Over expression of thioredoxin-1 in transgenic mice attenuates germ cell apoptosis induced by experimental cryptorchidism

Journal of Urology

Volumn 172, Issue 6 I, 2004, Pages 2479-2482

  Okubo, Kazutoshi ^a   Nakamura, Hajime ^a,b   Watanabe, Jun ^a   Kamoto, Toshiyuki ^a   Yodoi, Junji ^a   Ogawa, Osamu ^a   Nishiyama, Hiroyuki ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Apoptosis; Cryptorchidism; Infertility, male; Testis; Thioredoxin

Indexed keywords

THIOREDOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CRYPTORCHISM; GENE OVEREXPRESSION; GERM CELL; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SCROTUM; SPECIES COMPARISON; TESTIS WEIGHT; TRANSGENIC MOUSE;

EID: 8644227826     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000138474.13112.67     Document Type: Article

References (20)

1. Jensen, T. K., Toppari, J., Keiding, N. and Skakkebaek, N. E.: Do environmental estrogens contribute to the decline in male reproductive health? Clin Chem, 41: 1896, 1995
2. Kumagai, A., Kodama, H., Kumagai, J., Fukuda, J., Kawamura, K., Tanikawa, H. et al: Xanthine oxidase inhibitors suppress testicular germ cell apoptosis induced by experimental cryptorchidism. Mol Hum Reprod, 8: 118, 2002
3. Yin, Y., Dewolf, W. C. and Morgentaler, A.: Experimental cryptorchidism induces testicular germ cell apoptosis by p53-dependent and independent pathways in mice. Biol Reprod, 58: 492, 1998
4. Ogi, S., Tanji, N., Yokoyama, M., Takeuchi, M. and Terada, N.: Involvement of Fas in the apoptosis of mouse germ cells induced by experimental cryptorchidism. Urol Res, 28: 17, 1998
5. Peltola, V., Huhtaniemi, I. and Ahotupa, M.: Abdominal position of the rat testis is associated with high level of lipid peroxidation. Biol Reprod, 53: 1146, 1995
6. Nakamura, H., Nakamura, K. and Yodoi, J.: Redox regulation of cellular activation. Annu Rev Immunol, 15: 351, 1997
7. Takagi, Y., Mitsui, A., Nishiyama, A., Nozaki, K., Sono, H., Gon, Y. et al: Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage. Proc Natl Acad Sci USA, 96: 4131, 1999
8. Shioji, K., Kishimoto, C., Nakamura, H., Masutani, H., Yuan, Z., Oka, S. et al: Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity. Circulation, 108: 1403, 2002
9. Okuyama, H., Nakamura, H., Shimahara, Y., Araya, S., Kawada, N., Yamaoka, Y. et al: Overexpression of thioredoxin prevents acute hepatitis caused by thioacetamide or lipopolysaccharide in mice. Hepatology, 37: 1015, 2003
10. Miranda-Vizuete, A., Ljung, J., Damdimopoulos, A. E., Gustafsson, J. A., Oko, R., Pelto-Huikko, M. et al: Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa. J Biol Chem, 276: 31567, 2001
11. Miranda-Vizuete, A., Tsang, K., Yu, Y., Jimenez, A., Pelto-Huikko, M., Flickinger, C.J. et al: Cloning and developmental analysis of murid spermatid-specific thioredoxin-2 (SPTRX-2), a novel sperm fibrous sheath protein and autoantigen. J Biol Chem, 278: 44874, 2003
12. Matsui, M., Oshima, M., Oshima, H., Takaku, K., Maruyama, T., Yodoi, J. et al: Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. Dev Biol, 178: 179, 1996
13. Tanaka, T., Hosoi, F., Yamaguchi-Iwai, Y., Nakamura, H., Masutani, H., Ueda, S. et al: Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis. EMBO J, 21: 1695, 2002
14. Nonn, L., Williams, R. R., Erickson, R. P. and Powis, G.: The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice. Mol Cell Biol, 23: 916, 2003
15. Mitsui, A., Hamuro, J., Nakamura, H., Kondo, N., Hirabayashi, Y., Ishizaki-Koizumi, S. et al.: Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span. Antioxid Redox Signal, 4: 693, 2002
16. Hirota, K., Nakamura, H., Arai, T., Ishii, H., Bai, J., Itoh, T. et al: Geranylgeranylacetone enhances expression of thioredoxin and suppresses ethanol-induced cytotoxicity in cultured hepatocytes. Biochem Biophys Res Commun, 275: 825, 2000
17. Pentikainen, V., Suomalainen, L., Erkkila, K., Martelin, E., Parvinen, M., Pentikainen, M. O. et al: Nuclear factor-kappa B activation in human testicular apoptosis. Am J Pathol, 160: 205, 2002
18. Sigman, M. and Jarow, J. P.: Male infertility. In: Campbell's Urology, 8th ed. Edited by P. C. Walsh, A. B. Retik, E. D. Vaughan, Jr. and A. J. Wein. Philadelphia: W. B. Saunders Co., vol. 2, sect. VII, chapt. 43, pp. 1475-1531, 2002
19. Nakamura, H., Matsuda, M., Furuke, K., Kitaoka, Y., Iwata, S., Toda, K. et al: Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol Lett, 42: 75, 1994
20. Hoshino, T., Nakamura, H., Okamoto, M., Kato, S., Araya, S., Nomiyama, K. et al: Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury. Am J Respir Crit Care Med, 168: 1075, 2003