Butyrate increases apoptosis induced by different antineoplastic drugs in monocytic leukemia cells

Chemotherapy

Volumn 50, Issue 5, 2004, Pages 221-228

  Ramos, M G ^a   Rabelo, F L A ^a   Brumatti, G ^b   Bueno da Silva, A E ^b   Amarante Mendes, G P ^b   Alvarez Leitea, J I ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antineoplastic drugs; Apoptosis; Butyrate; Leukemia

Indexed keywords

BUTYRIC ACID; CASPASE 3; CASPASE 8; CASPASE 9; DEXAMETHASONE; FLUOROURACIL; VINCRISTINE;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA DETERMINATION; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL;

AMINO ACID CHLOROMETHYL KETONES; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BUTYRATES; CASPASES; CELL LINE, TUMOR; CYTARABINE; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; ETOPOSIDE; HUMANS; LEUKEMIA, MONOCYTIC, ACUTE; VINCRISTINE;

EID: 9144249299     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000081942     Document Type: Article

References (27)

1. Webb SJ, Harrison DJ, Wyllie AH: Apoptosis: An overview of the process and its relevance in disease. Adv Pharmacol 1997;41:1-34.
2. Gibson S, Widmann C, Johnson G: Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents. J Biol Chem 1999;274:10916-10922.
3. Ramos MG, Rabelo FLA, Duarte T, Gazzinelli RT, Alvarez-Leite J: Butyrate induces apoptosis in murine macrophages via caspase-3, but independent of autocrine synthesis of tumor necrosis factor and nitric oxide. Braz J Med Biol Res 2002;35:161-173.
4. Kurita-Ochiai T, Fukushima K, Ochiai K: Butyric acid-induced apoptosis of murine thymocytes, splenic T cells and human Jurkat cells. Infect Immun 1997;65:35-41.
5. McBain JA, Eastman A, Nobel CS, Mueller GC: Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors. Biochem Pharmacol 1997;53:1357-1368.
6. Kruh J, Defer N, Tichonicky L: Effects of butyrate on cell proliferation and gene expression; in Cummings JH, Rombeau JL, Sakata T (eds): Physiological and Clinical Aspects of Short Chain Fatty Acids. Cambridge, Cambridge University Press, 1995.
7. Santini V, Gozzini A, Scappini B: Induction of apoptosis by monosaccharide butyrate derivatives in chronic lymphocytic leukemia cells. Haematologica 1999;84:897-904.
8. Solary E, Bertrand R, Pommier Y: Apoptosis of human leukemic HL-60 cells induced to differentiate by phorbol ester treatment. Leukemia 1994;8:792-797.
9. Ramos MG, Bambirra EA, Nicoli JR, Cara DC, Vieira EC: Protection by short-chain fatty acids against 1-beta-D-arabinofuranosylcytosine-induced intestinal lesions in germfree mice. Antimicrob Agents Chemother 1999;43:950-953.
10. Bernhard D, Loffler M, Hartmann BH, Yoshida M, Kofler R, Csordas A: Interaction between dexamethasone and butyrate in apoptosis induction: Non-additive in thymocytes and synergistic in a T cell-derived leukemia cell line. Cell Death Differ 1999;6:609-617.
11. Rahmani M, Dai Y, Grant S: The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-α mediated process. Exp Cell Res 2002;277:31-47.
12. Bras-Gonçalves RA, Pocard M, Formento J, Poirson-Bichat F, Pinieux G, Pandrea I, Arvelo F, Poupon MF: Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis. Gastroenterology 2001;120:874-886.
13. Conway RM, Madigan MC, Billson FA, Penfold PL: Vincristine and cisplatin induced apoptosis in human retinoblastoma, potentiation by sodium butyrate. Eur J Cancer 1998;34:1741-1748.
14. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991;139:271-279.
15. Amarante-Mendes GP, Naekyung Kim C, Liu L, Huang Y, Perkins CL, Green DR, Bhalla K: Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3. Blood 1998;91:1700-1705.
16. Lauricella M, Calvaruso G, Giuliano M, Carabillo M, Emanuele S, Vento R, Tesoriere G: Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells. Tumor Biol 2000;21:337-348.
17. Giermasz A, Makowski M, Kozlowska E, Nowis D, Maj M, Jalili A, Feleszko W, Wojcik C, Dabrowska A, Jakobisiak M, Golab J: Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice. Int J Cancer 2002;97:746-750.
18. Ruemmele FM, Schwartz S, Seidman EG, Dionne S, Levy E, Lentze MJ: Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway. Gut 2003;52:94-100.
19. Los M, Burek CJ, Stroh C, Benedyk K, Hug H, Mackiewicz A: Anticancer drugs of tomorrow: Apoptotic pathways as targets for drug design. Drug Discov Today 2003;8:67-77.
20. Kurita-Ochiai T, Ochiai K, Fukushima K: Butyric acid-induced T-cell apoptosis is mediated by caspase-8 and -9 activation in a Fas-independent manner. Clin Diagn Lab Immunol 2001;8:325-332.
21. Robertson JD, Enoksson M, Suomela M, Zhivotovsky B, Orrenius S: Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis. J Biol Chem 2002;277:29803-29809.
22. Lu C, Fu W, Zhao D, Mattson MP: The DNA damaging agent etoposide activates a cell survival pathway involving alpha-amino-3-hydroxy-5- methylisoxazole-4-propionate receptors and mitogen-activated protein kinases in hippocampal neurons. J Neurosci Res 2002;70:671-679.
23. Endo K, Oki E, Biedermann V, Kojima H, Yoshida K, Johannes FJ, Kufe D, Datta R: Proteolytic cleavage and activation of protein kinase C [micro] by caspase-3 in the apoptotic response of cells to 1-beta-D- arabinofuranosylcytosine and other genotoxic agents. J Biol Chem 2000;275:18476-18481.
24. Stadheim TA, Saluta GR, Kucera GL: Role of c-Jun N-terminal kinase/p38 stress signaling in 1-beta-D-arabinofuranosylcytosine-induced apoptosis. Biochem Pharmacol 2000;59:407-418.
25. Srivastava RK, Srivastava AR, Korsmeyer SJ, Nesterova M, Cho-Chung YS, Longo DL: Involvement of microtubules in the regulation of bcl-2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase. Mol Cell Biol 1998;18:3509-3517.
26. Giuliano M, Lauricella M, Calvaruso G, Carabillo M, Emanuele S, Vento R, Tesoriere G: The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells. Cancer Res 1999;59:5586-5595.
27. Rabelo FL, Ropert C, Ramos MG, Bonjardim CA, Gazzinelli RT, Alvarez-Leite J: Inhibition of ERK1/2 and CREB phosphorylation by caspase-dependent mechanism enhances apoptosis in a fibrosarcoma cell line treated with butyrate. Biochem Biophys Res Commun 2003; 303:968-972.