Protection by short-chain fatty acids against 1-β-D- arabinofuranosylcytosine-induced intestinal lesions in germfree mice

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 4, 1999, Pages 950-953

  Ramos, Mariana Gontijo ^a   Bambirra, Eduardo Alves ^a   Nicoli, Jacques Robert ^b   Cara, Denise Carmona ^b   Vieira, Enio Cardillo ^a   Alvarez Leite, Jacqueline ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; PLACEBO; SHORT CHAIN FATTY ACID;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GERMFREE ANIMAL; HISTOPATHOLOGY; INTESTINE INJURY; INTRAGASTRIC DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MORPHOMETRICS; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTECTION;

EID: 0344628689     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.4.950     Document Type: Article

References (14)

1. 13C-NMR spectroscopy. Biochemistry 23:6398-6402.
2. Frankel, W. L., W. Zhang, A. Singh, D. M. Klurfeld, S. Don, T. Sakata, and J. L. Rombeau. 1994. Mediation of the trophic effects of short chain fatty acids on the rat jejunum and colon. Gastroenterology 106:385-390.
3. Harada, E., and S. Kato. 1983. Effect of short chain fatty acids on the secretory response of the ovine exocrine pancreas. Am. J. Physiol. 244:G284-G290.
4. 2 breath test. Scand. J. Gastroenterol. 17:373-378.
5. Kim, Y. 1998. Short chain fatty acid in ulcerative colitis. Nutr. Rev. 56:17-24.
6. Kvietys, P. R., and D. N. Granger. 1981. Effects of volatile fatty acids on blood flow and oxygen uptake by dog colon. Am. J. Physiol. 80:962-969.
7. Linseisen, J., and G. Wolfran. 1997. Efficacy of different triglycerides in total parenteral nutrition for preventing atrophy of the gut in traumatized rats. J. Parenter. Enteral Nutr. 21:21-26.
8. Lupton, L. R. 1995. Short chain fatty acids and colon tumorigenesis, p. 307-318. In J. H. Cummings, J. L. Rombeau, and T. Sakata (ed.). Physiological and clinical aspects of short chain fatty acids. Cambridge University Press, New York, N.Y.
9. Medina, V., J. J. Afonso, H. Alvarez-Arguelles, C. Hernandez, and F. Gonzalez. 1998. Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer. J. Parenter. Enteral Nutr. 22:14-17.
10. Pleasents, J. R. 1974. Gnotobiotics, p. 119-174. In E. C. Melby, Jr., and N. H. Altman (ed.), CRC handbook of laboratory animal science, vol. 1. CRC Press, Cleveland, Ohio.
11. Ramos, M. G., E. A. Bambirra, D. C. Cara, E. C. Vieira, and J. I. Alvarez-Leite. 1997. Oral administration of short chain fatty acids reduces the intestinal mucositis caused by treatment with Ara-c in mice fed commercial or elemental diets. Nutr. Cancer 26:211-219.
12. Remesy, C., and C. Demigné. 1976. Partition and absorption of volatile fatty acids in the alimentary canal of the rat. Ann. Rech. Vet. 7:39-55.
13. Wagner, M. 1959. Determination of germfree status. Ann. N. Y. Acad. Sci. 78:89-101.
14. Young, G. P., and P. R. Gibson. 1995. Butyrate and human cancer cell, p. 319-336. In J. H. Cummings, J. L. Rombeau, and T. Sakata (ed.). Physiological and clinical aspects of short chain fatty acids. Cambridge University Press. New York, N.Y.