메뉴 건너뛰기




Volumn 71, Issue 7, 2020, Pages E141-E150

An emerging clone, klebsiellapneumoniae carbapenemase 2-producing K. pneumoniae sequence type 16, associated with high mortality rates in a CC258-endemic setting

Author keywords

Bloodstream infections; Carbapenem resistant Enterobacteriaceae; CC258; Klebsiella pneumoniae; KPC

Indexed keywords

AMIKACIN; CARBAPENEMASE; MEROPENEM; POLYMYXIN B; YERSINIABACTIN; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE;

EID: 85081657643     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciz1095     Document Type: Article
Times cited : (47)

References (38)
  • 1
    • 85067782379 scopus 로고    scopus 로고
    • Centers for Diseases Control and Prevention. Accessed 18 January 2019
    • Centers for Diseases Control and Prevention. Carbapenem-resistant Enterobacteriaceae (CRE). Available at: https://www.cdc.gov/hai/organisms/cre/ index.html. Accessed 18 January 2019.
    • Carbapenem-resistant Enterobacteriaceae (CRE)
  • 3
    • 85097010967 scopus 로고    scopus 로고
    • Public Health England. Accessed 18 January 2019
    • Public Health England. Carbapenem resistance: guidance, data and analysis. Available at: https://www.gov.uk/government/collections/carbapenemresistance- guidance-data-and-analysis. Accessed 18 January 2019.
    • Carbapenem resistance: guidance, data and analysis
  • 4
    • 85042153859 scopus 로고    scopus 로고
    • Treatment of infections caused by extended-spectrum-beta-lactamase-, AmpC-, and carbapenemase-producing Enterobacteriaceae
    • Rodriguez-Bano J, Gutierrez-Gutierrez B, Machuca I, Pascual A. Treatment of infections caused by extended-spectrum-beta-lactamase-, AmpC-, and carbapenemase-producing Enterobacteriaceae. Clin Microbiol Rev 2018; 31.
    • (2018) Clin Microbiol Rev , vol.31
    • Rodriguez-Bano, J1    Gutierrez-Gutierrez, B2    Machuca, I3    Pascual, A.4
  • 5
    • 85055262411 scopus 로고    scopus 로고
    • KPC-producing Klebsiella pneumoniae bloodstream isolates from Brazilian hospitals: what (still) remains active?
    • Antochevis LC, Magagnin CM, Nunes AG, et al. KPC-producing Klebsiella pneumoniae bloodstream isolates from Brazilian hospitals: what (still) remains active? J Glob Antimicrob Resist 2018; 15:173-7.
    • (2018) J Glob Antimicrob Resist , vol.15 , pp. 173-177
    • Antochevis, LC1    Magagnin, CM2    Nunes, AG3
  • 6
    • 84999816126 scopus 로고    scopus 로고
    • Ceftazidime-avibactam in ceftazidime-resistant infections
    • Raut S, Adhikari B. Ceftazidime-avibactam in ceftazidime-resistant infections. Lancet Infect Dis 2016; 16:997.
    • (2016) Lancet Infect Dis , vol.16 , pp. 997
    • Raut, S1    Adhikari, B.2
  • 7
    • 84882712084 scopus 로고    scopus 로고
    • Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases
    • Munoz-Price LS, Poirel L, Bonomo RA, et al. Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. Lancet Infect Dis 2013; 13:785-96.
    • (2013) Lancet Infect Dis , vol.13 , pp. 785-796
    • Munoz-Price, LS1    Poirel, L2    Bonomo, RA3
  • 8
    • 62749195559 scopus 로고    scopus 로고
    • The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria
    • Nordmann P, Cuzon G, Naas T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis 2009; 9:228-36.
    • (2009) Lancet Infect Dis , vol.9 , pp. 228-236
    • Nordmann, P1    Cuzon, G2    Naas, T.3
  • 10
    • 84904015627 scopus 로고    scopus 로고
    • Epidemic Klebsiella pneumoniae ST258 is a hybrid strain
    • Chen L, Mathema B, Pitout JD, DeLeo FR, Kreiswirth BN. Epidemic Klebsiella pneumoniae ST258 is a hybrid strain. MBio 2014; 5:e01355-14.
    • (2014) MBio , vol.5 , pp. e01355-14
    • Chen, L1    Mathema, B2    Pitout, JD3    DeLeo, FR4    Kreiswirth, BN.5
  • 11
    • 85018340506 scopus 로고    scopus 로고
    • Nationwide surveillance of clinical carbapenemresistant Enterobacteriaceae (CRE) strains in China
    • Zhang R, Liu L, Zhou H, et al. Nationwide surveillance of clinical carbapenemresistant Enterobacteriaceae (CRE) strains in China. EBioMedicine 2017; 19:98-106.
    • (2017) EBioMedicine , vol.19 , pp. 98-106
    • Zhang, R1    Liu, L2    Zhou, H3
  • 12
    • 85028557993 scopus 로고    scopus 로고
    • A fatal outbreak of ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae in a Chinese hospital: a molecular epidemiological study
    • Gu D, Dong N, Zheng Z, et al. A fatal outbreak of ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae in a Chinese hospital: a molecular epidemiological study. Lancet Infect Dis 2018; 18:37-46.
    • (2018) Lancet Infect Dis , vol.18 , pp. 37-46
    • Gu, D1    Dong, N2    Zheng, Z3
  • 13
    • 84988499049 scopus 로고    scopus 로고
    • Polymyxin B resistance in carbapenem-resistant Klebsiella pneumoniae, Sao Paulo, Brazil
    • Bartolleti F, Seco BM, Capuzzo Dos Santos C, et al. Polymyxin B resistance in carbapenem-resistant Klebsiella pneumoniae, Sao Paulo, Brazil. Emerg Infect Dis 2016; 22:1849-51.
    • (2016) Emerg Infect Dis , vol.22 , pp. 1849-1851
    • Bartolleti, F1    Seco, BM2    Capuzzo Dos Santos, C3
  • 14
    • 79959195195 scopus 로고    scopus 로고
    • Dissemination of blaKPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil
    • Andrade LN, Curiao T, Ferreira JC, et al. Dissemination of blaKPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil. Antimicrob Agents Chemother 2011; 55:3579-83.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 3579-3583
    • Andrade, LN1    Curiao, T2    Ferreira, JC3
  • 15
    • 85041694976 scopus 로고    scopus 로고
    • Temporal evolution of polymyxin B-resistant Klebsiella pneumoniae clones recovered from blood cultures in a teaching hospital during a 7-year period
    • Braun G, Cayo R, Matos AP, de Mello Fonseca J, Gales AC. Temporal evolution of polymyxin B-resistant Klebsiella pneumoniae clones recovered from blood cultures in a teaching hospital during a 7-year period. Int J Antimicrob Agents 2018; 51:522-7.
    • (2018) Int J Antimicrob Agents , vol.51 , pp. 522-527
    • Braun, G1    Cayo, R2    Matos, AP3    de Mello Fonseca, J4    Gales, AC.5
  • 16
    • 84872399178 scopus 로고    scopus 로고
    • Update of the molecular epidemiology of KPC-2-producing Klebsiella pneumoniae in Brazil: spread of clonal complex 11 (ST11, ST437 and ST340)
    • Pereira PS, de Araujo CF, Seki LM, Zahner V, Carvalho-Assef AP, Asensi MD. Update of the molecular epidemiology of KPC-2-producing Klebsiella pneumoniae in Brazil: spread of clonal complex 11 (ST11, ST437 and ST340). J Antimicrob Chemother 2013; 68:312-6.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 312-316
    • Pereira, PS1    de Araujo, CF2    Seki, LM3    Zahner, V4    Carvalho-Assef, AP5    Asensi, MD.6
  • 17
    • 79955973511 scopus 로고    scopus 로고
    • Molecular epidemiology of KPC-2- producing Klebsiella pneumoniae isolates in Brazil: the predominance of sequence type 437
    • Seki LM, Pereira PS, de Souza Mda P, et al. Molecular epidemiology of KPC-2- producing Klebsiella pneumoniae isolates in Brazil: the predominance of sequence type 437. Diagn Microbiol Infect Dis 2011; 70:274-7.
    • (2011) Diagn Microbiol Infect Dis , vol.70 , pp. 274-277
    • Seki, LM1    Pereira, PS2    de Souza Mda, P3
  • 18
    • 85042078559 scopus 로고    scopus 로고
    • Virulence genes, capsular and plasmid types of multidrug-resistant CTX-M(-2, -8, -15) and KPC-2-producing Klebsiella pneumoniae isolates from four major hospitals in Brazil
    • Andrade LN, Novais A, Stegani LMM, et al. Virulence genes, capsular and plasmid types of multidrug-resistant CTX-M(-2, -8, -15) and KPC-2-producing Klebsiella pneumoniae isolates from four major hospitals in Brazil. Diagn Microbiol Infect Dis 2018; 91:164-8.
    • (2018) Diagn Microbiol Infect Dis , vol.91 , pp. 164-168
    • Andrade, LN1    Novais, A2    Stegani, LMM3
  • 19
    • 85070816519 scopus 로고    scopus 로고
    • European Committee on Antimicrobial Susceptibility Testing. Accessed 22 September 2018
    • European Committee on Antimicrobial Susceptibility Testing. Clinical breakpoints and dosing of antibiotics. Available at: http://www.eucast.org/clinical- breakpoints/. Accessed 22 September 2018.
    • Clinical breakpoints and dosing of antibiotics
  • 20
    • 85097005971 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. Accessed 15 September 2017
    • Centers for Disease Control and Prevention. PulseNet standard protocol. Available at: https://www.cdc.gov/pulsenet/pdf/ecoli-shigella-salmonella-pfgeprotocol- 508c.pdf. Accessed 15 September 2017.
    • PulseNet standard protocol
  • 22
    • 85037850794 scopus 로고    scopus 로고
    • Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms
    • Yang Q, Li M, Spiller OB, et al. Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms. Nat Commun 2017; 8:2054.
    • (2017) Nat Commun , vol.8 , pp. 2054
    • Yang, Q1    Li, M2    Spiller, OB3
  • 23
    • 84936929460 scopus 로고    scopus 로고
    • Infections caused by KPC-producing Klebsiella pneumoniae: differences in therapy and mortality in a multicentre study
    • ISGRI-SITA (Italian Study Group on Resistant Infections of the Societa Italiana Terapia Antinfettiva)
    • Tumbarello M, Trecarichi EM, De Rosa FG, et al; ISGRI-SITA (Italian Study Group on Resistant Infections of the Societa Italiana Terapia Antinfettiva). Infections caused by KPC-producing Klebsiella pneumoniae: differences in therapy and mortality in a multicentre study. J Antimicrob Chemother 2015; 70:2133-43.
    • (2015) J Antimicrob Chemother , vol.70 , pp. 2133-2143
    • Tumbarello, M1    Trecarichi, EM2    De Rosa, FG3
  • 24
    • 84961778036 scopus 로고    scopus 로고
    • Predictors of outcome in ICU patients with septic shock caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae
    • Falcone M, Russo A, Iacovelli A, et al. Predictors of outcome in ICU patients with septic shock caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae. Clin Microbiol Infect 2016; 22:444-50.
    • (2016) Clin Microbiol Infect , vol.22 , pp. 444-450
    • Falcone, M1    Russo, A2    Iacovelli, A3
  • 25
    • 85018723782 scopus 로고    scopus 로고
    • Effect of appropriate combination therapy on mortality of patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae (INCREMENT): a retrospective cohort study
    • REIPI/ESGBIS INCREMENT Investigators
    • Gutierrez-Gutierrez B, Salamanca E, de Cueto M, et al; REIPI/ESGBIS/ INCREMENT Investigators. Effect of appropriate combination therapy on mortality of patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae (INCREMENT): a retrospective cohort study. Lancet Infect Dis 2017; 17:726-34.
    • (2017) Lancet Infect Dis , vol.17 , pp. 726-734
    • Gutierrez-Gutierrez, B1    Salamanca, E2    de Cueto, M3
  • 26
    • 84941185133 scopus 로고    scopus 로고
    • Investigation of a possible outbreak of NDM-5-producing ST16 Klebsiella pneumoniae among patients in Denmark with no history of recent travel using whole-genome sequencing
    • Hammerum AM, Hansen F, Olesen B, et al. Investigation of a possible outbreak of NDM-5-producing ST16 Klebsiella pneumoniae among patients in Denmark with no history of recent travel using whole-genome sequencing. J Glob Antimicrob Resist 2015; 3:219-21.
    • (2015) J Glob Antimicrob Resist , vol.3 , pp. 219-221
    • Hammerum, AM1    Hansen, F2    Olesen, B3
  • 27
    • 84964322336 scopus 로고    scopus 로고
    • Phylogeny, resistome and mobile genetic elements of emergent OXA-48 and OXA-245 Klebsiella pneumoniae clones circulating in Spain
    • Perez-Vazquez M, Oteo J, Garcia-Cobos S, et al. Phylogeny, resistome and mobile genetic elements of emergent OXA-48 and OXA-245 Klebsiella pneumoniae clones circulating in Spain. J Antimicrob Chemother 2016; 71:887-96.
    • (2016) J Antimicrob Chemother , vol.71 , pp. 887-896
    • Perez-Vazquez, M1    Oteo, J2    Garcia-Cobos, S3
  • 28
    • 85014774355 scopus 로고    scopus 로고
    • Evolution and epidemiology of multidrug-resistant Klebsiella pneumoniae in the United Kingdom and Ireland
    • Moradigaravand D, Martin V, Peacock SJ, Parkhill J. Evolution and epidemiology of multidrug-resistant Klebsiella pneumoniae in the United Kingdom and Ireland. MBio 2017; 8.
    • (2017) MBio , vol.8
    • Moradigaravand, D1    Martin, V2    Peacock, SJ3    Parkhill, J.4
  • 29
    • 84965090285 scopus 로고    scopus 로고
    • Isolation of an NDM-5-producing ST16 Klebsiella pneumoniae from a Dutch patient without travel history abroad, August 2015
    • Bathoorn E, Rossen JW, Lokate M, Friedrich AW, Hammerum AM. Isolation of an NDM-5-producing ST16 Klebsiella pneumoniae from a Dutch patient without travel history abroad, August 2015. Euro Surveill 2015; 20.
    • (2015) Euro Surveill , vol.20
    • Bathoorn, E1    Rossen, JW2    Lokate, M3    Friedrich, AW4    Hammerum, AM.5
  • 30
    • 85030649068 scopus 로고    scopus 로고
    • Co-production of NDM-1 and OXA-232 by ST16 Klebsiella pneumoniae, Italy, 2016
    • Avolio M, Vignaroli C, Crapis M, Camporese A. Co-production of NDM-1 and OXA-232 by ST16 Klebsiella pneumoniae, Italy, 2016. Future Microbiol 2017; 12: 1119-22.
    • (2017) Future Microbiol , vol.12 , pp. 1119-1122
    • Avolio, M1    Vignaroli, C2    Crapis, M3    Camporese, A.4
  • 31
    • 84939839312 scopus 로고    scopus 로고
    • Clonal dissemination of OXA-370- producing Klebsiella pneumoniae in Rio de Janeiro, Brazil
    • Pereira PS, Borghi M, de Araujo CF, et al. Clonal dissemination of OXA-370- producing Klebsiella pneumoniae in Rio de Janeiro, Brazil. Antimicrob Agents Chemother 2015; 59:4453-6.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 4453-4456
    • Pereira, PS1    Borghi, M2    de Araujo, CF3
  • 32
    • 85072628333 scopus 로고    scopus 로고
    • Ceftazidime-avibactam as salvage therapy for infections caused by Enterobacteriales coresistant to carbapenems and polymyxins
    • Guimaraes T, Nouer SA, Martins RCR, et al. Ceftazidime-avibactam as salvage therapy for infections caused by Enterobacteriales coresistant to carbapenems and polymyxins. Antimicrob Agents Chemother 2019; 63.
    • (2019) Antimicrob Agents Chemother , vol.63
    • Guimaraes, T1    Nouer, SA2    Martins, RCR3
  • 33
    • 85059797468 scopus 로고    scopus 로고
    • Spread of Carbapenem and colistin-resistant Klebsiella pneumoniae ST512 clinical isolates in Israel: a cause for vigilance
    • Lalaoui R, Bakour S, Livnat K, Assous MV, Diene SM, Rolain JM. Spread of Carbapenem and colistin-resistant Klebsiella pneumoniae ST512 clinical isolates in Israel: a cause for vigilance. Microb Drug Resist 2019; 25:63-71.
    • (2019) Microb Drug Resist , vol.25 , pp. 63-71
    • Lalaoui, R1    Bakour, S2    Livnat, K3    Assous, MV4    Diene, SM5    Rolain, JM.6
  • 34
    • 85014763260 scopus 로고    scopus 로고
    • The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones of Klebsiella pneumoniae ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3
    • Spanish Antibiotic Resistance Surveillance Program Collaborating Group
    • Oteo J, Perez-Vazquez M, Bautista V, et al; Spanish Antibiotic Resistance Surveillance Program Collaborating Group. The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones of Klebsiella pneumoniae ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3. J Antimicrob Chemother 2016; 71:3392-9.
    • (2016) J Antimicrob Chemother , vol.71 , pp. 3392-3399
    • Oteo, J1    Perez-Vazquez, M2    Bautista, V3
  • 35
    • 85041135672 scopus 로고    scopus 로고
    • Diversity, virulence, and antimicrobial resistance of the KPC-producing Klebsiella pneumoniae ST307 clone
    • Villa L, Feudi C, Fortini D, et al. Diversity, virulence, and antimicrobial resistance of the KPC-producing Klebsiella pneumoniae ST307 clone. Microb Genom 2017; 3:e000110.
    • (2017) Microb Genom , vol.3 , pp. e000110
    • Villa, L1    Feudi, C2    Fortini, D3
  • 36
    • 85047019497 scopus 로고    scopus 로고
    • Impact of the ST101 clone on fatality among patients with colistin-resistant Klebsiella pneumoniae infection
    • Can F, Menekse S, Ispir P, et al. Impact of the ST101 clone on fatality among patients with colistin-resistant Klebsiella pneumoniae infection. J Antimicrob Chemother 2018; 73:1235-41.
    • (2018) J Antimicrob Chemother , vol.73 , pp. 1235-1241
    • Can, F1    Menekse, S2    Ispir, P3
  • 37
    • 84992697219 scopus 로고    scopus 로고
    • Outbreak of KPC-3-producing ST15 and ST348 Klebsiella pneumoniae in a Portuguese hospital
    • Vubil D, Figueiredo R, Reis T, Canha C, Boaventura L, DA Silva GJ. Outbreak of KPC-3-producing ST15 and ST348 Klebsiella pneumoniae in a Portuguese hospital. Epidemiol Infect 2017; 145:595-9.
    • (2017) Epidemiol Infect , vol.145 , pp. 595-599
    • Vubil, D1    Figueiredo, R2    Reis, T3    Canha, C4    Boaventura, L5    DA Silva, GJ.6
  • 38
    • 84884258175 scopus 로고    scopus 로고
    • KPC-producing, multidrugresistant Klebsiella pneumoniae sequence type 258 as a typical opportunistic pathogen
    • Tzouvelekis LS, Miriagou V, Kotsakis SD, et al. KPC-producing, multidrugresistant Klebsiella pneumoniae sequence type 258 as a typical opportunistic pathogen. Antimicrob Agents Chemother 2013; 57:5144-6.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 5144-5146
    • Tzouvelekis, LS1    Miriagou, V2    Kotsakis, SD3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.