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Volumn 6, Issue 22, 2004, Pages 3977-3980

Efficient synthesis of acylsilanes using morpholine amides

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; MORPHOLINE DERIVATIVE; SILANE DERIVATIVE;

EID: 8744303700     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0483854     Document Type: Article
Times cited : (37)

References (53)
  • 5
    • 0035835953 scopus 로고    scopus 로고
    • (e) Moser, W. H. Tetrahedron 2001, 57, 2065-2084.
    • (2001) Tetrahedron , vol.57 , pp. 2065-2084
    • Moser, W.H.1
  • 46
    • 8744225720 scopus 로고    scopus 로고
    • note
    • (b) Sigma-Aldrich pricing: N,O-dimethylhydroxylamine•HCl costs $195/mol, while morpholine is only $13/mol (calculation based on 100 g bottles).
  • 47
    • 37049108024 scopus 로고
    • Dimethylphenylsilyllithium is easily prepared from the incubation of commercially available dimethylphenylsilyl chloride and finely cut lithium metal in THF at 0°C for 40 h. The resulting dark red suspension is used after titration according to: Fleming, I.; Newton, T. W.; Roessler, F. J. Chem. Soc., Perkin Trans. 1 1981, 2527-2532.
    • (1981) J. Chem. Soc., Perkin Trans. 1 , pp. 2527-2532
    • Fleming, I.1    Newton, T.W.2    Roessler, F.3
  • 48
    • 8744256820 scopus 로고    scopus 로고
    • note
    • Table 2, entry 3, has been performed on a 55 mmol scale to yield acylsilane 3c. See Supporting Information for details.
  • 51
    • 8744296177 scopus 로고    scopus 로고
    • note
    • Employing additional 2-substituted aromatic heterocycles (e.g., N-methyl pyrroyl, thiophen-2-yl) was not successful using the current reaction conditions.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.