Photocontrol of Smad2, a multiphosphorylated cell-signaling protein, through caging of activating phosphoserines

Angewandte Chemie - International Edition

Volumn 43, Issue 43, 2004, Pages 5800-5803

  Hahn, Michael E ^a   Muir, Tom W ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Bioorganic chemistry; Phosphorylation; Photochemistry; Proteins; Semisynthesis

Indexed keywords

ACTIVATION ANALYSIS; BIOCHEMISTRY; CELLS; IRRADIATION; PHOSPHORS; REACTION KINETICS; ULTRAVIOLET RADIATION;

KINETIC ANALYSIS; PHOSPHOSERINE RESIDUES; PHOTOCONTROL;

PROTEINS;

PHOSPHATE; PHOSPHOPROTEIN; PHOSPHOSERINE; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL LABELING; KINETICS; MACROMOLECULE; MOLECULAR SIZE; PEPTIDE SYNTHESIS; PHOTOLYSIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; REGULATORY MECHANISM; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SIGNAL TRANSDUCTION; TECHNIQUE; ULTRAVIOLET IRRADIATION;

BINDING SITES; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR MIMICRY; PHOSPHORYLATION; PHOSPHOSERINE; PHOTOCHEMISTRY; SIGNAL TRANSDUCTION; X-RAY DIFFRACTION;

EID: 8844266024     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200461141     Document Type: Article

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