Xanthine oxidase inhibitors suppress testicular germ cell apoptosis induced by experimental cryptorchidism

Molecular Human Reproduction

Volumn 8, Issue 2, 2002, Pages 118-123

  Kumagai, Akiko ^a   Kodama, Hideya ^b   Kumagai, Jin ^a   Fukuda, Jun ^a   Kawamura, Kazuhiro ^a   Tanikawa, Hideo ^a   Sato, Naoki ^a   Tanaka, Toshinobu ^a  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b AKITA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Cryptorchidism; Male infertility; Testis; Xanthine oxidase

Indexed keywords

8 [3 METHOXY 4 (PHENYLSULFINYL)PHENYL]PYRAZOLO[1,5 A][1,3,5]TRIAZIN 4 OL; ALLOPURINOL; ANTIOXIDANT; DNA FRAGMENT; REACTIVE OXYGEN METABOLITE; XANTHINE OXIDASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEGENERATION; CELL PROTECTION; CONTROLLED STUDY; CRYPTORCHISM; DISEASE ASSOCIATION; DNA CLEAVAGE; HEAT STRESS; MALE INFERTILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SCROTUM; SPERMATOCYTE; TESTIS WEIGHT;

ANIMALIA;

EID: 0036172311     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/8.2.118     Document Type: Article

References (32)

1. Prevention of testicular damage by free-radical scavengers
2. Impaired detoxification of reactive oxygen and consequent oxidative stress in experimentally cryptorchid rat testis
3. Maturation of redox regulatory mechanisms in the epididymis
4. The effect of allopurinol pretreatment before detorting testicular torsion
5. Oxygen-dependent microbial killing by phagocytes
6. Milk xanthine oxidase type D (dehydrogenase) and type O (oxidase). Purification, interconvention and some properties
7. Effects of scrotal heating on testicular enzymes and spermatogenesis in the rat
8. Oxidative stress as mediator of apoptosis
9. Early changes in the germinal epithelium of rat testes following exposure to heat
10. The germinal epithelium of cryptorchid testes experimentally induced in prepuberal and adult rats
11. Ischemia-reperfusion injury: Role of oxygen-derived free radicals
12. Apoptotic cell death in the normal and cryptorchid human testis: The effect of human chorionic gonadotropin on testicular cell survival
13. In-situ quantification of stage-specific apoptosis in the rat seminiferous epithelium: Effects of short-term experimental cryptorchidism
14. Role of radical oxygen species in rat testicular germ cell apoptosis induced by heat stress
15. Changes in xanthine oxidase in ischemic rat brain
16. Role of oxidative stress in single-dose, cadmium-induced testicular cancer
17. Development of the rectum-testis temperature difference in the post-natal rat
18. Oxygen-derived free radicals in postischemic tissue injury
19. Mechanisms of conversion of xanthine dehydrogenase to xanthine oxidase in ischemic rat liver and kidney
20. Properties of gonads as controllers of somatic and physical characteristics: Testicular reactions in experimental cryptorchidism
21. Allopurinol and oxypurinol are hydroxyl radical scavengers
22. Viability of meiotic prophase spermatocytes of rats is facilitated in primary culture of dispersed testicular cells on collagen gel by meiotic prophase spermatocytes complete meiotic divisions in vitro
23. Mammalian spermatogenesis: Effects of experimental cryptorchidism in the rat and non-descent of the testis in man
24. Mechanism of inhibition of xanthine oxidase with a new tight binding inhibitor
25. Abdominal position of the rat testis is associated with high level of lipid peroxidation
26. Rescue of testicular function after acute experimental torsion
27. Experimentally induced cryptorchidism increases apoptosis in rat testis
28. Prevention of free radical-induced myocardial reperfusion injury with allopurinol
29. The significance of testicular reactive oxygen species on testicular histology in infertile patients
30. Heat stress cause testicular germ cell apoptosis in adult mice
31. Cellular defenses against damage from reactive oxygen species
32. Free radicals and myocardial injury: Pharmacologic implications