'Serological Biopsy' in First-Degree Relatives of Patients with Gastric Cancer Affected by Helicobacter pylori Infection

Scandinavian Journal of Gastroenterology

Volumn 38, Issue 12, 2003, Pages 1223-1227

  Di Mario, F ^a   Moussa, A M ^b   Caruana, P ^b   Merli, R ^b   Cavallaro, L G ^b   Cavestro, G M ^b   Dal Bo N ^b   Iori, V ^b   Pilotto, A ^b   Leandro, G ^b   Franze A ^b   Rugge, M ^b  

^a UNIVERSITY OF PARMA   (Italy)

^b NONE

Author keywords

Family relatives; Gastric cancer; H. pylori; Serum pepsinogens

Indexed keywords

ANTIBODY; BACTERIUM ANTIBODY; CAGA PROTEIN; GASTRIN 17; IMMUNOGLOBULIN G; PEPSINOGEN I; PEPSINOGEN II;

ADULT; AGED; ALCOHOL CONSUMPTION; ANALYTIC METHOD; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CANCER PATIENT; CLINICAL ARTICLE; COFFEE; CONTROLLED STUDY; DYSPEPSIA; FAMILY HISTORY; FEMALE; GASTROINTESTINAL SYMPTOM; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MALE; MORPHOLOGY; PATIENT REFERRAL; PRIORITY JOURNAL; RELATIVE; SEROLOGICAL BIOPSY; SEROLOGY; SMOKING HABIT; STATISTICAL SIGNIFICANCE; STOMACH BIOPSY; STOMACH CANCER; STOMACH FUNCTION; TITRIMETRY;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BIOLOGICAL MARKERS; DYSPEPSIA; FAMILY HEALTH; FEMALE; GASTRINS; GASTRITIS, ATROPHIC; GENETIC PREDISPOSITION TO DISEASE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; PEPSINOGEN A; PEPSINOGEN C; STOMACH NEOPLASMS;

EID: 9144239262     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365520310007044     Document Type: Article

References (34)

1. International Agency for Research on Cancer Schistosomes, liver flukes and Helicobacter pylori IARC monographs on the evaluation of carcinogenic risks to humans vol. 61 Lyon, France: IARC; 1994.
2. Ekstròm AM, Held M, Hansson L-E, Engstrand L, Nyrèn O. Helicobacter pylori in gastric cancer established by CagA immunoblot as a marker of past infection. Gastroenterology 2001;121:784-91.
3. Huang J-Q, Sridhar S, Chen Y, Hunt RH. Meta-analysis of the relationship between H. pylori seropositivity and gastric cancer. Gastroenterology 1998;114:1169-79.
4. Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, et al. Helicobacter pylori infection and the development of gastrica cancer. N Engl J Med. 2001;345:829-32.
5. Correa P. Chronic gastritis as a cancer precursor. Scand J Gastroenterol 1984;Suppl 104:131-6.
6. Correa P. Human gastric carcinogenesis: a multistep and multi-factorial process. First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res 1992;52: 6735-40.
7. Azuma T, Ito S, Sato F, Yamazaki Y, Miyaji H, Ito Y, et al. The role of the HLA-DQA1 gene in resistance to atrophic gastritis and gastric adenocarcinoma induced by Helicobacter pylori infection. Cancer 1998;182:1013-8.
8. Blaser MJ, Perez Perez GI, Kleanthous H, Cover IL, Peek RM, Chyou PH, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995;55:2111-5.
9. Parsonnet J, Friedman GD, Orentrich N, Vogelman H. Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection. Gut 1997;40:297-301.
10. Sipponen P, Kekki M, Haapakoski J, Ihamàki T, Siurala M. Gastric cancer risk in chronic atrophic gastritis: statistical calculations of cross-sectional data. Int J Cancer 1985;35:173-7.
11. El-Omar EM, Carrington M, Chow WH, McColl KEL, Bream JH, Young HA, et al. Nature 2000;404:398-402.
12. Wolfe MM, Nompleggi DJ. Cytokine inhibition of gastric acid secretion. A little goes a long way. Gastroenterology 1992;102: 2177-8.
13. Brenner H, Bode G, Boeing H. Helicobacter pylori infection among offspring of patients with stomach cancer. Gastroenterology 2000;118:31-5.
14. Chang YW, Han YS, Lee DK, Kim HJ, Lim HS, Moon JS, et al. Role of Helicobacter pylori infection among offspring or siblings of gastric cancer patients. Int J Cancer 2002;101:469-74.
15. El-Omar EM, Karin O, Murray LS, El-Nujumi A, Wirrz A, Gillen D, et al. Increased prevalence of precancerous changes in relatives of gastric cancer patients: critical role of H. pylori. Gastroenterology 2000;118:22-30.
16. Malfertheiner P, Megraud F, O'Morain C, Hungin APS, Jones R, Axon A, et al, and the European H. Pylori Study Group: Current concepts in the management of H. pylori infection - The Maastricht2: 2000 Consensus Report. Aliment Pharmacol Ther 2002;16:167-80.
17. Oksanen A, Sipponen P, Miettinen A, Sarna S, Rautelin H. Evaluation of blood tests to predict normal gastric mucosa. Scand J Gastroenterol 2000;35:791-5.
18. Korstanje A, den Hartog G, Biemond I, Lamers CB. The serological gastric biopsy: a non-endoscopical diagnostic approach in management of the dyspeptic patient: significance for primary care based on a survey of the literature. Scand J Gastroenterol 2002;Suppl 236:22-6.
19. Samloff IM, Varis K, Ihamaki T, Siurala M, Rotter IJ. Relationships among serum pepsinogen I, serum pepsinogen II, and gastric mucosal histology. A study in relatives of patients with pernicious anemia. Gastroenterology 1982;83:204-9.
20. Plebani M, Basso D, Cassaro M, Brigato L, Scrigner M, Toma A, et al. Helicobacter serology in patients with chronic gastritis. Am J Gastroenterol 1996;91:954-8.
21. Màrdh E, Màrdh S, Màrdh B, Borch K. Diagnosis of gastritis by means of a combination of serological analyses. Clin Chim Acta 2002;320:17-27.
22. Kekki M, Samloff IM, Varis K, Ihamàki T. Serum pepsinogens and serum gastrin in screening of severe atrophic gastritis. Scand J Gastroenterol 1991;186:109-16.
23. Varis K, Sipponen P, Laxén F, Samloff IM, Huttunen JK, Taylor PR, et al. Implications of serum pepsinogen I in early endoscopie diagnosis of gastric cancer. Scand J Gastroenterol 2000;35: 950-6.
24. Yoshihara M, Sumii K, Haruma K, Kiyohira K, Hattori N, Kitadai Y, et al. Correlation of ratio of serum pepsinogen I and II with prevalence of gastric cancer and adenoma in Japanese subjects. Am J Gastroenterol 1998;93:1090-6.
25. Farinati F, Di Mario F, Plebani M, Cielo R, Fanton MC, Valiante F, et al. Pepsinogen A/pepsinogen C or pepsinogen A multiplied by gastrin in the diagnosis of gastric cancer. Ital J Gastroenterol 1991;23:194-6.
26. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The Updated Sydney System. Am J Surg Pathol 1996;20:1161-81.
27. Knight T, Wyatt J, Wilson A, Graeves S, Newell D, Hengels K, et al. Helicobacter pylori gastritis and serum pepsinogen levels in a healthy population: development of a biomarkers strategy for gastric atrophy in high risk groups. Br J Cancer 1996;73:819-24.
28. Bodger K, Wyatt Judy I, Heatley Richard V. Variation in serum pepsinogens with severity and topography of Helicobacter pylori-associated chronic gastritis in dyspeptic patients referred for endoscopy. Helicobacter 2001;16:216-24.
29. Samloff IM, Varis K, Ihamàki T, Siurala M, Rotter JI. Serum pepsinogens I and II and gastric acid output: effect of gastritis. In: Clinical and genetic advances. Alan R. Liss, Inc; 1985. p. 129-38.
30. Plebani M, Basso D, Scrigner M, Toma A, Di Mario F, Dal Bò N, et al. Serum pepsinogen C: a useful marker of H. pylori eradication? J Clin Lab Anal 1996;10:1-5.
31. Plebani M, Di Mario F, Stanghellini V, Delle Fave G. 'Serological tests to monitor treatment of Helicobacter pylori'. Lancet 1992;340:51-2.
32. Vaira D, Gatta L, Ricci C, Miglioli M. Review article: Diagnosis of Helicobacter pylori infection. Aliment Pharmacol Ther 2002; 16 Suppl 1:16-23.
33. Annibale B, Negrini R, Caruana P, Lahner E, Grossi C, Bordi C, Delle Fave G. Two-thirds of atrophic body gastritis patients have evidence of helicobacter infection. Helicobacter 6:225-33.
34. Karnes WE, Jr, Samloff IM, Siurala M, Kekki M, Sipponen P, Kim SWR, et al. Positive antibody and negative tissue staining for H. pylori in subjects with atrophic body gastritis. Gastroenterology 1991;101:167-74.