Two-dimensional chemotherapy simulations demonstrate fundamental transport and tumor response limitations involving nanoparticles

Biomedical Microdevices

Volumn 6, Issue 4, 2004, Pages 297-309

  Sinek, J ^a   Frieboes, H ^b   Zheng, X ^a   Cristini, V ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California at Irvine   (United States)

Author keywords

Anti angiogenic therapy; Convection; Diffusion; Drug; In silico chemotherapy; Nanoparticles; Transport; Tumor simulation; Virtual cancer

Indexed keywords

COMPUTER SIMULATION; DIFFUSION; DRUG PRODUCTS; MATHEMATICAL MODELS; NANOSTRUCTURED MATERIALS; TOXICITY; TUMORS; TWO DIMENSIONAL;

ANGIOGENESIS; BLOODSTREAMS; DIFFUSIVE TRANSPORT; TUMOR CELLS;

CHEMOTHERAPY;

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; NANOPARTICLE;

ANGIOGENESIS; ARTICLE; CELL DEATH; CELL TYPE; CHEMOTAXIS; COMPUTER MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG RESPONSE; DRUG SENSITIVITY; DRUG TRANSPORT; GLIOBLASTOMA; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; TISSUE GROWTH; TOXICITY; TUMOR CELL; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT, ACTIVE; COMPUTER SIMULATION; DIAGNOSIS, COMPUTER-ASSISTED; DRUG CARRIERS; DRUG THERAPY, COMPUTER-ASSISTED; HUMANS; MODELS, BIOLOGICAL; NANOTUBES; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; TREATMENT OUTCOME;

EID: 9144249023     PISSN: 13872176     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:BMMD.0000048562.29657.64     Document Type: Article

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