Aniline mustard analogues of the DNA-intercalating agent amsacrine: DNA interaction and biological activity

Anti-Cancer Drug Design

Volumn 12, Issue 3, 1997, Pages 181-203

  Fan, Jun Yao ^a   Valu, Kisione K ^a   Woodgate, Paul D ^a   Baguley, Bruce C ^a   Denny, William A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

9 anilinoacridine; Amsacrine; DNA intercalator; DNA targeted alkylator; Gel electrophoresis; Nitrogen mustard

Indexed keywords

4 [4 [N [3 [4 (N,N BIS(2 CHLOROETHYL)AMINO]PHENYL]PROPYL]CARBOXAMIDO] 9 ACRIDINYLAMINO] 3 METHOXYMETHANESULFONANILIDE; ADENINE; AMSACRINE DERIVATIVE; ANILINE MUSTARD DERIVATIVE; ANTILEUKEMIC AGENT; DNA; GUANINE; N [3 METHOXY 4 (9 ACRIDINYLAMINO)PHENYL] 3 [4 (N,N BIS(2 CHLOROETHYL)AMINO]PHENOXY]PROPANAMIDE; N [3 METHOXY 4 (9 ACRIDINYLAMINO)PHENYL] 3 [4 (N,N BIS(2 CHLOROETHYL)AMINO]SULFONYLPHENYL]PROPANAMIDE; N [3 METHOXY 4 (9 ACRIDINYLAMINO)PHENYL] 3 [4 (N,N BIS(2 CHLOROETHYL)AMINO]THIOPHENYL]PROPANAMIDE; N [3 METHOXY 4 (9 ACRIDINYLAMINO)PHENYL] 4 [4 (N,N BIS(2 CHLOROETHYL)AMINO]PHENYL]BUTANAMIDE; N [3 METHOXY 4 [4 [N [3 [4 [N,N BIS(2 CHLOROETHYL)AMINO]PHENYL]PROPYL]CARBOXAMIDO] 9 ACRIDINYLAMINO]PHENYL]ACETAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA ALKYLATION; DNA CLEAVAGE; DNA CROSS LINKING; DNA FOOTPRINTING; DRUG DNA INTERACTION; DRUG SYNTHESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; BRASSICACEAE;

EID: 0030900965     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

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