibit involution and programmed cell death in the mouse mammary gland
32. Dexamethasone inhibits lung epithelial cell apoptosis induced by IFN-γ and Fas