Use of the informational spectrum methodology for rapid biological analysis of the novel coronavirus 2019-nCoV: Prediction of potential receptor, natural reservoir, tropism and therapeutic/vaccine target

F1000Research

Volumn 9, Issue , 2020, Pages

  Veljkovic, Veljko ^a   Vergara Alert, Júlia ^b   Segalés, Joaquim ^c   Paessler, Slobodan ^d  

^a Biomed Protection   (United States)

^b IRTA   (Spain)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d University of Texas Medical Branch School of Medicine   (United States)

Author keywords

2019 nCoV; MERS; SARS; Wuhan coronavirus

Indexed keywords

VIRUS RECEPTOR; COVID-19 VACCINE; VIRUS VACCINE;

AMINO ACID SEQUENCE; ARTICLE; COMPUTER MODEL; CORONAVIRUS DISEASE 2019; DRUG TARGETING; MOLECULAR PHYLOGENY; NONHUMAN; PHYLOGENETIC TREE; PREDICTION; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VIRAL TROPISM; VIRUS CARRIER; BETACORONAVIRUS; CORONAVIRUS INFECTION; HUMAN; IMMUNOLOGY; PANDEMIC; TROPISM; VIRUS PNEUMONIA;

BETACORONAVIRUS; CORONAVIRUS INFECTIONS; HUMANS; PANDEMICS; PNEUMONIA, VIRAL; TROPISM; VIRAL VACCINES;

EID: 85082199910     PISSN: 20461402     EISSN: 1759796X     Source Type: Journal    
DOI: 10.12688/f1000research.22149.3     Document Type: Article

References (21)

1. Veljković V Cosić I Dimitrijević B: Is it possible to analyze DNA and protein sequences by the methods of digital signal processing? IEEE Trans Biomed Eng. 1985;32(5):337-41. 2581884 10.1109/TBME.1985.325549
2. Veljkovic V Niman HL Glisic S: Identification of hemagglutinin structural domain and polymorphisms which may modulate swine H1N1 interactions with human receptor. BMC Struct Biol. 2009;9:62. 19785758 10.1186/1472-6807-9-62 2760557
3. Veljkovic V Glisic S Muller CP: In silico analysis suggests interaction between Ebola virus and the extracellular matrix. Front Microbiol. 2015;6:135. 25745423 10.3389/fmicb.2015.00135 4333865
4. Paessler S Veljkovic V: Prediction of influenza vaccine effectiveness for the influenza season 2017/18 in the US [version 1; peer review: 2 approved]. F1000Res. 2017;6:2067. 29535862 10.12688/f1000research.13198.1 5795273
5. Koma T Veljkovic V Anderson DE: Zika virus infection elicits auto-antibodies to C1q. Sci Rep. 2018;8(1):1882. 29382894 10.1038/s41598-018-20185-8 5789871
6. Veljković V Slavić I: Simple general-model pseudopotential. Phys Rev Let. 1972;29:105. 10.1103/PhysRevLett.29.105
7. Perovic VR Muller CP Niman HL: Novel phylogenetic algorithm to monitor human tropism in Egyptian H5N1-HPAIV reveals evolution toward efficient human-to-human transmission. PLoS One. 2013;8(4):e61572. 23658611 10.1371/journal.pone.0061572 3637272
8. Schmier S Mostafa A Haarmann T: In Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses. Sci Rep. 2015;5:11434. 26091504 10.1038/srep11434 4473683
9. Li W Moore MJ Vasilieva N: Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003;426(6965):450-4. 14647384 10.1038/nature02145
10. Raj VS Mou H Smits SL: Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature. 2013;495(7440):251-4. 23486063 10.1038/nature12005
11. Müller MA Raj VS Muth D: Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines. mBio. 2012;3(6): pii: e00515-12. 23232719 10.1128/mBio.00515-12 3520110
12. Letko M Marzi A Munster V: Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol. 2020;5(4):562-569. 32094589 10.1038/s41564-020-0688-y
13. Shi J Wen Z Zhong G: Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2. Science. 2020; pii: eabb7015. 32269068 10.1126/science.abb7015 7164390
14. Owczarek K Szczepanski A Milewska A: Early events during human coronavirus OC43 entry to the cell. Sci Rep. 2018;8(1):7124. 29740099 10.1038/s41598-018-25640-0 5940804
15. Doceul V Hollinshead M van der Linden L: Repulsion of superinfecting virions: a mechanism for rapid virus spread. Science. 2010;327(5967):873-876. 20093437 10.1126/science.1183173 4202693
16. Du L Zhou J Zhang J: Actin filament reorganization is a key step in lung inflammation induced by systemic inflammatory response syndrome. Am J Respir Cell Mol Biol. 2012;47(5):597-603. 22721831 10.1165/rcmb.2012-0094OC
17. Li R Song X Li G: Ibuprofen attenuates interleukin-1β-induced inflammation and actin reorganization via modulation of RhoA signaling in rabbit chondrocytes. Acta Biochim Biophys Sin (Shanghai). 2019;51(10):1026-1033. 31553428 10.1093/abbs/gmz101
18. Kunsman GW Rohrig TP: Tissue distribution of ibuprofen in a fatal overdose. Am J Forensic Med Pathol. 1993;14(1):48-50. 8493969 10.1097/00000433-199303000-00011
19. Veljkovic V Goeijenbier M Glisic S: In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease [version 1; peer review: 2 approved]. F1000Res. 2015;4:104. 26167272 10.12688/f1000research.6436.1 4482208
20. Zhao Y Ren J Harlos K: Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature. 2016;535(7610):169-172. 27362232 10.1038/nature18615 4947387
21. Paessler S Huang C Sencanski M: Ibuprofen as a template molecule for drug design against Ebola virus. Front Biosci (Landmark Ed). 2018;23:947-953. 28930583 10.2741/4627