Constraints of the 9-methyl group binding pocket of the rhodopsin chromophore probed by 9-halogeno substitution

Biochemistry

Volumn 43, Issue 46, 2004, Pages 14802-14810

  Wang, Yajie ^a   Bovee Geurts, Petra H M ^b   Lugtenburg, Johan ^a   DeGrip, Willem J ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; FOURIER TRANSFORM INFRARED SPECTROSCOPY; MATHEMATICAL MODELS; PHOTOCHEMICAL REACTIONS; PHOTOSENSITIVITY;

CUMULATIVE STRAIN; PHOTOPIGMENTS; PHOTOPRODUCTS;

CHROMOPHORES;

BROMINE; CHLORINE; FLUORINE; HALOGEN; HYDROGEN; IODINE; METHYL GROUP; PIGMENT; RETINAL; RETINAL DERIVATIVE; RHODOPSIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CHROMATOPHORE; COMPARATIVE STUDY; INFRARED SPECTROSCOPY; PHOTOCHEMISTRY; PRIORITY JOURNAL; SUBSTITUTION REACTION;

ANIMALS; BINDING SITES; CATTLE; FREEZING; HALOGENS; ISOMERISM; LIGANDS; OPSIN; PROTEIN BINDING; RETINALDEHYDE; RHODOPSIN; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 8744236234     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048404h     Document Type: Article

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