Fluoxetine for motor recovery after acute intracerebral hemorrhage, the FMRICH trial

Clinical Neurology and Neurosurgery

Volumn 190, Issue , 2020, Pages

  Marquez Romero, Juan Manuel ^a   Reyes Martínez, Maricela ^b   Huerta Franco, María Raquel ^c   Ruiz Franco, Angélica ^d   Silos, Humberto ^d   Arauz, Antonio ^d  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^b Hospital De Alta Especialidad Dr Juan Graham Casasus   (Mexico)

^c UNIVERSITY OF GUANAJUATO   (Mexico)

^d NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

Author keywords

Cerebral hemorrhage; Clinical trial; Fluoxetine; Recovery of function; Stroke

Indexed keywords

FLUOXETINE; PLACEBO; SEROTONIN UPTAKE INHIBITOR;

ACUTE DISEASE; ADULT; ARTICLE; BARTHEL INDEX; BASAL GANGLION; BRAIN HEMORRHAGE; CLINICAL ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DIARRHEA; DOUBLE BLIND PROCEDURE; DROWSINESS; FEMALE; FOLLOW UP; HEMATOMA; HUMAN; HYPERTENSION; INSOMNIA; MALE; MIDDLE AGED; MOTOR PERFORMANCE; MULTICENTER STUDY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NAUSEA; RANDOMIZED CONTROLLED TRIAL; RANKIN SCALE; SEXUAL DYSFUNCTION; AGED; BASAL GANGLION HEMORRHAGE; CLINICAL TRIAL; PATHOPHYSIOLOGY; STROKE REHABILITATION; TREATMENT OUTCOME;

AGED; BASAL GANGLIA HEMORRHAGE; DOUBLE-BLIND METHOD; FEMALE; FLUOXETINE; HEMORRHAGIC STROKE; HUMANS; INTRACRANIAL HEMORRHAGE, HYPERTENSIVE; MALE; MIDDLE AGED; RECOVERY OF FUNCTION; SEROTONIN UPTAKE INHIBITORS; STROKE REHABILITATION; TREATMENT OUTCOME;

EID: 85077023505     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2019.105656     Document Type: Article

References (19)

1. Pandian, J.D., William, A.G., Kate, M.P., et al. Strategies to improve stroke care services in low- and middle-income countries: a systematic review. Neuroepidemiology 49 (2017), 45–61.
2. Krishnamurthi, R.V., Feigin, V.L., Forouzanfar, M.H., et al. Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990-2010: findings from the Global Burden of Disease Study. Lancet Glob. Health 2013:1 (2010), e259–281.
3. Feigin, V.L., Forouzanfar, M.H., Krishnamurthi, R., et al. Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study. Lancet 2014:383 (2010), 245–254.
4. Dastur, C.K., Yu, W., Current management of spontaneous intracerebral haemorrhage. Stroke Vasc. Neurol. 2 (2017), 21–29.
5. Mead, G.E., Hsieh, C.F., Lee, R., et al. Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. Cochrane Database Syst. Rev., 11, 2012 CD009286.
6. Siepmann, T., Penzlin, A.I., Kepplinger, J., et al. Selective serotonin reuptake inhibitors to improve outcome in acute ischemic stroke: possible mechanisms and clinical evidence. Brain Behav., 5, 2015, e00373.
7. Marquez-Romero, J.M., Arauz, A., Ruiz-Sandoval, J.L., et al. Fluoxetine for motor recovery after acute intracerebral hemorrhage (FMRICH): study protocol for a randomized, double-blind, placebo-controlled, multicenter trial. Trials, 14, 2013, 77.
8. Chollet, F., Tardy, J., Albucher, J.F., et al. Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial. Lancet Neurol. 10 (2011), 123–130.
9. Stinear, C., Prediction of recovery of motor function after stroke. Lancet Neurol. 9 (2010), 1228–1232 (Review).
10. Donnan, G.A., Fisher, M., Macleod, M., et al. Stroke. Lancet 371 (2008), 1612–1623 (Review).
11. Kraglund, K.L., Mortensen, J.K., Damsbo, A.G., et al. Neuroregeneration and vascular protection by citalopram in acute ischemic stroke (TALOS). Stroke 49 (2018), 2568–2576.
12. Collaboration, F.T., Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial. Lancet 393 (2019), 265–274.
13. Owolabi, M.O., Akarolo-Anthony, S., Akinyemi, R., et al. The burden of stroke in Africa: a glance at the present and a glimpse into the future. Cardiovasc. J. Afr. 26 (2015), S27–38.
14. Regenhardt, R.W., Biseko, M.R., Shayo, A.F., et al. Opportunities for intervention: stroke treatments, disability and mortality in urban Tanzania. Int. J. Qual. Health Care 31 (2019), 385–392.
15. Jesus, T.S., Landry, M.D., Hoenig, H., Global need for physical rehabilitation: systematic analysis from the global burden of disease study. Int. J. Environ. Res. Public Health, 2019, 2017, 16.
16. Savadi Oskouie, D., Sharifipour, E., Sadeghi Bazargani, H., et al. Efficacy of citalopram on acute ischemic stroke outcome: a randomized clinical trial. Neurorehabil. Neural Repair 31 (2017), 638–647.
17. He, Y.T., Tang, B.S., Cai, Z.L., et al. Effects of fluoxetine on neural functional prognosis after ischemic stroke: a randomized controlled study in China. J. Stroke Cerebrovasc. Dis. 25 (2016), 761–770.
18. Huang, J., Liu, X., Luo, X., et al. Effects of Fluoxetine on Poststroke Dysphagia: A Clinical Retrospective Study. J. Stroke Cerebrovasc. Dis., 2018.
19. Yeo, S.H., Lim, Z.I., Mao, J., et al. Effects of central nervous system drugs on recovery after stroke: a systematic review and meta-analysis of randomized controlled trials. Clin. Drug Investig. 37 (2017), 901–928.