Inhibition of HIV-1 envelope glycoprotein-mediated cell fusion by a DL-amino acid-containing fusion peptide: Possible recognition of the fusion complex

Journal of Biological Chemistry

Volumn 279, Issue 46, 2004, Pages 48224-48230

  Gerber, Doron ^a   Pritsker, Moshe ^a   Gunther Ausborn, Susanne ^b,c   Johnson, Benitra ^b   Blumenthal, Robert ^b   Shai, Yechiel ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b NATIONAL CANCER INSTITUTE   (United States)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; CELLS; CHOLESTEROL; ENERGY TRANSFER; FLUORESCENCE; FOURIER TRANSFORM INFRARED SPECTROSCOPY; IMMUNOLOGY; PROTEINS;

FLUORESCENCE ENERGY TRANSFER; FUSION PEPTIDE (FP); HUMAN IMMUNODEFICIENCY VIRUS (HIV);

VIRUSES;

AMINO TERMINAL FUSION PEPTIDE; CHOLESTEROL; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; HYBRID PROTEIN; ISOLEUCINE; PHENYLALANINE; PHOSPHATIDYLCHOLINE; SPHINGOMYELIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL FUSION; CELL MEMBRANE; CELL VACUOLE; CELLULAR DISTRIBUTION; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INFRARED SPECTROSCOPY; MEMBRANE FUSION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; T LYMPHOCYTE; WILD TYPE;

AMINO ACIDS; CELL FUSION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIV FUSION INHIBITORS; HIV-1; HUMANS; MEMBRANE MICRODOMAINS; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; T-LYMPHOCYTES; VIRAL ENVELOPE PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 9144236332     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403436200     Document Type: Article

References (63)

1. White, J. M. (1992) Science 258, 917-924
2. Veronese, F. D., DeVico, A. L., Copeland, T. D., Oroszlan, S., Gallo, R. C., and Sarngadharan, M. G. (1985) Science 229, 1402-1405
3. Salzwedel, K., and Berger, E. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 12794-12799
4. Lasky, L. A., Nakamura, G., Smith, D. H., Fennie, C., Shimasaki, C., Patzer, E., Berman, P., Gregory, T., and Capon, D. J. (1987) Cell 50, 975-985
5. Dragic, T., Litwin, V., Allaway, G. P., Martin, S. R., Huang, Y., Nagashima, K. A., Cayanan, C., Maddon, P. J., Koup, R. A., Moore, J. P., and Paxton, W. A. (1996) Nature 381, 667-673
6. Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., Wu, L., Mackay, C. R., LaRosa, G., Newman, W., Gerard, N., Gerard, C., and Sodroski, J. (1996) Cell 85, 1135-1148
7. Rucker, J., Edinger, A. L., Sharron, M., Samson, M., Lee, B., Berson, J. F., Yi, Y., Margulies, B., Collman, R. G., Doranz, B. J., Parmentier, M., and Doms, R. W. (1997) J. Virol. 71, 8999-9007
8. Kowalski, M., Potz, J., Basiripour, L., Dorfman, T., Goh, W. C., Terwilliger, E., Dayton, A., Rosen, C., Haseltine, W., and Sodroski, J. (1987) Science 237, 1351-1355
9. Gallaher, W. R. (1987) Cell 50, 327-328
10. Bosch, M. L., Earl, P. L., Fargnoli, K., Picciafuoco, S., Giombini, F., Wong-Staal, F., and Franchini, G. (1989) Science 244, 694-697
11. Freed, E. O., Myers, D. J., and Risser, R. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 4650-4654
12. Delahunty, M. D., Rhee, I., Freed, E. O., and Bonifacino, J. S. (1996) Virology 218, 94-102
13. Blumenthal, R., Clague, M. J., Durell, S. R., and Epand, R. M. (2003) Chem. Rev. 103, 53-69
14. Lear, J. D., and DeGrado, W. F. (1987) J. Biol. Chem. 262, 6500-6505
15. Rafalski, M., Lear, J. D., and DeGrado, W. F. (1990) Biochemistry 29, 7917-7922
16. Slepushkin, V. A., Melikyan, G. B., Sidorova, M. S., Chumakov, V. M., Andreev, S. M., Manulyan, R. A., and Karamov, E. V. (1990) Biochem. Biophys. Res. Commun. 172, 952-957
17. Burger, K. N., Wharton, S. A., Demel, R. A., and Verkleij, A. J. (1991) Biochemistry 30, 11173-11180
18. Clague, M. J., Knutson, J. R., Blumenthal, R., and Herrmann, A. (1991) Biochemistry 30, 5491-5497
19. Epand, R. M., and Epand, R. F. (1994) Biochem. Biophys. Res. Commun. 202, 1420-1425
20. Rapaport, D., and Shai, Y. (1994) J. Biol. Chem. 269, 15124-15131
21. Gray, C., Tatulian, S. A., Wharton, W. A., and Tamm, L. K. (1996) Biophys. J. 70, 2275-2286
22. Martin, I., Schaal, H., Scheid, A., and Ruysschaert, J. M. (1996) J. Virol. 70, 298-304
23. Kliger, Y., Aharoni, A., Rapaport, D., Jones, P., Blumenthal, R., and Shai, Y. (1997) J. Biol. Chem. 272, 13496-13505
24. Ruiz-Arguello, M. B., Goni, F. M., Pereira, F. B., and Nieva, J. L. (1998) J. Virol. 72, 1775-1781
25. Pritsker, M., Jones, P., Blumenthal, R., and Shai, Y. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7287-7292
26. Chernomordik, L., Kozlov, M. M., and Zimmerberg, J. (1995) J. Membr. Biol. 146, 1-14
27. Pereira, F. B., Goni, F. M., Muga, A., and Nieva, J. L. (1997) Biophys. J. 73, 1977-1986
28. Pritsker, M., Rucker, J., Hoffman, T. L., Doms, R. W., and Shai, Y. (1999) Biochemistry 38, 11359-11371
29. Sackett, K., and Shai, Y. (2002) Biochemistry 41, 4678-4685
30. Merrifield, R. B., Vizioli, L. D., and Boman, H. G. (1982) Biochemistry 21, 5020-5031
31. Kelsey, D. R., Flanagan, T. D., Young, J., and Yeagle, P. L. (1990) J. Biol. Chem. 265, 12178-12183
32. Owens, R. J., Tanner, C. C., Mulligan, M. J., Srinivas, R. V., and Compans, R. W. (1990) AIDS Res. Hum. Retroviruses 6, 1289-1296
33. Gerber, D., and Shai, Y. (2002) J. Mol. Biol. 322, 491-495
34. Jonak, Z. L., Clark, R. K., Matour, D., Trulli, S., Craig, R., Henri, E., Lee, E. V., Greig, R., and Debouck, C. (1993) AIDS Res. Hum. Retroviruses 9, 23-32
35. Rapaport, D., and Shai, Y. (1992) J. Biol. Chem. 267, 6502-6509
36. Rapaport, D., Hague, G. R., Pouny, Y., and Shai, Y. (1993) Biochemistry 32, 3291-3297
37. Nussbaum, O., Broder, C. C., and Berger, E. A. (1994) J. Virol. 68, 5411-5422
38. Morris, S. J., Sarkar, D. P., White, J. M., and Blumenthal, R. (1989) J. Biol. Chem. 264, 3972-3978
39. van Eden, W., Thole, J. E., van der Zee, R., Noordzij, A., van Embden, J. D., Hensen, E. J., and Cohen, I. R. (1988) Nature 331, 171-173
40. Moscho, A., Orwar, O., Chiu, D. T., Modi, B. P., and Zare, R. N. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11443-11447
41. Hetru, C., Letellier, L., Oren, Z., Hoffmann, J. A., and Shai, Y. (2000) Biochem. J. 345, 653-664
42. Fung, B. K., and Stryer, L. (1978) Biochemistry 17, 5241-5248
43. Gazit, E., and Shai, Y. (1993) Biochemistry 32, 12363-12371
44. Sackett, K., and Shai, Y. (2003) J. Mol. Biol. 333, 47-58
45. de Almeida, R. F., Fedorov, A., and Prieto, M. (2003) Biophys. J. 85, 2406-2416
46. Jackson, M., and Mantsch, H. H. (1995) CRC Crit. Rev. Biochem. Mol. Biol. 30, 95-120
47. Tamm, L. K., and Tatulian, S. A. (1997) Q. Rev. Biophys. 30, 365-429
48. Yang, J., and Weliky, D. P. (2003) Biochemistry 42, 11879-11890
49. Gordon, L. M., Mobley, P. W., Pilpa, R., Sherman, M. A., and Waring, A. J. (2002) Biochim. Biophys. Acta 1559, 96-120
50. Avrahami, D., Oren, Z., and Shai, Y. (2001) Biochemistry 40, 12591-12603
51. Lalezari, J. P., Henry, K., O'Hearn, M., Montaner, J. S., Piliero, P. J., Trottier, B., Walmsley, S., Cohen, C., Kuritzkes, D. R., Eron, J. J., Jr., Chung, J., DeMasi, R., Donatacci, L., Drobnes, C., Delehanty, J., and Salgo, M. (2003) N. Engl. J. Med. 348, 2175-2185
52. Sharon, M., Oren, Z., Shai, Y., and Anglister, J. (1999) Biochemistry 38, 15305-15316
53. Karle, I. L., Gopi, H. N., and Balaram, P. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 13946-13951
54. Oren, Z., Ramesh, J., Avrahami, D., Suryaprakash, N., Shai, Y., and Jelinek, R. (2002) Eur. J. Biochem. 269, 3869-3880
55. Burny, A., Bex, F., Brasseur, R., Khim, M. C., Delchambre, M., Horth, M., and Verdin, E. (1988) J. Acquired Immune DefiC. Syndr. 1, 579-582
56. Martin, I., Defrise-Quertain, F., Decroly, E., Vandenbranden, M., Brasseur, R., and Ruysschaert, J. M. (1993) Biochim. Biophys. Acta 1145, 124-133
57. Brasseur, R., Cornet, B., Burny, A., Vandenbranden, M., and Ruysschaert, J. M. (1988) AIDS Res. Hum. Retroviruses 4, 83-90
58. Durell, S. R., Martin, I., Ruysschaert, J. M., Shai, Y., and Blumenthal, R. (1997) Mol. Membr. Biol. 14, 97-112
59. Gallo, S. A., Finnegan, C. M., Viard, M., Raviv, Y., Dimitrov, A., Rawat, S. S., Puri, A., Durell, S., and Blumenthal, R. (2003) Biochim. Biophys. Acta 1614, 36-50
60. Han, X., Bushweller, J. H., Cafiso, D. S., and Tamm, L. K. (2001) Nat. Struct. Biol. 8, 715-720
61. Cladera, J., Martin, I., and O'Shea, P. (2001) EMBO J. 20, 19-26
62. Takeda, M., Leser, G. P., Russell, C. J., and Lamb, R. A. (2003) Proc. Natl. Acad. Sci. U. S. A.
63. Jiang, S., Lin, K., Strick, N., and Neurath, A. R. (1993) Biochem. Biophys. Res. Commun. 195, 533-538