Host Characteristics and Bacterial Traits Predict Experimental Virulence for Escherichia coli Bloodstream Isolates from Patients with Urosepsis

Open Forum Infectious Diseases

Volumn 2, Issue 3, 2015, Pages

  Johnson, James R ^a   Porter, Stephen ^a   Johnston, Brian ^a   Kuskowski, Michael A ^a   Spurbeck, Rachel R ^b   Mobley, Harry L T ^b   Williamson, Deborah A ^c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Escherichia coli infections; Galleria mellonella; host compromise; insect model; mouse model; phylogenetic group urosepsis; sepsis; virulence; virulence factors; virulence genes

Indexed keywords

EID: 85132969078     PISSN: None     EISSN: 23288957     Source Type: Journal    
DOI: 10.1093/OFID/OFV083     Document Type: Article

References (25)

1. Russo TA, Johnson JR. Medical and economic impact of extraintestinal infections due to Escherichia coli: an overlooked epidemic. Microbes Infect 2003; 5:449–56.
2. Russo TA, Johnson JR. A proposal for an inclusive designation for extraintestinal pathogenic Escherichia coli: ExPEC. J Infect Dis 2000; 181:1753–4.
3. Kudinha T, Johnson JR, Andrew SD, et al. Distribution of phylogenetic groups, sequence type ST131, and virulence-associated traits among Escherichia coli isolates from men with pyelonephritis or cystitis and healthy controls. Clin Microbiol Infect 2013; 19:E173–80.
4. Yamamoto S, Tsukamoto T, Terai A, et al. Genetic evidence supporting the fecal-perineal-urethral hypothesis in cystitis caused by Escherichia coli. J Urol 1997; 157:1127–9.
5. Bert F, Panhard X, Johnson JR, et al. Genetic background of Escherichia coli isolates from patients with spontaneous bacterial peritonitis: relationship with host factors and prognosis. Clin Microbiol Infect 2008; 14:1034–50.
6. Johnson JR. papG alleles among Escherichia coli strains causing urosepsis: associations with other bacterial characteristics and host compromise. Infect Immun 1998; 66:4568–71.
7. Johnson JR, Orskov I, Orskov F, et al. O, K, and H antigens predict virulence factors, carboxylesterase B pattern, antimicrobial resistance, and host compromise among Escherichia coli strains causing urosepsis. J Infect Dis 1994; 169:119–26.
8. Picard B, Sevali Garcia J, Gouriou S, et al. The link between phylogeny and virulence in Escherichia coli extraintestinal infection. Infect Immun 1999; 67:546–53.
9. Johnson JR, Clermont O, Menard M, et al. Experimental mouse lethality of Escherichia coli isolates, in relation to accessory traits, phylogenetic group, and ecological source. J Infect Dis 2006; 194:1141–50.
10. Johnson JR, Porter SB, Zhanel G, et al. Virulence of Escherichia coli clinical isolates in a murine sepsis model in relation to sequence type ST131 status, fluoroquinolone resistance, and virulence genotype. Infect Immun 2012; 80:1554–62.
11. Mora A, Dahbi G, López C, et al. Virulence patterns in a murine sepsis model of ST131 Escherichia coli clinical isolates belonging to serotypes O25b:H4 and O16:H5 are associated to specific virotypes. PLoS One 2014; 9:e87025.
12. Williamson DA, Millis G, Johnson JR, et al. In vivo correlates of molecularly inferred virulence among extraintestinal pathogenic Escherichia coli (ExPEC) in the wax moth Galleria mellonella model system. Virulence 2014; 5:388–93.
13. Johnson JR, Roberts P, Stamm WE. P fimbriae and other virulence factors in Escherichia coli urosepsis: association with patient’s characteristics. J Infect Dis 1987; 156:225–9.
14. Johnson JR, Moseley S, Roberts P, Stamm WE. Aerobactin and other virulence factor genes among strains of Escherichia coli causing urosepsis: association with patient characteristics. Infect Immun 1988; 56:405–12.
15. Johnson JR, Goullet PH, Picard B, et al. Association of carboxylesterase B electrophoretic pattern with presence and expression of urovirulence factor determinants and antimicrobial resistance among strains of Escherichia coli causing urosepsis. Infect Immun 1991; 59:2311–5.
16. E. coli, among Escherichia coli isolates from patients with urosepsis. Infect Immun 2000; 68:3040–7.
17. Johnson JR, Stell A. Errata: Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise. J Infect Dis 2000; 181:2122.
18. Johnson JR, Stell AL. Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise. J Infect Dis 2000; 181:261–72.
19. Clermont O, Christenson JK, Denamur E, Gordon DM. The Clermont Escherichia coli phylo-typing method revisited: improvement of specificity and detection of new phylo-groups. Environ Microbiol Rep 2012; 5:58–65.
20. Johnson JR, Murray AC, Gajewski A, et al. Isolation and molecular characterization of nalidixic acid-resistant extraintestinal pathogenic Escherichia coli from retail chicken products. Antimicrob Agents Chemother 2003; 47:2161–8.
21. Spurbeck RR, Dinh PC, Walk ST, et al. Escherichai coli isolates that carry vat, fyuA, chuA, and yfcV efficiently colonize the urinary tract. Infect Immun 2012; 80:4115–22.
22. Campbell I. Chi-squared and Fisher-Irwin tests of two-by-two tables with small sample recommendations. Statist Med 2007; 26:3661–75.
23. Gleckman R, Blagg N, Gibert D, et al. Community-acquired bacteremic urosepsis in the elderly patients: a prospective study of 34 consecutive episodes. J Urol 1982; 128:79–81.
24. Armitage KB, Salata RA, Landefeld CS. Urosepsis in the elderly: clinical and microbiologic characteristics. Infect Dis Clin Prac 1993; 2:260–6.
25. Johnson JR, Scheutz F, Ulleryd P, et al. Host-pathogen relationships among Escherichia coli isolates from men with febrile urinary tract infection. Clin Infect Dis 2005; 40:813–22.