Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity

Immunity

Volumn 52, Issue 1, 2020, Pages 136-150.e6

  Morris, Anna B ^a   Farley, Clara R ^a   Pinelli, David F ^a   Adams, Layne E ^a   Cragg, Mark S ^b   Boss, Jeremy M ^a   Scharer, Christopher D ^a   Fribourg, Miguel ^c   Cravedi, Paolo ^c   Heeger, Peter S ^c   Ford, Mandy L ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; CD8+ T cells; FcgRIIB; Fgl2; transplantation; tumor immunology

Indexed keywords

CASPASE 3; CASPASE 7; CYTOKINE; FC RECEPTOR; FC RECEPTOR FCGAMMARIIB; FIBRIN OGEN LIKE 2; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASP7 PROTEIN, HUMAN; FCGR2B PROTEIN, HUMAN; FGL2 PROTEIN, HUMAN; FIBRINOGEN; IMMUNOGLOBULIN G;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CELL DIVISION; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; GENE DELETION; GRAFT REJECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ADULT; AGED; ANIMAL; C57BL MOUSE; EXPERIMENTAL MELANOMA; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; KNOCKOUT MOUSE; MIDDLE AGED; TUMOR CELL LINE; YOUNG ADULT;

ADULT; AGED; ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 7; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; FEMALE; FIBRINOGEN; GRAFT REJECTION; HUMANS; IMMUNOGLOBULIN G; IMMUNOSUPPRESSION; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; RECEPTORS, IGG; YOUNG ADULT;

EID: 85077630536     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2019.12.006     Document Type: Article

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