Biosynthesis of medicinal tropane alkaloids in yeast

Nature

Volumn 585, Issue 7826, 2020, Pages 614-619

  Srinivasan, Prashanth ^a   Smolke, Christina D ^a,b  

^a Stanford University   (United States)

^b CHAN ZUCKERBERG BIOHUB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; AMINO ACID; ANIMAL PROTEIN; BACTERIAL PROTEIN; CARBOHYDRATE; FUNGAL PROTEIN; HYOSCYAMINE; HYOSCYAMINE DEHYDROGENASE; LITTORINE; OXIDOREDUCTASE; PLANT PROTEIN; SCOPOLAMINE; TROPANE ALKALOID; UNCLASSIFIED DRUG; 3-PHENYLLACTIC ACID; ALKALOID; ATROPINE DERIVATIVE; GLUCOSIDE; LACTIC ACID; LIGASE;

ALKALOID; AMINO ACID; BACTERIUM; CELL; ENVIRONMENTAL FACTOR; GENE EXPRESSION; GENETIC ENGINEERING; MICROBIAL ACTIVITY; NERVOUS SYSTEM DISORDER; PROTEIN; SUGAR; YEAST;

ARTICLE; BIOENGINEERING; CELL TRANSPORT; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG SYNTHESIS; FUNCTIONAL GENOMICS; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; ANIMAL; ATROPA BELLADONNA; BIOSYNTHESIS; DATURA; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR MODEL; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA; SOLANUM;

ACYLTRANSFERASES; ALKALOIDS; ANIMALS; ATROPA BELLADONNA; ATROPINE DERIVATIVES; BIOLOGICAL TRANSPORT; DATURA; GLUCOSIDES; HYOSCYAMINE; LACTATES; LIGASES; MODELS, MOLECULAR; NERVOUS SYSTEM DISEASES; OXIDOREDUCTASES; PROTEIN ENGINEERING; SACCHAROMYCES CEREVISIAE; SCOPOLAMINE; VACUOLES;

EID: 85090193439     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/s41586-020-2650-9     Document Type: Article

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