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Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 18, 2004, Pages 4719-4722

Potent antitumor N-mustard derivatives of 9-anilinoacridine, synthesis and antitumor evaluation

(7) Bacherikov, Valeriy A a Chou, Ting Chao b Dong, Hua Jin b Chen, Ching Huang a Lin, Yi Wen a Tsai, Tsong Jen a Su, Tsann Long a

a INSTITUTE OF BIOMEDICAL SCIENCES (Taiwan)

b MEMORIAL SLOAN KETTERING CANCER CENTER (United States)

Author keywords

Acridines; Alkylating agents; Antitumor compounds; Chemotherapy; Synthesis

Indexed keywords

3 (9 ACRIDINYLAMINO) 5 HYDROXYMETHYLANILINE; 9 ANILINOACRIDINE DERIVATIVE; ANILINE DERIVATIVE; ANTINEOPLASTIC AGENT; PACLITAXEL; UNCLASSIFIED DRUG; VINBLASTINE;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER CELL; CANCER RESISTANCE; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LYMPHATIC LEUKEMIA; MOUSE; NONHUMAN;

AMSACRINE; ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; HUMANS; INJECTIONS, INTRAVENOUS; MICE; MICE, NUDE; NITROGEN MUSTARD COMPOUNDS; PACLITAXEL; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; VINBLASTINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS MUSCULUS;

EID: 8544242717 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2004.06.080 Document Type: Article

Times cited : (35)

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