메뉴 건너뛰기




Volumn 3, Issue 1, 2016, Pages 15-21

Carbapenem resistance: overview of the problem and future perspectives

Author keywords

antibiotic resistance; carbapenemases; carbapenems

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; CLAVULANIC ACID; DAPTOMYCIN; FOSFOMYCIN; MEROPENEM; METALLO BETA LACTAMASE; PENICILLIN DERIVATIVE; POLYMYXIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TAZOBACTAM;

EID: 85140806063     PISSN: 20499361     EISSN: 2049937X     Source Type: Journal    
DOI: 10.1177/2049936115621709     Document Type: Review
Times cited : (490)

References (62)
  • 1
    • 84886901842 scopus 로고    scopus 로고
    • Higher incidence of acute kidney injury with intravenous colistimethate sodium compared with polymyxin B in critically ill patients at a tertiary care medical center
    • D.AkajagborS.WilsonK.Shere-WolfeP.DakumM.CharuratB.Gilliam (2013) Higher incidence of acute kidney injury with intravenous colistimethate sodium compared with polymyxin B in critically ill patients at a tertiary care medical center. Clin Infect Dis57: 1300–1303.
    • (2013) Clin Infect Dis , vol.57 , pp. 1300-1303
    • Akajagbor, D.1    Wilson, S.2    Shere-Wolfe, K.3    Dakum, P.4    Charurat, M.5    Gilliam, B.6
  • 3
    • 33747625237 scopus 로고    scopus 로고
    • Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa
    • R.BonomoD.Szabo (2006) Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa. Clin Infect Dis43: S49–S56.
    • (2006) Clin Infect Dis , vol.43 , pp. S49-S56
    • Bonomo, R.1    Szabo, D.2
  • 7
    • 79952353954 scopus 로고    scopus 로고
    • Early dissemination of NDM-1- and OXA-181-producing Enterobacteriaceae in Indian hospitals: report from the SENTRY Antimicrobial Surveillance Program, 2006–2007
    • M.CastanheiraL.DeshpandeD.MathaiJ.BellR.JonesR.Mendes (2011) Early dissemination of NDM-1- and OXA-181-producing Enterobacteriaceae in Indian hospitals: report from the SENTRY Antimicrobial Surveillance Program, 2006–2007. Antimicrob Agents Chemother55: 1274–1278.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1274-1278
    • Castanheira, M.1    Deshpande, L.2    Mathai, D.3    Bell, J.4    Jones, R.5    Mendes, R.6
  • 8
    • 9644289421 scopus 로고    scopus 로고
    • Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase
    • M.CastanheiraM.TolemanR.JonesF.SchmidtT.Walsh (2004) Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase. Antimicrob Agents Chemother48: 4654–4661.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 4654-4661
    • Castanheira, M.1    Toleman, M.2    Jones, R.3    Schmidt, F.4    Walsh, T.5
  • 9
    • 85140803737 scopus 로고    scopus 로고
    • CDC (2013) Antibiotic Resistance Threats to the United States. Atlanta, GA: Centers for Disease Control and Prevention. www.cdc.gov/drugresistance/threat-report-2013/index.html (accessed 10 September 2015)
  • 10
    • 77953024136 scopus 로고    scopus 로고
    • Plasmid-mediated carbapenem-hydrolysing OXA-48-lactamase in Klebsiella pneumoniae from Tunisia
    • G.CuzonT.NaasA.LesenneM.BenhamouP.Nordmann (2010) Plasmid-mediated carbapenem-hydrolysing OXA-48-lactamase in Klebsiella pneumoniae from Tunisia. Int J Antimicrob Agents36: 91–93.
    • (2010) Int J Antimicrob Agents , vol.36 , pp. 91-93
    • Cuzon, G.1    Naas, T.2    Lesenne, A.3    Benhamou, M.4    Nordmann, P.5
  • 11
    • 84899511797 scopus 로고    scopus 로고
    • Worldwide dissemination of the NDM-type carbapenemases in Gram-negative bacteria
    • L.DortetL.PoirelP.Nordmann (2014) Worldwide dissemination of the NDM-type carbapenemases in Gram-negative bacteria. Biomed Res Int2014: 249856.
    • (2014) Biomed Res Int , vol.2014 , pp. 249856
    • Dortet, L.1    Poirel, L.2    Nordmann, P.3
  • 12
    • 60649091495 scopus 로고    scopus 로고
    • Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the eastern U. S. A
    • A.EndimianiA.HujerF.PerezC.BethelK. HujerJ.Kroeger (2009) Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the eastern U. S. A. J Antimicrob Chemother63: 427–437.
    • (2009) J Antimicrob Chemother , vol.63 , pp. 427-437
    • Endimiani, A.1    Hujer, A.2    Perez, F.3    Bethel, C.4    Hujer, K.5    Kroeger, J.6
  • 13
    • 72149117149 scopus 로고    scopus 로고
    • Fosfomycin for the treatment of multidrug-resistant, including extended-spectrum beta-lactamase producing, Enterobacteriaceae infections: a systematic review
    • M.FalagasA.KastorisA.KapaskelisD.Karageorgopoulos (2010) Fosfomycin for the treatment of multidrug-resistant, including extended-spectrum beta-lactamase producing, Enterobacteriaceae infections: a systematic review. Lancet Infect Dis10: 43–50.
    • (2010) Lancet Infect Dis , vol.10 , pp. 43-50
    • Falagas, M.1    Kastoris, A.2    Kapaskelis, A.3    Karageorgopoulos, D.4
  • 14
    • 0033840253 scopus 로고    scopus 로고
    • IBC-1, a novel integron-associated class A beta-lactamase with extended-spectrum properties produced by an Enterobacter cloacae clinical strain
    • P.GiakkoupiL.TzouvelekisA.TsakrisV. LoukovaD.SofianouE.Tzelepi (2000) IBC-1, a novel integron-associated class A beta-lactamase with extended-spectrum properties produced by an Enterobacter cloacae clinical strain. Antimicrob Agents Chemother44: 2247–2253.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2247-2253
    • Giakkoupi, P.1    Tzouvelekis, L.2    Tsakris, A.3    Loukova, V.4    Sofianou, D.5    Tzelepi, E.6
  • 16
    • 2542499764 scopus 로고    scopus 로고
    • Molecular characterization of a carbapenem-hydrolyzing class A beta-lactamase, SFC-1, from Serratia fonticola UTAD54
    • I.HenriquesA.MouraA.AlvesM.SaavedraA.Correia (2004) Molecular characterization of a carbapenem-hydrolyzing class A beta-lactamase, SFC-1, from Serratia fonticola UTAD54. Antimicrob Agents Chemother48: 2321–2324.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2321-2324
    • Henriques, I.1    Moura, A.2    Alves, A.3    Saavedra, M.4    Correia, A.5
  • 18
    • 70349321618 scopus 로고    scopus 로고
    • Regional dissemination of KPC-producing Klebsiella pneumoniae
    • B.KitchelD.SundinJ.Patel (2009) Regional dissemination of KPC-producing Klebsiella pneumoniae. Antimicrob Agents Chemother53: 4511–4513.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 4511-4513
    • Kitchel, B.1    Sundin, D.2    Patel, J.3
  • 19
    • 0032587031 scopus 로고    scopus 로고
    • Cloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate
    • L.LaurettiM.RiccioA.MazzariolG.CornagliaG.AmicosanteR.Fontana (1999) Cloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate. Antimicrob Agents Chemother43: 1584–1590.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1584-1590
    • Lauretti, L.1    Riccio, M.2    Mazzariol, A.3    Cornaglia, G.4    Amicosante, G.5    Fontana, R.6
  • 21
    • 27644562636 scopus 로고    scopus 로고
    • Novel acquired metallo-beta-lactamase gene, bla(SIM-1), in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea
    • K.LeeJ.YumD.YongH.LeeH.KimJ.Docquier (2005) Novel acquired metallo-beta-lactamase gene, bla(SIM-1), in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea. Antimicrob Agents Chemother49: 4485–4491.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 4485-4491
    • Lee, K.1    Yum, J.2    Yong, D.3    Lee, H.4    Kim, H.5    Docquier, J.6
  • 23
    • 84930509467 scopus 로고    scopus 로고
    • Why should governments invest in antibiotic drug discovery against multi-drug-resistant bacteria?
    • G.Meletis (2014) Why should governments invest in antibiotic drug discovery against multi-drug-resistant bacteria?Recent Pat Antiinfect Drug Discov9: 150.
    • (2014) Recent Pat Antiinfect Drug Discov , vol.9 , pp. 150
    • Meletis, G.1
  • 24
    • 84937970198 scopus 로고    scopus 로고
    • Double- and multi-carbapenemase-producers: the excessively armored bacilli of the current decade
    • G.MeletisD.ChatzidimitriouN.Malisiovas (2015a) Double- and multi-carbapenemase-producers: the excessively armored bacilli of the current decade. Eur J Clin Microbiol Infect Dis34: 1487–1493.
    • (2015) Eur J Clin Microbiol Infect Dis , vol.34 , pp. 1487-1493
    • Meletis, G.1    Chatzidimitriou, D.2    Malisiovas, N.3
  • 25
    • 84876523461 scopus 로고    scopus 로고
    • Mechanisms responsible for the emergence of carbapenem resistance in Pseudomonas aeruginosa
    • G.MeletisM.ExindariN.VavatsiD.SofianouE.Diza (2012) Mechanisms responsible for the emergence of carbapenem resistance in Pseudomonas aeruginosa. Hippokratia16: 303–307.
    • (2012) Hippokratia , vol.16 , pp. 303-307
    • Meletis, G.1    Exindari, M.2    Vavatsi, N.3    Sofianou, D.4    Diza, E.5
  • 26
    • 84904260856 scopus 로고    scopus 로고
    • Carbapenemase reports from the Balkans: a systematic review
    • G.MeletisE.OustasM.Bagkeri (2014a) Carbapenemase reports from the Balkans: a systematic review. Infez Med22: 85–106.
    • (2014) Infez Med , vol.22 , pp. 85-106
    • Meletis, G.1    Oustas, E.2    Bagkeri, M.3
  • 27
    • 84940500860 scopus 로고    scopus 로고
    • Containment of carbapenem resistance rates of Klebsiella pneumoniae and Acinetobacter baumannii in a Greek hospital with a concomitant increase in colistin, gentamicin and tigecycline resistance
    • G.MeletisE.OustasC.BotzioriE.KakasiA.Koteli (2015b) Containment of carbapenem resistance rates of Klebsiella pneumoniae and Acinetobacter baumannii in a Greek hospital with a concomitant increase in colistin, gentamicin and tigecycline resistance. New Microbiol38: 417–421.
    • (2015) New Microbiol , vol.38 , pp. 417-421
    • Meletis, G.1    Oustas, E.2    Botziori, C.3    Kakasi, E.4    Koteli, A.5
  • 29
    • 79959761678 scopus 로고    scopus 로고
    • The challenges of antimicrobial drug resistance in Greece
    • S.MiyakisA.PefanisA.Tsakris (2011) The challenges of antimicrobial drug resistance in Greece. Clin Infect Dis53: 177–184.
    • (2011) Clin Infect Dis , vol.53 , pp. 177-184
    • Miyakis, S.1    Pefanis, A.2    Tsakris, A.3
  • 31
    • 84978328513 scopus 로고    scopus 로고
    • Treatment options for carbapenem-resistant Enterobacteriaceae infections
    • H.MorrillJ.PogueK.KayeK.LaPlante (2015) Treatment options for carbapenem-resistant Enterobacteriaceae infections. Open Forum Infect Dis2: ofv050.
    • (2015) Open Forum Infect Dis , vol.2 , pp. ofv050
    • Morrill, H.1    Pogue, J.2    Kaye, K.3    LaPlante, K.4
  • 32
    • 62749195559 scopus 로고    scopus 로고
    • The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria
    • P.NordmannG.CuzonT.Naas (2009) The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis9: 228–236.
    • (2009) Lancet Infect Dis , vol.9 , pp. 228-236
    • Nordmann, P.1    Cuzon, G.2    Naas, T.3
  • 36
    • 0033998662 scopus 로고    scopus 로고
    • Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae
    • L.PoirelI.Le ThomasT.NaasA.KarimP.Nordmann (2000) Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae. Antimicrob Agents Chemother44: 622–632.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 622-632
    • Poirel, L.1    Le Thomas, I.2    Naas, T.3    Karim, A.4    Nordmann, P.5
  • 37
    • 35348905611 scopus 로고    scopus 로고
    • Carbapenemases: molecular diversity and clinical consequences
    • L.PoirelJ.PitoutP.Nordmann (2007) Carbapenemases: molecular diversity and clinical consequences. Future Microbiol2: 501–512.
    • (2007) Future Microbiol , vol.2 , pp. 501-512
    • Poirel, L.1    Pitout, J.2    Nordmann, P.3
  • 39
    • 77952623381 scopus 로고    scopus 로고
    • Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands
    • L.PoirelJ.Rodríguez-MartínezN.Al NaiemiY.Debets-OssenkoppP.Nordmann (2010) Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands. Antimicrob Agents Chemother54: 2420–2424.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 2420-2424
    • Poirel, L.1    Rodríguez-Martínez, J.2    Al Naiemi, N.3    Debets-Ossenkopp, Y.4    Nordmann, P.5
  • 41
    • 81255185222 scopus 로고    scopus 로고
    • European dissemination of a single OXA-48-producing Klebsiella pneumoniae clone
    • A.PotronJ.KalpoeL.PoirelP.Nordmann (2011) European dissemination of a single OXA-48-producing Klebsiella pneumoniae clone. Clin Microbiol Infect17: E24–E26.
    • (2011) Clin Microbiol Infect , vol.17 , pp. E24-E26
    • Potron, A.1    Kalpoe, J.2    Poirel, L.3    Nordmann, P.4
  • 42
    • 33646453620 scopus 로고    scopus 로고
    • Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates
    • J.QualeS.BratuJ.GuptaD.Landman (2006) Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother50: 1633–1641.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1633-1641
    • Quale, J.1    Bratu, S.2    Gupta, J.3    Landman, D.4
  • 43
    • 34547422759 scopus 로고    scopus 로고
    • Carbapenemases: the versatile beta-lactamases
    • A.QueenanK.Bush (2007) Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev20: 440–458.
    • (2007) Clin Microbiol Rev , vol.20 , pp. 440-458
    • Queenan, A.1    Bush, K.2
  • 44
    • 84864609500 scopus 로고    scopus 로고
    • Klebsiella pneumoniae carbapenemases in Enterobacteriaceae: history, evolution, and microbiology concerns
    • R.RappC.Urban (2012) Klebsiella pneumoniae carbapenemases in Enterobacteriaceae: history, evolution, and microbiology concerns. Pharmacotherapy32: 399–407.
    • (2012) Pharmacotherapy , vol.32 , pp. 399-407
    • Rapp, R.1    Urban, C.2
  • 45
    • 79953875949 scopus 로고    scopus 로고
    • The challenges of antimicrobial resistance in Brazil
    • F.Rossi (2011) The challenges of antimicrobial resistance in Brazil. Clin Infect Dis52: 1138–1143.
    • (2011) Clin Infect Dis , vol.52 , pp. 1138-1143
    • Rossi, F.1
  • 46
    • 84896978278 scopus 로고    scopus 로고
    • Variation in potency and spectrum of tigecycline activity against bacterial strains from U.S. medical centers since its approval for clinical use (2006 to 2012)
    • H.SaderD.FarrellR.FlammR.Jones (2014) Variation in potency and spectrum of tigecycline activity against bacterial strains from U.S. medical centers since its approval for clinical use (2006 to 2012). Antimicrob Agents Chemother58: 2274–2280.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 2274-2280
    • Sader, H.1    Farrell, D.2    Flamm, R.3    Jones, R.4
  • 47
    • 84937138142 scopus 로고    scopus 로고
    • Antibiotic resistance in the opportunistic pathogen Stenotrophomonas maltophilia
    • M.Sánchez (2015) Antibiotic resistance in the opportunistic pathogen Stenotrophomonas maltophilia. Front Microbiol6: 658.
    • (2015) Front Microbiol , vol.6 , pp. 658
    • Sánchez, M.1
  • 48
    • 0346694551 scopus 로고    scopus 로고
    • Efflux as a mechanism of resistance to antimicrobials in Pseudomonas aeruginosa and related bacteria: unanswered questions
    • H.Schweizer (2003) Efflux as a mechanism of resistance to antimicrobials in Pseudomonas aeruginosa and related bacteria: unanswered questions. Genet Mol Res2: 48–62.
    • (2003) Genet Mol Res , vol.2 , pp. 48-62
    • Schweizer, H.1
  • 50
    • 84867166640 scopus 로고    scopus 로고
    • Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions
    • L.TzouvelekisA.MarkogiannakisM.PsichogiouP.TassiosG.Daikos (2012) Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions. Clin Microbiol Rev25: 682–707.
    • (2012) Clin Microbiol Rev , vol.25 , pp. 682-707
    • Tzouvelekis, L.1    Markogiannakis, A.2    Psichogiou, M.3    Tassios, P.4    Daikos, G.5
  • 51
    • 33746933470 scopus 로고    scopus 로고
    • First detection of the plasmid-mediated class A carbapenemase KPC-2 in clinical isolates of Klebsiella pneumoniae from South America
    • M.VillegasK.LolansA.CorreaC.SuarezJ.LopezM.Vallejo (2006) First detection of the plasmid-mediated class A carbapenemase KPC-2 in clinical isolates of Klebsiella pneumoniae from South America. Antimicrob Agents Chemother50: 2880–2882.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2880-2882
    • Villegas, M.1    Lolans, K.2    Correa, A.3    Suarez, C.4    Lopez, J.5    Vallejo, M.6
  • 52
    • 78649697323 scopus 로고    scopus 로고
    • Emerging carbapenemases: a global perspective
    • T.Walsh (2010) Emerging carbapenemases: a global perspective. Int J Antimicrob Agents36: S8–S14.
    • (2010) Int J Antimicrob Agents , vol.36 , pp. S8-S14
    • Walsh, T.1
  • 58
    • 84869237356 scopus 로고    scopus 로고
    • Genetic and biochemical characterization of an acquired subgroup B3 metallo-β-lactamase gene, blaAIM-1, and its unique genetic context in Pseudomonas aeruginosa from Australia
    • D.YongM.TolemanJ.BellB.RitchieR.PrattH.Ryley (2012) Genetic and biochemical characterization of an acquired subgroup B3 metallo-β-lactamase gene, blaAIM-1, and its unique genetic context in Pseudomonas aeruginosa from Australia. Antimicrob Agents Chemother56: 6154–6159.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 6154-6159
    • Yong, D.1    Toleman, M.2    Bell, J.3    Ritchie, B.4    Pratt, R.5    Ryley, H.6
  • 59
    • 71249134038 scopus 로고    scopus 로고
    • Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India
    • D.YongM.TolemanC.GiskeH.ChoK.SundmanK.Lee (2009) Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob Agents Chemother53: 5046–5054.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 5046-5054
    • Yong, D.1    Toleman, M.2    Giske, C.3    Cho, H.4    Sundman, K.5    Lee, K.6
  • 60
    • 84939486487 scopus 로고    scopus 로고
    • The β-lactams strike back: ceftazidime-avibactam
    • E.ZasowskiJ.RybakM.Rybak (2015) The β-lactams strike back: ceftazidime-avibactam. Pharmacotherapy35: 755–770.
    • (2015) Pharmacotherapy , vol.35 , pp. 755-770
    • Zasowski, E.1    Rybak, J.2    Rybak, M.3
  • 61
    • 79953298441 scopus 로고    scopus 로고
    • Epidemiology and genetics of VIM-type metallo-β-lactamases in Gram-negative bacilli
    • W.ZhaoZ.Hu (2011a) Epidemiology and genetics of VIM-type metallo-β-lactamases in Gram-negative bacilli. Future Microbiol6: 317–333.
    • (2011) Future Microbiol , vol.6 , pp. 317-333
    • Zhao, W.1    Hu, Z.2
  • 62
    • 79959708014 scopus 로고    scopus 로고
    • IMP-type metallo-β-lactamases in Gram-negative bacilli: distribution, phylogeny, and association with integrons
    • W.ZhaoZ.Hu (2011b) IMP-type metallo-β-lactamases in Gram-negative bacilli: distribution, phylogeny, and association with integrons. Crit Rev Microbiol37: 214–226.
    • (2011) Crit Rev Microbiol , vol.37 , pp. 214-226
    • Zhao, W.1    Hu, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.