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Volumn 2, Issue 1, 2014, Pages

Big data and clinicians: A review on the state of the science

Author keywords

Big data; Clinical research; Database; Medical informatics; Medicine

Indexed keywords


EID: 85097571242     PISSN: None     EISSN: 22919694     Source Type: Journal    
DOI: 10.2196/medinform.2913     Document Type: Review
Times cited : (125)

References (113)
  • 1
    • 0027015006 scopus 로고
    • Visualization of large datasets in intensive care
    • [FREE Full text] [Medline: 1482864]
    • Wenkebach U, Pollwein B, Finsterer U. Visualization of large datasets in intensive care. Proc Annu Symp Comput Appl Med Care 1992:18-22 [FREE Full text] [Medline: 1482864].
    • (1992) Proc Annu Symp Comput Appl Med Care , pp. 18-22
    • Wenkebach, U1    Pollwein, B2    Finsterer, U.3
  • 2
    • 84863247572 scopus 로고    scopus 로고
    • A distributed big data storage and data mining framework for solar-generated electricity quantity forecasting
    • [FREE Full text] [doi]
    • Wang J, Chen Y, Hua R, Wang P, Fu J. A distributed big data storage and data mining framework for solar-generated electricity quantity forecasting. Proc. SPIE 8333, Photonics and Optoelectronics Meetings (POEM) 2011 [FREE Full text] [doi: 10.1117/12.919640].
    • (2011) Proc. SPIE 8333, Photonics and Optoelectronics Meetings (POEM)
    • Wang, J1    Chen, Y2    Hua, R3    Wang, P4    Fu, J.5
  • 3
    • 84863247572 scopus 로고    scopus 로고
    • A distributed big data storage and data mining framework for solar-generated electricity quantity forecasting
    • 2011 [FREE Full text] [doi]
    • Wang JZ, Chen YJ, Hua R, Wang P, Fu J. A distributed big data storage and data mining framework for solar-generated electricity quantity forecasting. Proc. SPIE 8333, Photonics and Optoelectronics Meetings (POEM) 2011 2011 [FREE Full text] [doi: 10.1117/12.919640].
    • (2011) Proc. SPIE 8333, Photonics and Optoelectronics Meetings (POEM)
    • Wang, JZ1    Chen, YJ2    Hua, R3    Wang, P4    Fu, J.5
  • 4
    • 84864975150 scopus 로고    scopus 로고
    • Distributed storage system big data mining based on HPC application-A solar photovoltaic forecasting system practice
    • Fu J, Chen ZH, Wang JC, He MQ, Wang JZ. Distributed storage system big data mining based on HPC application-A solar photovoltaic forecasting system practice. Information-Tokyo 2012;15(9):3749-3755.
    • (2012) Information-Tokyo , vol.15 , Issue.9 , pp. 3749-3755
    • Fu, J1    Chen, ZH2    Wang, JC3    He, MQ4    Wang, JZ.5
  • 5
    • 67349111264 scopus 로고    scopus 로고
    • Large-scale electrophysiology: Acquisition, compression, encryption, and storage of big data
    • [FREE Full text] [doi] [Medline: 19427545]
    • Brinkmann BH, Bower MR, Stengel KA, Worrell GA, Stead M. Large-scale electrophysiology: Acquisition, compression, encryption, and storage of big data. J Neurosci Methods 2009;180(1):185-192 [FREE Full text] [doi: 10.1016/j.jneumeth.2009.03.022] [Medline: 19427545].
    • (2009) J Neurosci Methods , vol.180 , Issue.1 , pp. 185-192
    • Brinkmann, BH1    Bower, MR2    Stengel, KA3    Worrell, GA4    Stead, M.5
  • 6
    • 51349115095 scopus 로고    scopus 로고
    • Big data: The future of biocuration
    • [FREE Full text] [doi] [Medline: 18769432]
    • Howe D, Costanzo M, Fey P, Gojobori T, Hannick L, Hide W, et al. Big data: The future of biocuration. Nature 2008;455(7209):47-50 [FREE Full text] [doi: 10.1038/455047a] [Medline: 18769432].
    • (2008) Nature , vol.455 , Issue.7209 , pp. 47-50
    • Howe, D1    Costanzo, M2    Fey, P3    Gojobori, T4    Hannick, L5    Hide, W6
  • 7
    • 83755196634 scopus 로고    scopus 로고
    • Collection and curation of a large reference dataset for activity recognition
    • [doi]
    • Calatroni A, Roggen D, Troster G. Collection and curation of a large reference dataset for activity recognition. Ieee Sys Man Cybern 2011 2011:30-35. [doi: 10.1109/ICSMC.2011.6083638].
    • (2011) Ieee Sys Man Cybern , vol.2011 , pp. 30-35
    • Calatroni, A1    Roggen, D2    Troster, G.3
  • 8
    • 84883788980 scopus 로고    scopus 로고
    • 'Big data', Hadoop and cloud computing in genomics
    • [doi] [Medline: 23872175]
    • O'Driscoll A, Daugelaite J, Sleator RD. 'Big data', Hadoop and cloud computing in genomics. J Biomed Inform 2013;46(5):774-781. [doi: 10.1016/j.jbi.2013.07.001] [Medline: 23872175].
    • (2013) J Biomed Inform , vol.46 , Issue.5 , pp. 774-781
    • O'Driscoll, A1    Daugelaite, J2    Sleator, RD.3
  • 9
    • 84875115346 scopus 로고    scopus 로고
    • Alternatives to relational database: Comparison of NoSQL and XML approaches for clinical data storage
    • [doi] [Medline: 23177219]
    • Lee KK, Tang WC, Choi KS. Alternatives to relational database: Comparison of NoSQL and XML approaches for clinical data storage. Comput Methods Programs Biomed 2013;110(1):99-109. [doi: 10.1016/j.cmpb.2012.10.018] [Medline: 23177219].
    • (2013) Comput Methods Programs Biomed , vol.110 , Issue.1 , pp. 99-109
    • Lee, KK1    Tang, WC2    Choi, KS.3
  • 12
    • 0017132860 scopus 로고
    • Two-way pattern analysis of a large data set to evaluate genotypic adaptation
    • [doi]
    • Byth DE, Eisemann RL, de Lacy IH. Two-way pattern analysis of a large data set to evaluate genotypic adaptation. Heredity 1976;37(2):215-230. [doi: 10.1038/Hdy.1976.84].
    • (1976) Heredity , vol.37 , Issue.2 , pp. 215-230
    • Byth, DE1    Eisemann, RL2    de Lacy, IH.3
  • 13
    • 0015599858 scopus 로고
    • A new modification of the Redlich-Kwong equation of state based on the analysis of a large set of pure component data
    • [doi]
    • Chaudron J, Assenlineau L, Renon H. A new modification of the Redlich-Kwong equation of state based on the analysis of a large set of pure component data. Chemical Engineering Science 1973;28(3):839-846. [doi: 10.1016/0009-2509(77)80018-3].
    • (1973) Chemical Engineering Science , vol.28 , Issue.3 , pp. 839-846
    • Chaudron, J1    Assenlineau, L2    Renon, H.3
  • 14
    • 0025054403 scopus 로고
    • Dealing with large data sets
    • [Medline: 2247031]
    • Graefe JF, Wood RW. Dealing with large data sets. Neurotoxicol Teratol 1990;12(5):449-454. [Medline: 2247031].
    • (1990) Neurotoxicol Teratol , vol.12 , Issue.5 , pp. 449-454
    • Graefe, JF1    Wood, RW.2
  • 15
    • 84872047667 scopus 로고    scopus 로고
    • Big data
    • [Medline: 23167038]
    • Ackerman MJ. Big data. J Med Pract Manage 2012;28(2):153-154. [Medline: 23167038].
    • (2012) J Med Pract Manage , vol.28 , Issue.2 , pp. 153-154
    • Ackerman, MJ.1
  • 16
    • 79951811877 scopus 로고    scopus 로고
    • Big data, but are we ready?
    • Mar; [doi] [Medline: 21301471]
    • Trelles O, Prins P, Snir M, Jansen RC. Big data, but are we ready? Nat Rev Genet 2011 Mar;12(3):224. [doi: 10.1038/nrg2857-c1] [Medline: 21301471].
    • (2011) Nat Rev Genet , vol.12 , Issue.3 , pp. 224
    • Trelles, O1    Prins, P2    Snir, M3    Jansen, RC.4
  • 17
    • 84943794051 scopus 로고    scopus 로고
    • analysis ATK. 2013URL: [accessed 2013-11-25] [WebCite Cache ID 6LOmyDbvg]
    • analysis ATK. Big Data and the Creative Destruction of Today's Business Models. 2013URL: Http://www.atkearney.com/strategic-it/ideas-insights/article/-/asset-publisher/LCcgOeS4t85g/content/big-data-and-the-creative-destruction-of-today-s-business-models/10192 [accessed 2013-11-25] [WebCite Cache ID 6LOmyDbvg].
    • Big Data and the Creative Destruction of Today's Business Models
  • 19
    • 77957921110 scopus 로고    scopus 로고
    • Probabilistic analysis of a large-scale urban traffic sensor data set
    • [doi]
    • Hutchins J, Ihler A, Smyth P. Probabilistic analysis of a large-scale urban traffic sensor data set. Knowledge Discovery from Sensor Data 2010;5840:94-114. [doi: 10.1007/978-3-642-12519-5-6].
    • (2010) Knowledge Discovery from Sensor Data , vol.5840 , pp. 94-114
    • Hutchins, J1    Ihler, A2    Smyth, P.3
  • 20
    • 33750971424 scopus 로고    scopus 로고
    • Regional simulation of long-term organic carbon stock changes in cropland soils using the DNDC model: 1. Large-scale model validation against a spatially explicit data set
    • [doi]
    • Sleutel S, De Neve S, Beheydt D, Li C, Hofman G. Regional simulation of long-term organic carbon stock changes in cropland soils using the DNDC model: 1. Large-scale model validation against a spatially explicit data set. Soil Use Manage 2006;22(4):342-351. [doi: 10.1111/j.1475-2743.2006.00045.x].
    • (2006) Soil Use Manage , vol.22 , Issue.4 , pp. 342-351
    • Sleutel, S1    De Neve, S2    Beheydt, D3    Li, C4    Hofman, G.5
  • 21
    • 84983097000 scopus 로고    scopus 로고
    • Entropy based analysis of satellite magnetic data for searching possible electromagnetic signatures due to big earthquakes
    • [FREE Full text]
    • Cianchini G, De Santis A, Balasis G, Mandea M, Qamili E. Entropy based analysis of satellite magnetic data for searching possible electromagnetic signatures due to big earthquakes. Ma Comput Sci Eng 2009:29-35 [FREE Full text].
    • (2009) Ma Comput Sci Eng , pp. 29-35
    • Cianchini, G1    De Santis, A2    Balasis, G3    Mandea, M4    Qamili, E.5
  • 22
    • 84872310013 scopus 로고    scopus 로고
    • How President Obama's campaign used big data to rally indicidual voters
    • [FREE Full text]
    • Issenberg S. How President Obama's campaign used big data to rally indicidual voters. Technol Rev 2013;116(1):38-49 [FREE Full text].
    • (2013) Technol Rev , vol.116 , Issue.1 , pp. 38-49
    • Issenberg, S.1
  • 23
    • 0019429658 scopus 로고
    • Sex differences in psychiatric help-seeking: Evidence from four large-scale surveys
    • Mar; [Medline: 7240706]
    • Kessler RC, Brown RL, Broman CL. Sex differences in psychiatric help-seeking: Evidence from four large-scale surveys. J Health Soc Behav 1981 Mar;22(1):49-64. [Medline: 7240706].
    • (1981) J Health Soc Behav , vol.22 , Issue.1 , pp. 49-64
    • Kessler, RC1    Brown, RL2    Broman, CL.3
  • 24
    • 1542773568 scopus 로고    scopus 로고
    • Moneyball: The Art of Winning an Unfair Game: W
    • New York, New York: W. W. Norton & Company
    • Lewis M. Moneyball: The Art of Winning an Unfair Game: W. In: Moneyball: The Art of Winning an Unfair Game. New York, New York: W. W. Norton & Company; 2003.
    • (2003) Moneyball: The Art of Winning an Unfair Game
    • Lewis, M.1
  • 25
    • 77957676467 scopus 로고    scopus 로고
    • When pharmaceutical companies publish large datasets: An abundance of riches or fool's gold?
    • [doi] [Medline: 20732447]
    • Ekins S, Williams AJ. When pharmaceutical companies publish large datasets: An abundance of riches or fool's gold? Drug Discov Today 2010;15(19-20):812-815. [doi: 10.1016/j.drudis.2010.08.010] [Medline: 20732447].
    • (2010) Drug Discov Today , vol.15 , Issue.19-20 , pp. 812-815
    • Ekins, S1    Williams, AJ.2
  • 26
    • 0035820401 scopus 로고    scopus 로고
    • A new beginning for care for elderly people?
    • [FREE Full text] [Medline: 11290619]
    • Grimley Evans J, Tallis RC. A new beginning for care for elderly people? BMJ 2001;322(7290):807-808 [FREE Full text] [Medline: 11290619].
    • (2001) BMJ , vol.322 , Issue.7290 , pp. 807-808
    • Grimley Evans, J1    Tallis, RC.2
  • 27
    • 84880079763 scopus 로고    scopus 로고
    • Potentiality of big data in the medical sector: Focus on how to reshape the healthcare system
    • [FREE Full text] [doi] [Medline: 23882412]
    • Jee K, Kim GH. Potentiality of big data in the medical sector: Focus on how to reshape the healthcare system. Healthc Inform Res 2013;19(2):79-85 [FREE Full text] [doi: 10.4258/hir.2013.19.2.79] [Medline: 23882412].
    • (2013) Healthc Inform Res , vol.19 , Issue.2 , pp. 79-85
    • Jee, K1    Kim, GH.2
  • 28
    • 84875646817 scopus 로고    scopus 로고
    • The inevitable application of big data to health care
    • [doi] [Medline: 23549579]
    • Murdoch TB, Detsky AS. The inevitable application of big data to health care. JAMA 2013;309(13):1351-1352. [doi: 10.1001/jama.2013.393] [Medline: 23549579].
    • (2013) JAMA , vol.309 , Issue.13 , pp. 1351-1352
    • Murdoch, TB1    Detsky, AS.2
  • 29
    • 84856295588 scopus 로고    scopus 로고
    • The clinical value of large neuroimaging data sets in Alzheimer's disease
    • ix [FREE Full text] [doi] [Medline: 22284737]
    • Toga AW. The clinical value of large neuroimaging data sets in Alzheimer's disease. Neuroimaging Clin N Am 2012;22(1):107-118, ix [FREE Full text] [doi: 10.1016/j.nic.2011.11.008] [Medline: 22284737].
    • (2012) Neuroimaging Clin N Am , vol.22 , Issue.1 , pp. 107-118
    • Toga, AW.1
  • 30
    • 79953651813 scopus 로고    scopus 로고
    • Candidate genes for COPD in two large data sets
    • [FREE Full text] [doi] [Medline: 20562129]
    • Bakke PS, Zhu G, Gulsvik A, Kong X, Agusti AG, Calverley PM, et al. Candidate genes for COPD in two large data sets. Eur Respir J 2011;37(2):255-263 [FREE Full text] [doi: 10.1183/09031936.00091709] [Medline: 20562129].
    • (2011) Eur Respir J , vol.37 , Issue.2 , pp. 255-263
    • Bakke, PS1    Zhu, G2    Gulsvik, A3    Kong, X4    Agusti, AG5    Calverley, PM6
  • 31
    • 84878990796 scopus 로고    scopus 로고
    • Clinical genomic database
    • [FREE Full text] [doi] [Medline: 23696674]
    • Solomon BD, Nguyen AD, Bear KA, Wolfsberg TG. Clinical genomic database. Proc Natl Acad Sci USA 2013;110(24):9851-9855 [FREE Full text] [doi: 10.1073/pnas.1302575110] [Medline: 23696674].
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.24 , pp. 9851-9855
    • Solomon, BD1    Nguyen, AD2    Bear, KA3    Wolfsberg, TG.4
  • 32
    • 67649910087 scopus 로고    scopus 로고
    • Data warehousing for data mining based on Olap technology
    • 2008 Presented at: China-Ireland International Conference on Information and Communications Technologies; 26-28 Sept. Beijing, China [doi]
    • Liu XL, Du JP, Li WZ, Zuo M, Han ZM. Data warehousing for data mining based on Olap technology. In: Ciict 2008: Proceedings of China-Ireland International Conference on Information and Communications Technologies. 2008 Presented at: China-Ireland International Conference on Information and Communications Technologies; 26-28 Sept. 2008; Beijing, China p. 176-179. [doi: 10.1049/cp:20080786].
    • (2008) Ciict 2008: Proceedings of China-Ireland International Conference on Information and Communications Technologies , pp. 176-179
    • Liu, XL1    Du, JP2    Li, WZ3    Zuo, M4    Han, ZM.5
  • 33
    • 84863741148 scopus 로고    scopus 로고
    • The Age of Big DataURL: [WebCite Cache ID 6J7xJAwId]
    • Lohr S. The New York Times. 2012. The Age of Big DataURL: Http://www.nytimes.com/2012/02/12/sunday-review/big-datas-impact-in-the-world.html?pagewanted=1&-r=0[WebCite Cache ID 6J7xJAwId].
    • (2012) The New York Times
    • Lohr, S.1
  • 34
    • 85102593132 scopus 로고    scopus 로고
    • 2013URL: [accessed 2013-11-25] [WebCite Cache ID 6LOnNYQHV]
    • McCann E. EHR Boosts ROI. 2013URL: Http://www.healthcareitnews.com/news/ehr-boost-roi-revenue-medical-group [accessed 2013-11-25] [WebCite Cache ID 6LOnNYQHV].
    • EHR Boosts ROI
    • McCann, E.1
  • 35
    • 85102558416 scopus 로고    scopus 로고
    • group CIW. 2008URL: [accessed 2013-11-25] [WebCite Cache ID 6LOndM19u]
    • group CIW. EMR Benefits and Return on Investment Categories. 2008URL: Http://www.informatics-review.com/wiki/index.php/EMR-Benefits-and-Return-on-Investment-Categories [accessed 2013-11-25] [WebCite Cache ID 6LOndM19u].
    • EMR Benefits and Return on Investment Categories
  • 36
    • 0035808035 scopus 로고    scopus 로고
    • Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses
    • Dec 4; [Medline: 11730399]
    • Kjaergard LL, Villumsen J, Gluud C. Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses. Ann Intern Med 2001 Dec 4;135(11):982-989. [Medline: 11730399].
    • (2001) Ann Intern Med , vol.135 , Issue.11 , pp. 982-989
    • Kjaergard, LL1    Villumsen, J2    Gluud, C.3
  • 37
    • 0029005806 scopus 로고
    • Ambulatory blood pressure monitoring in the evaluation of antihypertensive treatment: Additional information from a large data base
    • [Medline: 7670648]
    • Mancia G, Omboni S, Ravogli A, Parati G, Zanchetti A. Ambulatory blood pressure monitoring in the evaluation of antihypertensive treatment: Additional information from a large data base. Blood Press 1995;4(3):148-156. [Medline: 7670648].
    • (1995) Blood Press , vol.4 , Issue.3 , pp. 148-156
    • Mancia, G1    Omboni, S2    Ravogli, A3    Parati, G4    Zanchetti, A.5
  • 38
    • 3142700228 scopus 로고    scopus 로고
    • BRCA1 testing with definitive results: A prospective study of psychological distress in a large clinic-based sample
    • [doi]
    • Reichelt JG, Heimdal K, Møller P, Dahl AA. BRCA1 testing with definitive results: A prospective study of psychological distress in a large clinic-based sample. Familial Cancer 2002;3(1):21-28. [doi: 10.1023/B:FAME.0000026820.32469.4a].
    • (2002) Familial Cancer , vol.3 , Issue.1 , pp. 21-28
    • Reichelt, JG1    Heimdal, K2    Møller, P3    Dahl, AA.4
  • 39
    • 58849114926 scopus 로고    scopus 로고
    • Characteristics of bipolar disorder in an Australian specialist outpatient clinic: Comparison across large datasets
    • [doi] [Medline: 19153918]
    • Mitchell PB, Johnston AK, Corry J, Ball JR, Malhi GS. Characteristics of bipolar disorder in an Australian specialist outpatient clinic: Comparison across large datasets. Aust N Z J Psychiatry 2009;43(2):109-117. [doi: 10.1080/00048670802607220] [Medline: 19153918].
    • (2009) Aust N Z J Psychiatry , vol.43 , Issue.2 , pp. 109-117
    • Mitchell, PB1    Johnston, AK2    Corry, J3    Ball, JR4    Malhi, GS.5
  • 41
    • 0025779484 scopus 로고
    • Atrial fibrillation as an independent risk factor for stroke: The Framingham Study
    • [FREE Full text] [Medline: 1866765]
    • Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: The Framingham Study. Stroke 1991;22(8):983-988 [FREE Full text] [Medline: 1866765].
    • (1991) Stroke , vol.22 , Issue.8 , pp. 983-988
    • Wolf, PA1    Abbott, RD2    Kannel, WB.3
  • 42
    • 0020533259 scopus 로고
    • Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study
    • [Medline: 6219830]
    • Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study. Circulation 1983;67(5):968-977. [Medline: 6219830].
    • (1983) Circulation , vol.67 , Issue.5 , pp. 968-977
    • Hubert, HB1    Feinleib, M2    McNamara, PM3    Castelli, WP.4
  • 43
    • 84867679582 scopus 로고    scopus 로고
    • Fitting parametric random effects models in very large data sets with application to VHA national data
    • [FREE Full text] [doi] [Medline: 23095325]
    • Gebregziabher M, Egede L, Gilbert GE, Hunt K, Nietert PJ, Mauldin P. Fitting parametric random effects models in very large data sets with application to VHA national data. BMC Med Res Methodol 2012;12:163 [FREE Full text] [doi: 10.1186/1471-2288-12-163] [Medline: 23095325].
    • (2012) BMC Med Res Methodol , vol.12 , pp. 163
    • Gebregziabher, M1    Egede, L2    Gilbert, GE3    Hunt, K4    Nietert, PJ5    Mauldin, P.6
  • 44
    • 80054863766 scopus 로고    scopus 로고
    • Amelia: A multi-center descriptive epidemiologic study in a large dataset from the International Clearinghouse for Birth Defects Surveillance and Research, and overview of the literature
    • [doi] [Medline: 22002956]
    • Bermejo-Sánchez E, Cuevas L, Amar E, Bakker MK, Bianca S, Bianchi F, et al. Amelia: A multi-center descriptive epidemiologic study in a large dataset from the International Clearinghouse for Birth Defects Surveillance and Research, and overview of the literature. Am J Med Genet C Semin Med Genet 2011;157C(4):288-304. [doi: 10.1002/ajmg.c.30319] [Medline: 22002956].
    • (2011) Am J Med Genet C Semin Med Genet , vol.157C , Issue.4 , pp. 288-304
    • Bermejo-Sánchez, E1    Cuevas, L2    Amar, E3    Bakker, MK4    Bianca, S5    Bianchi, F6
  • 45
    • 0036143447 scopus 로고    scopus 로고
    • Discriminant histological features in the diagnosis of chronic idiopathic inflammatory bowel disease: Analysis of a large dataset by a novel data visualisation technique
    • [FREE Full text] [Medline: 11825925]
    • Cross SS, Harrison RF. Discriminant histological features in the diagnosis of chronic idiopathic inflammatory bowel disease: Analysis of a large dataset by a novel data visualisation technique. J Clin Pathol 2002;55(1):51-57 [FREE Full text] [Medline: 11825925].
    • (2002) J Clin Pathol , vol.55 , Issue.1 , pp. 51-57
    • Cross, SS1    Harrison, RF.2
  • 46
    • 84876790290 scopus 로고    scopus 로고
    • Prevalence of clinical hip abnormalities in haemophilia A and B: An analysis of the UDC database
    • Joint Outcome Subcommittee of the Coordinating Committee for the Universal Data Collection Databasethe Hemophilia Treatment Center Network Investigators. [doi] [Medline: 23252621]
    • Kelly D, C Zhang Q, M Soucie J, Manco-Johnson M, Dimichele D, Joint Outcome Subcommittee of the Coordinating Committee for the Universal Data Collection Databasethe Hemophilia Treatment Center Network Investigators. Prevalence of clinical hip abnormalities in haemophilia A and B: An analysis of the UDC database. Haemophilia 2013;19(3):426-431. [doi: 10.1111/hae.12073] [Medline: 23252621].
    • (2013) Haemophilia , vol.19 , Issue.3 , pp. 426-431
    • Kelly, D1    C Zhang, Q2    Soucie, J3    Manco-Johnson, M4    Dimichele, D5
  • 47
    • 84873674422 scopus 로고    scopus 로고
    • Statistical methods to monitor risk factors in a clinical database: Example of a national cardiac surgery registry
    • [doi] [Medline: 23322806]
    • Siregar S, Roes KC, van Straten AH, Bots ML, van der Graaf Y, van Herwerden LA, et al. Statistical methods to monitor risk factors in a clinical database: Example of a national cardiac surgery registry. Circ Cardiovasc Qual Outcomes 2013;6(1):110-118. [doi: 10.1161/CIRCOUTCOMES.112.968800] [Medline: 23322806].
    • (2013) Circ Cardiovasc Qual Outcomes , vol.6 , Issue.1 , pp. 110-118
    • Siregar, S1    Roes, KC2    van Straten, AH3    Bots, ML4    van der Graaf, Y5    van Herwerden, LA6
  • 48
    • 84888211663 scopus 로고    scopus 로고
    • Non-high-density lipoprotein cholesterol, guideline targets, and population percentiles for secondary prevention in 1.3 million adults: The VLDL-2 Study (very large database of lipids)
    • Nov 19; [doi] [Medline: 23973689]
    • Elshazly MB, Martin SS, Blaha MJ, Joshi PH, Toth PP, McEvoy JW, et al. Non-high-density lipoprotein cholesterol, guideline targets, and population percentiles for secondary prevention in 1.3 million adults: The VLDL-2 Study (very large database of lipids). J Am Coll Cardiol 2013 Nov 19;62(21):1960-1965. [doi: 10.1016/j.jacc.2013.07.045] [Medline: 23973689].
    • (2013) J Am Coll Cardiol , vol.62 , Issue.21 , pp. 1960-1965
    • Elshazly, MB1    Martin, SS2    Blaha, MJ3    Joshi, PH4    Toth, PP5    McEvoy, JW6
  • 49
    • 84884461715 scopus 로고    scopus 로고
    • Using large datasets for population-based health research
    • Gallin JI, Ognibene FP. eds. 3rd ed. Maryland Heights, MO: Elsevier, Inc
    • Chan L, McGarey P. Using large datasets for population-based health research. In: Gallin JI, Ognibene FP. eds. Principles and Practice of Clinical Research. 3rd ed. Maryland Heights, MO: Elsevier, Inc; 2012:371-381.
    • (2012) Principles and Practice of Clinical Research , pp. 371-381
    • Chan, L1    McGarey, P.2
  • 50
    • 67650733181 scopus 로고    scopus 로고
    • Different properties of ACPA and IgM-RF derived from a large dataset: Further evidence of two distinct autoantibody systems
    • [FREE Full text] [doi] [Medline: 19460147]
    • Ursum J, Bos WH, van de Stadt RJ, Dijkmans BA, van Schaardenburg D. Different properties of ACPA and IgM-RF derived from a large dataset: Further evidence of two distinct autoantibody systems. Arthritis Res Ther 2009;11(3):R75 [FREE Full text] [doi: 10.1186/ar2704] [Medline: 19460147].
    • (2009) Arthritis Res Ther , vol.11 , Issue.3 , pp. R75
    • Ursum, J1    Bos, WH2    van de Stadt, RJ3    Dijkmans, BA4    van Schaardenburg, D.5
  • 51
    • 77955895769 scopus 로고    scopus 로고
    • Risk factors for stuttering: A secondary analysis of a large data base
    • [doi] [Medline: 19826856]
    • Ajdacic-Gross V, Vetter S, Müller M, Kawohl W, Frey F, Lupi G, et al. Risk factors for stuttering: A secondary analysis of a large data base. Eur Arch Psychiatry Clin Neurosci 2010;260(4):279-286. [doi: 10.1007/s00406-009-0075-4] [Medline: 19826856].
    • (2010) Eur Arch Psychiatry Clin Neurosci , vol.260 , Issue.4 , pp. 279-286
    • Ajdacic-Gross, V1    Vetter, S2    Müller, M3    Kawohl, W4    Frey, F5    Lupi, G6
  • 52
    • 70349221257 scopus 로고    scopus 로고
    • Quetiapine versus trazodone in reducing rehospitalization for alcohol dependence: A large data-base study
    • [doi] [Medline: 21768982]
    • Monnelly EP, Locastro JS, Gagnon D, Young M, Fiore LD. Quetiapine versus trazodone in reducing rehospitalization for alcohol dependence: A large data-base study. J Addict Med 2008;2(3):128-134. [doi: 10.1097/ADM.0b013e318165cb56] [Medline: 21768982].
    • (2008) J Addict Med , vol.2 , Issue.3 , pp. 128-134
    • Monnelly, EP1    Locastro, JS2    Gagnon, D3    Young, M4    Fiore, LD.5
  • 53
    • 38749108528 scopus 로고    scopus 로고
    • Sodium bicarbonate is associated with an increased incidence of contrast nephropathy: A retrospective cohort study of 7977 patients at mayo clinic
    • [FREE Full text] [doi] [Medline: 18057306]
    • From AM, Bartholmai BJ, Williams AW, Cha SS, Pflueger A, McDonald FS. Sodium bicarbonate is associated with an increased incidence of contrast nephropathy: A retrospective cohort study of 7977 patients at mayo clinic. Clin J Am Soc Nephrol 2008;3(1):10-18 [FREE Full text] [doi: 10.2215/CJN.03100707] [Medline: 18057306].
    • (2008) Clin J Am Soc Nephrol , vol.3 , Issue.1 , pp. 10-18
    • From, AM1    Bartholmai, BJ2    Williams, AW3    Cha, SS4    Pflueger, A5    McDonald, FS.6
  • 54
    • 33644877650 scopus 로고    scopus 로고
    • Accuracy of noninvasive ejection fraction measurement in a large community-based clinic
    • [FREE Full text] [Medline: 16012124]
    • Habash-Bseiso DE, Rokey R, Berger CJ, Weier AW, Chyou PH. Accuracy of noninvasive ejection fraction measurement in a large community-based clinic. Clin Med Res 2005;3(2):75-82 [FREE Full text] [Medline: 16012124].
    • (2005) Clin Med Res , vol.3 , Issue.2 , pp. 75-82
    • Habash-Bseiso, DE1    Rokey, R2    Berger, CJ3    Weier, AW4    Chyou, PH.5
  • 55
    • 79953792569 scopus 로고    scopus 로고
    • Uncovering the predictive value of minimum blood glucose through statistical analysis of a large clinical dataset
    • [FREE Full text] [Medline: 20351948]
    • Zhang Y, Hemond MS. Uncovering the predictive value of minimum blood glucose through statistical analysis of a large clinical dataset. AMIA Annu Symp Proc 2009;2009:725-729 [FREE Full text] [Medline: 20351948].
    • (2009) AMIA Annu Symp Proc , vol.2009 , pp. 725-729
    • Zhang, Y1    Hemond, MS.2
  • 56
    • 79952491611 scopus 로고    scopus 로고
    • Clinical effectiveness of biphasic insulin aspart 30:70 versus biphasic human insulin 30 in UK general clinical practice: A retrospective database study
    • [doi] [Medline: 21397771]
    • Morgan CL, Evans M, Toft AD, Jenkins-Jones S, Poole CD, Currie CJ. Clinical effectiveness of biphasic insulin aspart 30:70 versus biphasic human insulin 30 in UK general clinical practice: A retrospective database study. Clin Ther 2011;33(1):27-35. [doi: 10.1016/j.clinthera.2011.01.023] [Medline: 21397771].
    • (2011) Clin Ther , vol.33 , Issue.1 , pp. 27-35
    • Morgan, CL1    Evans, M2    Toft, AD3    Jenkins-Jones, S4    Poole, CD5    Currie, CJ.6
  • 57
    • 84902365884 scopus 로고    scopus 로고
    • Risk model for right hemicolectomy based on 19, 070 Japanese patients in the National Clinical Database
    • Jul 27. [doi] [Medline: 23892987]
    • Kobayashi H, Miyata H, Gotoh M, Baba H, Kimura W, Kitagawa Y, et al. Risk model for right hemicolectomy based on 19, 070 Japanese patients in the National Clinical Database. J Gastroenterol 2013 Jul 27. [doi: 10.1007/s00535-013-0860-8] [Medline: 23892987].
    • (2013) J Gastroenterol
    • Kobayashi, H1    Miyata, H2    Gotoh, M3    Baba, H4    Kimura, W5    Kitagawa, Y6
  • 58
    • 60849097257 scopus 로고    scopus 로고
    • Estimation of the warfarin dose with clinical and pharmacogenetic data
    • International Warfarin Pharmacogenetics Consortium, [FREE Full text] [doi] [Medline: 19228618]
    • International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, et al. Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med 2009;360(8):753-764 [FREE Full text] [doi: 10.1056/NEJMoa0809329] [Medline: 19228618].
    • (2009) N Engl J Med , vol.360 , Issue.8 , pp. 753-764
    • Klein, TE1    Altman, RB2    Eriksson, N3    Gage, BF4    Kimmel, SE5
  • 59
    • 84884675916 scopus 로고    scopus 로고
    • Using large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts
    • [FREE Full text] [doi] [Medline: 23044707]
    • Moreno-De-Luca D, Sanders SJ, Willsey AJ, Mulle JG, Lowe JK, Geschwind DH, et al. Using large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts. Mol Psychiatry 2013;18(10):1090-1095 [FREE Full text] [doi: 10.1038/mp.2012.138] [Medline: 23044707].
    • (2013) Mol Psychiatry , vol.18 , Issue.10 , pp. 1090-1095
    • Moreno-De-Luca, D1    Sanders, SJ2    Willsey, AJ3    Mulle, JG4    Lowe, JK5    Geschwind, DH6
  • 60
    • 80052284230 scopus 로고    scopus 로고
    • Combinations of SNPs related to signal transduction in bipolar disorder
    • [FREE Full text] [doi] [Medline: 21897858]
    • Koefoed P, Andreassen OA, Bennike B, Dam H, Djurovic S, Hansen T, et al. Combinations of SNPs related to signal transduction in bipolar disorder. PLoS One 2011;6(8):e23812 [FREE Full text] [doi: 10.1371/journal.pone.0023812] [Medline: 21897858].
    • (2011) PLoS One , vol.6 , Issue.8 , pp. e23812
    • Koefoed, P1    Andreassen, OA2    Bennike, B3    Dam, H4    Djurovic, S5    Hansen, T6
  • 61
    • 84893534021 scopus 로고    scopus 로고
    • Exploring the use of large clinical data to inform patients for shared decision making
    • [Medline: 23920678]
    • Hill B, Proulx J, Zeng-Treitler Q. Exploring the use of large clinical data to inform patients for shared decision making. Stud Health Technol Inform 2013;192:851-855. [Medline: 23920678].
    • (2013) Stud Health Technol Inform , vol.192 , pp. 851-855
    • Hill, B1    Proulx, J2    Zeng-Treitler, Q.3
  • 62
    • 55349095801 scopus 로고    scopus 로고
    • Evaluation of computer-aided diagnosis on a large clinical full-field digital mammographic dataset
    • [FREE Full text] [doi] [Medline: 18995194]
    • Li H, Giger ML, Yuan Y, Chen W, Horsch K, Lan L, et al. Evaluation of computer-aided diagnosis on a large clinical full-field digital mammographic dataset. Acad Radiol 2008;15(11):1437-1445 [FREE Full text] [doi: 10.1016/j.acra.2008.05.004] [Medline: 18995194].
    • (2008) Acad Radiol , vol.15 , Issue.11 , pp. 1437-1445
    • Li, H1    Giger, ML2    Yuan, Y3    Chen, W4    Horsch, K5    Lan, L6
  • 63
    • 84870063227 scopus 로고    scopus 로고
    • Computerized analysis of mammographic parenchymal patterns on a large clinical dataset of full-field digital mammograms: Robustness study with two high-risk datasets
    • [FREE Full text] [doi] [Medline: 22246204]
    • Li H, Giger ML, Lan L, Bancroft Brown J, MacMahon A, Mussman M, et al. Computerized analysis of mammographic parenchymal patterns on a large clinical dataset of full-field digital mammograms: Robustness study with two high-risk datasets. J Digit Imaging 2012;25(5):591-598 [FREE Full text] [doi: 10.1007/s10278-012-9452-z] [Medline: 22246204].
    • (2012) J Digit Imaging , vol.25 , Issue.5 , pp. 591-598
    • Li, H1    Giger, ML2    Lan, L3    Bancroft Brown, J4    MacMahon, A5    Mussman, M6
  • 64
    • 84884217961 scopus 로고    scopus 로고
    • Feasibility of using Clinical Element Models (CEM) to standardize phenotype variables in the database of genotypes and phenotypes (dbGaP)
    • [FREE Full text] [doi] [Medline: 24058713]
    • Lin KW, Tharp M, Conway M, Hsieh A, Ross M, Kim J, et al. Feasibility of using Clinical Element Models (CEM) to standardize phenotype variables in the database of genotypes and phenotypes (dbGaP). PLoS One 2013;8(9):e76384 [FREE Full text] [doi: 10.1371/journal.pone.0076384] [Medline: 24058713].
    • (2013) PLoS One , vol.8 , Issue.9 , pp. e76384
    • Lin, KW1    Tharp, M2    Conway, M3    Hsieh, A4    Ross, M5    Kim, J6
  • 65
    • 16544388924 scopus 로고    scopus 로고
    • Feasibility of using a large Clinical Data Warehouse to automate the selection of diagnostic cohorts
    • [FREE Full text] [Medline: 14728522]
    • Stephen R, Boxwala A, Gertman P. Feasibility of using a large Clinical Data Warehouse to automate the selection of diagnostic cohorts. AMIA Annu Symp Proc 2003:1019 [FREE Full text] [Medline: 14728522].
    • (2003) AMIA Annu Symp Proc , pp. 1019
    • Stephen, R1    Boxwala, A2    Gertman, P.3
  • 66
    • 84883140233 scopus 로고    scopus 로고
    • Benefits of a clinical data warehouse with data mining tools to collect data for a radiotherapy trial
    • [doi] [Medline: 23394741]
    • Roelofs E, Persoon L, Nijsten S, Wiessler W, Dekker A, Lambin P. Benefits of a clinical data warehouse with data mining tools to collect data for a radiotherapy trial. Radiother Oncol 2013;108(1):174-179. [doi: 10.1016/j.radonc.2012.09.019] [Medline: 23394741].
    • (2013) Radiother Oncol , vol.108 , Issue.1 , pp. 174-179
    • Roelofs, E1    Persoon, L2    Nijsten, S3    Wiessler, W4    Dekker, A5    Lambin, P.6
  • 67
    • 84891837451 scopus 로고    scopus 로고
    • The Human Gene Mutation Database: Building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine
    • Sep 28. [doi] [Medline: 24077912]
    • Stenson PD, Mort M, Ball EV, Shaw K, Phillips AD, Cooper DN. The Human Gene Mutation Database: Building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine. Hum Genet 2013 Sep 28. [doi: 10.1007/s00439-013-1358-4] [Medline: 24077912].
    • (2013) Hum Genet
    • Stenson, PD1    Mort, M2    Ball, EV3    Shaw, K4    Phillips, AD5    Cooper, DN.6
  • 68
    • 6344278614 scopus 로고    scopus 로고
    • Biomedical informatics: Development of a comprehensive data warehouse for clinical and genomic breast cancer research
    • [doi] [Medline: 15469411]
    • Hu H, Brzeski H, Hutchins J, Ramaraj M, Qu L, Xiong R, et al. Biomedical informatics: Development of a comprehensive data warehouse for clinical and genomic breast cancer research. Pharmacogenomics 2004;5(7):933-941. [doi: 10.1517/14622416.5.7.933] [Medline: 15469411].
    • (2004) Pharmacogenomics , vol.5 , Issue.7 , pp. 933-941
    • Hu, H1    Brzeski, H2    Hutchins, J3    Ramaraj, M4    Qu, L5    Xiong, R6
  • 69
    • 84856488426 scopus 로고    scopus 로고
    • A curated database of genetic markers from the angiogenesis/VEGF pathway and their relation to clinical outcome in human cancers
    • [doi] [Medline: 22150118]
    • Savas S. A curated database of genetic markers from the angiogenesis/VEGF pathway and their relation to clinical outcome in human cancers. Acta Oncol 2012;51(2):243-246. [doi: 10.3109/0284186X.2011.636758] [Medline: 22150118].
    • (2012) Acta Oncol , vol.51 , Issue.2 , pp. 243-246
    • Savas, S.1
  • 70
    • 84862210985 scopus 로고    scopus 로고
    • CDKD: A clinical database of kidney diseases
    • [FREE Full text] [doi] [Medline: 22540288]
    • Singh SK, Malik A, Firoz A, Jha V. CDKD: A clinical database of kidney diseases. BMC Nephrol 2012;13:23 [FREE Full text] [doi: 10.1186/1471-2369-13-23] [Medline: 22540288].
    • (2012) BMC Nephrol , vol.13 , pp. 23
    • Singh, SK1    Malik, A2    Firoz, A3    Jha, V.4
  • 71
    • 78650193866 scopus 로고    scopus 로고
    • Nationwide survey and establishment of a clinical database for gastrointestinal surgery in Japan: Targeting integration of a cancer registration system and improving the outcome of cancer treatment
    • [doi] [Medline: 20961361]
    • Suzuki H, Gotoh M, Sugihara K, Kitagawa Y, Kimura W, Kondo S, et al. Nationwide survey and establishment of a clinical database for gastrointestinal surgery in Japan: Targeting integration of a cancer registration system and improving the outcome of cancer treatment. Cancer Sci 2011;102(1):226-230. [doi: 10.1111/j.1349-7006.2010.01749.x] [Medline: 20961361].
    • (2011) Cancer Sci , vol.102 , Issue.1 , pp. 226-230
    • Suzuki, H1    Gotoh, M2    Sugihara, K3    Kitagawa, Y4    Kimura, W5    Kondo, S6
  • 72
    • 84892160333 scopus 로고    scopus 로고
    • Bringing big data to personalized healthcare: A patient-centered framework
    • (suppl 3): [doi] [Medline: 23797912]
    • Chawla NV, Davis DA. Bringing big data to personalized healthcare: A patient-centered framework. J Gen Intern Med 2013;28(suppl 3):S660-S665. [doi: 10.1007/s11606-013-2455-8] [Medline: 23797912].
    • (2013) J Gen Intern Med , vol.28 , pp. S660-S665
    • Chawla, NV1    Davis, DA.2
  • 73
    • 78649517091 scopus 로고    scopus 로고
    • Citizen Centric Architecture approach-taking e-health forward by integrating citizens and service providers
    • (Pt 2): [Medline: 20841816]
    • Han Y, Itälä T, Hämälaïnen M. Citizen Centric Architecture approach-taking e-health forward by integrating citizens and service providers. Stud Health Technol Inform 2010;160(Pt 2):907-911. [Medline: 20841816].
    • (2010) Stud Health Technol Inform , vol.160 , pp. 907-911
    • Han, Y1    Itälä, T2    Hämälaïnen, M.3
  • 74
    • 84872237224 scopus 로고    scopus 로고
    • A clinical data warehouse-based process for refining medication orders alerts
    • [FREE Full text] [doi] [Medline: 22523345]
    • Boussadi A, Caruba T, Zapletal E, Sabatier B, Durieux P, Degoulet P. A clinical data warehouse-based process for refining medication orders alerts. J Am Med Inform Assoc 2012;19(5):782-785 [FREE Full text] [doi: 10.1136/amiajnl-2012-000850] [Medline: 22523345].
    • (2012) J Am Med Inform Assoc , vol.19 , Issue.5 , pp. 782-785
    • Boussadi, A1    Caruba, T2    Zapletal, E3    Sabatier, B4    Durieux, P5    Degoulet, P.6
  • 77
    • 77951641206 scopus 로고    scopus 로고
    • Development of traditional Chinese medicine clinical data warehouse for medical knowledge discovery and decision support
    • [doi] [Medline: 20122820]
    • Zhou X, Chen S, Liu B, Zhang R, Wang Y, Li P, et al. Development of traditional Chinese medicine clinical data warehouse for medical knowledge discovery and decision support. Artif Intell Med 2010;48(2-3):139-152. [doi: 10.1016/j.artmed.2009.07.012] [Medline: 20122820].
    • (2010) Artif Intell Med , vol.48 , Issue.2-3 , pp. 139-152
    • Zhou, X1    Chen, S2    Liu, B3    Zhang, R4    Wang, Y5    Li, P6
  • 78
    • 78649493608 scopus 로고    scopus 로고
    • Methodology of integration of a clinical data warehouse with a clinical information system: The HEGP case
    • (Pt 1): [Medline: 20841676]
    • Zapletal E, Rodon N, Grabar N, Degoulet P. Methodology of integration of a clinical data warehouse with a clinical information system: The HEGP case. Stud Health Technol Inform 2010;160(Pt 1):193-197. [Medline: 20841676].
    • (2010) Stud Health Technol Inform , vol.160 , pp. 193-197
    • Zapletal, E1    Rodon, N2    Grabar, N3    Degoulet, P.4
  • 79
    • 76649094610 scopus 로고    scopus 로고
    • Integration of decentralized clinical data in a data warehouse: A service-oriented design and realization
    • [doi] [Medline: 19657544]
    • Hanss S, Schaaf T, Wetzel T, Hahn C, Schrader T, Tolxdorff T. Integration of decentralized clinical data in a data warehouse: A service-oriented design and realization. Methods Inf Med 2009;48(5):414-418. [doi: 10.3414/ME9240] [Medline: 19657544].
    • (2009) Methods Inf Med , vol.48 , Issue.5 , pp. 414-418
    • Hanss, S1    Schaaf, T2    Wetzel, T3    Hahn, C4    Schrader, T5    Tolxdorff, T.6
  • 81
    • 37849046438 scopus 로고    scopus 로고
    • Introduction to the mining of clinical data
    • [doi] [Medline: 18194715]
    • Harrison JH. Introduction to the mining of clinical data. Clin Lab Med 2008;28(1):1-7. [doi: 10.1016/j.cll.2007.10.001] [Medline: 18194715].
    • (2008) Clin Lab Med , vol.28 , Issue.1 , pp. 1-7
    • Harrison, JH.1
  • 82
    • 84871015639 scopus 로고    scopus 로고
    • Multiscale integration of-omic, imaging, and clinical data in biomedical informatics
    • [doi] [Medline: 23231990]
    • Phan JH, Quo CF, Cheng C, Wang MD. Multiscale integration of-omic, imaging, and clinical data in biomedical informatics. IEEE Rev Biomed Eng 2012;5:74-87. [doi: 10.1109/RBME.2012.2212427] [Medline: 23231990].
    • (2012) IEEE Rev Biomed Eng , vol.5 , pp. 74-87
    • Phan, JH1    Quo, CF2    Cheng, C3    Wang, MD.4
  • 83
    • 70350465146 scopus 로고    scopus 로고
    • Large datasets in biomedicine: A discussion of salient analytic issues
    • [FREE Full text] [doi] [Medline: 19717808]
    • Sinha A, Hripcsak G, Markatou M. Large datasets in biomedicine: A discussion of salient analytic issues. J Am Med Inform Assoc 2009;16(6):759-767 [FREE Full text] [doi: 10.1197/jamia.M2780] [Medline: 19717808].
    • (2009) J Am Med Inform Assoc , vol.16 , Issue.6 , pp. 759-767
    • Sinha, A1    Hripcsak, G2    Markatou, M.3
  • 84
    • 32344442418 scopus 로고    scopus 로고
    • A new empirical angle on the variability debate: Quantitative neurosyntactic analyses of a large data set from Broca's aphasia
    • [doi] [Medline: 16115671]
    • Drai D, Grodzinsky Y. A new empirical angle on the variability debate: Quantitative neurosyntactic analyses of a large data set from Broca's aphasia. Brain Lang 2006;96(2):117-128. [doi: 10.1016/j.bandl.2004.10.016] [Medline: 16115671].
    • (2006) Brain Lang , vol.96 , Issue.2 , pp. 117-128
    • Drai, D1    Grodzinsky, Y.2
  • 85
    • 4143108613 scopus 로고
    • DYNAMIC PROGRAMMING AND STATISTICAL COMMUNICATION THEORY
    • [FREE Full text] [Medline: 16590080]
    • Bellman R, Kalaba R. DYNAMIC PROGRAMMING AND STATISTICAL COMMUNICATION THEORY. Proc Natl Acad Sci USA 1957;43(8):749-751 [FREE Full text] [Medline: 16590080].
    • (1957) Proc Natl Acad Sci USA , vol.43 , Issue.8 , pp. 749-751
    • Bellman, R1    Kalaba, R.2
  • 88
    • 85102574176 scopus 로고    scopus 로고
    • 2007URL: [accessed 2013-11-25] [WebCite Cache ID 6LOp7PTH6]
    • Litt S. NoSQL: The Unix Database (With awk). 2007URL: Http://www.troubleshooters.com/lpm/200704/200704.htm [accessed 2013-11-25] [WebCite Cache ID 6LOp7PTH6].
    • NoSQL: The Unix Database (With awk)
    • Litt, S.1
  • 89
    • 33845951476 scopus 로고    scopus 로고
    • Parallel processing of large datasets from NanoLC-FTICR-MS measurements
    • [doi] [Medline: 17055738]
    • van der Burgt YE, Taban IM, Konijnenburg M, Biskup M, Duursma MC, Heeren RM, et al. Parallel processing of large datasets from NanoLC-FTICR-MS measurements. J Am Soc Mass Spectrom 2007;18(1):152-161. [doi: 10.1016/j.jasms.2006.09.005] [Medline: 17055738].
    • (2007) J Am Soc Mass Spectrom , vol.18 , Issue.1 , pp. 152-161
    • van der Burgt, YE1    Taban, IM2    Konijnenburg, M3    Biskup, M4    Duursma, MC5    Heeren, RM6
  • 90
    • 85102593974 scopus 로고    scopus 로고
    • Stata reference manual : Release 6
    • Stata Corporation College Station, TX: Stata Corp
    • Stata Corporation. Stata reference manual : Release 6. In: Stata Reference Manual Set, 4vol: Release 6. College Station, TX: Stata Corp; 1999.
    • (1999) Stata Reference Manual Set, 4vol: Release 6
  • 91
    • 85102579104 scopus 로고    scopus 로고
    • R Development Core Team. official website for R. Vienna, Austria The R Project for Statistical ComputingURL: [accessed 2014-01-08] [WebCite Cache ID 6MU3hBSqT]
    • R Development Core Team. official website for R. Vienna, Austria The R Project for Statistical ComputingURL: Http://www.r-project.org/[accessed 2014-01-08] [WebCite Cache ID 6MU3hBSqT].
  • 92
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • [FREE Full text] [Medline: 12538238]
    • Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 2003;19(2):185-193 [FREE Full text] [Medline: 12538238].
    • (2003) Bioinformatics , vol.19 , Issue.2 , pp. 185-193
    • Bolstad, BM1    Irizarry, RA2    Astrand, M3    Speed, TP.4
  • 93
    • 79959573076 scopus 로고    scopus 로고
    • Heat map visualization of complex environmental and biomarker measurements
    • [doi] [Medline: 21492901]
    • Pleil JD, Stiegel MA, Madden MC, Sobus JR. Heat map visualization of complex environmental and biomarker measurements. Chemosphere 2011;84(5):716-723. [doi: 10.1016/j.chemosphere.2011.03.017] [Medline: 21492901].
    • (2011) Chemosphere , vol.84 , Issue.5 , pp. 716-723
    • Pleil, JD1    Stiegel, MA2    Madden, MC3    Sobus, JR.4
  • 94
    • 84859905115 scopus 로고    scopus 로고
    • Alignment of multiple complete genomes suggests that gene rearrangements may contribute towards the speciation of Mycobacteria
    • [doi] [Medline: 22008279]
    • Garcia-Betancur JC, Menendez MC, Del Portillo P, Garcia MJ. Alignment of multiple complete genomes suggests that gene rearrangements may contribute towards the speciation of Mycobacteria. Infect Genet Evol 2012;12(4):819-826. [doi: 10.1016/j.meegid.2011.09.024] [Medline: 22008279].
    • (2012) Infect Genet Evol , vol.12 , Issue.4 , pp. 819-826
    • Garcia-Betancur, JC1    Menendez, MC2    Del Portillo, P3    Garcia, MJ.4
  • 95
    • 80052782415 scopus 로고    scopus 로고
    • A visualization of 3D proteome universe: Mapping of a proteome ensemble into 3D space based on the protein-structure composition
    • [doi] [Medline: 21762784]
    • Aita T, Nishigaki K. A visualization of 3D proteome universe: Mapping of a proteome ensemble into 3D space based on the protein-structure composition. Mol Phylogenet Evol 2011;61(2):484-494. [doi: 10.1016/j.ympev.2011.06.020] [Medline: 21762784].
    • (2011) Mol Phylogenet Evol , vol.61 , Issue.2 , pp. 484-494
    • Aita, T1    Nishigaki, K.2
  • 98
    • 0036937227 scopus 로고    scopus 로고
    • Data integration through database federation
    • [doi]
    • Haas LM, Lin ET, Roth MA. Data integration through database federation. IBM Syst. J 2002;41(4):578-596. [doi: 10.1147/sj.414.0578].
    • (2002) IBM Syst. J , vol.41 , Issue.4 , pp. 578-596
    • Haas, LM1    Lin, ET2    Roth, MA.3
  • 99
    • 70349466388 scopus 로고    scopus 로고
    • Reducing the bias and uncertainty of free energy estimates by using regression to fit thermodynamic integration data
    • [doi] [Medline: 19266482]
    • Shyu C, Ytreberg FM. Reducing the bias and uncertainty of free energy estimates by using regression to fit thermodynamic integration data. J Comput Chem 2009;30(14):2297-2304. [doi: 10.1002/jcc.21231] [Medline: 19266482].
    • (2009) J Comput Chem , vol.30 , Issue.14 , pp. 2297-2304
    • Shyu, C1    Ytreberg, FM.2
  • 100
    • 33746951437 scopus 로고    scopus 로고
    • Classification criteria for psoriatic arthritis: Development of new criteria from a large international study
    • CASPAR Study Group. [FREE Full text] [doi] [Medline: 16871531]
    • Taylor W, Gladman D, Helliwell P, Marchesoni A, Mease P, Mielants H, CASPAR Study Group. Classification criteria for psoriatic arthritis: Development of new criteria from a large international study. Arthritis Rheum 2006;54(8):2665-2673 [FREE Full text] [doi: 10.1002/art.21972] [Medline: 16871531].
    • (2006) Arthritis Rheum , vol.54 , Issue.8 , pp. 2665-2673
    • Taylor, W1    Gladman, D2    Helliwell, P3    Marchesoni, A4    Mease, P5    Mielants, H6
  • 101
    • 0023239550 scopus 로고    scopus 로고
    • Analyse der zeitlichen Veränderungen der Papillen-Reflexion mittels Hauptkomponentenanalyse
    • (04):. [doi]
    • Gschwind R, Robert Y. Analyse der zeitlichen Veränderungen der Papillen-Reflexion mittels Hauptkomponentenanalyse. Klin Monatsbl Augenheilkd 2008;190(04):249. [doi: 10.1055/s-2008-1050370].
    • (2008) Klin Monatsbl Augenheilkd , vol.190 , pp. 249
    • Gschwind, R1    Robert, Y.2
  • 102
    • 33749410653 scopus 로고    scopus 로고
    • Bayesian model averaging of naive Bayes for clustering
    • [Medline: 17036820]
    • Santafé G, Lozano JA, Larranãga P. Bayesian model averaging of naive Bayes for clustering. IEEE Trans Syst Man Cybern B Cybern 2006;36(5):1149-1161. [Medline: 17036820].
    • (2006) IEEE Trans Syst Man Cybern B Cybern , vol.36 , Issue.5 , pp. 1149-1161
    • Santafé, G1    Lozano, JA2    Larranãga, P.3
  • 103
    • 0034597564 scopus 로고    scopus 로고
    • Therapeutic decision tree for patients with sustained ventricular tachyarrhythmias or aborted cardiac arrest: A critical review of the Antiarrhythmics Versus Implantable Defibrillator trial and the Canadian Implantable Defibrillator Study
    • [Medline: 11084100]
    • Farré J, Cabrera JA, Romero J, Rubio JM. Therapeutic decision tree for patients with sustained ventricular tachyarrhythmias or aborted cardiac arrest: A critical review of the Antiarrhythmics Versus Implantable Defibrillator trial and the Canadian Implantable Defibrillator Study. Am J Cardiol 2000;86(9A):44K-51K. [Medline: 11084100].
    • (2000) Am J Cardiol , vol.86 , Issue.9A , pp. 44K-51K
    • Farré, J1    Cabrera, JA2    Romero, J3    Rubio, JM.4
  • 104
    • 0036127092 scopus 로고    scopus 로고
    • A review of evidence of health benefit from artificial neural networks in medical intervention
    • [Medline: 11958484]
    • Lisboa PJ. A review of evidence of health benefit from artificial neural networks in medical intervention. Neural Netw 2002;15(1):11-39. [Medline: 11958484].
    • (2002) Neural Netw , vol.15 , Issue.1 , pp. 11-39
    • Lisboa, PJ.1
  • 105
    • 67651249916 scopus 로고    scopus 로고
    • In silico log P prediction for a large data set with support vector machines, radial basis neural networks and multiple linear regression
    • [doi] [Medline: 19549084]
    • Chen HF. In silico log P prediction for a large data set with support vector machines, radial basis neural networks and multiple linear regression. Chem Biol Drug Des 2009;74(2):142-147. [doi: 10.1111/j.1747-0285.2009.00840.x] [Medline: 19549084].
    • (2009) Chem Biol Drug Des , vol.74 , Issue.2 , pp. 142-147
    • Chen, HF.1
  • 106
    • 0029966556 scopus 로고    scopus 로고
    • Adjusting for multiple testing when reporting research results: The Bonferroni vs Holm methods
    • [doi]
    • Aickin M, Gensler H. Adjusting for multiple testing when reporting research results: The Bonferroni vs Holm methods. Am J Public Health 1996;86(5):726-728. [doi: 10.2105/Ajph.86.5.726].
    • (1996) Am J Public Health , vol.86 , Issue.5 , pp. 726-728
    • Aickin, M1    Gensler, H.2
  • 107
    • 0035049158 scopus 로고    scopus 로고
    • Adjusting for multiple testing-when and how?
    • [doi]
    • Bender R, Lange S. Adjusting for multiple testing-when and how? Journal of Clinical Epidemiology 2001;54(4):343-349. [doi: 10.1016/S0895-4356(00)00314-0].
    • (2001) Journal of Clinical Epidemiology , vol.54 , Issue.4 , pp. 343-349
    • Bender, R1    Lange, S.2
  • 108
    • 25444452877 scopus 로고    scopus 로고
    • A comparative review of estimates of the proportion unchanged genes and the false discovery rate
    • [FREE Full text] [doi] [Medline: 16086831]
    • Broberg P. A comparative review of estimates of the proportion unchanged genes and the false discovery rate. BMC Bioinformatics 2005;6:199 [FREE Full text] [doi: 10.1186/1471-2105-6-199] [Medline: 16086831].
    • (2005) BMC Bioinformatics , vol.6 , pp. 199
    • Broberg, P.1
  • 109
    • 14644392927 scopus 로고    scopus 로고
    • Multiple testing. Part II. Step-down procedures for control of the family-wise error rate
    • [doi]
    • van der Laan MJ, Dudoit S, Pollard KS. Multiple testing. Part II. Step-down procedures for control of the family-wise error rate. Stat Appl Genet Mol Biol 2004;3. [doi: 10.2202/1544-6115.1041].
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • van der Laan, MJ1    Dudoit, S2    Pollard, KS.3
  • 110
  • 112
    • 84877790012 scopus 로고    scopus 로고
    • Differences in clinical manifestations, treatment, and concordance rates with two major sets of criteria for Behçet's syndrome for patients in the US and Japan: Data from a large, three-center cohort study
    • [doi] [Medline: 22752504]
    • Kobayashi T, Kishimoto M, Swearingen CJ, Filopoulos MT, Ohara Y, Tokuda Y, et al. Differences in clinical manifestations, treatment, and concordance rates with two major sets of criteria for Behçet's syndrome for patients in the US and Japan: Data from a large, three-center cohort study. Mod Rheumatol 2013;23(3):547-553. [doi: 10.1007/s10165-012-0696-8] [Medline: 22752504].
    • (2013) Mod Rheumatol , vol.23 , Issue.3 , pp. 547-553
    • Kobayashi, T1    Kishimoto, M2    Swearingen, CJ3    Filopoulos, MT4    Ohara, Y5    Tokuda, Y6
  • 113
    • 69149090568 scopus 로고    scopus 로고
    • The pathologies of big data
    • [doi]
    • Jacobs A. The pathologies of big data. Commun ACM 2009;52(8):36. [doi: 10.1145/1536616.1536632].
    • (2009) Commun ACM , vol.52 , Issue.8 , pp. 36
    • Jacobs, A.1


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